MELD 3.0 in Advanced Chronic Liver Disease Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.1146/annurev-med-051322-122539
The MELD (model for end-stage liver disease) 3.0 score was developed to replace the MELD-Na score that is currently used to prioritize liver allocation for cirrhotic patients awaiting liver transplantation in the United States. The MELD 3.0 calculator includes new inputs from patient sex and serum albumin levels and has new weights for serum sodium, bilirubin, international normalized ratio, and creatinine levels. It is expected that use of MELD 3.0 scores will reduce overall waitlist mortality modestly and improve access for female liver transplant candidates. The utility of MELD 3.0 and PELD cre (pediatric end-stage liver disease, creatinine) scores for risk stratification in cirrhotic patients undergoing major abdominal surgery, placement of a transjugular intrahepatic portosystemic shunt, and other interventions requires further study. This article reviews the background of the MELD score and the rationale to create MELD 3.0 as well as potential implications of using this newer risk stratification tool in clinical practice.
Related Topics
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1146/annurev-med-051322-122539
- OA Status
- hybrid
- Cited By
- 13
- References
- 68
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387044512
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4387044512Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1146/annurev-med-051322-122539Digital Object Identifier
- Title
-
MELD 3.0 in Advanced Chronic Liver DiseaseWork title
- Type
-
reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-09-26Full publication date if available
- Authors
-
Nikhilesh R. Mazumder, Robert J. FontanaList of authors in order
- Landing page
-
https://doi.org/10.1146/annurev-med-051322-122539Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1146/annurev-med-051322-122539Direct OA link when available
- Concepts
-
Medicine, Liver disease, Transjugular intrahepatic portosystemic shunt, Liver transplantation, Creatinine, Model for End-Stage Liver Disease, Internal medicine, Portosystemic shunt, Nomogram, Chronic liver disease, Gastroenterology, Portal hypertension, Cirrhosis, Ascites, Transplantation, Intensive care medicine, SurgeryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
13Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 9, 2024: 4Per-year citation counts (last 5 years)
- References (count)
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68Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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