Multi working mode SPR chip laboratory for high refractive index detection Article Swipe

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Zhuo Ren , Chunlan Liu , Yong Wei , Chunbiao Liu , Chen Shi , Xingkai Wang , Yixiong Tang , Rui Wang , Zhihai Liu ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1364/oe.493337

The Fiber SPR chip laboratory has become a popular choice in biochemical detection. To meet the needs of different kinds of analytes for the detection range and number of channels of the chip, we proposed a multi-mode SPR chip laboratory based on microstructure fiber in this paper. The chip laboratory was integrated with microfluidic devices made from PDMS and detection units made of bias three-core fiber and dumbbell fiber. By injecting light into different cores of a bias three-core fiber, different detection areas of dumbbell fiber can be selected, enabling the chip laboratory to enter high refractive index detection, multi-channel detection and other working modes. In the high refractive index detection mode, the chip can detect liquid samples with a refractive index range of 1.571-1.595. In multi-channel detection mode, the chip can achieve dual parameter detection of glucose and GHK-Cu, with sensitivities of 4.16 nm/(mg/mL) and 9.729 nm/(mg/mL), respectively. Additionally, the chip can switch to temperature compensation mode. The proposed multi working mode SPR chip laboratory, based on micro structured fiber, offers a new approach for the development of portable testing equipment that can detect multiple analytes and meet multiple requirements.

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$Refractive Index$

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Chip Materials science Optical fiber Refractive index Optics Fiber Lab-on-a-chip Single-mode optical fiber Optoelectronics Microfluidics Computer science Nanotechnology Telecommunications Physics Composite material

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Type: article
Language: en
Landing Page: https://doi.org/10.1364/oe.493337
OA Status: gold
Cited By: 1
References: 22
Related Works: 10
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DOI: https://doi.org/10.1364/oe.493337

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Title: Multi working mode SPR chip laboratory for high refractive index detection

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Language: en

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Publication year: 2023

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Publication date: 2023-05-31

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Authors: Zhuo Ren, Chunlan Liu, Yong Wei, Chunbiao Liu, Chen Shi, Xingkai Wang, Yixiong Tang, Rui Wang, Zhihai Liu

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Landing page: https://doi.org/10.1364/oe.493337

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Concepts: Chip, Materials science, Optical fiber, Refractive index, Optics, Fiber, Lab-on-a-chip, Single-mode optical fiber, Optoelectronics, Microfluidics, Computer science, Nanotechnology, Telecommunications, Physics, Composite material

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Cited by: 1

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