Neurological and Mental Health Symptoms Associated with Post-COVID-19 Disability in a Sample of Patients Discharged from a COVID-19 Ward: A Secondary Analysis Article Swipe
Martina Cacciatore
,
Alberto Raggi
,
Andrea Pilotto
,
Viviana Cristillo
,
Erika Guastafierro
,
Claudia Toppo
,
Francesca Giulia Magnani
,
Davide Sattin
,
Arianna Mariniello
,
Fabiola Silvaggi
,
Stefano Cotti Piccinelli
,
Nicola Zoppi
,
Giulio Bonzi
,
Stefano Gipponi
,
Ilenia Libri
,
Michela Bezzi
,
Paolo Martelletti
,
Matilde Leonardi
,
Alessandro Padovani
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/ijerph19074242
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/ijerph19074242
Recent studies suggest that COVID-19 survivors may experience long-term health consequences: in particular, neurological and mental health symptoms might be associated with long-term negative outcomes. This study is a secondary analysis of a larger cohort study and aims to determine the extent to which neurological and mental health sequelae are associated with survivors’ disability. Participants include COVID-19 survivors, with no pre-morbid brain conditions, who were discharged from the COVID-19 Unit of the ASST Spedali Civili Hospital between February and April 2020. At an average of 3.5 months after discharge, they were submitted to a neurological examination and completed the WHO Disability Assessment Schedule (WHODAS-12), the Hospital Anxiety and Depression Score, the Pittsburgh Sleep Quality Index and the Montreal Cognitive Assessment. Multivariable regression analysis was carried out to analyze variables that explain WHODAS-12 variation. In total, 83 patients (63 males, average age 66.9, 95% CI: 64.2–69.7) were enrolled; average WHODAS-12 was 13.2 (95% CI: 9.7–16.6). Cognitive dysfunction, anxiety, fatigue, and hyposmia/hypogeusia explained 28.8% of WHODAS-12 variation. These findings underline the importance and need for longitudinal follow-up assessments after recovery from COVID-19 and suggest the need for early rehabilitation of residual symptoms to enhance patients’ functioning.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/ijerph19074242
- https://www.mdpi.com/1660-4601/19/7/4242/pdf?version=1648871303
- OA Status
- gold
- Cited By
- 30
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4223494310
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4223494310Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/ijerph19074242Digital Object Identifier
- Title
-
Neurological and Mental Health Symptoms Associated with Post-COVID-19 Disability in a Sample of Patients Discharged from a COVID-19 Ward: A Secondary AnalysisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-04-02Full publication date if available
- Authors
-
Martina Cacciatore, Alberto Raggi, Andrea Pilotto, Viviana Cristillo, Erika Guastafierro, Claudia Toppo, Francesca Giulia Magnani, Davide Sattin, Arianna Mariniello, Fabiola Silvaggi, Stefano Cotti Piccinelli, Nicola Zoppi, Giulio Bonzi, Stefano Gipponi, Ilenia Libri, Michela Bezzi, Paolo Martelletti, Matilde Leonardi, Alessandro PadovaniList of authors in order
- Landing page
-
https://doi.org/10.3390/ijerph19074242Publisher landing page
- PDF URL
-
https://www.mdpi.com/1660-4601/19/7/4242/pdf?version=1648871303Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/1660-4601/19/7/4242/pdf?version=1648871303Direct OA link when available
- Concepts
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Medicine, Anxiety, Depression (economics), Mental health, Cohort, Cohort study, Psychiatry, Physical therapy, Pediatrics, Internal medicine, Economics, MacroeconomicsTop concepts (fields/topics) attached by OpenAlex
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30Total citation count in OpenAlex
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2025: 6, 2024: 10, 2023: 10, 2022: 4Per-year citation counts (last 5 years)
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55Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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