MYCBP expression pattern and mutant allele. Article Swipe
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· 2025
· Open Access
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· DOI: https://doi.org/10.1371/journal.pgen.1011792.g001
(A) Schematic illustration of Drosophila ovary and germarium. Each female has a pair of ovaries, each consisting of 12-16 ovarioles (cyan). The germarium (outlined in magenta) is located at the anterior tip of each ovariole and contains both germ cells and somatic cells. Germ cells include germline stem cells (GSCs), cystoblasts, cysts, and differentiating oocytes. Somatic cells include terminal filament (TF) cells, cap cells (CCc), escort cells (ECs), and follicle cells (FCs). GSCs and cystoblasts have spherical, unbranched spectrosomes, whereas cysts posesss branched fusomes. The distinct regions of the germarium—1, 2a, 2b, and 3—are indicated. This is the same figure as we used in our previous publication [8]. (B) Drosophila MYCBP (CG17202) protein and the null mutant allele generated in this study. (C) Western blot of dissected fly tissues. (D) Confocal images of germaria from mycbp-EGFP transgenic flies. MYCBP-EGFP (green), Hts (red), and DAPI (blue). Scale bar: 10 μm. (E) Confocal images of egg chambers from w1118 flies. MYCBP (green) and DAPI (blue). MYCBP is expressed in nurse cells, enriched in the developing oocyte (yellow arrow), and is also lowly detectable in somatic follicle cells. Scale bar: 10 μm.
Related Topics
- Type
- other
- OA Status
- green
- OpenAlex ID
- https://openalex.org/W7110892521
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W7110892521Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pgen.1011792.g001Digital Object Identifier
- Title
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MYCBP expression pattern and mutant allele.Work title
- Type
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otherOpenAlex work type
- Publication year
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2025Year of publication
- Publication date
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2025-12-01Full publication date if available
- Authors
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Azali Azlan (10024657), Ryuya Fukunaga (2794186)List of authors in order
- Open access
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YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- Concepts
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Germline, Ovariole, Somatic cell, Biology, Cell biology, Oocyte, Molecular biology, Mutant, Oogenesis, Stem cell, DAPI, Germ line development, Ovary, Meiosis, Confocal, Confocal microscopy, Follicle, Notochord, Germ cell, Developmental biology, Anatomy, Ovarian follicle, Cell culture, Blot, GeneticsTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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