MP65-02 QUANTIFYING GLANS WIDTH CHANGES WITH AND WITHOUT TESTOSTERONE IN PATIENTS UNDERGOING HYPOSPADIAS REPAIR Article Swipe
Sameer Mittal
,
Sarah Christianson
,
Nathan Hyacinthe
,
C. B. Tan
,
Dana Weiß
,
Jason Van Batavia
,
Aseem R. Shukla
,
Thomas F. Kolon
,
Arun K. Srinivasan
,
Douglas A. Canning
,
Mark R. Zaontz
,
Christopher Long
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1097/ju.0000000000000940.01
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1097/ju.0000000000000940.01
You have accessJournal of UrologyPediatrics: Hypospadias and Penile Surgery (MP65)1 Apr 2020MP65-02 QUANTIFYING GLANS WIDTH CHANGES WITH AND WITHOUT TESTOSTERONE IN PATIENTS UNDERGOING HYPOSPADIAS REPAIR Sameer Mittal, Sarah Christianson*, Nathan Hyacinthe, Connie Tan, Dana Weiss, Jason Van Batavia, Aseem Shukla, Thomas Kolon, Arun Srinivasan, Douglas Canning, Mark Zaontz, and Christopher Long Sameer MittalSameer Mittal More articles by this author , Sarah Christianson*Sarah Christianson* More articles by this author , Nathan HyacintheNathan Hyacinthe More articles by this author , Connie TanConnie Tan More articles by this author , Dana WeissDana Weiss More articles by this author , Jason Van BataviaJason Van Batavia More articles by this author , Aseem ShuklaAseem Shukla More articles by this author , Thomas KolonThomas Kolon More articles by this author , Arun SrinivasanArun Srinivasan More articles by this author , Douglas CanningDouglas Canning More articles by this author , Mark ZaontzMark Zaontz More articles by this author , and Christopher LongChristopher Long More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000940.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Testosterone (T) use prior to hypospadias surgery remains controversial. Understanding its effects on glans size is essential to understanding its efficacy. Our hypothesis was that T preoperatively increases GW measured at surgery. Our goal was to quantify the change with and without T prior to surgery. METHODS: Our database was queried to identify patients who underwent hypospadias surgery from 2015-2019, in which data for T administration and glans measurements were available. Descriptive, nonparametric and categorical statistics were performed as indicated. RESULTS: 648 patients were eligible for analysis. Median age at surgery was 0.9 years (IQR 0.6-1.7). 200/648 (31.3%) patients received T. The median GW at surgery was 15mm (IQR 13-17). When comparing patients who had T administered to those that did not, we found a significant difference in GW at surgery (16mm vs 14mm, p<0.001) [Table 1]. The median change in GW preoperatively to surgery was 4mm for those receiving T vs -1mm for those not receiving T (p<0.001). We observed a trend toward significance of increased administration of T for first- and second-stage repairs (p=0.062) and concordantly a higher proportion of proximal hypospadias patients received T (p=0.003). We identified a greater change in GW from preoperative to intraoperative measurements in patients who received two doses of T vs one dose (4mm vs 2mm, p<0.001) [Table 2]. A histogram plot revealed the distribution of GW change at surgery (Figure 1). CONCLUSIONS: In our large, prospectively collected cohort of patients undergoing hypospadias surgery, we were able to quantitate the change in GW from preoperative testosterone. Two doses of testosterone resulted in a significant increase in glans width vs one dose. Source of Funding: NA © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e972-e973 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sameer Mittal More articles by this author Sarah Christianson* More articles by this author Nathan Hyacinthe More articles by this author Connie Tan More articles by this author Dana Weiss More articles by this author Jason Van Batavia More articles by this author Aseem Shukla More articles by this author Thomas Kolon More articles by this author Arun Srinivasan More articles by this author Douglas Canning More articles by this author Mark Zaontz More articles by this author Christopher Long More articles by this author Expand All Advertisement PDF downloadLoading ...
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1097/ju.0000000000000940.01
- https://www.auajournals.org/doi/pdf/10.1097/JU.0000000000000940.01
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https://openalex.org/W3022472043Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1097/ju.0000000000000940.01Digital Object Identifier
- Title
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MP65-02 QUANTIFYING GLANS WIDTH CHANGES WITH AND WITHOUT TESTOSTERONE IN PATIENTS UNDERGOING HYPOSPADIAS REPAIRWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
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2020Year of publication
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2020-04-01Full publication date if available
- Authors
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Sameer Mittal, Sarah Christianson, Nathan Hyacinthe, C. B. Tan, Dana Weiß, Jason Van Batavia, Aseem R. Shukla, Thomas F. Kolon, Arun K. Srinivasan, Douglas A. Canning, Mark R. Zaontz, Christopher LongList of authors in order
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https://doi.org/10.1097/ju.0000000000000940.01Publisher landing page
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https://www.auajournals.org/doi/pdf/10.1097/JU.0000000000000940.01Direct link to full text PDF
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://www.auajournals.org/doi/pdf/10.1097/JU.0000000000000940.01Direct OA link when available
- Concepts
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Hypospadias, Medicine, Glans, Testosterone (patch), Glans penis, Gynecology, General surgery, Surgery, Penis, Internal medicineTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.(IQR | 270, 284 |
| abstract_inverted_index.-1mm | 328 |
| abstract_inverted_index.15mm | 283 |
| abstract_inverted_index.2020 | 450, 469 |
| abstract_inverted_index.2mm, | 389 |
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| abstract_inverted_index.Dana | 33, 87, 507 |
| abstract_inverted_index.Long | 50, 155, 558 |
| abstract_inverted_index.Mark | 46, 143, 550 |
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| abstract_inverted_index.that | 200, 295 |
| abstract_inverted_index.this | 57, 66, 75, 84, 93, 104, 113, 122, 131, 140, 149, 159, 484, 491, 498, 505, 512, 520, 527, 534, 541, 548, 555, 562 |
| abstract_inverted_index.were | 245, 252, 259, 419 |
| abstract_inverted_index.with | 215 |
| abstract_inverted_index.(16mm | 307 |
| abstract_inverted_index.14mm, | 309 |
| abstract_inverted_index.Aseem | 38, 107, 522 |
| abstract_inverted_index.GLANS | 13 |
| abstract_inverted_index.Jason | 35, 96, 514 |
| abstract_inverted_index.Kolon | 118, 530 |
| abstract_inverted_index.Sarah | 27, 60, 486 |
| abstract_inverted_index.WIDTH | 14 |
| abstract_inverted_index.Weiss | 89, 508 |
| abstract_inverted_index.dose. | 444 |
| abstract_inverted_index.doses | 381, 431 |
| abstract_inverted_index.found | 299 |
| abstract_inverted_index.glans | 189, 243, 440 |
| abstract_inverted_index.prior | 179, 219 |
| abstract_inverted_index.those | 294, 324, 330 |
| abstract_inverted_index.trend | 338 |
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| abstract_inverted_index.Expand | 564 |
| abstract_inverted_index.Kolon, | 41 |
| abstract_inverted_index.Median | 263 |
| abstract_inverted_index.Mittal | 53, 480 |
| abstract_inverted_index.Nathan | 29, 69, 493 |
| abstract_inverted_index.Penile | 7 |
| abstract_inverted_index.REPAIR | 24 |
| abstract_inverted_index.Sameer | 25, 51, 479 |
| abstract_inverted_index.Shukla | 109, 523 |
| abstract_inverted_index.Source | 445 |
| abstract_inverted_index.Thomas | 40, 116, 529 |
| abstract_inverted_index.Volume | 459 |
| abstract_inverted_index.Weiss, | 34 |
| abstract_inverted_index.Zaontz | 145, 551 |
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| abstract_inverted_index.cohort | 412 |
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| abstract_inverted_index.large, | 409 |
| abstract_inverted_index.median | 278, 314 |
| abstract_inverted_index.toward | 339 |
| abstract_inverted_index.(31.3%) | 273 |
| abstract_inverted_index.(Figure | 404 |
| abstract_inverted_index.(MP65)1 | 9 |
| abstract_inverted_index.13-17). | 285 |
| abstract_inverted_index.200/648 | 272 |
| abstract_inverted_index.Batavia | 100, 516 |
| abstract_inverted_index.CHANGES | 15 |
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| abstract_inverted_index.Douglas | 44, 134, 543 |
| abstract_inverted_index.Mittal, | 26 |
| abstract_inverted_index.Shukla, | 39 |
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| abstract_inverted_index.greater | 367 |
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| abstract_inverted_index.remains | 183 |
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| abstract_inverted_index.without | 217 |
| abstract_inverted_index.203Issue | 460 |
| abstract_inverted_index.Abstract | 172 |
| abstract_inverted_index.American | 452, 471 |
| abstract_inverted_index.Batavia, | 37 |
| abstract_inverted_index.Canning, | 45 |
| abstract_inverted_index.Funding: | 447 |
| abstract_inverted_index.METHODS: | 222 |
| abstract_inverted_index.PATIENTS | 21 |
| abstract_inverted_index.RESULTS: | 256 |
| abstract_inverted_index.ToolsAdd | 165 |
| abstract_inverted_index.articles | 55, 64, 73, 82, 91, 102, 111, 120, 129, 138, 147, 157, 482, 489, 496, 503, 510, 518, 525, 532, 539, 546, 553, 560 |
| abstract_inverted_index.database | 224 |
| abstract_inverted_index.eligible | 260 |
| abstract_inverted_index.identify | 228 |
| abstract_inverted_index.increase | 438 |
| abstract_inverted_index.measured | 205 |
| abstract_inverted_index.observed | 336 |
| abstract_inverted_index.p<0.001) | 310, 390 |
| abstract_inverted_index.patients | 229, 258, 274, 288, 360, 377, 414 |
| abstract_inverted_index.proximal | 358 |
| abstract_inverted_index.quantify | 212 |
| abstract_inverted_index.received | 275, 361, 379 |
| abstract_inverted_index.resulted | 434 |
| abstract_inverted_index.revealed | 396 |
| abstract_inverted_index.surgery, | 417 |
| abstract_inverted_index.surgery. | 207, 221 |
| abstract_inverted_index.(p=0.062) | 351 |
| abstract_inverted_index.0.6-1.7). | 271 |
| abstract_inverted_index.2020Page: | 463 |
| abstract_inverted_index.Copyright | 466 |
| abstract_inverted_index.Education | 455, 474 |
| abstract_inverted_index.Hyacinthe | 71, 494 |
| abstract_inverted_index.Research, | 457, 476 |
| abstract_inverted_index.TanConnie | 79 |
| abstract_inverted_index.WeissDana | 88 |
| abstract_inverted_index.analysis. | 262 |
| abstract_inverted_index.collected | 411 |
| abstract_inverted_index.comparing | 287 |
| abstract_inverted_index.e972-e973 | 464 |
| abstract_inverted_index.efficacy. | 196 |
| abstract_inverted_index.essential | 192 |
| abstract_inverted_index.histogram | 394 |
| abstract_inverted_index.increased | 342 |
| abstract_inverted_index.increases | 203 |
| abstract_inverted_index.performed | 253 |
| abstract_inverted_index.receiving | 325, 332 |
| abstract_inverted_index.underwent | 231 |
| abstract_inverted_index.(p<0.001). | 334 |
| abstract_inverted_index.(p=0.003). | 363 |
| abstract_inverted_index.2015-2019, | 235 |
| abstract_inverted_index.Hyacinthe, | 30 |
| abstract_inverted_index.OBJECTIVE: | 175 |
| abstract_inverted_index.Srinivasan | 127, 537 |
| abstract_inverted_index.Supplement | 461 |
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| abstract_inverted_index.Urological | 453, 472 |
| abstract_inverted_index.ZaontzMark | 144 |
| abstract_inverted_index.available. | 246 |
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| abstract_inverted_index.indicated. | 255 |
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| abstract_inverted_index.QUANTIFYING | 12 |
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| abstract_inverted_index.second-stage | 349 |
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| abstract_inverted_index.testosterone | 433 |
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