Manufacturing of porous polymer films as a basis for the novel cardiovascular implant devices Article Swipe

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Implant Porosity Materials science Polymer Basis (linear algebra) Biomedical engineering Composite material Medicine Surgery Mathematics Geometry

Thomas Reske , Daniela Koper , Sebastian Kaule , Bradley Merryweather , Valeria Khaimov , Niels Grabow , Klaus-Peter Schmitz , Stefan Siewert ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1515/cdbme-2024-2128 · OA: W4405554691

For applications in the cardiovascular field, the production of tailored biomaterials such as those required for insulations or patches is a key technology. In this work we were able to manufacture thermoplastic silicone polycarbonate elastomer scaffolds with a porous external surface. The samples were produced using the dip coating process. Pores were created using the salt leaching technique. The complete removal of the salt was verified by Raman microscopy. The absence of solvents was demonstrated by biocompatibility tests using an endothelial cell line. The potential functionality of the system was thus demonstrated. The next step will focus on promoting the adhesion of suitable cells for specific applications.