Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspring Article Swipe
Elise Turk
,
Marion I. van den Heuvel
,
Charlotte Sleurs
,
Thibo Billiet
,
Anne Uyttebroeck
,
Stefan Sunaert
,
Maarten Mennes
,
Bea Van den Bergh
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1897872/v1
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1897872/v1
Background. The connectome, constituting a unique fingerprint of a person’s brain, may be influenced by its prenatal environment, potentially affecting later-life resilience and mental health. Methods. We conducted a prospective resting-state functional Magnetic Resonance Imaging study in 28-year-old offspring (N=49) of mothers whose anxiety was monitored during pregnancy. Two offspring anxiety subgroups were defined: “High anxiety” (N=13) group versus “low-to-medium anxiety” (N=36) group, based on maternal self-reported state anxiety at 12-22 weeks of gestation. To predict resting-state functional connectivity, maternal state anxiety during pregnancy was included as a predictor in general linear models for both ROI-to-ROI and graph theoretical metrics. Sex, birth weight and postnatal anxiety were included as covariates. Results. Higher maternal anxiety was associated with weaker functional connectivity of medial prefrontal cortex with left inferior frontal gyrus and left lateral prefontal cortex with left somatosensory motor gyrus in the offspring. While our results showed a general pattern of lower functional connectivity in adults prenatally exposed to maternal anxiety, we did not observe significant differences in global brain networks between groups. Conclusions. Weaker (medial) prefrontal cortex functional connectivity in the high anxiety adult offspring group suggests a long-term negative impact of prenatal exposure to high maternal anxiety, extending into adulthood. To prevent mental health problems at population level, universal primary prevention strategies should aim at lowering maternal anxiety during pregnancy.
Related Topics
Concepts
Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-1897872/v1
- https://www.researchsquare.com/article/rs-1897872/latest.pdf
- OA Status
- green
- Cited By
- 2
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4289261356
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4289261356Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.21203/rs.3.rs-1897872/v1Digital Object Identifier
- Title
-
Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspringWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-08-01Full publication date if available
- Authors
-
Elise Turk, Marion I. van den Heuvel, Charlotte Sleurs, Thibo Billiet, Anne Uyttebroeck, Stefan Sunaert, Maarten Mennes, Bea Van den BerghList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-1897872/v1Publisher landing page
- PDF URL
-
https://www.researchsquare.com/article/rs-1897872/latest.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.researchsquare.com/article/rs-1897872/latest.pdfDirect OA link when available
- Concepts
-
Anxiety, Offspring, Prefrontal cortex, Psychology, Pregnancy, Resting state fMRI, Population, Functional magnetic resonance imaging, Psychiatry, Clinical psychology, Medicine, Neuroscience, Cognition, Biology, Environmental health, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
46Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4289261356 |
|---|---|
| doi | https://doi.org/10.21203/rs.3.rs-1897872/v1 |
| ids.doi | https://doi.org/10.21203/rs.3.rs-1897872/v1 |
| ids.openalex | https://openalex.org/W4289261356 |
| fwci | 0.57285338 |
| type | preprint |
| title | Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspring |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T10786 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9973000288009644 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2739 |
| topics[0].subfield.display_name | Public Health, Environmental and Occupational Health |
| topics[0].display_name | Maternal Mental Health During Pregnancy and Postpartum |
| topics[1].id | https://openalex.org/T10241 |
| topics[1].field.id | https://openalex.org/fields/28 |
| topics[1].field.display_name | Neuroscience |
| topics[1].score | 0.9939000010490417 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2805 |
| topics[1].subfield.display_name | Cognitive Neuroscience |
| topics[1].display_name | Functional Brain Connectivity Studies |
| topics[2].id | https://openalex.org/T11184 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9835000038146973 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2735 |
| topics[2].subfield.display_name | Pediatrics, Perinatology and Child Health |
| topics[2].display_name | Neonatal and fetal brain pathology |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C558461103 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8043956756591797 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q154430 |
| concepts[0].display_name | Anxiety |
| concepts[1].id | https://openalex.org/C112672928 |
| concepts[1].level | 3 |
| concepts[1].score | 0.7838770151138306 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q239526 |
| concepts[1].display_name | Offspring |
| concepts[2].id | https://openalex.org/C2781195155 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6044347286224365 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q18680 |
| concepts[2].display_name | Prefrontal cortex |
| concepts[3].id | https://openalex.org/C15744967 |
| concepts[3].level | 0 |
| concepts[3].score | 0.5821574926376343 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q9418 |
| concepts[3].display_name | Psychology |
| concepts[4].id | https://openalex.org/C2779234561 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5762553215026855 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11995 |
| concepts[4].display_name | Pregnancy |
| concepts[5].id | https://openalex.org/C66324658 |
| concepts[5].level | 2 |
| concepts[5].score | 0.49419596791267395 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7316120 |
| concepts[5].display_name | Resting state fMRI |
| concepts[6].id | https://openalex.org/C2908647359 |
| concepts[6].level | 2 |
| concepts[6].score | 0.4622494876384735 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q2625603 |
| concepts[6].display_name | Population |
| concepts[7].id | https://openalex.org/C2779226451 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4608575403690338 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q903809 |
| concepts[7].display_name | Functional magnetic resonance imaging |
| concepts[8].id | https://openalex.org/C118552586 |
| concepts[8].level | 1 |
| concepts[8].score | 0.4251422882080078 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q7867 |
| concepts[8].display_name | Psychiatry |
| concepts[9].id | https://openalex.org/C70410870 |
| concepts[9].level | 1 |
| concepts[9].score | 0.32676661014556885 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q199906 |
| concepts[9].display_name | Clinical psychology |
| concepts[10].id | https://openalex.org/C71924100 |
| concepts[10].level | 0 |
| concepts[10].score | 0.295594185590744 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[10].display_name | Medicine |
| concepts[11].id | https://openalex.org/C169760540 |
| concepts[11].level | 1 |
| concepts[11].score | 0.2715024948120117 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q207011 |
| concepts[11].display_name | Neuroscience |
| concepts[12].id | https://openalex.org/C169900460 |
| concepts[12].level | 2 |
| concepts[12].score | 0.22590506076812744 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q2200417 |
| concepts[12].display_name | Cognition |
| concepts[13].id | https://openalex.org/C86803240 |
| concepts[13].level | 0 |
| concepts[13].score | 0.08783465623855591 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[13].display_name | Biology |
| concepts[14].id | https://openalex.org/C99454951 |
| concepts[14].level | 1 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q932068 |
| concepts[14].display_name | Environmental health |
| concepts[15].id | https://openalex.org/C54355233 |
| concepts[15].level | 1 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[15].display_name | Genetics |
| keywords[0].id | https://openalex.org/keywords/anxiety |
| keywords[0].score | 0.8043956756591797 |
| keywords[0].display_name | Anxiety |
| keywords[1].id | https://openalex.org/keywords/offspring |
| keywords[1].score | 0.7838770151138306 |
| keywords[1].display_name | Offspring |
| keywords[2].id | https://openalex.org/keywords/prefrontal-cortex |
| keywords[2].score | 0.6044347286224365 |
| keywords[2].display_name | Prefrontal cortex |
| keywords[3].id | https://openalex.org/keywords/psychology |
| keywords[3].score | 0.5821574926376343 |
| keywords[3].display_name | Psychology |
| keywords[4].id | https://openalex.org/keywords/pregnancy |
| keywords[4].score | 0.5762553215026855 |
| keywords[4].display_name | Pregnancy |
| keywords[5].id | https://openalex.org/keywords/resting-state-fmri |
| keywords[5].score | 0.49419596791267395 |
| keywords[5].display_name | Resting state fMRI |
| keywords[6].id | https://openalex.org/keywords/population |
| keywords[6].score | 0.4622494876384735 |
| keywords[6].display_name | Population |
| keywords[7].id | https://openalex.org/keywords/functional-magnetic-resonance-imaging |
| keywords[7].score | 0.4608575403690338 |
| keywords[7].display_name | Functional magnetic resonance imaging |
| keywords[8].id | https://openalex.org/keywords/psychiatry |
| keywords[8].score | 0.4251422882080078 |
| keywords[8].display_name | Psychiatry |
| keywords[9].id | https://openalex.org/keywords/clinical-psychology |
| keywords[9].score | 0.32676661014556885 |
| keywords[9].display_name | Clinical psychology |
| keywords[10].id | https://openalex.org/keywords/medicine |
| keywords[10].score | 0.295594185590744 |
| keywords[10].display_name | Medicine |
| keywords[11].id | https://openalex.org/keywords/neuroscience |
| keywords[11].score | 0.2715024948120117 |
| keywords[11].display_name | Neuroscience |
| keywords[12].id | https://openalex.org/keywords/cognition |
| keywords[12].score | 0.22590506076812744 |
| keywords[12].display_name | Cognition |
| keywords[13].id | https://openalex.org/keywords/biology |
| keywords[13].score | 0.08783465623855591 |
| keywords[13].display_name | Biology |
| language | en |
| locations[0].id | doi:10.21203/rs.3.rs-1897872/v1 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4306402450 |
| locations[0].source.issn | |
| locations[0].source.type | repository |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Research Square (Research Square) |
| locations[0].source.host_organization | https://openalex.org/I4210096694 |
| locations[0].source.host_organization_name | Research Square (United States) |
| locations[0].source.host_organization_lineage | https://openalex.org/I4210096694 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.researchsquare.com/article/rs-1897872/latest.pdf |
| locations[0].version | acceptedVersion |
| locations[0].raw_type | posted-content |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | False |
| locations[0].raw_source_name | |
| locations[0].landing_page_url | https://doi.org/10.21203/rs.3.rs-1897872/v1 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5069387345 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-4802-6774 |
| authorships[0].author.display_name | Elise Turk |
| authorships[0].countries | NL |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I193700539 |
| authorships[0].affiliations[0].raw_affiliation_string | Tilburg University |
| authorships[0].institutions[0].id | https://openalex.org/I193700539 |
| authorships[0].institutions[0].ror | https://ror.org/04b8v1s79 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I193700539 |
| authorships[0].institutions[0].country_code | NL |
| authorships[0].institutions[0].display_name | Tilburg University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Elise Turk |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Tilburg University |
| authorships[1].author.id | https://openalex.org/A5018067682 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-2027-6234 |
| authorships[1].author.display_name | Marion I. van den Heuvel |
| authorships[1].countries | NL |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I193700539 |
| authorships[1].affiliations[0].raw_affiliation_string | Tilburg University |
| authorships[1].institutions[0].id | https://openalex.org/I193700539 |
| authorships[1].institutions[0].ror | https://ror.org/04b8v1s79 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I193700539 |
| authorships[1].institutions[0].country_code | NL |
| authorships[1].institutions[0].display_name | Tilburg University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Marion I. van den Heuvel |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Tilburg University |
| authorships[2].author.id | https://openalex.org/A5089548339 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-4480-8330 |
| authorships[2].author.display_name | Charlotte Sleurs |
| authorships[2].countries | BE |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I99464096 |
| authorships[2].affiliations[0].raw_affiliation_string | KU Leuven |
| authorships[2].institutions[0].id | https://openalex.org/I99464096 |
| authorships[2].institutions[0].ror | https://ror.org/05f950310 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I99464096 |
| authorships[2].institutions[0].country_code | BE |
| authorships[2].institutions[0].display_name | KU Leuven |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Charlotte Sleurs |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | KU Leuven |
| authorships[3].author.id | https://openalex.org/A5001679084 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-3248-5044 |
| authorships[3].author.display_name | Thibo Billiet |
| authorships[3].countries | BE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210162612 |
| authorships[3].affiliations[0].raw_affiliation_string | Icometrix (Belgium) |
| authorships[3].institutions[0].id | https://openalex.org/I4210162612 |
| authorships[3].institutions[0].ror | https://ror.org/0505c0p37 |
| authorships[3].institutions[0].type | company |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210162612 |
| authorships[3].institutions[0].country_code | BE |
| authorships[3].institutions[0].display_name | Icometrix (Belgium) |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Thibo Billiet |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Icometrix (Belgium) |
| authorships[4].author.id | https://openalex.org/A5071405091 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-5644-424X |
| authorships[4].author.display_name | Anne Uyttebroeck |
| authorships[4].countries | BE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I99464096 |
| authorships[4].affiliations[0].raw_affiliation_string | KU Leuven |
| authorships[4].institutions[0].id | https://openalex.org/I99464096 |
| authorships[4].institutions[0].ror | https://ror.org/05f950310 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I99464096 |
| authorships[4].institutions[0].country_code | BE |
| authorships[4].institutions[0].display_name | KU Leuven |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Anne Uyttebroeck |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | KU Leuven |
| authorships[5].author.id | https://openalex.org/A5000110993 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-1177-4680 |
| authorships[5].author.display_name | Stefan Sunaert |
| authorships[5].countries | BE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I99464096 |
| authorships[5].affiliations[0].raw_affiliation_string | KU Leuven |
| authorships[5].institutions[0].id | https://openalex.org/I99464096 |
| authorships[5].institutions[0].ror | https://ror.org/05f950310 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I99464096 |
| authorships[5].institutions[0].country_code | BE |
| authorships[5].institutions[0].display_name | KU Leuven |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Stefan Sunaert |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | KU Leuven |
| authorships[6].author.id | https://openalex.org/A5059324552 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-7279-3439 |
| authorships[6].author.display_name | Maarten Mennes |
| authorships[6].countries | NL |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I145872427 |
| authorships[6].affiliations[0].raw_affiliation_string | Radboud University Nijmegen |
| authorships[6].institutions[0].id | https://openalex.org/I145872427 |
| authorships[6].institutions[0].ror | https://ror.org/016xsfp80 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I145872427 |
| authorships[6].institutions[0].country_code | NL |
| authorships[6].institutions[0].display_name | Radboud University Nijmegen |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Maarten Mennes |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Radboud University Nijmegen |
| authorships[7].author.id | https://openalex.org/A5045194683 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-1560-6545 |
| authorships[7].author.display_name | Bea Van den Bergh |
| authorships[7].countries | BE |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I99464096 |
| authorships[7].affiliations[0].raw_affiliation_string | KU Leuven |
| authorships[7].institutions[0].id | https://openalex.org/I99464096 |
| authorships[7].institutions[0].ror | https://ror.org/05f950310 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I99464096 |
| authorships[7].institutions[0].country_code | BE |
| authorships[7].institutions[0].display_name | KU Leuven |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Bea Van den Bergh |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | KU Leuven |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.researchsquare.com/article/rs-1897872/latest.pdf |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspring |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10786 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9973000288009644 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2739 |
| primary_topic.subfield.display_name | Public Health, Environmental and Occupational Health |
| primary_topic.display_name | Maternal Mental Health During Pregnancy and Postpartum |
| related_works | https://openalex.org/W2601707947, https://openalex.org/W2168298321, https://openalex.org/W2387620927, https://openalex.org/W2294986132, https://openalex.org/W1964455563, https://openalex.org/W2365936003, https://openalex.org/W2790620361, https://openalex.org/W2371524820, https://openalex.org/W2319066238, https://openalex.org/W4312334884 |
| cited_by_count | 2 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2022 |
| counts_by_year[1].cited_by_count | 1 |
| locations_count | 1 |
| best_oa_location.id | doi:10.21203/rs.3.rs-1897872/v1 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4306402450 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Research Square (Research Square) |
| best_oa_location.source.host_organization | https://openalex.org/I4210096694 |
| best_oa_location.source.host_organization_name | Research Square (United States) |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I4210096694 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.researchsquare.com/article/rs-1897872/latest.pdf |
| best_oa_location.version | acceptedVersion |
| best_oa_location.raw_type | posted-content |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | |
| best_oa_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-1897872/v1 |
| primary_location.id | doi:10.21203/rs.3.rs-1897872/v1 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4306402450 |
| primary_location.source.issn | |
| primary_location.source.type | repository |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Research Square (Research Square) |
| primary_location.source.host_organization | https://openalex.org/I4210096694 |
| primary_location.source.host_organization_name | Research Square (United States) |
| primary_location.source.host_organization_lineage | https://openalex.org/I4210096694 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.researchsquare.com/article/rs-1897872/latest.pdf |
| primary_location.version | acceptedVersion |
| primary_location.raw_type | posted-content |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | False |
| primary_location.raw_source_name | |
| primary_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-1897872/v1 |
| publication_date | 2022-08-01 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W2959677035, https://openalex.org/W3046012445, https://openalex.org/W2887740321, https://openalex.org/W2540663907, https://openalex.org/W2216037864, https://openalex.org/W3108970985, https://openalex.org/W2097236372, https://openalex.org/W3111635434, https://openalex.org/W4200525351, https://openalex.org/W2116890385, https://openalex.org/W3132609649, https://openalex.org/W2120732803, https://openalex.org/W2164107386, https://openalex.org/W2953919631, https://openalex.org/W3095943671, https://openalex.org/W2946670850, https://openalex.org/W3023844846, https://openalex.org/W3006772828, https://openalex.org/W2058744155, https://openalex.org/W2092831348, https://openalex.org/W2909641863, https://openalex.org/W2148542327, https://openalex.org/W2915674157, https://openalex.org/W3183735484, https://openalex.org/W2180248447, https://openalex.org/W2071198947, https://openalex.org/W2167822639, https://openalex.org/W2512975044, https://openalex.org/W2524136091, https://openalex.org/W3017047132, https://openalex.org/W2006096283, https://openalex.org/W2765587541, https://openalex.org/W3175866482, https://openalex.org/W2887219400, https://openalex.org/W2083794024, https://openalex.org/W2066845146, https://openalex.org/W4213337628, https://openalex.org/W2153413452, https://openalex.org/W3121208659, https://openalex.org/W2766005551, https://openalex.org/W2731210387, https://openalex.org/W2979321298, https://openalex.org/W2266871031, https://openalex.org/W1983183519, https://openalex.org/W2126838454, https://openalex.org/W2613493058 |
| referenced_works_count | 46 |
| abstract_inverted_index.a | 5, 9, 29, 88, 147, 188 |
| abstract_inverted_index.To | 75, 202 |
| abstract_inverted_index.We | 27 |
| abstract_inverted_index.as | 87, 109 |
| abstract_inverted_index.at | 70, 207, 216 |
| abstract_inverted_index.be | 13 |
| abstract_inverted_index.by | 15 |
| abstract_inverted_index.in | 37, 90, 140, 154, 167, 180 |
| abstract_inverted_index.of | 8, 41, 73, 121, 150, 192 |
| abstract_inverted_index.on | 65 |
| abstract_inverted_index.to | 158, 195 |
| abstract_inverted_index.we | 161 |
| abstract_inverted_index.The | 2 |
| abstract_inverted_index.Two | 49 |
| abstract_inverted_index.aim | 215 |
| abstract_inverted_index.and | 23, 97, 104, 130 |
| abstract_inverted_index.did | 162 |
| abstract_inverted_index.for | 94 |
| abstract_inverted_index.its | 16 |
| abstract_inverted_index.may | 12 |
| abstract_inverted_index.not | 163 |
| abstract_inverted_index.our | 144 |
| abstract_inverted_index.the | 141, 181 |
| abstract_inverted_index.was | 45, 85, 115 |
| abstract_inverted_index.Sex, | 101 |
| abstract_inverted_index.both | 95 |
| abstract_inverted_index.high | 182, 196 |
| abstract_inverted_index.into | 200 |
| abstract_inverted_index.left | 126, 131, 136 |
| abstract_inverted_index.were | 53, 107 |
| abstract_inverted_index.with | 117, 125, 135 |
| abstract_inverted_index.12-22 | 71 |
| abstract_inverted_index.While | 143 |
| abstract_inverted_index.adult | 184 |
| abstract_inverted_index.based | 64 |
| abstract_inverted_index.birth | 102 |
| abstract_inverted_index.brain | 169 |
| abstract_inverted_index.graph | 98 |
| abstract_inverted_index.group | 58, 186 |
| abstract_inverted_index.gyrus | 129, 139 |
| abstract_inverted_index.lower | 151 |
| abstract_inverted_index.motor | 138 |
| abstract_inverted_index.state | 68, 81 |
| abstract_inverted_index.study | 36 |
| abstract_inverted_index.weeks | 72 |
| abstract_inverted_index.whose | 43 |
| abstract_inverted_index.(N=13) | 57 |
| abstract_inverted_index.(N=36) | 62 |
| abstract_inverted_index.(N=49) | 40 |
| abstract_inverted_index.Higher | 112 |
| abstract_inverted_index.Weaker | 174 |
| abstract_inverted_index.adults | 155 |
| abstract_inverted_index.brain, | 11 |
| abstract_inverted_index.cortex | 124, 134, 177 |
| abstract_inverted_index.during | 47, 83, 220 |
| abstract_inverted_index.global | 168 |
| abstract_inverted_index.group, | 63 |
| abstract_inverted_index.health | 205 |
| abstract_inverted_index.impact | 191 |
| abstract_inverted_index.level, | 209 |
| abstract_inverted_index.linear | 92 |
| abstract_inverted_index.medial | 122 |
| abstract_inverted_index.mental | 24, 204 |
| abstract_inverted_index.models | 93 |
| abstract_inverted_index.should | 214 |
| abstract_inverted_index.showed | 146 |
| abstract_inverted_index.unique | 6 |
| abstract_inverted_index.versus | 59 |
| abstract_inverted_index.weaker | 118 |
| abstract_inverted_index.weight | 103 |
| abstract_inverted_index.Imaging | 35 |
| abstract_inverted_index.anxiety | 44, 51, 69, 82, 106, 114, 183, 219 |
| abstract_inverted_index.between | 171 |
| abstract_inverted_index.exposed | 157 |
| abstract_inverted_index.frontal | 128 |
| abstract_inverted_index.general | 91, 148 |
| abstract_inverted_index.groups. | 172 |
| abstract_inverted_index.health. | 25 |
| abstract_inverted_index.lateral | 132 |
| abstract_inverted_index.mothers | 42 |
| abstract_inverted_index.observe | 164 |
| abstract_inverted_index.pattern | 149 |
| abstract_inverted_index.predict | 76 |
| abstract_inverted_index.prevent | 203 |
| abstract_inverted_index.primary | 211 |
| abstract_inverted_index.results | 145 |
| abstract_inverted_index.“High | 55 |
| abstract_inverted_index.(medial) | 175 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Magnetic | 33 |
| abstract_inverted_index.Methods. | 26 |
| abstract_inverted_index.Results. | 111 |
| abstract_inverted_index.anxiety, | 160, 198 |
| abstract_inverted_index.defined: | 54 |
| abstract_inverted_index.exposure | 194 |
| abstract_inverted_index.included | 86, 108 |
| abstract_inverted_index.inferior | 127 |
| abstract_inverted_index.lowering | 217 |
| abstract_inverted_index.maternal | 66, 80, 113, 159, 197, 218 |
| abstract_inverted_index.metrics. | 100 |
| abstract_inverted_index.negative | 190 |
| abstract_inverted_index.networks | 170 |
| abstract_inverted_index.prenatal | 17, 193 |
| abstract_inverted_index.problems | 206 |
| abstract_inverted_index.suggests | 187 |
| abstract_inverted_index.Resonance | 34 |
| abstract_inverted_index.affecting | 20 |
| abstract_inverted_index.conducted | 28 |
| abstract_inverted_index.extending | 199 |
| abstract_inverted_index.long-term | 189 |
| abstract_inverted_index.monitored | 46 |
| abstract_inverted_index.offspring | 39, 50, 185 |
| abstract_inverted_index.postnatal | 105 |
| abstract_inverted_index.predictor | 89 |
| abstract_inverted_index.prefontal | 133 |
| abstract_inverted_index.pregnancy | 84 |
| abstract_inverted_index.subgroups | 52 |
| abstract_inverted_index.universal | 210 |
| abstract_inverted_index.ROI-to-ROI | 96 |
| abstract_inverted_index.adulthood. | 201 |
| abstract_inverted_index.anxiety” | 56, 61 |
| abstract_inverted_index.associated | 116 |
| abstract_inverted_index.functional | 32, 78, 119, 152, 178 |
| abstract_inverted_index.gestation. | 74 |
| abstract_inverted_index.influenced | 14 |
| abstract_inverted_index.later-life | 21 |
| abstract_inverted_index.offspring. | 142 |
| abstract_inverted_index.person’s | 10 |
| abstract_inverted_index.population | 208 |
| abstract_inverted_index.prefrontal | 123, 176 |
| abstract_inverted_index.pregnancy. | 48, 221 |
| abstract_inverted_index.prenatally | 156 |
| abstract_inverted_index.prevention | 212 |
| abstract_inverted_index.resilience | 22 |
| abstract_inverted_index.strategies | 213 |
| abstract_inverted_index.28-year-old | 38 |
| abstract_inverted_index.Background. | 1 |
| abstract_inverted_index.connectome, | 3 |
| abstract_inverted_index.covariates. | 110 |
| abstract_inverted_index.differences | 166 |
| abstract_inverted_index.fingerprint | 7 |
| abstract_inverted_index.potentially | 19 |
| abstract_inverted_index.prospective | 30 |
| abstract_inverted_index.significant | 165 |
| abstract_inverted_index.theoretical | 99 |
| abstract_inverted_index.Conclusions. | 173 |
| abstract_inverted_index.connectivity | 120, 153, 179 |
| abstract_inverted_index.constituting | 4 |
| abstract_inverted_index.environment, | 18 |
| abstract_inverted_index.connectivity, | 79 |
| abstract_inverted_index.resting-state | 31, 77 |
| abstract_inverted_index.self-reported | 67 |
| abstract_inverted_index.somatosensory | 137 |
| abstract_inverted_index.“low-to-medium | 60 |
| cited_by_percentile_year.max | 94 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5069387345 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 8 |
| corresponding_institution_ids | https://openalex.org/I193700539 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7599999904632568 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.63592917 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |