Metabolome and transcriptome profiling of root chicory provide insights into laticifer development and specialized metabolism Article Swipe
Khabat Vahabi
,
Gerd U. Balcke
,
Johanna C. Hakkert
,
I.M. van der Meer
,
Benedikt Athmer
,
Alain Tissier
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1101/2024.01.02.573856
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1101/2024.01.02.573856
Chicory roots produce inulin, a dietary fiber, as well as large quantities of bitter sesquiterpene lactones (STLs), which have valuable biological activities. In an effort to understand the compartmentalization of metabolism within chicory roots and the molecular basis of the development of laticifers that produce the chicory latex, we performed metabolomics and transcriptomics profiling. GC-MS and LC-MS identified a total of 22 580 features of which 135 were differentially abundant between cell types. Further analysis indicated that the major STLs accumulated primarily in the latex. Gene expression of known STL pathway genes indicates a compartmentalization of the biosynthesis across multiple tissues, with implications regarding the trafficking of pathway intermediates. Phytohormone measurements and gene expression analysis point to a major role for jasmonate signaling in the development and differentiation of laticifers. Furthermore, inulin accumulates mostly outside the laticifers but expression of inulin metabolic genes also point to a complex distribution and trafficking of inulin or inulin precursors across different root compartments. Altogether, the data presented here constitute a unique resource to investigate several biological processes in chicory roots, including laticifer development, STL biosynthesis and transport and inulin biosynthesis regulation. Significance statement A combination of transcriptomics, targeted and untargeted metabolomics of different tissues of chicory roots was generated. These data constitute a resource basis for the investigation of various processes taking place in chicory taproots, including sesquiterpene lactone biosynthesis, laticifer development and inulin biosynthesis and trafficking.
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- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2024.01.02.573856
- https://www.biorxiv.org/content/biorxiv/early/2024/01/02/2024.01.02.573856.full.pdf
- OA Status
- green
- Cited By
- 1
- References
- 89
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4390656835
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4390656835Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/2024.01.02.573856Digital Object Identifier
- Title
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Metabolome and transcriptome profiling of root chicory provide insights into laticifer development and specialized metabolismWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-01-02Full publication date if available
- Authors
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Khabat Vahabi, Gerd U. Balcke, Johanna C. Hakkert, I.M. van der Meer, Benedikt Athmer, Alain TissierList of authors in order
- Landing page
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https://doi.org/10.1101/2024.01.02.573856Publisher landing page
- PDF URL
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https://www.biorxiv.org/content/biorxiv/early/2024/01/02/2024.01.02.573856.full.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
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https://www.biorxiv.org/content/biorxiv/early/2024/01/02/2024.01.02.573856.full.pdfDirect OA link when available
- Concepts
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Inulin, Metabolomics, Transcriptome, Biology, Metabolome, Fructan, Metabolic pathway, Cichorium, Biochemistry, Compartmentalization (fire protection), Computational biology, Gene expression, Metabolism, Gene, Botany, Bioinformatics, Enzyme, SucroseTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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89Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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