Myasthenia gravis: Anaesthetic implications and considerations-a report of two cases Article Swipe
Jatin Lal
,
Teena Bansal
·
YOU?
·
· 2016
· Open Access
·
· DOI: https://doi.org/10.7197/cmj.v38i3.5000146050
YOU?
·
· 2016
· Open Access
·
· DOI: https://doi.org/10.7197/cmj.v38i3.5000146050
SUMMARYMyasthenia gravis is an autoimmune disease characterized by weakness and fatigueability of skeletal muscles with improvement following rest. Perioperative management of such a patient poses a significant challenge to the anaesthesiologist, because it affects the neuromuscular junction. Also, the association of myasthenia gravis with other autoimmune disorders is well known. Preoperative evaluation of the patient includes review of the severity of the patient’s disease and the treatment regimen. Optimisation of the condition of the myasthenic patient can markedly decrease the risk of surgery and improve the outcome. Anaesthetic management must be accomplished with the minimal applicable dose of the anaesthetic agents. Because of the unpredictable response to succinylcholine and the marked sensitivity to non depolarizing muscle relaxants, muscle relaxants should be avoided. All patients should be closely monitored postoperatively in the post anaesthesia care unit or surgical intensive care unit, where respiratory support can be immediately reinstituted.Keywords: Myasthenia gravis, anaesthetic implications, anaesthetic management ÖZETMyastenya gravis iskelet kaslarında, dinlenmeyle düzelen zayıflık ve yorgunlukla karakterize otoimmün bir hastalıktır. Böyle bir hastanın perioperatif yönetiminde anesteziyolojistin önemli bir etkisi vardır. Çünkü hastalık nöromuskuler kavşağı etkilemektedir. Aynı zamanda myastenia gravisin diğer otoimmün hastalıklar birlikteliği iyi bilinmektedir. Hastanın preoperatif değerlendirmesi hastalığının şiddetinin gözden geçirilmesi ve tedavi rejimini kapsar. Myasteniya hastasının durumunun optimizasyonu cerrahi riskini anlamlı derecede azaltır ve sonuçlarını iyileştirir. Anestezi uygulaması, anestezik ajanın minimal uygulama dozuyla yapılmalıdır. Süksinil koline karşı öngörülemeyen yanıt ve nondepolarizan kas gevşeticilerine belirgin hassasiyet olabileceği için, kas gevşeticilerden sakınılmalıdır. Tüm hastalar postanestezi ünitesinde ya da cerrahi yoğun bakımda respiratuar desteği hemen sağlayabilecek şekilde yakından monitörüze edilmelidir.Anahtar sözcükler: Myastenya gravis, anestezi müdahalesi, anestezi yönetimi
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.7197/cmj.v38i3.5000146050
- http://dergipark.gov.tr/download/article-file/224653
- OA Status
- bronze
- Cited By
- 1
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- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W2528951242Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.7197/cmj.v38i3.5000146050Digital Object Identifier
- Title
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Myasthenia gravis: Anaesthetic implications and considerations-a report of two casesWork title
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articleOpenAlex work type
- Language
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enPrimary language
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2016Year of publication
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2016-09-26Full publication date if available
- Authors
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Jatin Lal, Teena BansalList of authors in order
- Landing page
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https://doi.org/10.7197/cmj.v38i3.5000146050Publisher landing page
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https://dergipark.gov.tr/download/article-file/224653Direct link to full text PDF
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://dergipark.gov.tr/download/article-file/224653Direct OA link when available
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Medicine, Myasthenia gravis, Gynecology, ImmunologyTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2018: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.includes | 55 |
| abstract_inverted_index.markedly | 77 |
| abstract_inverted_index.outcome. | 86 |
| abstract_inverted_index.patients | 123 |
| abstract_inverted_index.regimen. | 67 |
| abstract_inverted_index.rejimini | 200 |
| abstract_inverted_index.response | 105 |
| abstract_inverted_index.severity | 59 |
| abstract_inverted_index.skeletal | 12 |
| abstract_inverted_index.surgical | 136 |
| abstract_inverted_index.uygulama | 219 |
| abstract_inverted_index.vardır. | 175 |
| abstract_inverted_index.weakness | 8 |
| abstract_inverted_index.Çünkü | 176 |
| abstract_inverted_index.şekilde | 251 |
| abstract_inverted_index.Hastanın | 191 |
| abstract_inverted_index.Myastenya | 256 |
| abstract_inverted_index.Süksinil | 222 |
| abstract_inverted_index.anestezik | 216 |
| abstract_inverted_index.challenge | 27 |
| abstract_inverted_index.condition | 71 |
| abstract_inverted_index.disorders | 46 |
| abstract_inverted_index.durumunun | 204 |
| abstract_inverted_index.following | 16 |
| abstract_inverted_index.hastalık | 177 |
| abstract_inverted_index.hastanın | 168 |
| abstract_inverted_index.intensive | 137 |
| abstract_inverted_index.junction. | 36 |
| abstract_inverted_index.monitored | 127 |
| abstract_inverted_index.myastenia | 183 |
| abstract_inverted_index.otoimmün | 163, 186 |
| abstract_inverted_index.relaxants | 118 |
| abstract_inverted_index.treatment | 66 |
| abstract_inverted_index.yakından | 252 |
| abstract_inverted_index.yönetimi | 261 |
| abstract_inverted_index.Myasteniya | 202 |
| abstract_inverted_index.Myasthenia | 147 |
| abstract_inverted_index.applicable | 95 |
| abstract_inverted_index.autoimmune | 4, 45 |
| abstract_inverted_index.evaluation | 51 |
| abstract_inverted_index.hassasiyet | 232 |
| abstract_inverted_index.kavşağı | 179 |
| abstract_inverted_index.management | 19, 88, 152 |
| abstract_inverted_index.myasthenia | 41 |
| abstract_inverted_index.myasthenic | 74 |
| abstract_inverted_index.relaxants, | 116 |
| abstract_inverted_index.zayıflık | 159 |
| abstract_inverted_index.Anaesthetic | 87 |
| abstract_inverted_index.anaesthesia | 132 |
| abstract_inverted_index.anaesthetic | 99, 149, 151 |
| abstract_inverted_index.association | 39 |
| abstract_inverted_index.dinlenmeyle | 157 |
| abstract_inverted_index.immediately | 145 |
| abstract_inverted_index.improvement | 15 |
| abstract_inverted_index.karakterize | 162 |
| abstract_inverted_index.patient’s | 62 |
| abstract_inverted_index.preoperatif | 192 |
| abstract_inverted_index.respiratory | 141 |
| abstract_inverted_index.respiratuar | 247 |
| abstract_inverted_index.sensitivity | 111 |
| abstract_inverted_index.significant | 26 |
| abstract_inverted_index.yorgunlukla | 161 |
| abstract_inverted_index.ünitesinde | 241 |
| abstract_inverted_index.şiddetinin | 195 |
| abstract_inverted_index.Optimisation | 68 |
| abstract_inverted_index.Preoperative | 50 |
| abstract_inverted_index.accomplished | 91 |
| abstract_inverted_index.depolarizing | 114 |
| abstract_inverted_index.geçirilmesi | 197 |
| abstract_inverted_index.hastalıklar | 187 |
| abstract_inverted_index.hastasının | 203 |
| abstract_inverted_index.kaslarında, | 156 |
| abstract_inverted_index.monitörüze | 253 |
| abstract_inverted_index.müdahalesi, | 259 |
| abstract_inverted_index.olabileceği | 233 |
| abstract_inverted_index.perioperatif | 169 |
| abstract_inverted_index.postanestezi | 240 |
| abstract_inverted_index.sözcükler: | 255 |
| abstract_inverted_index.uygulaması, | 215 |
| abstract_inverted_index.yönetiminde | 170 |
| abstract_inverted_index.Perioperative | 18 |
| abstract_inverted_index.birlikteliği | 188 |
| abstract_inverted_index.characterized | 6 |
| abstract_inverted_index.implications, | 150 |
| abstract_inverted_index.iyileştirir. | 213 |
| abstract_inverted_index.neuromuscular | 35 |
| abstract_inverted_index.nöromuskuler | 178 |
| abstract_inverted_index.optimizasyonu | 205 |
| abstract_inverted_index.unpredictable | 104 |
| abstract_inverted_index.bilinmektedir. | 190 |
| abstract_inverted_index.fatigueability | 10 |
| abstract_inverted_index.hastalıktır. | 165 |
| abstract_inverted_index.nondepolarizan | 228 |
| abstract_inverted_index.sonuçlarını | 212 |
| abstract_inverted_index.ÖZETMyastenya | 153 |
| abstract_inverted_index.etkilemektedir. | 180 |
| abstract_inverted_index.postoperatively | 128 |
| abstract_inverted_index.sağlayabilecek | 250 |
| abstract_inverted_index.succinylcholine | 107 |
| abstract_inverted_index.değerlendirmesi | 193 |
| abstract_inverted_index.gevşeticilerden | 236 |
| abstract_inverted_index.gevşeticilerine | 230 |
| abstract_inverted_index.hastalığının | 194 |
| abstract_inverted_index.yapılmalıdır. | 221 |
| abstract_inverted_index.öngörülemeyen | 225 |
| abstract_inverted_index.SUMMARYMyasthenia | 0 |
| abstract_inverted_index.anaesthesiologist, | 30 |
| abstract_inverted_index.anesteziyolojistin | 171 |
| abstract_inverted_index.edilmelidir.Anahtar | 254 |
| abstract_inverted_index.sakınılmalıdır. | 237 |
| abstract_inverted_index.reinstituted.Keywords: | 146 |
| cited_by_percentile_year.max | 94 |
| cited_by_percentile_year.min | 90 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 2 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.47999998927116394 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.64554612 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |