Mimicking Nature in Reshaping the Triterpene Skeleton: Synthesis of a Class of Unnatural Oleanane Derivatives Article Swipe
Edoardo di Biase
,
Ernesto Gargiulo
,
Daniela Imperio
,
Giuseppina Chianese
,
Diego Caprioglio
,
Hawraz Ibrahim M. Amin
,
Orazio Taglialatela‐Scafati
,
Alberto Minassi
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1021/acs.orglett.5c02231
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1021/acs.orglett.5c02231
The possibility of duplicating the efficiency and selectivity of natural processes under laboratory conditions remains a significant challenge for organic chemists. In this letter, we demonstrated that it is possible to introduce pinpoint modifications and to reshape the terpene skeleton of easily available oleananes in a biomimetic fashion. Furthermore, aromatization of the A ring of the triterpene system is reported here for the first time, mimicking what occurs exclusively in nature in sediments.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1021/acs.orglett.5c02231
- OA Status
- hybrid
- Cited By
- 1
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4412138052
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4412138052Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1021/acs.orglett.5c02231Digital Object Identifier
- Title
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Mimicking Nature in Reshaping the Triterpene Skeleton: Synthesis of a Class of Unnatural Oleanane DerivativesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-07-10Full publication date if available
- Authors
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Edoardo di Biase, Ernesto Gargiulo, Daniela Imperio, Giuseppina Chianese, Diego Caprioglio, Hawraz Ibrahim M. Amin, Orazio Taglialatela‐Scafati, Alberto MinassiList of authors in order
- Landing page
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https://doi.org/10.1021/acs.orglett.5c02231Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
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https://doi.org/10.1021/acs.orglett.5c02231Direct OA link when available
- Concepts
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Chemistry, Triterpene, Oleanane, Skeleton (computer programming), Stereochemistry, Terpene, Class (philosophy), Combinatorial chemistry, Artificial intelligence, Pathology, Programming language, Computer science, Medicine, Alternative medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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