Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias Article Swipe

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Ala Taji Heravi , Dmitry Gryaznov , Jason W. Busse , Christof Schönenberger , Belinda von Niederhäusern , L. Hausheer , Manuela Covino , Johannes M. Schwenke , Selina Epp , Alexandra Griessbach , Malena Chiaborelli , Arnav Agarwal , Szimonetta Lohner , Julian Hirt , Stefan Schandelmaier , Simon B Egli , Moshao Amos Makhele , Alain Amstutz , Dominik Mertz , Anette Blümle , Erik von Elm , Ramon Saccilotto , Ayodele Odutayo , Sally Hopewell , Benjamin Speich , Matthias Briel ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1016/j.jclinepi.2025.111822

Less than half of RCT protocols with planned PROs reported them as specified in corresponding published results, suggesting outcome reporting bias, and PRO reporting quality was often deficient. These limitations complicate informed decision-making between patients and health-care providers, as well as the development of evidence-based clinical practice guidelines.

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Outcome (game theory) Meta-analysis Medicine MEDLINE Reporting bias Publication bias Clinical trial Protocol (science) Alternative medicine Internal medicine Pathology Biology Mathematics Biochemistry Mathematical economics

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Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.jclinepi.2025.111822
OA Status: hybrid
Cited By: 1
References: 47
Related Works: 10
OpenAlex ID: https://openalex.org/W4410218088

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DOI: https://doi.org/10.1016/j.jclinepi.2025.111822

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Title: Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias

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Language: en

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Publication year: 2025

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Publication date: 2025-05-09

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Authors: Ala Taji Heravi, Dmitry Gryaznov, Jason W. Busse, Christof Schönenberger, Belinda von Niederhäusern, L. Hausheer, Manuela Covino, Johannes M. Schwenke, Selina Epp, Alexandra Griessbach, Malena Chiaborelli, Arnav Agarwal, Szimonetta Lohner, Julian Hirt, Stefan Schandelmaier, Simon B Egli, Moshao Amos Makhele, Alain Amstutz, Dominik Mertz, Anette Blümle, Erik von Elm, Ramon Saccilotto, Ayodele Odutayo, Sally Hopewell, Benjamin Speich, Matthias Briel

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Landing page: https://doi.org/10.1016/j.jclinepi.2025.111822

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Concepts: Outcome (game theory), Meta-analysis, Medicine, MEDLINE, Reporting bias, Publication bias, Clinical trial, Protocol (science), Alternative medicine, Internal medicine, Pathology, Biology, Mathematics, Biochemistry, Mathematical economics

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Cited by: 1

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