MULocDeep web service for protein localization prediction and visualization at subcellular and suborganellar levels Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.1093/nar/gkad374
Predicting protein localization and understanding its mechanisms are critical in biology and pathology. In this context, we propose a new web application of MULocDeep with improved performance, result interpretation, and visualization. By transferring the original model into species-specific models, MULocDeep achieved competitive prediction performance at the subcellular level against other state-of-the-art methods. It uniquely provides a comprehensive localization prediction at the suborganellar level. Besides prediction, our web service quantifies the contribution of single amino acids to localization for individual proteins; for a group of proteins, common motifs or potential targeting-related regions can be derived. Furthermore, the visualizations of targeting mechanism analyses can be downloaded for publication-ready figures. The MULocDeep web service is available at https://www.mu-loc.org/.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/nar/gkad374
- https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad374/50309920/gkad374.pdf
- OA Status
- gold
- Cited By
- 33
- References
- 26
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4376503900
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4376503900Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/nar/gkad374Digital Object Identifier
- Title
-
MULocDeep web service for protein localization prediction and visualization at subcellular and suborganellar levelsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-05-13Full publication date if available
- Authors
-
Yuexu Jiang, Lei Jiang, Chopparapu Sai Akhil, Duolin Wang, Ziyang Zhang, Weinan Zhang, Dong XuList of authors in order
- Landing page
-
https://doi.org/10.1093/nar/gkad374Publisher landing page
- PDF URL
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https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad374/50309920/gkad374.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad374/50309920/gkad374.pdfDirect OA link when available
- Concepts
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Biology, Visualization, Context (archaeology), Computational biology, Web service, Service (business), Subcellular localization, Protein subcellular localization prediction, Bioinformatics, Computer science, Data mining, World Wide Web, Genetics, Paleontology, Economy, Economics, Gene, CytoplasmTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
33Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 19, 2024: 12, 2023: 2Per-year citation counts (last 5 years)
- References (count)
-
26Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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