Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients Article Swipe

PDF

Tao Huang , Xiaoying Chen , Qingxiao Hong , Zaichun Deng , Hongying Ma , Yanfei Xin , Yong Fang , Huadan Ye , Rujie Wang , Cheng Zhang , Meng Ye , Shiwei Duan ·

YOU? · · 2015 · Open Access · · DOI: https://doi.org/10.1038/srep08897

Related Topics

Concepts

DNA methylation Lung cancer CDKN2A FHIT Methylation Oncology Cancer Population Medicine Bioinformatics Cancer research Gene Biology Internal medicine Genetics Carcinogenesis Gene expression Tumor suppressor gene Environmental health

Metadata

Type: review
Language: en
Landing Page: https://doi.org/10.1038/srep08897
PDF: https://www.nature.com/articles/srep08897.pdf
OA Status: gold
Cited By: 70
References: 39
Related Works: 10
OpenAlex ID: https://openalex.org/W2079872885

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W2079872885

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1038/srep08897

Digital Object Identifier
Title: Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients

Work title
Type: review

OpenAlex work type
Language: en

Primary language
Publication year: 2015

Year of publication
Publication date: 2015-03-10

Full publication date if available
Authors: Tao Huang, Xiaoying Chen, Qingxiao Hong, Zaichun Deng, Hongying Ma, Yanfei Xin, Yong Fang, Huadan Ye, Rujie Wang, Cheng Zhang, Meng Ye, Shiwei Duan

List of authors in order
Landing page: https://doi.org/10.1038/srep08897

Publisher landing page
PDF URL: https://www.nature.com/articles/srep08897.pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://www.nature.com/articles/srep08897.pdf

Direct OA link when available
Concepts: DNA methylation, Lung cancer, CDKN2A, FHIT, Methylation, Oncology, Cancer, Population, Medicine, Bioinformatics, Cancer research, Gene, Biology, Internal medicine, Genetics, Carcinogenesis, Gene expression, Tumor suppressor gene, Environmental health

Top concepts (fields/topics) attached by OpenAlex
Cited by: 70

Total citation count in OpenAlex
Citations by year (recent): 2025: 4, 2024: 2, 2023: 4, 2022: 2, 2021: 3

Per-year citation counts (last 5 years)
References (count): 39

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W2079872885
doi	https://doi.org/10.1038/srep08897
ids.doi	https://doi.org/10.1038/srep08897
ids.mag	2079872885
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/25754026
ids.openalex	https://openalex.org/W2079872885
fwci	5.92148344
mesh[0].qualifier_ui	Q000235
mesh[0].descriptor_ui	D014408
mesh[0].is_major_topic	False
mesh[0].qualifier_name	genetics
mesh[0].descriptor_name	Biomarkers, Tumor
mesh[1].qualifier_ui	Q000235
mesh[1].descriptor_ui	D002289
mesh[1].is_major_topic	False
mesh[1].qualifier_name	genetics
mesh[1].descriptor_name	Carcinoma, Non-Small-Cell Lung
mesh[2].qualifier_ui	Q000473
mesh[2].descriptor_ui	D002289
mesh[2].is_major_topic	False
mesh[2].qualifier_name	pathology
mesh[2].descriptor_name	Carcinoma, Non-Small-Cell Lung
mesh[3].qualifier_ui
mesh[3].descriptor_ui	D002681
mesh[3].is_major_topic	False
mesh[3].qualifier_name
mesh[3].descriptor_name	China
mesh[4].qualifier_ui	Q000235
mesh[4].descriptor_ui	D019941
mesh[4].is_major_topic	False
mesh[4].qualifier_name	genetics
mesh[4].descriptor_name	Cyclin-Dependent Kinase Inhibitor p16
mesh[5].qualifier_ui	Q000235
mesh[5].descriptor_ui	D019175
mesh[5].is_major_topic	False
mesh[5].qualifier_name	genetics
mesh[5].descriptor_name	DNA Methylation
mesh[6].qualifier_ui
mesh[6].descriptor_ui	D005260
mesh[6].is_major_topic	False
mesh[6].qualifier_name
mesh[6].descriptor_name	Female
mesh[7].qualifier_ui
mesh[7].descriptor_ui	D056726
mesh[7].is_major_topic	False
mesh[7].qualifier_name
mesh[7].descriptor_name	Genetic Association Studies
mesh[8].qualifier_ui
mesh[8].descriptor_ui	D006801
mesh[8].is_major_topic	False
mesh[8].qualifier_name
mesh[8].descriptor_name	Humans
mesh[9].qualifier_ui
mesh[9].descriptor_ui	D007564
mesh[9].is_major_topic	False
mesh[9].qualifier_name
mesh[9].descriptor_name	Japan
mesh[10].qualifier_ui
mesh[10].descriptor_ui	D008297
mesh[10].is_major_topic	False
mesh[10].qualifier_name
mesh[10].descriptor_name	Male
mesh[11].qualifier_ui	Q000235
mesh[11].descriptor_ui	D009363
mesh[11].is_major_topic	False
mesh[11].qualifier_name	genetics
mesh[11].descriptor_name	Neoplasm Proteins
mesh[12].qualifier_ui	Q000235
mesh[12].descriptor_ui	D012907
mesh[12].is_major_topic	False
mesh[12].qualifier_name	genetics
mesh[12].descriptor_name	Smoking
mesh[13].qualifier_ui	Q000473
mesh[13].descriptor_ui	D012907
mesh[13].is_major_topic	False
mesh[13].qualifier_name	pathology
mesh[13].descriptor_name	Smoking
mesh[14].qualifier_ui	Q000235
mesh[14].descriptor_ui	D014408
mesh[14].is_major_topic	False
mesh[14].qualifier_name	genetics
mesh[14].descriptor_name	Biomarkers, Tumor
mesh[15].qualifier_ui	Q000235
mesh[15].descriptor_ui	D002289
mesh[15].is_major_topic	False
mesh[15].qualifier_name	genetics
mesh[15].descriptor_name	Carcinoma, Non-Small-Cell Lung
mesh[16].qualifier_ui	Q000473
mesh[16].descriptor_ui	D002289
mesh[16].is_major_topic	False
mesh[16].qualifier_name	pathology
mesh[16].descriptor_name	Carcinoma, Non-Small-Cell Lung
mesh[17].qualifier_ui
mesh[17].descriptor_ui	D002681
mesh[17].is_major_topic	False
mesh[17].qualifier_name
mesh[17].descriptor_name	China
mesh[18].qualifier_ui	Q000235
mesh[18].descriptor_ui	D019941
mesh[18].is_major_topic	False
mesh[18].qualifier_name	genetics
mesh[18].descriptor_name	Cyclin-Dependent Kinase Inhibitor p16
mesh[19].qualifier_ui	Q000235
mesh[19].descriptor_ui	D019175
mesh[19].is_major_topic	False
mesh[19].qualifier_name	genetics
mesh[19].descriptor_name	DNA Methylation
mesh[20].qualifier_ui
mesh[20].descriptor_ui	D005260
mesh[20].is_major_topic	False
mesh[20].qualifier_name
mesh[20].descriptor_name	Female
mesh[21].qualifier_ui
mesh[21].descriptor_ui	D056726
mesh[21].is_major_topic	False
mesh[21].qualifier_name
mesh[21].descriptor_name	Genetic Association Studies
mesh[22].qualifier_ui
mesh[22].descriptor_ui	D006801
mesh[22].is_major_topic	False
mesh[22].qualifier_name
mesh[22].descriptor_name	Humans
mesh[23].qualifier_ui
mesh[23].descriptor_ui	D007564
mesh[23].is_major_topic	False
mesh[23].qualifier_name
mesh[23].descriptor_name	Japan
mesh[24].qualifier_ui
mesh[24].descriptor_ui	D008297
mesh[24].is_major_topic	False
mesh[24].qualifier_name
mesh[24].descriptor_name	Male
mesh[25].qualifier_ui	Q000235
mesh[25].descriptor_ui	D009363
mesh[25].is_major_topic	False
mesh[25].qualifier_name	genetics
mesh[25].descriptor_name	Neoplasm Proteins
mesh[26].qualifier_ui	Q000235
mesh[26].descriptor_ui	D012907
mesh[26].is_major_topic	False
mesh[26].qualifier_name	genetics
mesh[26].descriptor_name	Smoking
mesh[27].qualifier_ui	Q000473
mesh[27].descriptor_ui	D012907
mesh[27].is_major_topic	False
mesh[27].qualifier_name	pathology
mesh[27].descriptor_name	Smoking
type	review
title	Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients
biblio.issue	1
biblio.volume	5
biblio.last_page	8897
biblio.first_page	8897
topics[0].id	https://openalex.org/T10269
topics[0].field.id	https://openalex.org/fields/13
topics[0].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[0].score	0.9994999766349792
topics[0].domain.id	https://openalex.org/domains/1
topics[0].domain.display_name	Life Sciences
topics[0].subfield.id	https://openalex.org/subfields/1312
topics[0].subfield.display_name	Molecular Biology
topics[0].display_name	Epigenetics and DNA Methylation
topics[1].id	https://openalex.org/T11482
topics[1].field.id	https://openalex.org/fields/13
topics[1].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[1].score	0.9850000143051147
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/1312
topics[1].subfield.display_name	Molecular Biology
topics[1].display_name	RNA modifications and cancer
topics[2].id	https://openalex.org/T10515
topics[2].field.id	https://openalex.org/fields/13
topics[2].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[2].score	0.9713000059127808
topics[2].domain.id	https://openalex.org/domains/1
topics[2].domain.display_name	Life Sciences
topics[2].subfield.id	https://openalex.org/subfields/1306
topics[2].subfield.display_name	Cancer Research
topics[2].display_name	Cancer-related molecular mechanisms research
is_xpac	False
apc_list.value	1890
apc_list.currency	EUR
apc_list.value_usd	2190
apc_paid.value	1890
apc_paid.currency	EUR
apc_paid.value_usd	2190
concepts[0].id	https://openalex.org/C190727270
concepts[0].level	4
concepts[0].score	0.829311192035675
concepts[0].wikidata	https://www.wikidata.org/wiki/Q874745
concepts[0].display_name	DNA methylation
concepts[1].id	https://openalex.org/C2776256026
concepts[1].level	2
concepts[1].score	0.8152446746826172
concepts[1].wikidata	https://www.wikidata.org/wiki/Q47912
concepts[1].display_name	Lung cancer
concepts[2].id	https://openalex.org/C2780265364
concepts[2].level	3
concepts[2].score	0.8130626678466797
concepts[2].wikidata	https://www.wikidata.org/wiki/Q5009957
concepts[2].display_name	CDKN2A
concepts[3].id	https://openalex.org/C2780646079
concepts[3].level	5
concepts[3].score	0.7648624181747437
concepts[3].wikidata	https://www.wikidata.org/wiki/Q17928393
concepts[3].display_name	FHIT
concepts[4].id	https://openalex.org/C33288867
concepts[4].level	3
concepts[4].score	0.7347861528396606
concepts[4].wikidata	https://www.wikidata.org/wiki/Q518328
concepts[4].display_name	Methylation
concepts[5].id	https://openalex.org/C143998085
concepts[5].level	1
concepts[5].score	0.5046604871749878
concepts[5].wikidata	https://www.wikidata.org/wiki/Q162555
concepts[5].display_name	Oncology
concepts[6].id	https://openalex.org/C121608353
concepts[6].level	2
concepts[6].score	0.485318124294281
concepts[6].wikidata	https://www.wikidata.org/wiki/Q12078
concepts[6].display_name	Cancer
concepts[7].id	https://openalex.org/C2908647359
concepts[7].level	2
concepts[7].score	0.45196256041526794
concepts[7].wikidata	https://www.wikidata.org/wiki/Q2625603
concepts[7].display_name	Population
concepts[8].id	https://openalex.org/C71924100
concepts[8].level	0
concepts[8].score	0.4330378770828247
concepts[8].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[8].display_name	Medicine
concepts[9].id	https://openalex.org/C60644358
concepts[9].level	1
concepts[9].score	0.41088879108428955
concepts[9].wikidata	https://www.wikidata.org/wiki/Q128570
concepts[9].display_name	Bioinformatics
concepts[10].id	https://openalex.org/C502942594
concepts[10].level	1
concepts[10].score	0.3983739912509918
concepts[10].wikidata	https://www.wikidata.org/wiki/Q3421914
concepts[10].display_name	Cancer research
concepts[11].id	https://openalex.org/C104317684
concepts[11].level	2
concepts[11].score	0.39666736125946045
concepts[11].wikidata	https://www.wikidata.org/wiki/Q7187
concepts[11].display_name	Gene
concepts[12].id	https://openalex.org/C86803240
concepts[12].level	0
concepts[12].score	0.39410167932510376
concepts[12].wikidata	https://www.wikidata.org/wiki/Q420
concepts[12].display_name	Biology
concepts[13].id	https://openalex.org/C126322002
concepts[13].level	1
concepts[13].score	0.3372073769569397
concepts[13].wikidata	https://www.wikidata.org/wiki/Q11180
concepts[13].display_name	Internal medicine
concepts[14].id	https://openalex.org/C54355233
concepts[14].level	1
concepts[14].score	0.28897592425346375
concepts[14].wikidata	https://www.wikidata.org/wiki/Q7162
concepts[14].display_name	Genetics
concepts[15].id	https://openalex.org/C555283112
concepts[15].level	3
concepts[15].score	0.249598890542984
concepts[15].wikidata	https://www.wikidata.org/wiki/Q1637543
concepts[15].display_name	Carcinogenesis
concepts[16].id	https://openalex.org/C150194340
concepts[16].level	3
concepts[16].score	0.17926689982414246
concepts[16].wikidata	https://www.wikidata.org/wiki/Q26972
concepts[16].display_name	Gene expression
concepts[17].id	https://openalex.org/C2778264664
concepts[17].level	4
concepts[17].score	0.14348340034484863
concepts[17].wikidata	https://www.wikidata.org/wiki/Q422445
concepts[17].display_name	Tumor suppressor gene
concepts[18].id	https://openalex.org/C99454951
concepts[18].level	1
concepts[18].score	0.0
concepts[18].wikidata	https://www.wikidata.org/wiki/Q932068
concepts[18].display_name	Environmental health
keywords[0].id	https://openalex.org/keywords/dna-methylation
keywords[0].score	0.829311192035675
keywords[0].display_name	DNA methylation
keywords[1].id	https://openalex.org/keywords/lung-cancer
keywords[1].score	0.8152446746826172
keywords[1].display_name	Lung cancer
keywords[2].id	https://openalex.org/keywords/cdkn2a
keywords[2].score	0.8130626678466797
keywords[2].display_name	CDKN2A
keywords[3].id	https://openalex.org/keywords/fhit
keywords[3].score	0.7648624181747437
keywords[3].display_name	FHIT
keywords[4].id	https://openalex.org/keywords/methylation
keywords[4].score	0.7347861528396606
keywords[4].display_name	Methylation
keywords[5].id	https://openalex.org/keywords/oncology
keywords[5].score	0.5046604871749878
keywords[5].display_name	Oncology
keywords[6].id	https://openalex.org/keywords/cancer
keywords[6].score	0.485318124294281
keywords[6].display_name	Cancer
keywords[7].id	https://openalex.org/keywords/population
keywords[7].score	0.45196256041526794
keywords[7].display_name	Population
keywords[8].id	https://openalex.org/keywords/medicine
keywords[8].score	0.4330378770828247
keywords[8].display_name	Medicine
keywords[9].id	https://openalex.org/keywords/bioinformatics
keywords[9].score	0.41088879108428955
keywords[9].display_name	Bioinformatics
keywords[10].id	https://openalex.org/keywords/cancer-research
keywords[10].score	0.3983739912509918
keywords[10].display_name	Cancer research
keywords[11].id	https://openalex.org/keywords/gene
keywords[11].score	0.39666736125946045
keywords[11].display_name	Gene
keywords[12].id	https://openalex.org/keywords/biology
keywords[12].score	0.39410167932510376
keywords[12].display_name	Biology
keywords[13].id	https://openalex.org/keywords/internal-medicine
keywords[13].score	0.3372073769569397
keywords[13].display_name	Internal medicine
keywords[14].id	https://openalex.org/keywords/genetics
keywords[14].score	0.28897592425346375
keywords[14].display_name	Genetics
keywords[15].id	https://openalex.org/keywords/carcinogenesis
keywords[15].score	0.249598890542984
keywords[15].display_name	Carcinogenesis
keywords[16].id	https://openalex.org/keywords/gene-expression
keywords[16].score	0.17926689982414246
keywords[16].display_name	Gene expression
keywords[17].id	https://openalex.org/keywords/tumor-suppressor-gene
keywords[17].score	0.14348340034484863
keywords[17].display_name	Tumor suppressor gene
language	en
locations[0].id	doi:10.1038/srep08897
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S196734849
locations[0].source.issn	2045-2322
locations[0].source.type	journal
locations[0].source.is_oa	True
locations[0].source.issn_l	2045-2322
locations[0].source.is_core	True
locations[0].source.is_in_doaj	True
locations[0].source.display_name	Scientific Reports
locations[0].source.host_organization	https://openalex.org/P4310319908
locations[0].source.host_organization_name	Nature Portfolio
locations[0].source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
locations[0].source.host_organization_lineage_names	Nature Portfolio, Springer Nature
locations[0].license	cc-by
locations[0].pdf_url	https://www.nature.com/articles/srep08897.pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id	https://openalex.org/licenses/cc-by
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Scientific Reports
locations[0].landing_page_url	https://doi.org/10.1038/srep08897
locations[1].id	pmid:25754026
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	Scientific reports
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/25754026
locations[2].id	pmh:oai:europepmc.org:3326481
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S4306400806
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	Europe PMC (PubMed Central)
locations[2].source.host_organization	https://openalex.org/I1303153112
locations[2].source.host_organization_name	European Bioinformatics Institute
locations[2].source.host_organization_lineage	https://openalex.org/I1303153112
locations[2].license	cc-by
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	Text
locations[2].license_id	https://openalex.org/licenses/cc-by
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name
locations[2].landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/4354004
locations[3].id	pmh:oai:pubmedcentral.nih.gov:4354004
locations[3].is_oa	True
locations[3].source.id	https://openalex.org/S2764455111
locations[3].source.issn
locations[3].source.type	repository
locations[3].source.is_oa	False
locations[3].source.issn_l
locations[3].source.is_core	False
locations[3].source.is_in_doaj	False
locations[3].source.display_name	PubMed Central
locations[3].source.host_organization	https://openalex.org/I1299303238
locations[3].source.host_organization_name	National Institutes of Health
locations[3].source.host_organization_lineage	https://openalex.org/I1299303238
locations[3].license	cc-by
locations[3].pdf_url
locations[3].version	submittedVersion
locations[3].raw_type	Text
locations[3].license_id	https://openalex.org/licenses/cc-by
locations[3].is_accepted	False
locations[3].is_published	False
locations[3].raw_source_name
locations[3].landing_page_url	http://doi.org/10.1038/srep08897
indexed_in	crossref, doaj, pubmed
authorships[0].author.id	https://openalex.org/A5100609501
authorships[0].author.orcid	https://orcid.org/0000-0002-9198-2868
authorships[0].author.display_name	Tao Huang
authorships[0].countries	CN
authorships[0].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[0].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[0].institutions[0].id	https://openalex.org/I109935558
authorships[0].institutions[0].ror	https://ror.org/03et85d35
authorships[0].institutions[0].type	education
authorships[0].institutions[0].lineage	https://openalex.org/I109935558
authorships[0].institutions[0].country_code	CN
authorships[0].institutions[0].display_name	Ningbo University
authorships[0].author_position	first
authorships[0].raw_author_name	Tao Huang
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[1].author.id	https://openalex.org/A5100726391
authorships[1].author.orcid	https://orcid.org/0000-0002-5548-3973
authorships[1].author.display_name	Xiaoying Chen
authorships[1].countries	CN
authorships[1].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[1].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[1].institutions[0].id	https://openalex.org/I109935558
authorships[1].institutions[0].ror	https://ror.org/03et85d35
authorships[1].institutions[0].type	education
authorships[1].institutions[0].lineage	https://openalex.org/I109935558
authorships[1].institutions[0].country_code	CN
authorships[1].institutions[0].display_name	Ningbo University
authorships[1].author_position	middle
authorships[1].raw_author_name	Xiaoying Chen
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[2].author.id	https://openalex.org/A5024310788
authorships[2].author.orcid
authorships[2].author.display_name	Qingxiao Hong
authorships[2].countries	CN
authorships[2].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[2].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[2].institutions[0].id	https://openalex.org/I109935558
authorships[2].institutions[0].ror	https://ror.org/03et85d35
authorships[2].institutions[0].type	education
authorships[2].institutions[0].lineage	https://openalex.org/I109935558
authorships[2].institutions[0].country_code	CN
authorships[2].institutions[0].display_name	Ningbo University
authorships[2].author_position	middle
authorships[2].raw_author_name	Qingxiao Hong
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[3].author.id	https://openalex.org/A5103030133
authorships[3].author.orcid	https://orcid.org/0000-0002-7324-4191
authorships[3].author.display_name	Zaichun Deng
authorships[3].countries	CN
authorships[3].affiliations[0].institution_ids	https://openalex.org/I4210153915
authorships[3].affiliations[0].raw_affiliation_string	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[3].institutions[0].id	https://openalex.org/I4210153915
authorships[3].institutions[0].ror	https://ror.org/045rymn14
authorships[3].institutions[0].type	healthcare
authorships[3].institutions[0].lineage	https://openalex.org/I4210153915
authorships[3].institutions[0].country_code	CN
authorships[3].institutions[0].display_name	Ningbo University Affiliated Hospital
authorships[3].author_position	middle
authorships[3].raw_author_name	Zaichun Deng
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[4].author.id	https://openalex.org/A5033210183
authorships[4].author.orcid	https://orcid.org/0000-0001-6846-4125
authorships[4].author.display_name	Hongying Ma
authorships[4].countries	CN
authorships[4].affiliations[0].institution_ids	https://openalex.org/I4210153915
authorships[4].affiliations[0].raw_affiliation_string	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[4].institutions[0].id	https://openalex.org/I4210153915
authorships[4].institutions[0].ror	https://ror.org/045rymn14
authorships[4].institutions[0].type	healthcare
authorships[4].institutions[0].lineage	https://openalex.org/I4210153915
authorships[4].institutions[0].country_code	CN
authorships[4].institutions[0].display_name	Ningbo University Affiliated Hospital
authorships[4].author_position	middle
authorships[4].raw_author_name	Hongying Ma
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[5].author.id	https://openalex.org/A5011221713
authorships[5].author.orcid	https://orcid.org/0000-0001-6624-9333
authorships[5].author.display_name	Yanfei Xin
authorships[5].countries	CN
authorships[5].affiliations[0].institution_ids	https://openalex.org/I4210130422
authorships[5].affiliations[0].raw_affiliation_string	State Key Laboratory of Safety Evaluation for New Drugs, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang, China
authorships[5].institutions[0].id	https://openalex.org/I4210130422
authorships[5].institutions[0].ror	https://ror.org/03tebsy12
authorships[5].institutions[0].type	education
authorships[5].institutions[0].lineage	https://openalex.org/I4210130422
authorships[5].institutions[0].country_code	CN
authorships[5].institutions[0].display_name	Zhejiang Academy of Medical Sciences
authorships[5].author_position	middle
authorships[5].raw_author_name	Yanfei Xin
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	State Key Laboratory of Safety Evaluation for New Drugs, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang, China
authorships[6].author.id	https://openalex.org/A5102831883
authorships[6].author.orcid	https://orcid.org/0000-0002-0588-2116
authorships[6].author.display_name	Yong Fang
authorships[6].countries	CN
authorships[6].affiliations[0].institution_ids	https://openalex.org/I2802390878, https://openalex.org/I76130692
authorships[6].affiliations[0].raw_affiliation_string	Department of Medical Oncology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, Zhejiang, China
authorships[6].institutions[0].id	https://openalex.org/I2802390878
authorships[6].institutions[0].ror	https://ror.org/00ka6rp58
authorships[6].institutions[0].type	healthcare
authorships[6].institutions[0].lineage	https://openalex.org/I2802390878
authorships[6].institutions[0].country_code	CN
authorships[6].institutions[0].display_name	Sir Run Run Shaw Hospital
authorships[6].institutions[1].id	https://openalex.org/I76130692
authorships[6].institutions[1].ror	https://ror.org/00a2xv884
authorships[6].institutions[1].type	education
authorships[6].institutions[1].lineage	https://openalex.org/I76130692
authorships[6].institutions[1].country_code	CN
authorships[6].institutions[1].display_name	Zhejiang University
authorships[6].author_position	middle
authorships[6].raw_author_name	Yong Fang
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Department of Medical Oncology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, Zhejiang, China
authorships[7].author.id	https://openalex.org/A5007538944
authorships[7].author.orcid
authorships[7].author.display_name	Huadan Ye
authorships[7].countries	CN
authorships[7].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[7].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[7].institutions[0].id	https://openalex.org/I109935558
authorships[7].institutions[0].ror	https://ror.org/03et85d35
authorships[7].institutions[0].type	education
authorships[7].institutions[0].lineage	https://openalex.org/I109935558
authorships[7].institutions[0].country_code	CN
authorships[7].institutions[0].display_name	Ningbo University
authorships[7].author_position	middle
authorships[7].raw_author_name	Huadan Ye
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[8].author.id	https://openalex.org/A5085053186
authorships[8].author.orcid	https://orcid.org/0000-0001-7144-1450
authorships[8].author.display_name	Rujie Wang
authorships[8].countries	CN
authorships[8].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[8].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[8].institutions[0].id	https://openalex.org/I109935558
authorships[8].institutions[0].ror	https://ror.org/03et85d35
authorships[8].institutions[0].type	education
authorships[8].institutions[0].lineage	https://openalex.org/I109935558
authorships[8].institutions[0].country_code	CN
authorships[8].institutions[0].display_name	Ningbo University
authorships[8].author_position	middle
authorships[8].raw_author_name	Rujie Wang
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[9].author.id	https://openalex.org/A5100439596
authorships[9].author.orcid	https://orcid.org/0000-0001-7665-8675
authorships[9].author.display_name	Cheng Zhang
authorships[9].countries	CN
authorships[9].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[9].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[9].institutions[0].id	https://openalex.org/I109935558
authorships[9].institutions[0].ror	https://ror.org/03et85d35
authorships[9].institutions[0].type	education
authorships[9].institutions[0].lineage	https://openalex.org/I109935558
authorships[9].institutions[0].country_code	CN
authorships[9].institutions[0].display_name	Ningbo University
authorships[9].author_position	middle
authorships[9].raw_author_name	Cheng Zhang
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[10].author.id	https://openalex.org/A5100350910
authorships[10].author.orcid	https://orcid.org/0000-0002-4558-8384
authorships[10].author.display_name	Meng Ye
authorships[10].countries	CN
authorships[10].affiliations[0].institution_ids	https://openalex.org/I4210153915
authorships[10].affiliations[0].raw_affiliation_string	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[10].institutions[0].id	https://openalex.org/I4210153915
authorships[10].institutions[0].ror	https://ror.org/045rymn14
authorships[10].institutions[0].type	healthcare
authorships[10].institutions[0].lineage	https://openalex.org/I4210153915
authorships[10].institutions[0].country_code	CN
authorships[10].institutions[0].display_name	Ningbo University Affiliated Hospital
authorships[10].author_position	middle
authorships[10].raw_author_name	Meng Ye
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	The Affiliated Hospital of Ningbo University, Ningbo, 315020, Zhejiang, China
authorships[11].author.id	https://openalex.org/A5021249077
authorships[11].author.orcid	https://orcid.org/0000-0001-7682-2877
authorships[11].author.display_name	Shiwei Duan
authorships[11].countries	CN
authorships[11].affiliations[0].institution_ids	https://openalex.org/I109935558
authorships[11].affiliations[0].raw_affiliation_string	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
authorships[11].institutions[0].id	https://openalex.org/I109935558
authorships[11].institutions[0].ror	https://ror.org/03et85d35
authorships[11].institutions[0].type	education
authorships[11].institutions[0].lineage	https://openalex.org/I109935558
authorships[11].institutions[0].country_code	CN
authorships[11].institutions[0].display_name	Ningbo University
authorships[11].author_position	last
authorships[11].raw_author_name	Shiwei Duan
authorships[11].is_corresponding	False
authorships[11].raw_affiliation_strings	Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, Zhejiang, China
has_content.pdf	True
has_content.grobid_xml	True
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://www.nature.com/articles/srep08897.pdf
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients
has_fulltext	True
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10269
primary_topic.field.id	https://openalex.org/fields/13
primary_topic.field.display_name	Biochemistry, Genetics and Molecular Biology
primary_topic.score	0.9994999766349792
primary_topic.domain.id	https://openalex.org/domains/1
primary_topic.domain.display_name	Life Sciences
primary_topic.subfield.id	https://openalex.org/subfields/1312
primary_topic.subfield.display_name	Molecular Biology
primary_topic.display_name	Epigenetics and DNA Methylation
related_works	https://openalex.org/W1991606148, https://openalex.org/W2384856880, https://openalex.org/W2389510127, https://openalex.org/W2010827483, https://openalex.org/W2384437642, https://openalex.org/W2384299386, https://openalex.org/W2388431263, https://openalex.org/W3029333431, https://openalex.org/W2364035007, https://openalex.org/W1969754992
cited_by_count	70
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	4
counts_by_year[1].year	2024
counts_by_year[1].cited_by_count	2
counts_by_year[2].year	2023
counts_by_year[2].cited_by_count	4
counts_by_year[3].year	2022
counts_by_year[3].cited_by_count	2
counts_by_year[4].year	2021
counts_by_year[4].cited_by_count	3
counts_by_year[5].year	2020
counts_by_year[5].cited_by_count	9
counts_by_year[6].year	2019
counts_by_year[6].cited_by_count	5
counts_by_year[7].year	2018
counts_by_year[7].cited_by_count	12
counts_by_year[8].year	2017
counts_by_year[8].cited_by_count	14
counts_by_year[9].year	2016
counts_by_year[9].cited_by_count	13
counts_by_year[10].year	2015
counts_by_year[10].cited_by_count	2
locations_count	4
best_oa_location.id	doi:10.1038/srep08897
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S196734849
best_oa_location.source.issn	2045-2322
best_oa_location.source.type	journal
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	2045-2322
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	True
best_oa_location.source.display_name	Scientific Reports
best_oa_location.source.host_organization	https://openalex.org/P4310319908
best_oa_location.source.host_organization_name	Nature Portfolio
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
best_oa_location.source.host_organization_lineage_names	Nature Portfolio, Springer Nature
best_oa_location.license	cc-by
best_oa_location.pdf_url	https://www.nature.com/articles/srep08897.pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id	https://openalex.org/licenses/cc-by
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Scientific Reports
best_oa_location.landing_page_url	https://doi.org/10.1038/srep08897
primary_location.id	doi:10.1038/srep08897
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S196734849
primary_location.source.issn	2045-2322
primary_location.source.type	journal
primary_location.source.is_oa	True
primary_location.source.issn_l	2045-2322
primary_location.source.is_core	True
primary_location.source.is_in_doaj	True
primary_location.source.display_name	Scientific Reports
primary_location.source.host_organization	https://openalex.org/P4310319908
primary_location.source.host_organization_name	Nature Portfolio
primary_location.source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
primary_location.source.host_organization_lineage_names	Nature Portfolio, Springer Nature
primary_location.license	cc-by
primary_location.pdf_url	https://www.nature.com/articles/srep08897.pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id	https://openalex.org/licenses/cc-by
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Scientific Reports
primary_location.landing_page_url	https://doi.org/10.1038/srep08897
publication_date	2015-03-10
publication_year	2015
referenced_works	https://openalex.org/W2161167330, https://openalex.org/W2090029719, https://openalex.org/W2165948908, https://openalex.org/W1547463098, https://openalex.org/W2033445993, https://openalex.org/W2099628341, https://openalex.org/W2169256892, https://openalex.org/W2165880441, https://openalex.org/W2084705909, https://openalex.org/W1503277017, https://openalex.org/W1964630765, https://openalex.org/W2136156766, https://openalex.org/W1559060919, https://openalex.org/W7074037533, https://openalex.org/W2060491830, https://openalex.org/W2204334269, https://openalex.org/W2051329166, https://openalex.org/W335520613, https://openalex.org/W2054742531, https://openalex.org/W2150680072, https://openalex.org/W2092671982, https://openalex.org/W2016830527, https://openalex.org/W1966766335, https://openalex.org/W2134442490, https://openalex.org/W2058374133, https://openalex.org/W2109628305, https://openalex.org/W2312460312, https://openalex.org/W2173921146, https://openalex.org/W2153219327, https://openalex.org/W2120878828, https://openalex.org/W2029939247, https://openalex.org/W2169006371, https://openalex.org/W2115105291, https://openalex.org/W2169961966, https://openalex.org/W2038679660, https://openalex.org/W1909768921, https://openalex.org/W1602762875, https://openalex.org/W1983633124, https://openalex.org/W2219978888
referenced_works_count	39
abstract_inverted_index
cited_by_percentile_year.max	100
cited_by_percentile_year.min	94
countries_distinct_count	1
institutions_distinct_count	12
sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.8899999856948853
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.97200674
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True