Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources Article Swipe
Yating Liu
,
Guojing Tian
,
Ziyi Wang
,
Junkang Zheng
,
Huimin Liu
,
S. H. Zhu
,
Zhao Shan
,
Bin Qi
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.7554/elife.104028.2
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.7554/elife.104028.2
The ability to sense and adapt to adverse food conditions is essential for survival across species, but the detailed mechanisms of neuron-digestive crosstalk in food sensing and adaptation remain poorly understood. This study identifies a novel mechanism by which animals detect unfavorable food sources through neurons and initiate a systemic response to shut down digestion, thus safeguarding against potential harm. Specifically, we demonstrate that NSY-1, expressed in AWC neurons, detects Staphylococcus saprophyticus (SS) as an unfavorable food source, prompting the animal to avoid and halt digestion of SS. Upon detection, the animals activate the AWCOFF neural circuit, leading to a systemic digestive shutdown, which is mediated by NSY-1-dependent STR-130. Additionally, NSY-1 mutation triggers the production of insulin peptides, including INS-23, which interact with the DAF-2 receptor to modulate SS digestion and affects the expression of intestinal BCF-1. These findings uncover a crucial survival strategy through neuron-digestive crosstalk, where the NSY-1 pathway in AWC neurons orchestrates food evaluation and initiates digestive shutdown to adapt effectively to harmful food sources.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.7554/elife.104028.2
- OA Status
- gold
- References
- 39
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413881495
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4413881495Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.7554/elife.104028.2Digital Object Identifier
- Title
-
Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food SourcesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-09-01Full publication date if available
- Authors
-
Yating Liu, Guojing Tian, Ziyi Wang, Junkang Zheng, Huimin Liu, S. H. Zhu, Zhao Shan, Bin QiList of authors in order
- Landing page
-
https://doi.org/10.7554/elife.104028.2Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.7554/elife.104028.2Direct OA link when available
- Concepts
-
Shutdown, Systemic risk, Engineering, Economics, Nuclear engineering, Macroeconomics, Financial crisisTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
39Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4413881495 |
|---|---|
| doi | https://doi.org/10.7554/elife.104028.2 |
| ids.doi | https://doi.org/10.7554/elife.104028.2 |
| ids.openalex | https://openalex.org/W4413881495 |
| fwci | 0.0 |
| type | article |
| title | Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T10971 |
| topics[0].field.id | https://openalex.org/fields/28 |
| topics[0].field.display_name | Neuroscience |
| topics[0].score | 0.9781000018119812 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2809 |
| topics[0].subfield.display_name | Sensory Systems |
| topics[0].display_name | Olfactory and Sensory Function Studies |
| topics[1].id | https://openalex.org/T12267 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9675999879837036 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2737 |
| topics[1].subfield.display_name | Physiology |
| topics[1].display_name | Diet and metabolism studies |
| topics[2].id | https://openalex.org/T10676 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9627000093460083 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1302 |
| topics[2].subfield.display_name | Aging |
| topics[2].display_name | Genetics, Aging, and Longevity in Model Organisms |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2780263472 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8710005283355713 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q331902 |
| concepts[0].display_name | Shutdown |
| concepts[1].id | https://openalex.org/C144587487 |
| concepts[1].level | 3 |
| concepts[1].score | 0.5287137627601624 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1369234 |
| concepts[1].display_name | Systemic risk |
| concepts[2].id | https://openalex.org/C127413603 |
| concepts[2].level | 0 |
| concepts[2].score | 0.10388672351837158 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[2].display_name | Engineering |
| concepts[3].id | https://openalex.org/C162324750 |
| concepts[3].level | 0 |
| concepts[3].score | 0.09314402937889099 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q8134 |
| concepts[3].display_name | Economics |
| concepts[4].id | https://openalex.org/C116915560 |
| concepts[4].level | 1 |
| concepts[4].score | 0.09194523096084595 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q83504 |
| concepts[4].display_name | Nuclear engineering |
| concepts[5].id | https://openalex.org/C139719470 |
| concepts[5].level | 1 |
| concepts[5].score | 0.0 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q39680 |
| concepts[5].display_name | Macroeconomics |
| concepts[6].id | https://openalex.org/C2778300220 |
| concepts[6].level | 2 |
| concepts[6].score | 0.0 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q114380 |
| concepts[6].display_name | Financial crisis |
| keywords[0].id | https://openalex.org/keywords/shutdown |
| keywords[0].score | 0.8710005283355713 |
| keywords[0].display_name | Shutdown |
| keywords[1].id | https://openalex.org/keywords/systemic-risk |
| keywords[1].score | 0.5287137627601624 |
| keywords[1].display_name | Systemic risk |
| keywords[2].id | https://openalex.org/keywords/engineering |
| keywords[2].score | 0.10388672351837158 |
| keywords[2].display_name | Engineering |
| keywords[3].id | https://openalex.org/keywords/economics |
| keywords[3].score | 0.09314402937889099 |
| keywords[3].display_name | Economics |
| keywords[4].id | https://openalex.org/keywords/nuclear-engineering |
| keywords[4].score | 0.09194523096084595 |
| keywords[4].display_name | Nuclear engineering |
| language | en |
| locations[0].id | doi:10.7554/elife.104028.2 |
| locations[0].is_oa | True |
| locations[0].source | |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | acceptedVersion |
| locations[0].raw_type | posted-content |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | False |
| locations[0].raw_source_name | |
| locations[0].landing_page_url | https://doi.org/10.7554/elife.104028.2 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5100727177 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-5256-1331 |
| authorships[0].author.display_name | Yating Liu |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[0].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[0].institutions[0].id | https://openalex.org/I189210763 |
| authorships[0].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Yunnan University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Yating Liu |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[1].author.id | https://openalex.org/A5079075087 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-5702-1142 |
| authorships[1].author.display_name | Guojing Tian |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[1].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[1].institutions[0].id | https://openalex.org/I189210763 |
| authorships[1].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Yunnan University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Guojing Tian |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[2].author.id | https://openalex.org/A5100441389 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4410-6889 |
| authorships[2].author.display_name | Ziyi Wang |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[2].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[2].institutions[0].id | https://openalex.org/I189210763 |
| authorships[2].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Yunnan University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Ziyi Wang |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[3].author.id | https://openalex.org/A5074279758 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Junkang Zheng |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[3].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[3].institutions[0].id | https://openalex.org/I189210763 |
| authorships[3].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Yunnan University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Junkang Zheng |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[4].author.id | https://openalex.org/A5100329507 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-2265-2961 |
| authorships[4].author.display_name | Huimin Liu |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[4].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[4].institutions[0].id | https://openalex.org/I189210763 |
| authorships[4].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Yunnan University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Huimin Liu |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[5].author.id | https://openalex.org/A5106732668 |
| authorships[5].author.orcid | https://orcid.org/0009-0007-4479-1093 |
| authorships[5].author.display_name | S. H. Zhu |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[5].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[5].institutions[0].id | https://openalex.org/I189210763 |
| authorships[5].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Yunnan University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Sucheng Zhu |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[6].author.id | https://openalex.org/A5077703539 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-5064-1023 |
| authorships[6].author.display_name | Zhao Shan |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[6].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[6].institutions[0].id | https://openalex.org/I189210763 |
| authorships[6].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | Yunnan University |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Zhao Shan |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[7].author.id | https://openalex.org/A5049675505 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-2261-1550 |
| authorships[7].author.display_name | Bin Qi |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I189210763 |
| authorships[7].affiliations[0].raw_affiliation_string | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| authorships[7].institutions[0].id | https://openalex.org/I189210763 |
| authorships[7].institutions[0].ror | https://ror.org/0040axw97 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I189210763 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Yunnan University |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Bin Qi |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, School of Life Sciences, Yunnan University |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.7554/elife.104028.2 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-25T14:43:58.451035 |
| primary_topic.id | https://openalex.org/T10971 |
| primary_topic.field.id | https://openalex.org/fields/28 |
| primary_topic.field.display_name | Neuroscience |
| primary_topic.score | 0.9781000018119812 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2809 |
| primary_topic.subfield.display_name | Sensory Systems |
| primary_topic.display_name | Olfactory and Sensory Function Studies |
| related_works | https://openalex.org/W284773248, https://openalex.org/W3021445509, https://openalex.org/W2387852758, https://openalex.org/W4243903966, https://openalex.org/W4242784450, https://openalex.org/W2341076016, https://openalex.org/W2374473947, https://openalex.org/W1603859412, https://openalex.org/W311515923, https://openalex.org/W2051172214 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.7554/elife.104028.2 |
| best_oa_location.is_oa | True |
| best_oa_location.source | |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | acceptedVersion |
| best_oa_location.raw_type | posted-content |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | |
| best_oa_location.landing_page_url | https://doi.org/10.7554/elife.104028.2 |
| primary_location.id | doi:10.7554/elife.104028.2 |
| primary_location.is_oa | True |
| primary_location.source | |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | acceptedVersion |
| primary_location.raw_type | posted-content |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | False |
| primary_location.raw_source_name | |
| primary_location.landing_page_url | https://doi.org/10.7554/elife.104028.2 |
| publication_date | 2025-09-01 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W3115110895, https://openalex.org/W2064416689, https://openalex.org/W2166222890, https://openalex.org/W2097186487, https://openalex.org/W2149028037, https://openalex.org/W2088851910, https://openalex.org/W2013152912, https://openalex.org/W2060297895, https://openalex.org/W2155000552, https://openalex.org/W2008406421, https://openalex.org/W4384072197, https://openalex.org/W3118854353, https://openalex.org/W4294275322, https://openalex.org/W4394841412, https://openalex.org/W4317498964, https://openalex.org/W2164646000, https://openalex.org/W2738112734, https://openalex.org/W2169965375, https://openalex.org/W2104818214, https://openalex.org/W2052722944, https://openalex.org/W2137395936, https://openalex.org/W4313545433, https://openalex.org/W4391130261, https://openalex.org/W2782441310, https://openalex.org/W4293835557, https://openalex.org/W4384025425, https://openalex.org/W2620966823, https://openalex.org/W2809651623, https://openalex.org/W2121039111, https://openalex.org/W2433871124, https://openalex.org/W2611331868, https://openalex.org/W2782996711, https://openalex.org/W2148211715, https://openalex.org/W2022221238, https://openalex.org/W2113585283, https://openalex.org/W2118509956, https://openalex.org/W2775621606, https://openalex.org/W1526941437, https://openalex.org/W1965404074 |
| referenced_works_count | 39 |
| abstract_inverted_index.a | 35, 49, 100, 141 |
| abstract_inverted_index.SS | 129 |
| abstract_inverted_index.an | 75 |
| abstract_inverted_index.as | 74 |
| abstract_inverted_index.by | 38, 107 |
| abstract_inverted_index.in | 24, 67, 152 |
| abstract_inverted_index.is | 11, 105 |
| abstract_inverted_index.of | 21, 87, 116, 135 |
| abstract_inverted_index.to | 3, 7, 52, 82, 99, 127, 162, 165 |
| abstract_inverted_index.we | 62 |
| abstract_inverted_index.AWC | 68, 153 |
| abstract_inverted_index.SS. | 88 |
| abstract_inverted_index.The | 1 |
| abstract_inverted_index.and | 5, 27, 47, 84, 131, 158 |
| abstract_inverted_index.but | 17 |
| abstract_inverted_index.for | 13 |
| abstract_inverted_index.the | 18, 80, 91, 94, 114, 124, 133, 149 |
| abstract_inverted_index.(SS) | 73 |
| abstract_inverted_index.This | 32 |
| abstract_inverted_index.Upon | 89 |
| abstract_inverted_index.down | 54 |
| abstract_inverted_index.food | 9, 25, 43, 77, 156, 167 |
| abstract_inverted_index.halt | 85 |
| abstract_inverted_index.shut | 53 |
| abstract_inverted_index.that | 64 |
| abstract_inverted_index.thus | 56 |
| abstract_inverted_index.with | 123 |
| abstract_inverted_index.DAF-2 | 125 |
| abstract_inverted_index.NSY-1 | 111, 150 |
| abstract_inverted_index.These | 138 |
| abstract_inverted_index.adapt | 6, 163 |
| abstract_inverted_index.avoid | 83 |
| abstract_inverted_index.harm. | 60 |
| abstract_inverted_index.novel | 36 |
| abstract_inverted_index.sense | 4 |
| abstract_inverted_index.study | 33 |
| abstract_inverted_index.where | 148 |
| abstract_inverted_index.which | 39, 104, 121 |
| abstract_inverted_index.AWCOFF | 95 |
| abstract_inverted_index.BCF-1. | 137 |
| abstract_inverted_index.NSY-1, | 65 |
| abstract_inverted_index.across | 15 |
| abstract_inverted_index.animal | 81 |
| abstract_inverted_index.detect | 41 |
| abstract_inverted_index.neural | 96 |
| abstract_inverted_index.poorly | 30 |
| abstract_inverted_index.remain | 29 |
| abstract_inverted_index.INS-23, | 120 |
| abstract_inverted_index.ability | 2 |
| abstract_inverted_index.adverse | 8 |
| abstract_inverted_index.affects | 132 |
| abstract_inverted_index.against | 58 |
| abstract_inverted_index.animals | 40, 92 |
| abstract_inverted_index.crucial | 142 |
| abstract_inverted_index.detects | 70 |
| abstract_inverted_index.harmful | 166 |
| abstract_inverted_index.insulin | 117 |
| abstract_inverted_index.leading | 98 |
| abstract_inverted_index.neurons | 46, 154 |
| abstract_inverted_index.pathway | 151 |
| abstract_inverted_index.sensing | 26 |
| abstract_inverted_index.source, | 78 |
| abstract_inverted_index.sources | 44 |
| abstract_inverted_index.through | 45, 145 |
| abstract_inverted_index.uncover | 140 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.STR-130. | 109 |
| abstract_inverted_index.activate | 93 |
| abstract_inverted_index.circuit, | 97 |
| abstract_inverted_index.detailed | 19 |
| abstract_inverted_index.findings | 139 |
| abstract_inverted_index.initiate | 48 |
| abstract_inverted_index.interact | 122 |
| abstract_inverted_index.mediated | 106 |
| abstract_inverted_index.modulate | 128 |
| abstract_inverted_index.mutation | 112 |
| abstract_inverted_index.neurons, | 69 |
| abstract_inverted_index.receptor | 126 |
| abstract_inverted_index.response | 51 |
| abstract_inverted_index.shutdown | 161 |
| abstract_inverted_index.sources. | 168 |
| abstract_inverted_index.species, | 16 |
| abstract_inverted_index.strategy | 144 |
| abstract_inverted_index.survival | 14, 143 |
| abstract_inverted_index.systemic | 50, 101 |
| abstract_inverted_index.triggers | 113 |
| abstract_inverted_index.crosstalk | 23 |
| abstract_inverted_index.digestion | 86, 130 |
| abstract_inverted_index.digestive | 102, 160 |
| abstract_inverted_index.essential | 12 |
| abstract_inverted_index.expressed | 66 |
| abstract_inverted_index.including | 119 |
| abstract_inverted_index.initiates | 159 |
| abstract_inverted_index.mechanism | 37 |
| abstract_inverted_index.peptides, | 118 |
| abstract_inverted_index.potential | 59 |
| abstract_inverted_index.prompting | 79 |
| abstract_inverted_index.shutdown, | 103 |
| abstract_inverted_index.adaptation | 28 |
| abstract_inverted_index.conditions | 10 |
| abstract_inverted_index.crosstalk, | 147 |
| abstract_inverted_index.detection, | 90 |
| abstract_inverted_index.digestion, | 55 |
| abstract_inverted_index.evaluation | 157 |
| abstract_inverted_index.expression | 134 |
| abstract_inverted_index.identifies | 34 |
| abstract_inverted_index.intestinal | 136 |
| abstract_inverted_index.mechanisms | 20 |
| abstract_inverted_index.production | 115 |
| abstract_inverted_index.demonstrate | 63 |
| abstract_inverted_index.effectively | 164 |
| abstract_inverted_index.understood. | 31 |
| abstract_inverted_index.unfavorable | 42, 76 |
| abstract_inverted_index.orchestrates | 155 |
| abstract_inverted_index.safeguarding | 57 |
| abstract_inverted_index.Additionally, | 110 |
| abstract_inverted_index.Specifically, | 61 |
| abstract_inverted_index.saprophyticus | 72 |
| abstract_inverted_index.Staphylococcus | 71 |
| abstract_inverted_index.NSY-1-dependent | 108 |
| abstract_inverted_index.neuron-digestive | 22, 146 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 8 |
| citation_normalized_percentile.value | 0.41266753 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |