Nasal High-Frequency Oscillatory Ventilation vs. Nasal Continuous Positive Airway Pressure as Therapy for Postextubation Respiratory Failure in Infants After Congenital Heart Surgery Article Swipe
Hong-Lin Wu
,
Yuqing Lei
,
Wen‐Peng Xie
,
Qiang Chen
,
Yi‐Rong Zheng
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3389/fped.2021.700632
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3389/fped.2021.700632
Objective: This study aimed to evaluate the effects of nasal high-frequency oscillatory ventilation (NHFOV) vs. nasal continuous positive airway pressure (NCPAP) on postextubation respiratory failure (PRF) in infants after congenital heart surgery (CHS). Method: Eighty infants underwent postoperative invasive mechanical ventilation for more than 12 h and planned extubation. The infants were randomized to undergo either NHFOV or NCPAP after extubation. Primary outcomes were the incidence of PRF and reintubation, the average PaCO 2 level, the average oxygenation index (OI), and pulmonary recruitment in the early extubation phase. Secondary outcomes included the NCPAP/NHFOV time, length of hospital stay, treatment intolerance, signs of discomfort, pneumothorax, adverse hemodynamic effects, nasal trauma, and mortality. Results: Except for PaCO 2 within 12 after extubation (39.3 ± 5.8 vs. 43.6 ± 7.3 mmHg, p = 0.05), there was no statistically significant difference for any of the primary outcome measure (PRF, reintubation within 12 h after extubation, oxygenation index within 12 h after extubation, or lung volumes on X-ray after extubation) or secondary outcome measures (duration of non-invasive ventilation, duration of hospital stay, ventilation intolerance, signs of discomfort, pneumothorax, nasal trauma, adverse hemodynamic effects, or death prior to discharge), p > 0.1 for each comparison. Conclusion: NHFOV therapy after extubation in infants after CHS was more efficient in improving CO 2 cleaning than NCPAP therapy, but there was no difference in other outcomes (PRF, reintubation, oxygenation index, and pulmonary recruitment).
Related Topics
Concepts
Medicine
Anesthesia
Continuous positive airway pressure
Mechanical ventilation
Pneumothorax
Ventilation (architecture)
Hemodynamics
Peak inspiratory pressure
Oxygenation
Mean airway pressure
Respiratory system
Surgery
Tidal volume
Internal medicine
Engineering
Mechanical engineering
Obstructive sleep apnea
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fped.2021.700632
- https://www.frontiersin.org/articles/10.3389/fped.2021.700632/pdf
- OA Status
- gold
- Cited By
- 5
- References
- 24
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3194896609
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3194896609Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3389/fped.2021.700632Digital Object Identifier
- Title
-
Nasal High-Frequency Oscillatory Ventilation vs. Nasal Continuous Positive Airway Pressure as Therapy for Postextubation Respiratory Failure in Infants After Congenital Heart SurgeryWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-08-16Full publication date if available
- Authors
-
Hong-Lin Wu, Yuqing Lei, Wen‐Peng Xie, Qiang Chen, Yi‐Rong ZhengList of authors in order
- Landing page
-
https://doi.org/10.3389/fped.2021.700632Publisher landing page
- PDF URL
-
https://www.frontiersin.org/articles/10.3389/fped.2021.700632/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.frontiersin.org/articles/10.3389/fped.2021.700632/pdfDirect OA link when available
- Concepts
-
Medicine, Anesthesia, Continuous positive airway pressure, Mechanical ventilation, Pneumothorax, Ventilation (architecture), Hemodynamics, Peak inspiratory pressure, Oxygenation, Mean airway pressure, Respiratory system, Surgery, Tidal volume, Internal medicine, Engineering, Mechanical engineering, Obstructive sleep apneaTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
5Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 2, 2023: 1, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
24Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.75 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.69670044 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |