Neonatal antibiotic exposure impairs child growth during the first six years of life by perturbing intestinal microbial colonization Article Swipe
Atara Uzan-Yulzari
,
Olli Turta
,
Anna Belogolovski
,
Ziv Oren
,
Christina Kunz
,
Sarah Perschbacher
,
Hadar Neuman
,
Edoardo Pasolli
,
Aia Oz
,
Hila Ben-Amram
,
Himanshu Kumar
,
Helena Ollila
,
Anne Kaljonen
,
Erika Isolauri
,
Seppo Salminen
,
Hanna Lagström
,
Nicola Segata
,
Itai Sharon
,
Yoram Louzoun
,
Regina Ensenauer
,
Samuli Rautava
,
Omry Koren
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1038/s41467-020-20495-4
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1038/s41467-020-20495-4
Exposure to antibiotics in the first days of life is thought to affect various physiological aspects of neonatal development. Here, we investigate the long-term impact of antibiotic treatment in the neonatal period and early childhood on child growth in an unselected birth cohort of 12,422 children born at full term. We find significant attenuation of weight and height gain during the first 6 years of life after neonatal antibiotic exposure in boys, but not in girls, after adjusting for potential confounders. In contrast, antibiotic use after the neonatal period but during the first 6 years of life is associated with significantly higher body mass index throughout the study period in both boys and girls. Neonatal antibiotic exposure is associated with significant differences in the gut microbiome, particularly in decreased abundance and diversity of fecal Bifidobacteria until 2 years of age. Finally, we demonstrate that fecal microbiota transplant from antibiotic-exposed children to germ-free male, but not female, mice results in significant growth impairment. Thus, we conclude that neonatal antibiotic exposure is associated with a long-term gut microbiome perturbation and may result in reduced growth in boys during the first six years of life while antibiotic use later in childhood is associated with increased body mass index.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41467-020-20495-4
- https://www.nature.com/articles/s41467-020-20495-4.pdf
- OA Status
- gold
- Cited By
- 200
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3122147898
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3122147898Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1038/s41467-020-20495-4Digital Object Identifier
- Title
-
Neonatal antibiotic exposure impairs child growth during the first six years of life by perturbing intestinal microbial colonizationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-01-26Full publication date if available
- Authors
-
Atara Uzan-Yulzari, Olli Turta, Anna Belogolovski, Ziv Oren, Christina Kunz, Sarah Perschbacher, Hadar Neuman, Edoardo Pasolli, Aia Oz, Hila Ben-Amram, Himanshu Kumar, Helena Ollila, Anne Kaljonen, Erika Isolauri, Seppo Salminen, Hanna Lagström, Nicola Segata, Itai Sharon, Yoram Louzoun, Regina Ensenauer, Samuli Rautava, Omry KorenList of authors in order
- Landing page
-
https://doi.org/10.1038/s41467-020-20495-4Publisher landing page
- PDF URL
-
https://www.nature.com/articles/s41467-020-20495-4.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.nature.com/articles/s41467-020-20495-4.pdfDirect OA link when available
- Concepts
-
Antibiotics, Microbiome, Body mass index, Confounding, Medicine, Feces, Physiology, Early childhood, Pediatrics, Biology, Internal medicine, Microbiology, Bioinformatics, Psychology, Developmental psychologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
200Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 30, 2024: 61, 2023: 42, 2022: 31, 2021: 36Per-year citation counts (last 5 years)
- References (count)
-
55Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3122147898 |
|---|---|
| doi | https://doi.org/10.1038/s41467-020-20495-4 |
| ids.doi | https://doi.org/10.1038/s41467-020-20495-4 |
| ids.mag | 3122147898 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/33500411 |
| ids.openalex | https://openalex.org/W3122147898 |
| fwci | 16.77557749 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000818 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Animals |
| mesh[1].qualifier_ui | Q000009 |
| mesh[1].descriptor_ui | D000900 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | adverse effects |
| mesh[1].descriptor_name | Anti-Bacterial Agents |
| mesh[2].qualifier_ui | Q000188 |
| mesh[2].descriptor_ui | D001424 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | drug therapy |
| mesh[2].descriptor_name | Bacterial Infections |
| mesh[3].qualifier_ui | Q000187 |
| mesh[3].descriptor_ui | D001827 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | drug effects |
| mesh[3].descriptor_name | Body Height |
| mesh[4].qualifier_ui | Q000502 |
| mesh[4].descriptor_ui | D001827 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | physiology |
| mesh[4].descriptor_name | Body Height |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D015992 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Body Mass Index |
| mesh[6].qualifier_ui | Q000187 |
| mesh[6].descriptor_ui | D001835 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | drug effects |
| mesh[6].descriptor_name | Body Weight |
| mesh[7].qualifier_ui | Q000502 |
| mesh[7].descriptor_ui | D001835 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | physiology |
| mesh[7].descriptor_name | Body Weight |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D002648 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Child |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D002675 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Child, Preschool |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D004195 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Disease Models, Animal |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D000069467 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Fecal Microbiota Transplantation |
| mesh[12].qualifier_ui | Q000382 |
| mesh[12].descriptor_ui | D005243 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | microbiology |
| mesh[12].descriptor_name | Feces |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D005260 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Female |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D005500 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Follow-Up Studies |
| mesh[15].qualifier_ui | Q000187 |
| mesh[15].descriptor_ui | D000069196 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | drug effects |
| mesh[15].descriptor_name | Gastrointestinal Microbiome |
| mesh[16].qualifier_ui | Q000502 |
| mesh[16].descriptor_ui | D000069196 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | physiology |
| mesh[16].descriptor_name | Gastrointestinal Microbiome |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D005856 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Germ-Free Life |
| mesh[18].qualifier_ui | Q000139 |
| mesh[18].descriptor_ui | D006130 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | chemically induced |
| mesh[18].descriptor_name | Growth Disorders |
| mesh[19].qualifier_ui | Q000382 |
| mesh[19].descriptor_ui | D006130 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | microbiology |
| mesh[19].descriptor_name | Growth Disorders |
| mesh[20].qualifier_ui | Q000503 |
| mesh[20].descriptor_ui | D006130 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | physiopathology |
| mesh[20].descriptor_name | Growth Disorders |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006801 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Humans |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D007231 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Infant, Newborn |
| mesh[23].qualifier_ui | Q000382 |
| mesh[23].descriptor_ui | D007413 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | microbiology |
| mesh[23].descriptor_name | Intestinal Mucosa |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D008297 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Male |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D051379 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Mice |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D011247 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Pregnancy |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D012307 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Risk Factors |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D012737 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Sex Factors |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D000818 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Animals |
| mesh[30].qualifier_ui | Q000009 |
| mesh[30].descriptor_ui | D000900 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | adverse effects |
| mesh[30].descriptor_name | Anti-Bacterial Agents |
| mesh[31].qualifier_ui | Q000188 |
| mesh[31].descriptor_ui | D001424 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | drug therapy |
| mesh[31].descriptor_name | Bacterial Infections |
| mesh[32].qualifier_ui | Q000187 |
| mesh[32].descriptor_ui | D001827 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | drug effects |
| mesh[32].descriptor_name | Body Height |
| mesh[33].qualifier_ui | Q000502 |
| mesh[33].descriptor_ui | D001827 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | physiology |
| mesh[33].descriptor_name | Body Height |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D015992 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Body Mass Index |
| mesh[35].qualifier_ui | Q000187 |
| mesh[35].descriptor_ui | D001835 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | drug effects |
| mesh[35].descriptor_name | Body Weight |
| mesh[36].qualifier_ui | Q000502 |
| mesh[36].descriptor_ui | D001835 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | physiology |
| mesh[36].descriptor_name | Body Weight |
| mesh[37].qualifier_ui | |
| mesh[37].descriptor_ui | D002648 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | |
| mesh[37].descriptor_name | Child |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D002675 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Child, Preschool |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D004195 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Disease Models, Animal |
| mesh[40].qualifier_ui | |
| mesh[40].descriptor_ui | D000069467 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | |
| mesh[40].descriptor_name | Fecal Microbiota Transplantation |
| mesh[41].qualifier_ui | Q000382 |
| mesh[41].descriptor_ui | D005243 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | microbiology |
| mesh[41].descriptor_name | Feces |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D005260 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Female |
| mesh[43].qualifier_ui | |
| mesh[43].descriptor_ui | D005500 |
| mesh[43].is_major_topic | False |
| mesh[43].qualifier_name | |
| mesh[43].descriptor_name | Follow-Up Studies |
| mesh[44].qualifier_ui | Q000187 |
| mesh[44].descriptor_ui | D000069196 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | drug effects |
| mesh[44].descriptor_name | Gastrointestinal Microbiome |
| mesh[45].qualifier_ui | Q000502 |
| mesh[45].descriptor_ui | D000069196 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | physiology |
| mesh[45].descriptor_name | Gastrointestinal Microbiome |
| mesh[46].qualifier_ui | |
| mesh[46].descriptor_ui | D005856 |
| mesh[46].is_major_topic | False |
| mesh[46].qualifier_name | |
| mesh[46].descriptor_name | Germ-Free Life |
| mesh[47].qualifier_ui | Q000139 |
| mesh[47].descriptor_ui | D006130 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | chemically induced |
| mesh[47].descriptor_name | Growth Disorders |
| mesh[48].qualifier_ui | Q000382 |
| mesh[48].descriptor_ui | D006130 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | microbiology |
| mesh[48].descriptor_name | Growth Disorders |
| mesh[49].qualifier_ui | Q000503 |
| mesh[49].descriptor_ui | D006130 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | physiopathology |
| mesh[49].descriptor_name | Growth Disorders |
| type | article |
| title | Neonatal antibiotic exposure impairs child growth during the first six years of life by perturbing intestinal microbial colonization |
| biblio.issue | 1 |
| biblio.volume | 12 |
| biblio.last_page | 443 |
| biblio.first_page | 443 |
| topics[0].id | https://openalex.org/T10066 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9994000196456909 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | Gut microbiota and health |
| topics[1].id | https://openalex.org/T11541 |
| topics[1].field.id | https://openalex.org/fields/32 |
| topics[1].field.display_name | Psychology |
| topics[1].score | 0.9825999736785889 |
| topics[1].domain.id | https://openalex.org/domains/2 |
| topics[1].domain.display_name | Social Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/3207 |
| topics[1].subfield.display_name | Social Psychology |
| topics[1].display_name | Neuroendocrine regulation and behavior |
| topics[2].id | https://openalex.org/T10786 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9656000137329102 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2739 |
| topics[2].subfield.display_name | Public Health, Environmental and Occupational Health |
| topics[2].display_name | Maternal Mental Health During Pregnancy and Postpartum |
| is_xpac | False |
| apc_list.value | 3920 |
| apc_list.currency | GBP |
| apc_list.value_usd | 4808 |
| apc_paid.value | 3920 |
| apc_paid.currency | GBP |
| apc_paid.value_usd | 4808 |
| concepts[0].id | https://openalex.org/C501593827 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8015117645263672 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q12187 |
| concepts[0].display_name | Antibiotics |
| concepts[1].id | https://openalex.org/C143121216 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6779482960700989 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1330402 |
| concepts[1].display_name | Microbiome |
| concepts[2].id | https://openalex.org/C2780221984 |
| concepts[2].level | 2 |
| concepts[2].score | 0.5294734239578247 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q131191 |
| concepts[2].display_name | Body mass index |
| concepts[3].id | https://openalex.org/C77350462 |
| concepts[3].level | 2 |
| concepts[3].score | 0.5112545490264893 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q1125472 |
| concepts[3].display_name | Confounding |
| concepts[4].id | https://openalex.org/C71924100 |
| concepts[4].level | 0 |
| concepts[4].score | 0.4970085918903351 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[4].display_name | Medicine |
| concepts[5].id | https://openalex.org/C61716771 |
| concepts[5].level | 2 |
| concepts[5].score | 0.46126797795295715 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q496 |
| concepts[5].display_name | Feces |
| concepts[6].id | https://openalex.org/C42407357 |
| concepts[6].level | 1 |
| concepts[6].score | 0.44461798667907715 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q521 |
| concepts[6].display_name | Physiology |
| concepts[7].id | https://openalex.org/C2777082460 |
| concepts[7].level | 2 |
| concepts[7].score | 0.44452497363090515 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q3377398 |
| concepts[7].display_name | Early childhood |
| concepts[8].id | https://openalex.org/C187212893 |
| concepts[8].level | 1 |
| concepts[8].score | 0.4412311613559723 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q123028 |
| concepts[8].display_name | Pediatrics |
| concepts[9].id | https://openalex.org/C86803240 |
| concepts[9].level | 0 |
| concepts[9].score | 0.3641822338104248 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[9].display_name | Biology |
| concepts[10].id | https://openalex.org/C126322002 |
| concepts[10].level | 1 |
| concepts[10].score | 0.27297574281692505 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[10].display_name | Internal medicine |
| concepts[11].id | https://openalex.org/C89423630 |
| concepts[11].level | 1 |
| concepts[11].score | 0.11613926291465759 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q7193 |
| concepts[11].display_name | Microbiology |
| concepts[12].id | https://openalex.org/C60644358 |
| concepts[12].level | 1 |
| concepts[12].score | 0.07664713263511658 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q128570 |
| concepts[12].display_name | Bioinformatics |
| concepts[13].id | https://openalex.org/C15744967 |
| concepts[13].level | 0 |
| concepts[13].score | 0.0 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q9418 |
| concepts[13].display_name | Psychology |
| concepts[14].id | https://openalex.org/C138496976 |
| concepts[14].level | 1 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q175002 |
| concepts[14].display_name | Developmental psychology |
| keywords[0].id | https://openalex.org/keywords/antibiotics |
| keywords[0].score | 0.8015117645263672 |
| keywords[0].display_name | Antibiotics |
| keywords[1].id | https://openalex.org/keywords/microbiome |
| keywords[1].score | 0.6779482960700989 |
| keywords[1].display_name | Microbiome |
| keywords[2].id | https://openalex.org/keywords/body-mass-index |
| keywords[2].score | 0.5294734239578247 |
| keywords[2].display_name | Body mass index |
| keywords[3].id | https://openalex.org/keywords/confounding |
| keywords[3].score | 0.5112545490264893 |
| keywords[3].display_name | Confounding |
| keywords[4].id | https://openalex.org/keywords/medicine |
| keywords[4].score | 0.4970085918903351 |
| keywords[4].display_name | Medicine |
| keywords[5].id | https://openalex.org/keywords/feces |
| keywords[5].score | 0.46126797795295715 |
| keywords[5].display_name | Feces |
| keywords[6].id | https://openalex.org/keywords/physiology |
| keywords[6].score | 0.44461798667907715 |
| keywords[6].display_name | Physiology |
| keywords[7].id | https://openalex.org/keywords/early-childhood |
| keywords[7].score | 0.44452497363090515 |
| keywords[7].display_name | Early childhood |
| keywords[8].id | https://openalex.org/keywords/pediatrics |
| keywords[8].score | 0.4412311613559723 |
| keywords[8].display_name | Pediatrics |
| keywords[9].id | https://openalex.org/keywords/biology |
| keywords[9].score | 0.3641822338104248 |
| keywords[9].display_name | Biology |
| keywords[10].id | https://openalex.org/keywords/internal-medicine |
| keywords[10].score | 0.27297574281692505 |
| keywords[10].display_name | Internal medicine |
| keywords[11].id | https://openalex.org/keywords/microbiology |
| keywords[11].score | 0.11613926291465759 |
| keywords[11].display_name | Microbiology |
| keywords[12].id | https://openalex.org/keywords/bioinformatics |
| keywords[12].score | 0.07664713263511658 |
| keywords[12].display_name | Bioinformatics |
| language | en |
| locations[0].id | doi:10.1038/s41467-020-20495-4 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S64187185 |
| locations[0].source.issn | 2041-1723 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2041-1723 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Nature Communications |
| locations[0].source.host_organization | https://openalex.org/P4310319908 |
| locations[0].source.host_organization_name | Nature Portfolio |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310319908 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.nature.com/articles/s41467-020-20495-4.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Nature Communications |
| locations[0].landing_page_url | https://doi.org/10.1038/s41467-020-20495-4 |
| locations[1].id | pmid:33500411 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Nature communications |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/33500411 |
| locations[2].id | pmh:oai:iris.unitn.it:11572/355049 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306401913 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | Institutional Research Information System (Università degli Studi di Trento) |
| locations[2].source.host_organization | https://openalex.org/I193223587 |
| locations[2].source.host_organization_name | University of Trento |
| locations[2].source.host_organization_lineage | https://openalex.org/I193223587 |
| locations[2].license | cc-by |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | info:eu-repo/semantics/article |
| locations[2].license_id | https://openalex.org/licenses/cc-by |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | https://www.nature.com/articles/s41467-020-20495-4 |
| locations[3].id | pmh:oai:doaj.org/article:19797fc3ddc54066b83f9bd51bdb82e5 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].source.host_organization_lineage | |
| locations[3].license | cc-by-sa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| locations[3].landing_page_url | https://doaj.org/article/19797fc3ddc54066b83f9bd51bdb82e5 |
| locations[4].id | pmh:oai:helda.helsinki.fi:10138/328064 |
| locations[4].is_oa | False |
| locations[4].source.id | https://openalex.org/S4306401476 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | Helda (University of Helsinki) |
| locations[4].source.host_organization | https://openalex.org/I133731052 |
| locations[4].source.host_organization_name | University of Helsinki |
| locations[4].source.host_organization_lineage | https://openalex.org/I133731052 |
| locations[4].license | |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Article |
| locations[4].license_id | |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | |
| locations[4].landing_page_url | http://hdl.handle.net/10138/328064 |
| locations[5].id | pmh:oai:pubmedcentral.nih.gov:7838415 |
| locations[5].is_oa | True |
| locations[5].source.id | https://openalex.org/S2764455111 |
| locations[5].source.issn | |
| locations[5].source.type | repository |
| locations[5].source.is_oa | False |
| locations[5].source.issn_l | |
| locations[5].source.is_core | False |
| locations[5].source.is_in_doaj | False |
| locations[5].source.display_name | PubMed Central |
| locations[5].source.host_organization | https://openalex.org/I1299303238 |
| locations[5].source.host_organization_name | National Institutes of Health |
| locations[5].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[5].license | other-oa |
| locations[5].pdf_url | |
| locations[5].version | submittedVersion |
| locations[5].raw_type | Text |
| locations[5].license_id | https://openalex.org/licenses/other-oa |
| locations[5].is_accepted | False |
| locations[5].is_published | False |
| locations[5].raw_source_name | Nat Commun |
| locations[5].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7838415 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5089519748 |
| authorships[0].author.orcid | https://orcid.org/0009-0005-3169-8418 |
| authorships[0].author.display_name | Atara Uzan-Yulzari |
| authorships[0].countries | IL |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[0].affiliations[0].raw_affiliation_string | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[0].institutions[0].id | https://openalex.org/I13955877 |
| authorships[0].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[0].institutions[0].country_code | IL |
| authorships[0].institutions[0].display_name | Bar-Ilan University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Atara Uzan-Yulzari |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[1].author.id | https://openalex.org/A5022175282 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-3690-6192 |
| authorships[1].author.display_name | Olli Turta |
| authorships[1].countries | FI |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I155660961, https://openalex.org/I2801970007 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[1].institutions[0].id | https://openalex.org/I2801970007 |
| authorships[1].institutions[0].ror | https://ror.org/05dbzj528 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I2801970007, https://openalex.org/I4210127022 |
| authorships[1].institutions[0].country_code | FI |
| authorships[1].institutions[0].display_name | Turku University Hospital |
| authorships[1].institutions[1].id | https://openalex.org/I155660961 |
| authorships[1].institutions[1].ror | https://ror.org/05vghhr25 |
| authorships[1].institutions[1].type | education |
| authorships[1].institutions[1].lineage | https://openalex.org/I155660961 |
| authorships[1].institutions[1].country_code | FI |
| authorships[1].institutions[1].display_name | University of Turku |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Olli Turta |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[2].author.id | https://openalex.org/A5033397995 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Anna Belogolovski |
| authorships[2].countries | IL |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel |
| authorships[2].institutions[0].id | https://openalex.org/I13955877 |
| authorships[2].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[2].institutions[0].country_code | IL |
| authorships[2].institutions[0].display_name | Bar-Ilan University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Anna Belogolovski |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel |
| authorships[3].author.id | https://openalex.org/A5003289346 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-6466-6950 |
| authorships[3].author.display_name | Ziv Oren |
| authorships[3].countries | IL |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[3].affiliations[0].raw_affiliation_string | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[3].institutions[0].id | https://openalex.org/I13955877 |
| authorships[3].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[3].institutions[0].country_code | IL |
| authorships[3].institutions[0].display_name | Bar-Ilan University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Oren Ziv |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[4].author.id | https://openalex.org/A5059718263 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-0528-3527 |
| authorships[4].author.display_name | Christina Kunz |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210147723 |
| authorships[4].affiliations[0].raw_affiliation_string | Institute of Child Nutrition, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany |
| authorships[4].institutions[0].id | https://openalex.org/I4210147723 |
| authorships[4].institutions[0].ror | https://ror.org/045gmmg53 |
| authorships[4].institutions[0].type | government |
| authorships[4].institutions[0].lineage | https://openalex.org/I2801963157, https://openalex.org/I4210147723 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Max Rubner Institut |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Christina Kunz |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Institute of Child Nutrition, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany |
| authorships[5].author.id | https://openalex.org/A5069532215 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Sarah Perschbacher |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I8204097 |
| authorships[5].affiliations[0].raw_affiliation_string | Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany |
| authorships[5].institutions[0].id | https://openalex.org/I8204097 |
| authorships[5].institutions[0].ror | https://ror.org/05591te55 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I8204097 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | Ludwig-Maximilians-Universität München |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Sarah Perschbacher |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany |
| authorships[6].author.id | https://openalex.org/A5018182887 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Hadar Neuman |
| authorships[6].countries | IL |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[6].affiliations[0].raw_affiliation_string | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[6].institutions[0].id | https://openalex.org/I13955877 |
| authorships[6].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[6].institutions[0].country_code | IL |
| authorships[6].institutions[0].display_name | Bar-Ilan University |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Hadar Neuman |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[7].author.id | https://openalex.org/A5075665406 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-0799-3490 |
| authorships[7].author.display_name | Edoardo Pasolli |
| authorships[7].countries | IT |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I193223587 |
| authorships[7].affiliations[0].raw_affiliation_string | Department CIBIO, University of Trento, Trento, Italy |
| authorships[7].institutions[0].id | https://openalex.org/I193223587 |
| authorships[7].institutions[0].ror | https://ror.org/05trd4x28 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I193223587 |
| authorships[7].institutions[0].country_code | IT |
| authorships[7].institutions[0].display_name | University of Trento |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Edoardo Pasolli |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department CIBIO, University of Trento, Trento, Italy |
| authorships[8].author.id | https://openalex.org/A5018576201 |
| authorships[8].author.orcid | https://orcid.org/0009-0008-7568-5549 |
| authorships[8].author.display_name | Aia Oz |
| authorships[8].countries | IL |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210145032 |
| authorships[8].affiliations[0].raw_affiliation_string | Migal – Galilee Research Institute, Qiryat Shemona, Israel |
| authorships[8].institutions[0].id | https://openalex.org/I4210145032 |
| authorships[8].institutions[0].ror | https://ror.org/04kaqnt29 |
| authorships[8].institutions[0].type | facility |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210145032 |
| authorships[8].institutions[0].country_code | IL |
| authorships[8].institutions[0].display_name | Migal - Galilee Technology Center |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Aia Oz |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Migal – Galilee Research Institute, Qiryat Shemona, Israel |
| authorships[9].author.id | https://openalex.org/A5068839023 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | Hila Ben-Amram |
| authorships[9].countries | IL |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[9].affiliations[0].raw_affiliation_string | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[9].institutions[0].id | https://openalex.org/I13955877 |
| authorships[9].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[9].institutions[0].country_code | IL |
| authorships[9].institutions[0].display_name | Bar-Ilan University |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Hila Ben-Amram |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[10].author.id | https://openalex.org/A5086779569 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-9749-8620 |
| authorships[10].author.display_name | Himanshu Kumar |
| authorships[10].countries | FI |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I155660961 |
| authorships[10].affiliations[0].raw_affiliation_string | Functional Foods Forum, University of Turku, Turku, Finland |
| authorships[10].institutions[0].id | https://openalex.org/I155660961 |
| authorships[10].institutions[0].ror | https://ror.org/05vghhr25 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I155660961 |
| authorships[10].institutions[0].country_code | FI |
| authorships[10].institutions[0].display_name | University of Turku |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Himanshu Kumar |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Functional Foods Forum, University of Turku, Turku, Finland |
| authorships[11].author.id | https://openalex.org/A5038766435 |
| authorships[11].author.orcid | https://orcid.org/0000-0003-2265-2280 |
| authorships[11].author.display_name | Helena Ollila |
| authorships[11].countries | FI |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I155660961 |
| authorships[11].affiliations[0].raw_affiliation_string | Department of Biostatistics, Faculty of Medicine, University of Turku, Turku, Finland |
| authorships[11].institutions[0].id | https://openalex.org/I155660961 |
| authorships[11].institutions[0].ror | https://ror.org/05vghhr25 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I155660961 |
| authorships[11].institutions[0].country_code | FI |
| authorships[11].institutions[0].display_name | University of Turku |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Helena Ollila |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Department of Biostatistics, Faculty of Medicine, University of Turku, Turku, Finland |
| authorships[12].author.id | https://openalex.org/A5079774398 |
| authorships[12].author.orcid | |
| authorships[12].author.display_name | Anne Kaljonen |
| authorships[12].countries | FI |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I155660961 |
| authorships[12].affiliations[0].raw_affiliation_string | Department of Biostatistics, Faculty of Medicine, University of Turku, Turku, Finland |
| authorships[12].institutions[0].id | https://openalex.org/I155660961 |
| authorships[12].institutions[0].ror | https://ror.org/05vghhr25 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I155660961 |
| authorships[12].institutions[0].country_code | FI |
| authorships[12].institutions[0].display_name | University of Turku |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Anne Kaljonen |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Department of Biostatistics, Faculty of Medicine, University of Turku, Turku, Finland |
| authorships[13].author.id | https://openalex.org/A5050767971 |
| authorships[13].author.orcid | https://orcid.org/0000-0002-1635-8002 |
| authorships[13].author.display_name | Erika Isolauri |
| authorships[13].countries | FI |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I155660961, https://openalex.org/I2801970007 |
| authorships[13].affiliations[0].raw_affiliation_string | Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[13].institutions[0].id | https://openalex.org/I2801970007 |
| authorships[13].institutions[0].ror | https://ror.org/05dbzj528 |
| authorships[13].institutions[0].type | healthcare |
| authorships[13].institutions[0].lineage | https://openalex.org/I2801970007, https://openalex.org/I4210127022 |
| authorships[13].institutions[0].country_code | FI |
| authorships[13].institutions[0].display_name | Turku University Hospital |
| authorships[13].institutions[1].id | https://openalex.org/I155660961 |
| authorships[13].institutions[1].ror | https://ror.org/05vghhr25 |
| authorships[13].institutions[1].type | education |
| authorships[13].institutions[1].lineage | https://openalex.org/I155660961 |
| authorships[13].institutions[1].country_code | FI |
| authorships[13].institutions[1].display_name | University of Turku |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Erika Isolauri |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[14].author.id | https://openalex.org/A5072093984 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-9737-7642 |
| authorships[14].author.display_name | Seppo Salminen |
| authorships[14].countries | FI |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I155660961 |
| authorships[14].affiliations[0].raw_affiliation_string | Functional Foods Forum, University of Turku, Turku, Finland |
| authorships[14].institutions[0].id | https://openalex.org/I155660961 |
| authorships[14].institutions[0].ror | https://ror.org/05vghhr25 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I155660961 |
| authorships[14].institutions[0].country_code | FI |
| authorships[14].institutions[0].display_name | University of Turku |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Seppo Salminen |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Functional Foods Forum, University of Turku, Turku, Finland |
| authorships[15].author.id | https://openalex.org/A5013753273 |
| authorships[15].author.orcid | https://orcid.org/0000-0002-5069-6582 |
| authorships[15].author.display_name | Hanna Lagström |
| authorships[15].countries | FI |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I155660961, https://openalex.org/I2801970007 |
| authorships[15].affiliations[0].raw_affiliation_string | Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[15].institutions[0].id | https://openalex.org/I2801970007 |
| authorships[15].institutions[0].ror | https://ror.org/05dbzj528 |
| authorships[15].institutions[0].type | healthcare |
| authorships[15].institutions[0].lineage | https://openalex.org/I2801970007, https://openalex.org/I4210127022 |
| authorships[15].institutions[0].country_code | FI |
| authorships[15].institutions[0].display_name | Turku University Hospital |
| authorships[15].institutions[1].id | https://openalex.org/I155660961 |
| authorships[15].institutions[1].ror | https://ror.org/05vghhr25 |
| authorships[15].institutions[1].type | education |
| authorships[15].institutions[1].lineage | https://openalex.org/I155660961 |
| authorships[15].institutions[1].country_code | FI |
| authorships[15].institutions[1].display_name | University of Turku |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Hanna Lagström |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland |
| authorships[16].author.id | https://openalex.org/A5068576885 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-1583-5794 |
| authorships[16].author.display_name | Nicola Segata |
| authorships[16].countries | IT |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I193223587 |
| authorships[16].affiliations[0].raw_affiliation_string | Department CIBIO, University of Trento, Trento, Italy |
| authorships[16].institutions[0].id | https://openalex.org/I193223587 |
| authorships[16].institutions[0].ror | https://ror.org/05trd4x28 |
| authorships[16].institutions[0].type | education |
| authorships[16].institutions[0].lineage | https://openalex.org/I193223587 |
| authorships[16].institutions[0].country_code | IT |
| authorships[16].institutions[0].display_name | University of Trento |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Nicola Segata |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Department CIBIO, University of Trento, Trento, Italy |
| authorships[17].author.id | https://openalex.org/A5043357459 |
| authorships[17].author.orcid | https://orcid.org/0000-0003-0705-2316 |
| authorships[17].author.display_name | Itai Sharon |
| authorships[17].countries | IL |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I4210145032 |
| authorships[17].affiliations[0].raw_affiliation_string | Migal – Galilee Research Institute, Qiryat Shemona, Israel |
| authorships[17].institutions[0].id | https://openalex.org/I4210145032 |
| authorships[17].institutions[0].ror | https://ror.org/04kaqnt29 |
| authorships[17].institutions[0].type | facility |
| authorships[17].institutions[0].lineage | https://openalex.org/I4210145032 |
| authorships[17].institutions[0].country_code | IL |
| authorships[17].institutions[0].display_name | Migal - Galilee Technology Center |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Itai Sharon |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Migal – Galilee Research Institute, Qiryat Shemona, Israel |
| authorships[18].author.id | https://openalex.org/A5083239943 |
| authorships[18].author.orcid | https://orcid.org/0000-0003-1714-6148 |
| authorships[18].author.display_name | Yoram Louzoun |
| authorships[18].countries | IL |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[18].affiliations[0].raw_affiliation_string | Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel |
| authorships[18].institutions[0].id | https://openalex.org/I13955877 |
| authorships[18].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[18].institutions[0].type | education |
| authorships[18].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[18].institutions[0].country_code | IL |
| authorships[18].institutions[0].display_name | Bar-Ilan University |
| authorships[18].author_position | middle |
| authorships[18].raw_author_name | Yoram Louzoun |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel |
| authorships[19].author.id | https://openalex.org/A5039938217 |
| authorships[19].author.orcid | https://orcid.org/0000-0002-2420-6850 |
| authorships[19].author.display_name | Regina Ensenauer |
| authorships[19].countries | DE |
| authorships[19].affiliations[0].institution_ids | https://openalex.org/I44260953 |
| authorships[19].affiliations[0].raw_affiliation_string | Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children’s Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany |
| authorships[19].institutions[0].id | https://openalex.org/I44260953 |
| authorships[19].institutions[0].ror | https://ror.org/024z2rq82 |
| authorships[19].institutions[0].type | education |
| authorships[19].institutions[0].lineage | https://openalex.org/I44260953 |
| authorships[19].institutions[0].country_code | DE |
| authorships[19].institutions[0].display_name | Heinrich Heine University Düsseldorf |
| authorships[19].author_position | middle |
| authorships[19].raw_author_name | Regina Ensenauer |
| authorships[19].is_corresponding | False |
| authorships[19].raw_affiliation_strings | Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children’s Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany |
| authorships[20].author.id | https://openalex.org/A5015904288 |
| authorships[20].author.orcid | https://orcid.org/0000-0003-0935-3593 |
| authorships[20].author.display_name | Samuli Rautava |
| authorships[20].countries | FI |
| authorships[20].affiliations[0].institution_ids | https://openalex.org/I133731052, https://openalex.org/I2800394112 |
| authorships[20].affiliations[0].raw_affiliation_string | University of Helsinki & Helsinki University Hospital, New Children’s Hospital, Pediatric Research Center, Helsinki, Finland |
| authorships[20].institutions[0].id | https://openalex.org/I2800394112 |
| authorships[20].institutions[0].ror | https://ror.org/02e8hzf44 |
| authorships[20].institutions[0].type | healthcare |
| authorships[20].institutions[0].lineage | https://openalex.org/I2800394112, https://openalex.org/I4210166427 |
| authorships[20].institutions[0].country_code | FI |
| authorships[20].institutions[0].display_name | Helsinki University Hospital |
| authorships[20].institutions[1].id | https://openalex.org/I133731052 |
| authorships[20].institutions[1].ror | https://ror.org/040af2s02 |
| authorships[20].institutions[1].type | education |
| authorships[20].institutions[1].lineage | https://openalex.org/I133731052 |
| authorships[20].institutions[1].country_code | FI |
| authorships[20].institutions[1].display_name | University of Helsinki |
| authorships[20].author_position | middle |
| authorships[20].raw_author_name | Samuli Rautava |
| authorships[20].is_corresponding | True |
| authorships[20].raw_affiliation_strings | University of Helsinki & Helsinki University Hospital, New Children’s Hospital, Pediatric Research Center, Helsinki, Finland |
| authorships[21].author.id | https://openalex.org/A5018377158 |
| authorships[21].author.orcid | https://orcid.org/0000-0002-7738-1337 |
| authorships[21].author.display_name | Omry Koren |
| authorships[21].countries | IL |
| authorships[21].affiliations[0].institution_ids | https://openalex.org/I13955877 |
| authorships[21].affiliations[0].raw_affiliation_string | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| authorships[21].institutions[0].id | https://openalex.org/I13955877 |
| authorships[21].institutions[0].ror | https://ror.org/03kgsv495 |
| authorships[21].institutions[0].type | education |
| authorships[21].institutions[0].lineage | https://openalex.org/I13955877 |
| authorships[21].institutions[0].country_code | IL |
| authorships[21].institutions[0].display_name | Bar-Ilan University |
| authorships[21].author_position | last |
| authorships[21].raw_author_name | Omry Koren |
| authorships[21].is_corresponding | False |
| authorships[21].raw_affiliation_strings | Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.nature.com/articles/s41467-020-20495-4.pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Neonatal antibiotic exposure impairs child growth during the first six years of life by perturbing intestinal microbial colonization |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10066 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9994000196456909 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | Gut microbiota and health |
| related_works | https://openalex.org/W2994176440, https://openalex.org/W2510575233, https://openalex.org/W2481749367, https://openalex.org/W830718730, https://openalex.org/W2320108978, https://openalex.org/W2495367848, https://openalex.org/W2604155846, https://openalex.org/W2793477322, https://openalex.org/W4390658901, https://openalex.org/W2760047697 |
| cited_by_count | 200 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 30 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 61 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 42 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 31 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 36 |
| locations_count | 6 |
| best_oa_location.id | doi:10.1038/s41467-020-20495-4 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S64187185 |
| best_oa_location.source.issn | 2041-1723 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2041-1723 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Nature Communications |
| best_oa_location.source.host_organization | https://openalex.org/P4310319908 |
| best_oa_location.source.host_organization_name | Nature Portfolio |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310319908 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.nature.com/articles/s41467-020-20495-4.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Nature Communications |
| best_oa_location.landing_page_url | https://doi.org/10.1038/s41467-020-20495-4 |
| primary_location.id | doi:10.1038/s41467-020-20495-4 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S64187185 |
| primary_location.source.issn | 2041-1723 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2041-1723 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Nature Communications |
| primary_location.source.host_organization | https://openalex.org/P4310319908 |
| primary_location.source.host_organization_name | Nature Portfolio |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310319908 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.nature.com/articles/s41467-020-20495-4.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Nature Communications |
| primary_location.landing_page_url | https://doi.org/10.1038/s41467-020-20495-4 |
| publication_date | 2021-01-26 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2557713955, https://openalex.org/W2896652973, https://openalex.org/W1981972563, https://openalex.org/W2412200876, https://openalex.org/W2035467636, https://openalex.org/W1993399595, https://openalex.org/W2041136224, https://openalex.org/W2004326296, https://openalex.org/W2098986577, https://openalex.org/W2053039168, https://openalex.org/W2575984858, https://openalex.org/W2322471302, https://openalex.org/W2944140387, https://openalex.org/W2883219978, https://openalex.org/W2142037839, https://openalex.org/W2899423833, https://openalex.org/W1978695620, https://openalex.org/W2060741641, https://openalex.org/W2167062509, https://openalex.org/W2149515881, https://openalex.org/W2042855997, https://openalex.org/W2110189329, https://openalex.org/W2125031539, https://openalex.org/W2904950674, https://openalex.org/W2310604907, https://openalex.org/W2896488357, https://openalex.org/W1945327512, https://openalex.org/W2287246374, https://openalex.org/W2174019968, https://openalex.org/W2143196592, https://openalex.org/W2896617742, https://openalex.org/W2896481903, https://openalex.org/W2153197171, https://openalex.org/W1976335360, https://openalex.org/W2526654904, https://openalex.org/W2126778875, https://openalex.org/W2888319175, https://openalex.org/W2796515368, https://openalex.org/W2116533117, https://openalex.org/W1965959506, https://openalex.org/W2166171121, https://openalex.org/W2897204056, https://openalex.org/W2401404581, https://openalex.org/W1988925586, https://openalex.org/W2166655850, https://openalex.org/W2170024099, https://openalex.org/W2768716840, https://openalex.org/W2913398748, https://openalex.org/W2131271579, https://openalex.org/W2145537580, https://openalex.org/W2055043387, https://openalex.org/W2414977535, https://openalex.org/W2336584083, https://openalex.org/W2963276645, https://openalex.org/W2089515755 |
| referenced_works_count | 55 |
| abstract_inverted_index.2 | 137 |
| abstract_inverted_index.6 | 63, 94 |
| abstract_inverted_index.a | 173 |
| abstract_inverted_index.In | 82 |
| abstract_inverted_index.We | 51 |
| abstract_inverted_index.an | 40 |
| abstract_inverted_index.at | 48 |
| abstract_inverted_index.in | 4, 29, 39, 71, 75, 110, 123, 128, 159, 181, 184, 197 |
| abstract_inverted_index.is | 10, 98, 118, 170, 199 |
| abstract_inverted_index.of | 8, 17, 26, 44, 55, 65, 96, 133, 139, 191 |
| abstract_inverted_index.on | 36 |
| abstract_inverted_index.to | 2, 12, 151 |
| abstract_inverted_index.we | 21, 142, 164 |
| abstract_inverted_index.and | 33, 57, 113, 131, 178 |
| abstract_inverted_index.but | 73, 90, 154 |
| abstract_inverted_index.for | 79 |
| abstract_inverted_index.gut | 125, 175 |
| abstract_inverted_index.may | 179 |
| abstract_inverted_index.not | 74, 155 |
| abstract_inverted_index.six | 189 |
| abstract_inverted_index.the | 5, 23, 30, 61, 87, 92, 107, 124, 187 |
| abstract_inverted_index.use | 85, 195 |
| abstract_inverted_index.age. | 140 |
| abstract_inverted_index.body | 103, 203 |
| abstract_inverted_index.born | 47 |
| abstract_inverted_index.both | 111 |
| abstract_inverted_index.boys | 112, 185 |
| abstract_inverted_index.days | 7 |
| abstract_inverted_index.find | 52 |
| abstract_inverted_index.from | 148 |
| abstract_inverted_index.full | 49 |
| abstract_inverted_index.gain | 59 |
| abstract_inverted_index.life | 9, 66, 97, 192 |
| abstract_inverted_index.mass | 104, 204 |
| abstract_inverted_index.mice | 157 |
| abstract_inverted_index.that | 144, 166 |
| abstract_inverted_index.with | 100, 120, 172, 201 |
| abstract_inverted_index.Here, | 20 |
| abstract_inverted_index.Thus, | 163 |
| abstract_inverted_index.after | 67, 77, 86 |
| abstract_inverted_index.birth | 42 |
| abstract_inverted_index.boys, | 72 |
| abstract_inverted_index.child | 37 |
| abstract_inverted_index.early | 34 |
| abstract_inverted_index.fecal | 134, 145 |
| abstract_inverted_index.first | 6, 62, 93, 188 |
| abstract_inverted_index.index | 105 |
| abstract_inverted_index.later | 196 |
| abstract_inverted_index.male, | 153 |
| abstract_inverted_index.study | 108 |
| abstract_inverted_index.term. | 50 |
| abstract_inverted_index.until | 136 |
| abstract_inverted_index.while | 193 |
| abstract_inverted_index.years | 64, 95, 138, 190 |
| abstract_inverted_index.12,422 | 45 |
| abstract_inverted_index.affect | 13 |
| abstract_inverted_index.cohort | 43 |
| abstract_inverted_index.during | 60, 91, 186 |
| abstract_inverted_index.girls, | 76 |
| abstract_inverted_index.girls. | 114 |
| abstract_inverted_index.growth | 38, 161, 183 |
| abstract_inverted_index.height | 58 |
| abstract_inverted_index.higher | 102 |
| abstract_inverted_index.impact | 25 |
| abstract_inverted_index.index. | 205 |
| abstract_inverted_index.period | 32, 89, 109 |
| abstract_inverted_index.result | 180 |
| abstract_inverted_index.weight | 56 |
| abstract_inverted_index.aspects | 16 |
| abstract_inverted_index.female, | 156 |
| abstract_inverted_index.reduced | 182 |
| abstract_inverted_index.results | 158 |
| abstract_inverted_index.thought | 11 |
| abstract_inverted_index.various | 14 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Exposure | 1 |
| abstract_inverted_index.Finally, | 141 |
| abstract_inverted_index.Neonatal | 115 |
| abstract_inverted_index.children | 46, 150 |
| abstract_inverted_index.conclude | 165 |
| abstract_inverted_index.exposure | 70, 117, 169 |
| abstract_inverted_index.neonatal | 18, 31, 68, 88, 167 |
| abstract_inverted_index.abundance | 130 |
| abstract_inverted_index.adjusting | 78 |
| abstract_inverted_index.childhood | 35, 198 |
| abstract_inverted_index.contrast, | 83 |
| abstract_inverted_index.decreased | 129 |
| abstract_inverted_index.diversity | 132 |
| abstract_inverted_index.germ-free | 152 |
| abstract_inverted_index.increased | 202 |
| abstract_inverted_index.long-term | 24, 174 |
| abstract_inverted_index.potential | 80 |
| abstract_inverted_index.treatment | 28 |
| abstract_inverted_index.antibiotic | 27, 69, 84, 116, 168, 194 |
| abstract_inverted_index.associated | 99, 119, 171, 200 |
| abstract_inverted_index.microbiome | 176 |
| abstract_inverted_index.microbiota | 146 |
| abstract_inverted_index.throughout | 106 |
| abstract_inverted_index.transplant | 147 |
| abstract_inverted_index.unselected | 41 |
| abstract_inverted_index.antibiotics | 3 |
| abstract_inverted_index.attenuation | 54 |
| abstract_inverted_index.demonstrate | 143 |
| abstract_inverted_index.differences | 122 |
| abstract_inverted_index.impairment. | 162 |
| abstract_inverted_index.investigate | 22 |
| abstract_inverted_index.microbiome, | 126 |
| abstract_inverted_index.significant | 53, 121, 160 |
| abstract_inverted_index.confounders. | 81 |
| abstract_inverted_index.development. | 19 |
| abstract_inverted_index.particularly | 127 |
| abstract_inverted_index.perturbation | 177 |
| abstract_inverted_index.physiological | 15 |
| abstract_inverted_index.significantly | 101 |
| abstract_inverted_index.Bifidobacteria | 135 |
| abstract_inverted_index.antibiotic-exposed | 149 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 99 |
| corresponding_author_ids | https://openalex.org/A5015904288 |
| countries_distinct_count | 4 |
| institutions_distinct_count | 22 |
| corresponding_institution_ids | https://openalex.org/I133731052, https://openalex.org/I2800394112 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.5799999833106995 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.99491241 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |