Molecular detection of Orientia tsutsugamushi strains circulating in Nagaland Article Swipe
Related Concepts
Orientia tsutsugamushi
Eschar
Scrub typhus
Biology
Virology
Strain (injury)
Homology (biology)
Gene
Microbiology
Veterinary medicine
Medicine
Genetics
Pathology
Anatomy
Siraj Ahmed Khan
,
Jahnabi Saikia
,
Trishna Bora
,
Vinotsole Khamo
,
Manju Rahi
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.ijmmb.2022.04.006
· OA: W4229065585
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.ijmmb.2022.04.006
· OA: W4229065585
The antigenic heterogeneity of Orientia in India is still unknown in many disease endemic areas. The present study aims to characterize the strains of O. tsutsugamushi circulating in Nagaland, Northeast India. Two patients clinically diagnosed with ST and hospitalized in Mon district hospital, Nagaland were identified from whom eschar tissues were collected. Both patients demonstrated antibodies against O. tsutsugamushi along with positive PCR amplification for 56 kDa gene. The prototype strain TA763 shared 90.4% homology with the sequences. Both the sequences formed a distinctive cluster demonstrating 100% similarity with strains identified from Thailand, Vietnam, China and southern parts of India.
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