Journal of Regenerative Science • Vol 1 • No 1
Multilineage-differentiating Stress-enduring (MUSE) Cells in Orthobiologics: Are they the Future?
January 2021 • Eduard Alentorn‐Geli, Patricia Laiz, Alfred Ferré‐Aniorte, Roberto Seijas, David Barastegui, Pedro Álvarez‐Díaz, Xavier Cuscó, Cristina Sánchez, Luís…
Multilineage-differentiating stress-enduring (MUSE) cells are non-tumorigenic pluripotent stem cells with endogenous reparative properties. These cells have a very powerful ability to adapt to global environment changes and are thus stress-tolerant cells. Interestingly, MUSE cells can differentiate into cells representative of all three germ layers. There has been a number of studies demonstrating its powerful regenerative power in several disorders: type-1 diabetes mellitus, myocardial infarction, stroke, glomeru…