Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity Article Swipe

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Egle Kvedaraite , Laura Hertwig , Indranil Sinha , Andrea Ponzetta , Ida Hed Myrberg , Magda Lourda , Majda Dzidic , Mira Akber , Jonas Klingström , Elin Folkesson , Jagadeeswara Rao Muvva , Puran Chen , Sara Gredmark‐Russ , Susanna Brighenti , Anna Norrby‐Teglund , Lars I. Eriksson , Olav Rooyackers , Soo Aleman , Kristoffer Strålin , Hans‐Gustaf Ljunggren , Florent Ginhoux , Niklas K. Björkström , Jan‐Inge Henter , Mattias Svensson , John Tyler Sandberg , Helena Bergsten , Niklas K. Björkström , Susanna Brighenti , Marcus Buggert , Marta Butrym , Benedict J. Chambers , Puran Chen , Martin Cornillet , Angélica Cuapio , Isabel Diaz Lozano , Majda Dzidic , Johanna Emgård , Malin Flodström‐Tullberg , Jean‐Baptiste Gorin , Sara Gredmark‐Russ , Alvaro Haroun-Izquierdo , Laura Hertwig , Sadaf Kalsum , Jonas Klingström , Efthymia Kokkinou , Egle Kvedaraite , Hans‐Gustaf Ljunggren , Nicole Marquardt , Magda Lourda , Kimia T. Maleki , Karl‐Johan Malmberg , Jakob Michaëlsson , Jenny Mjösberg , Kirsten Moll , Jagadeeswara Rao Muvva , Anna Norrby‐Teglund , Laura M. Palma Medina , Tiphaine Parrot , Lena Radler , Emma Ringqvist , Johan K. Sandberg , Takuya Sekine , Tea Soini , Mattias Svensson , Janne Tynell , Andreas von Kries , David Wullimann , André Perez‐Potti , Olga Rivera‐Ballesteros , Christopher Maucourant , Renata Varnaitė , Mira Akber , Lena Berglin , Demi Brownlie , Marco Giulio Loreti , Ebba Sohlberg , Tobias Kammann , Elisabet Welin Henriksson , Kristoffer Strålin , Soo Aleman , Anders Sönnerborg , Lena Dillner , Anna Färnert , Hedvig Glans , Pontus Nauclér , Olav Rooyackers , Johan Mårtensson , Lars I. Eriksson , Björn P. Persson , Jonathan Grip , Christian Unge ·

YOU? · · 2021 · Open Access · · DOI: https://doi.org/10.1073/pnas.2018587118

Significance While broad efforts toward getting an overview of immune cell and soluble factor alterations in COVID-19 are under way, a deep and comprehensive understanding of the mononuclear phagocyte system, including circulating progenitors, is still largely lacking. This study provides a reference for the mononuclear phagocyte response to SARS-CoV-2 infection and unravels mononuclear phagocyte dysregulations associated with severe COVID-19.

Related Topics

Infectious Diseases (Medical Specialty)

Outbreak (2024 Film)

Concepts

Coronavirus disease 2019 (COVID-19) Mononuclear phagocyte system 2019-20 coronavirus outbreak Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Phagocyte Medicine Immunology Virology Pathology Disease Phagocytosis Infectious disease (medical specialty) Outbreak

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Type: article
Language: en
Landing Page: https://doi.org/10.1073/pnas.2018587118
OA Status: hybrid
Cited By: 129
References: 59
Related Works: 10
OpenAlex ID: https://openalex.org/W3125110844

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OpenAlex ID: https://openalex.org/W3125110844

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DOI: https://doi.org/10.1073/pnas.2018587118

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Title: Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity

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Type: article

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Language: en

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Publication year: 2021

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Publication date: 2021-01-21

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Authors: Egle Kvedaraite, Laura Hertwig, Indranil Sinha, Andrea Ponzetta, Ida Hed Myrberg, Magda Lourda, Majda Dzidic, Mira Akber, Jonas Klingström, Elin Folkesson, Jagadeeswara Rao Muvva, Puran Chen, Sara Gredmark‐Russ, Susanna Brighenti, Anna Norrby‐Teglund, Lars I. Eriksson, Olav Rooyackers, Soo Aleman, Kristoffer Strålin, Hans‐Gustaf Ljunggren, Florent Ginhoux, Niklas K. Björkström, Jan‐Inge Henter, Mattias Svensson, John Tyler Sandberg, Helena Bergsten, Niklas K. Björkström, Susanna Brighenti, Marcus Buggert, Marta Butrym, Benedict J. Chambers, Puran Chen, Martin Cornillet, Angélica Cuapio, Isabel Diaz Lozano, Majda Dzidic, Johanna Emgård, Malin Flodström‐Tullberg, Jean‐Baptiste Gorin, Sara Gredmark‐Russ, Alvaro Haroun-Izquierdo, Laura Hertwig, Sadaf Kalsum, Jonas Klingström, Efthymia Kokkinou, Egle Kvedaraite, Hans‐Gustaf Ljunggren, Nicole Marquardt, Magda Lourda, Kimia T. Maleki, Karl‐Johan Malmberg, Jakob Michaëlsson, Jenny Mjösberg, Kirsten Moll, Jagadeeswara Rao Muvva, Anna Norrby‐Teglund, Laura M. Palma Medina, Tiphaine Parrot, Lena Radler, Emma Ringqvist, Johan K. Sandberg, Takuya Sekine, Tea Soini, Mattias Svensson, Janne Tynell, Andreas von Kries, David Wullimann, André Perez‐Potti, Olga Rivera‐Ballesteros, Christopher Maucourant, Renata Varnaitė, Mira Akber, Lena Berglin, Demi Brownlie, Marco Giulio Loreti, Ebba Sohlberg, Tobias Kammann, Elisabet Welin Henriksson, Kristoffer Strålin, Soo Aleman, Anders Sönnerborg, Lena Dillner, Anna Färnert, Hedvig Glans, Pontus Nauclér, Olav Rooyackers, Johan Mårtensson, Lars I. Eriksson, Björn P. Persson, Jonathan Grip, Christian Unge

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Landing page: https://doi.org/10.1073/pnas.2018587118

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OA status: hybrid

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OA URL: https://doi.org/10.1073/pnas.2018587118

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Concepts: Coronavirus disease 2019 (COVID-19), Mononuclear phagocyte system, 2019-20 coronavirus outbreak, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Phagocyte, Medicine, Immunology, Virology, Pathology, Disease, Phagocytosis, Infectious disease (medical specialty), Outbreak

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Cited by: 129

Total citation count in OpenAlex
Citations by year (recent): 2025: 7, 2024: 9, 2023: 22, 2022: 47, 2021: 44

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References (count): 59

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Related works (count): 10

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