Multisite microLED optrode array for neural interfacing Article Swipe
Niall McAlinden
,
Yunzhou Cheng
,
Robert Scharf
,
Enyuan Xie
,
Erdan Gu
,
Christopher F. Reiche
,
Rohit Sharma
,
Prashant Tathireddy
,
Prashant Tathireddy
,
Loren Rieth
,
Steve Blair
,
Keith Mathieson
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1117/1.nph.6.3.035010
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1117/1.nph.6.3.035010
We present an electrically addressable optrode array capable of delivering light to 181 sites in the brain, each providing sufficient light to optogenetically excite thousands of neurons in vivo, developed with the aim to allow behavioral studies in large mammals. The device is a glass microneedle array directly integrated with a custom fabricated microLED device, which delivers light to 100 needle tips and 81 interstitial surface sites, giving two-level optogenetic excitation of neurons in vivo. Light delivery and thermal properties are evaluated, with the device capable of peak irradiances per needle site. The device consists of an array of 181 microLEDs, fabricated on a -thick GaN-on-sapphire wafer, coupled to a glass needle array on a thick backplane. A pinhole layer is patterned on the sapphire side of the microLED array to reduce stray light. Future designs are explored through optical and thermal modeling and benchmarked against the current device.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1117/1.nph.6.3.035010
- https://www.spiedigitallibrary.org/journals/neurophotonics/volume-6/issue-3/035010/Multisite-microLED-optrode-array-for-neural-interfacing/10.1117/1.NPh.6.3.035010.pdf
- OA Status
- gold
- Cited By
- 62
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2970359674
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2970359674Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1117/1.nph.6.3.035010Digital Object Identifier
- Title
-
Multisite microLED optrode array for neural interfacingWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-08-28Full publication date if available
- Authors
-
Niall McAlinden, Yunzhou Cheng, Robert Scharf, Enyuan Xie, Erdan Gu, Christopher F. Reiche, Rohit Sharma, Prashant Tathireddy, Prashant Tathireddy, Loren Rieth, Steve Blair, Keith MathiesonList of authors in order
- Landing page
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https://doi.org/10.1117/1.nph.6.3.035010Publisher landing page
- PDF URL
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https://www.spiedigitallibrary.org/journals/neurophotonics/volume-6/issue-3/035010/Multisite-microLED-optrode-array-for-neural-interfacing/10.1117/1.NPh.6.3.035010.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.spiedigitallibrary.org/journals/neurophotonics/volume-6/issue-3/035010/Multisite-microLED-optrode-array-for-neural-interfacing/10.1117/1.NPh.6.3.035010.pdfDirect OA link when available
- Concepts
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Interfacing, Optode, Computer science, Artificial intelligence, Computer hardware, Physics, Optics, FluorescenceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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62Total citation count in OpenAlex
- Citations by year (recent)
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2025: 7, 2024: 9, 2023: 11, 2022: 13, 2021: 12Per-year citation counts (last 5 years)
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46Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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