MtOrt: An empirical mitochondrial amino acid substitution model for evolutionary studies of Orthoptera insects Article Swipe
YOU?
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· 2020
· Open Access
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· DOI: https://doi.org/10.21203/rs.2.20989/v2
Background Amino acid substitution models play an important role in inferring phylogenies from mitochondrial proteins. Although different amino acid substitution models have been proposed, only a few were estimated from mitochondrial protein sequences for specific taxa such as the mtArt model for Arthropoda. The increasing of mitochondrial genome data from broad Orthoptera taxa provides an opportunity to estimate the Orthoptera-specific mitochondrial amino acid empirical model. Results We sequenced complete mitochondrial genomes of 54 Orthoptera species, and then estimated an amino acid substitution model (named mtOrt) by maximum likelihood method based on the 283 complete mitochondrial genomes available currently. The results indicated that there are obvious differences between mtOrt and the existing model, and the new model can better fit the Orthoptera mitochondrial protein datasets. Moreover, topologies of trees constructed using mtOrt and existing models are frequently different. MtOrt does indeed have an impact on likelihood improvement as well as tree topologies. The comparisons between the topologies of trees constructed using mtOrt and existing models show that the new model outperforms the existing models in inferring phylogenies from Orthoptera mitochondrial protein data. Conclusions The new mitochondrial amino acid substitution model of Orthoptera shows obvious differences from the existing models, and outperforms the existing models in inferring phylogenies from Orthoptera mitochondrial protein sequences.
Related Topics
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.2.20989/v2
- https://www.researchsquare.com/article/rs-11587/v2.pdf?c=1631847144000
- OA Status
- gold
- References
- 44
- Related Works
- 10
- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4248231632Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21203/rs.2.20989/v2Digital Object Identifier
- Title
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MtOrt: An empirical mitochondrial amino acid substitution model for evolutionary studies of Orthoptera insectsWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-04-06Full publication date if available
- Authors
-
Huihui Chang, Yimeng Nie, Nan Zhang, Xue Zhang, Huimin Sun, Ying Mao, Zhongying Qiu, Yuan HuangList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.2.20989/v2Publisher landing page
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https://www.researchsquare.com/article/rs-11587/v2.pdf?c=1631847144000Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
-
https://www.researchsquare.com/article/rs-11587/v2.pdf?c=1631847144000Direct OA link when available
- Concepts
-
Orthoptera, Substitution (logic), Amino acid substitution, Amino acid, Biology, Zoology, Biochemistry, Computer science, Mutation, Gene, Programming languageTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
- References (count)
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44Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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