Neoadjuvant Chemohormonal Therapy Versus Pelvic Lymphadenectomy on Biochemical Recurrence in Patients with High- or Very-High-Risk Prostate Cancer Undergoing Robot-Assisted Radical Prostatectomy Article Swipe
Makoto Kawase
,
Satoshi Washino
,
Takato Nishino
,
Takeshi Yamasaki
,
Hajime Fukushima
,
Kosuke Iwatani
,
Tomoaki Miyagawa
,
Masaki Shimbo
,
Kojiro Ohba
,
Jun Miki
,
Keita Nakane
,
Takuya Koie
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/diseases13040092
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/diseases13040092
Background/Objectives: The effectiveness of robot-assisted radical prostatectomy (RARP) with extended pelvic lymph node dissection (ePLND) in improving oncological outcomes for patients with high- or very-high-risk prostate cancer (HR/VHR-PCa) remains a subject of debate. This study aimed to compare the efficacy of neoadjuvant chemohormonal therapy (NCHT) and ePLND in reducing biochemical recurrence (BCR) in patients with HR/VHR-PCa undergoing RARP. Methods: This retrospective, multicenter cohort study included 1182 patients with HR/VHR-PCa who underwent RARP at six Japanese institutions. Patients were stratified into three groups: those who received NCHT followed by RARP without ePLND (Group 1), those who received neoadjuvant hormonal therapy (NHT) followed by RARP with ePLND (Group 2), and those who underwent RARP with ePLND (Group 3). The primary endpoint was the rate of BCR, while the secondary endpoint was biochemical recurrence-free survival (BRFS) following RARP. Results: Of the 1182 patients, 154 patients were included in Group 1, 97 patients were included in Group 2, and 470 patients were included in Group 3. By the end of the follow-up period, 243 patients (33.8%) had experienced BCR, 27 (3.7%) had progressed to castration-resistant prostate cancer, and 5 (0.7%) had died from PCa. Over a median follow-up period of 41.4 months, BCR occurred in 16.5% of patients in Group 1, 36.1% of patients in Group 2, and 38.9% in Group 3 (p < 0.001). The 3-year BRFS rate was 63.6% in Group 1, 53.1% in Group 2, and 63.9% in Group 3. Conclusions: The findings of this study indicate that NCHT in patients with HR/VHR-PCa undergoing RARP without ePLND may reduce the risk of postoperative BCR compared to those undergoing RARP with ePLND.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/diseases13040092
- https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680
- OA Status
- gold
- References
- 31
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4408902507
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4408902507Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/diseases13040092Digital Object Identifier
- Title
-
Neoadjuvant Chemohormonal Therapy Versus Pelvic Lymphadenectomy on Biochemical Recurrence in Patients with High- or Very-High-Risk Prostate Cancer Undergoing Robot-Assisted Radical ProstatectomyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-03-23Full publication date if available
- Authors
-
Makoto Kawase, Satoshi Washino, Takato Nishino, Takeshi Yamasaki, Hajime Fukushima, Kosuke Iwatani, Tomoaki Miyagawa, Masaki Shimbo, Kojiro Ohba, Jun Miki, Keita Nakane, Takuya KoieList of authors in order
- Landing page
-
https://doi.org/10.3390/diseases13040092Publisher landing page
- PDF URL
-
https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680Direct OA link when available
- Concepts
-
Prostatectomy, Medicine, Lymphadenectomy, Prostate cancer, Urology, Prostate, Cancer, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
31Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4408902507 |
|---|---|
| doi | https://doi.org/10.3390/diseases13040092 |
| ids.doi | https://doi.org/10.3390/diseases13040092 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40277803 |
| ids.openalex | https://openalex.org/W4408902507 |
| fwci | 0.0 |
| type | article |
| title | Neoadjuvant Chemohormonal Therapy Versus Pelvic Lymphadenectomy on Biochemical Recurrence in Patients with High- or Very-High-Risk Prostate Cancer Undergoing Robot-Assisted Radical Prostatectomy |
| biblio.issue | 4 |
| biblio.volume | 13 |
| biblio.last_page | 92 |
| biblio.first_page | 92 |
| topics[0].id | https://openalex.org/T10124 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2740 |
| topics[0].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[0].display_name | Prostate Cancer Diagnosis and Treatment |
| topics[1].id | https://openalex.org/T10543 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9991999864578247 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2740 |
| topics[1].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[1].display_name | Prostate Cancer Treatment and Research |
| topics[2].id | https://openalex.org/T10073 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9890999794006348 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2721 |
| topics[2].subfield.display_name | Hepatology |
| topics[2].display_name | Hepatocellular Carcinoma Treatment and Prognosis |
| is_xpac | False |
| apc_list.value | 1400 |
| apc_list.currency | CHF |
| apc_list.value_usd | 1515 |
| apc_paid.value | 1400 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 1515 |
| concepts[0].id | https://openalex.org/C2779466945 |
| concepts[0].level | 4 |
| concepts[0].score | 0.7850148677825928 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1765251 |
| concepts[0].display_name | Prostatectomy |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.7083349227905273 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2780824555 |
| concepts[2].level | 3 |
| concepts[2].score | 0.5706528425216675 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q1809305 |
| concepts[2].display_name | Lymphadenectomy |
| concepts[3].id | https://openalex.org/C2780192828 |
| concepts[3].level | 3 |
| concepts[3].score | 0.5505884885787964 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q181257 |
| concepts[3].display_name | Prostate cancer |
| concepts[4].id | https://openalex.org/C126894567 |
| concepts[4].level | 1 |
| concepts[4].score | 0.4821326434612274 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q105650 |
| concepts[4].display_name | Urology |
| concepts[5].id | https://openalex.org/C2776235491 |
| concepts[5].level | 3 |
| concepts[5].score | 0.44662952423095703 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q9625 |
| concepts[5].display_name | Prostate |
| concepts[6].id | https://openalex.org/C121608353 |
| concepts[6].level | 2 |
| concepts[6].score | 0.41788309812545776 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q12078 |
| concepts[6].display_name | Cancer |
| concepts[7].id | https://openalex.org/C126322002 |
| concepts[7].level | 1 |
| concepts[7].score | 0.17932948470115662 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[7].display_name | Internal medicine |
| keywords[0].id | https://openalex.org/keywords/prostatectomy |
| keywords[0].score | 0.7850148677825928 |
| keywords[0].display_name | Prostatectomy |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.7083349227905273 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/lymphadenectomy |
| keywords[2].score | 0.5706528425216675 |
| keywords[2].display_name | Lymphadenectomy |
| keywords[3].id | https://openalex.org/keywords/prostate-cancer |
| keywords[3].score | 0.5505884885787964 |
| keywords[3].display_name | Prostate cancer |
| keywords[4].id | https://openalex.org/keywords/urology |
| keywords[4].score | 0.4821326434612274 |
| keywords[4].display_name | Urology |
| keywords[5].id | https://openalex.org/keywords/prostate |
| keywords[5].score | 0.44662952423095703 |
| keywords[5].display_name | Prostate |
| keywords[6].id | https://openalex.org/keywords/cancer |
| keywords[6].score | 0.41788309812545776 |
| keywords[6].display_name | Cancer |
| keywords[7].id | https://openalex.org/keywords/internal-medicine |
| keywords[7].score | 0.17932948470115662 |
| keywords[7].display_name | Internal medicine |
| language | en |
| locations[0].id | doi:10.3390/diseases13040092 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2736521255 |
| locations[0].source.issn | 2079-9721 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2079-9721 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Diseases |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Diseases |
| locations[0].landing_page_url | https://doi.org/10.3390/diseases13040092 |
| locations[1].id | pmid:40277803 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Diseases (Basel, Switzerland) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40277803 |
| locations[2].id | pmh:oai:doaj.org/article:c8ecd741c84a41ec917f65e762829229 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Diseases, Vol 13, Iss 4, p 92 (2025) |
| locations[2].landing_page_url | https://doaj.org/article/c8ecd741c84a41ec917f65e762829229 |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:12026419 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Diseases |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/12026419 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5083530791 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-7269-2462 |
| authorships[0].author.display_name | Makoto Kawase |
| authorships[0].countries | JP |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I42405503 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| authorships[0].institutions[0].id | https://openalex.org/I42405503 |
| authorships[0].institutions[0].ror | https://ror.org/024exxj48 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I42405503 |
| authorships[0].institutions[0].country_code | JP |
| authorships[0].institutions[0].display_name | Gifu University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Makoto Kawase |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| authorships[1].author.id | https://openalex.org/A5063262025 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-9464-6424 |
| authorships[1].author.display_name | Satoshi Washino |
| authorships[1].countries | JP |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I146500386, https://openalex.org/I4210166222 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Urology, Jichi Medical University Saitama Medical Center, Saitama 3300834, Japan |
| authorships[1].institutions[0].id | https://openalex.org/I146500386 |
| authorships[1].institutions[0].ror | https://ror.org/010hz0g26 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I146500386 |
| authorships[1].institutions[0].country_code | JP |
| authorships[1].institutions[0].display_name | Jichi Medical University |
| authorships[1].institutions[1].id | https://openalex.org/I4210166222 |
| authorships[1].institutions[1].ror | https://ror.org/05rq8j339 |
| authorships[1].institutions[1].type | healthcare |
| authorships[1].institutions[1].lineage | https://openalex.org/I4210166222 |
| authorships[1].institutions[1].country_code | JP |
| authorships[1].institutions[1].display_name | Jichi Medical University Saitama Medical Center |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Satoshi Washino |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Urology, Jichi Medical University Saitama Medical Center, Saitama 3300834, Japan |
| authorships[2].author.id | https://openalex.org/A5000878736 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-6014-5020 |
| authorships[2].author.display_name | Takato Nishino |
| authorships[2].countries | JP |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210087594 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Urology, St. Luke's International Hospital, Tokyo 1048560, Japan |
| authorships[2].institutions[0].id | https://openalex.org/I4210087594 |
| authorships[2].institutions[0].ror | https://ror.org/002wydw38 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210087594 |
| authorships[2].institutions[0].country_code | JP |
| authorships[2].institutions[0].display_name | St. Luke's International Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Takato Nishino |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Urology, St. Luke's International Hospital, Tokyo 1048560, Japan |
| authorships[3].author.id | https://openalex.org/A5102367813 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Takeshi Yamasaki |
| authorships[3].countries | JP |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4387152983, https://openalex.org/I69740276 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Urology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 5458585, Japan |
| authorships[3].institutions[0].id | https://openalex.org/I4387152983 |
| authorships[3].institutions[0].ror | https://ror.org/01hvx5h04 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I4387152983 |
| authorships[3].institutions[0].country_code | |
| authorships[3].institutions[0].display_name | Osaka Metropolitan University |
| authorships[3].institutions[1].id | https://openalex.org/I69740276 |
| authorships[3].institutions[1].ror | https://ror.org/00ws30h19 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I69740276 |
| authorships[3].institutions[1].country_code | JP |
| authorships[3].institutions[1].display_name | Tokyo Metropolitan University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Takeshi Yamasaki |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Urology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 5458585, Japan |
| authorships[4].author.id | https://openalex.org/A5056226242 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-0547-3208 |
| authorships[4].author.display_name | Hajime Fukushima |
| authorships[4].countries | JP |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210165237 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki 8528501, Japan |
| authorships[4].institutions[0].id | https://openalex.org/I4210165237 |
| authorships[4].institutions[0].ror | https://ror.org/05kd3f793 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210165237 |
| authorships[4].institutions[0].country_code | JP |
| authorships[4].institutions[0].display_name | Nagasaki University Hospital |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Hajime Fukushima |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki 8528501, Japan |
| authorships[5].author.id | https://openalex.org/A5113360231 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Kosuke Iwatani |
| authorships[5].countries | JP |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I115498069, https://openalex.org/I4210137610 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwa 2778567, Japan |
| authorships[5].institutions[0].id | https://openalex.org/I4210137610 |
| authorships[5].institutions[0].ror | https://ror.org/0491dch03 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210137610 |
| authorships[5].institutions[0].country_code | JP |
| authorships[5].institutions[0].display_name | Jikei University Kashiwa hospital |
| authorships[5].institutions[1].id | https://openalex.org/I115498069 |
| authorships[5].institutions[1].ror | https://ror.org/039ygjf22 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I115498069 |
| authorships[5].institutions[1].country_code | JP |
| authorships[5].institutions[1].display_name | Jikei University School of Medicine |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Kosuke Iwatani |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwa 2778567, Japan |
| authorships[6].author.id | https://openalex.org/A5037773176 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-9867-0229 |
| authorships[6].author.display_name | Tomoaki Miyagawa |
| authorships[6].countries | JP |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I146500386, https://openalex.org/I4210166222 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Urology, Jichi Medical University Saitama Medical Center, Saitama 3300834, Japan |
| authorships[6].institutions[0].id | https://openalex.org/I146500386 |
| authorships[6].institutions[0].ror | https://ror.org/010hz0g26 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I146500386 |
| authorships[6].institutions[0].country_code | JP |
| authorships[6].institutions[0].display_name | Jichi Medical University |
| authorships[6].institutions[1].id | https://openalex.org/I4210166222 |
| authorships[6].institutions[1].ror | https://ror.org/05rq8j339 |
| authorships[6].institutions[1].type | healthcare |
| authorships[6].institutions[1].lineage | https://openalex.org/I4210166222 |
| authorships[6].institutions[1].country_code | JP |
| authorships[6].institutions[1].display_name | Jichi Medical University Saitama Medical Center |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Tomoaki Miyagawa |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Urology, Jichi Medical University Saitama Medical Center, Saitama 3300834, Japan |
| authorships[7].author.id | https://openalex.org/A5045555834 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-0407-7123 |
| authorships[7].author.display_name | Masaki Shimbo |
| authorships[7].countries | JP |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210087594 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Urology, St. Luke's International Hospital, Tokyo 1048560, Japan |
| authorships[7].institutions[0].id | https://openalex.org/I4210087594 |
| authorships[7].institutions[0].ror | https://ror.org/002wydw38 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210087594 |
| authorships[7].institutions[0].country_code | JP |
| authorships[7].institutions[0].display_name | St. Luke's International Hospital |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Masaki Shimbo |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Urology, St. Luke's International Hospital, Tokyo 1048560, Japan |
| authorships[8].author.id | https://openalex.org/A5064560515 |
| authorships[8].author.orcid | https://orcid.org/0000-0003-2841-1998 |
| authorships[8].author.display_name | Kojiro Ohba |
| authorships[8].countries | JP |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210165237 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki 8528501, Japan |
| authorships[8].institutions[0].id | https://openalex.org/I4210165237 |
| authorships[8].institutions[0].ror | https://ror.org/05kd3f793 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210165237 |
| authorships[8].institutions[0].country_code | JP |
| authorships[8].institutions[0].display_name | Nagasaki University Hospital |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Kojiro Ohba |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Department of Urology and Renal Transplantation, Nagasaki University Hospital, Nagasaki 8528501, Japan |
| authorships[9].author.id | https://openalex.org/A5076609835 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | Jun Miki |
| authorships[9].countries | JP |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I115498069, https://openalex.org/I4210137610 |
| authorships[9].affiliations[0].raw_affiliation_string | Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwa 2778567, Japan |
| authorships[9].institutions[0].id | https://openalex.org/I4210137610 |
| authorships[9].institutions[0].ror | https://ror.org/0491dch03 |
| authorships[9].institutions[0].type | healthcare |
| authorships[9].institutions[0].lineage | https://openalex.org/I4210137610 |
| authorships[9].institutions[0].country_code | JP |
| authorships[9].institutions[0].display_name | Jikei University Kashiwa hospital |
| authorships[9].institutions[1].id | https://openalex.org/I115498069 |
| authorships[9].institutions[1].ror | https://ror.org/039ygjf22 |
| authorships[9].institutions[1].type | education |
| authorships[9].institutions[1].lineage | https://openalex.org/I115498069 |
| authorships[9].institutions[1].country_code | JP |
| authorships[9].institutions[1].display_name | Jikei University School of Medicine |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Jun Miki |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwa 2778567, Japan |
| authorships[10].author.id | https://openalex.org/A5051919877 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-2589-1722 |
| authorships[10].author.display_name | Keita Nakane |
| authorships[10].countries | JP |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I42405503 |
| authorships[10].affiliations[0].raw_affiliation_string | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| authorships[10].institutions[0].id | https://openalex.org/I42405503 |
| authorships[10].institutions[0].ror | https://ror.org/024exxj48 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I42405503 |
| authorships[10].institutions[0].country_code | JP |
| authorships[10].institutions[0].display_name | Gifu University |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Keita Nakane |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| authorships[11].author.id | https://openalex.org/A5055415323 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-2980-127X |
| authorships[11].author.display_name | Takuya Koie |
| authorships[11].countries | JP |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I42405503 |
| authorships[11].affiliations[0].raw_affiliation_string | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| authorships[11].institutions[0].id | https://openalex.org/I42405503 |
| authorships[11].institutions[0].ror | https://ror.org/024exxj48 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I42405503 |
| authorships[11].institutions[0].country_code | JP |
| authorships[11].institutions[0].display_name | Gifu University |
| authorships[11].author_position | last |
| authorships[11].raw_author_name | Takuya Koie |
| authorships[11].is_corresponding | True |
| authorships[11].raw_affiliation_strings | Department of Urology, Graduate School of Medicine, Gifu University, Gifu 5011194, Japan |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Neoadjuvant Chemohormonal Therapy Versus Pelvic Lymphadenectomy on Biochemical Recurrence in Patients with High- or Very-High-Risk Prostate Cancer Undergoing Robot-Assisted Radical Prostatectomy |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10124 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2740 |
| primary_topic.subfield.display_name | Pulmonary and Respiratory Medicine |
| primary_topic.display_name | Prostate Cancer Diagnosis and Treatment |
| related_works | https://openalex.org/W4401322566, https://openalex.org/W2137571400, https://openalex.org/W3015759778, https://openalex.org/W2088520467, https://openalex.org/W2075763133, https://openalex.org/W2376423713, https://openalex.org/W1988513079, https://openalex.org/W1888477076, https://openalex.org/W2030383011, https://openalex.org/W1583600832 |
| cited_by_count | 0 |
| locations_count | 4 |
| best_oa_location.id | doi:10.3390/diseases13040092 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2736521255 |
| best_oa_location.source.issn | 2079-9721 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2079-9721 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Diseases |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Diseases |
| best_oa_location.landing_page_url | https://doi.org/10.3390/diseases13040092 |
| primary_location.id | doi:10.3390/diseases13040092 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2736521255 |
| primary_location.source.issn | 2079-9721 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2079-9721 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Diseases |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2079-9721/13/4/92/pdf?version=1742882680 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Diseases |
| primary_location.landing_page_url | https://doi.org/10.3390/diseases13040092 |
| publication_date | 2025-03-23 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W1986345593, https://openalex.org/W2033645999, https://openalex.org/W2340422569, https://openalex.org/W3111010446, https://openalex.org/W3112599791, https://openalex.org/W3153693580, https://openalex.org/W4310037012, https://openalex.org/W3134664673, https://openalex.org/W4295080482, https://openalex.org/W1970316517, https://openalex.org/W2064766427, https://openalex.org/W2893760555, https://openalex.org/W4366827438, https://openalex.org/W4384665377, https://openalex.org/W2725987651, https://openalex.org/W2037610329, https://openalex.org/W3097158220, https://openalex.org/W2589816513, https://openalex.org/W2146141124, https://openalex.org/W2144173184, https://openalex.org/W4406660574, https://openalex.org/W2053198390, https://openalex.org/W2083043726, https://openalex.org/W2755748742, https://openalex.org/W4229058820, https://openalex.org/W2593612776, https://openalex.org/W1606286286, https://openalex.org/W2116692433, https://openalex.org/W3085802586, https://openalex.org/W4323035781, https://openalex.org/W3140238675 |
| referenced_works_count | 31 |
| abstract_inverted_index.3 | 217 |
| abstract_inverted_index.5 | 184 |
| abstract_inverted_index.a | 29, 191 |
| abstract_inverted_index.(p | 218 |
| abstract_inverted_index.1, | 146, 206, 229 |
| abstract_inverted_index.2, | 153, 212, 233 |
| abstract_inverted_index.27 | 175 |
| abstract_inverted_index.3. | 161, 238 |
| abstract_inverted_index.97 | 147 |
| abstract_inverted_index.By | 162 |
| abstract_inverted_index.Of | 136 |
| abstract_inverted_index.at | 72 |
| abstract_inverted_index.by | 87, 101 |
| abstract_inverted_index.in | 15, 47, 52, 144, 151, 159, 200, 204, 210, 215, 227, 231, 236, 248 |
| abstract_inverted_index.of | 3, 31, 40, 122, 165, 195, 202, 208, 242, 260 |
| abstract_inverted_index.or | 23 |
| abstract_inverted_index.to | 36, 179, 264 |
| abstract_inverted_index.1), | 92 |
| abstract_inverted_index.154 | 140 |
| abstract_inverted_index.2), | 106 |
| abstract_inverted_index.243 | 169 |
| abstract_inverted_index.3). | 115 |
| abstract_inverted_index.470 | 155 |
| abstract_inverted_index.BCR | 198, 262 |
| abstract_inverted_index.The | 1, 116, 221, 240 |
| abstract_inverted_index.and | 45, 107, 154, 183, 213, 234 |
| abstract_inverted_index.end | 164 |
| abstract_inverted_index.for | 19 |
| abstract_inverted_index.had | 172, 177, 186 |
| abstract_inverted_index.may | 256 |
| abstract_inverted_index.six | 73 |
| abstract_inverted_index.the | 38, 120, 125, 137, 163, 166, 258 |
| abstract_inverted_index.was | 119, 128, 225 |
| abstract_inverted_index.who | 69, 83, 94, 109 |
| abstract_inverted_index.< | 219 |
| abstract_inverted_index.1182 | 65, 138 |
| abstract_inverted_index.41.4 | 196 |
| abstract_inverted_index.BCR, | 123, 174 |
| abstract_inverted_index.BRFS | 223 |
| abstract_inverted_index.NCHT | 85, 247 |
| abstract_inverted_index.Over | 190 |
| abstract_inverted_index.PCa. | 189 |
| abstract_inverted_index.RARP | 71, 88, 102, 111, 253, 267 |
| abstract_inverted_index.This | 33, 59 |
| abstract_inverted_index.died | 187 |
| abstract_inverted_index.from | 188 |
| abstract_inverted_index.into | 79 |
| abstract_inverted_index.node | 12 |
| abstract_inverted_index.rate | 121, 224 |
| abstract_inverted_index.risk | 259 |
| abstract_inverted_index.that | 246 |
| abstract_inverted_index.this | 243 |
| abstract_inverted_index.were | 77, 142, 149, 157 |
| abstract_inverted_index.with | 8, 21, 54, 67, 103, 112, 250, 268 |
| abstract_inverted_index.(BCR) | 51 |
| abstract_inverted_index.(NHT) | 99 |
| abstract_inverted_index.16.5% | 201 |
| abstract_inverted_index.36.1% | 207 |
| abstract_inverted_index.38.9% | 214 |
| abstract_inverted_index.53.1% | 230 |
| abstract_inverted_index.63.6% | 226 |
| abstract_inverted_index.63.9% | 235 |
| abstract_inverted_index.Group | 145, 152, 160, 205, 211, 216, 228, 232, 237 |
| abstract_inverted_index.RARP. | 57, 134 |
| abstract_inverted_index.aimed | 35 |
| abstract_inverted_index.ePLND | 46, 90, 104, 113, 255 |
| abstract_inverted_index.high- | 22 |
| abstract_inverted_index.lymph | 11 |
| abstract_inverted_index.study | 34, 63, 244 |
| abstract_inverted_index.those | 82, 93, 108, 265 |
| abstract_inverted_index.three | 80 |
| abstract_inverted_index.while | 124 |
| abstract_inverted_index.(0.7%) | 185 |
| abstract_inverted_index.(3.7%) | 176 |
| abstract_inverted_index.(BRFS) | 132 |
| abstract_inverted_index.(Group | 91, 105, 114 |
| abstract_inverted_index.(NCHT) | 44 |
| abstract_inverted_index.(RARP) | 7 |
| abstract_inverted_index.3-year | 222 |
| abstract_inverted_index.cancer | 26 |
| abstract_inverted_index.cohort | 62 |
| abstract_inverted_index.ePLND. | 269 |
| abstract_inverted_index.median | 192 |
| abstract_inverted_index.pelvic | 10 |
| abstract_inverted_index.period | 194 |
| abstract_inverted_index.reduce | 257 |
| abstract_inverted_index.(33.8%) | 171 |
| abstract_inverted_index.(ePLND) | 14 |
| abstract_inverted_index.0.001). | 220 |
| abstract_inverted_index.cancer, | 182 |
| abstract_inverted_index.compare | 37 |
| abstract_inverted_index.debate. | 32 |
| abstract_inverted_index.groups: | 81 |
| abstract_inverted_index.months, | 197 |
| abstract_inverted_index.period, | 168 |
| abstract_inverted_index.primary | 117 |
| abstract_inverted_index.radical | 5 |
| abstract_inverted_index.remains | 28 |
| abstract_inverted_index.subject | 30 |
| abstract_inverted_index.therapy | 43, 98 |
| abstract_inverted_index.without | 89, 254 |
| abstract_inverted_index.Japanese | 74 |
| abstract_inverted_index.Methods: | 58 |
| abstract_inverted_index.Patients | 76 |
| abstract_inverted_index.Results: | 135 |
| abstract_inverted_index.compared | 263 |
| abstract_inverted_index.efficacy | 39 |
| abstract_inverted_index.endpoint | 118, 127 |
| abstract_inverted_index.extended | 9 |
| abstract_inverted_index.findings | 241 |
| abstract_inverted_index.followed | 86, 100 |
| abstract_inverted_index.hormonal | 97 |
| abstract_inverted_index.included | 64, 143, 150, 158 |
| abstract_inverted_index.indicate | 245 |
| abstract_inverted_index.occurred | 199 |
| abstract_inverted_index.outcomes | 18 |
| abstract_inverted_index.patients | 20, 53, 66, 141, 148, 156, 170, 203, 209, 249 |
| abstract_inverted_index.prostate | 25, 181 |
| abstract_inverted_index.received | 84, 95 |
| abstract_inverted_index.reducing | 48 |
| abstract_inverted_index.survival | 131 |
| abstract_inverted_index.follow-up | 167, 193 |
| abstract_inverted_index.following | 133 |
| abstract_inverted_index.improving | 16 |
| abstract_inverted_index.patients, | 139 |
| abstract_inverted_index.secondary | 126 |
| abstract_inverted_index.underwent | 70, 110 |
| abstract_inverted_index.HR/VHR-PCa | 55, 68, 251 |
| abstract_inverted_index.dissection | 13 |
| abstract_inverted_index.progressed | 178 |
| abstract_inverted_index.recurrence | 50 |
| abstract_inverted_index.stratified | 78 |
| abstract_inverted_index.undergoing | 56, 252, 266 |
| abstract_inverted_index.biochemical | 49, 129 |
| abstract_inverted_index.experienced | 173 |
| abstract_inverted_index.multicenter | 61 |
| abstract_inverted_index.neoadjuvant | 41, 96 |
| abstract_inverted_index.oncological | 17 |
| abstract_inverted_index.(HR/VHR-PCa) | 27 |
| abstract_inverted_index.Conclusions: | 239 |
| abstract_inverted_index.chemohormonal | 42 |
| abstract_inverted_index.effectiveness | 2 |
| abstract_inverted_index.institutions. | 75 |
| abstract_inverted_index.postoperative | 261 |
| abstract_inverted_index.prostatectomy | 6 |
| abstract_inverted_index.retrospective, | 60 |
| abstract_inverted_index.robot-assisted | 4 |
| abstract_inverted_index.very-high-risk | 24 |
| abstract_inverted_index.recurrence-free | 130 |
| abstract_inverted_index.castration-resistant | 180 |
| abstract_inverted_index.Background/Objectives: | 0 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5055415323 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 12 |
| corresponding_institution_ids | https://openalex.org/I42405503 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7400000095367432 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.14048496 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |