New insight in treating autoimmune diseases by targeting autophagy Article Swipe
Jiao Lyu
,
Hongqian Zhang
,
Chaoyang Wang
,
Mingyu Pan
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1080/08916934.2024.2351872
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1080/08916934.2024.2351872
Autophagy is a highly conserved biological process in eukaryotes, which degrades cellular misfolded proteins, damaged organelles and invasive pathogens in the lysosome-dependent manner. Autoimmune diseases caused by genetic elements, environments and aberrant immune responses severely impact patients' living quality and even threaten life. Recently, numerous studies have reported autophagy can regulate immune responses, and play an important role in autoimmune diseases. In this review, we summarised the features of autophagy and autophagy-related genes, enumerated some autophagy-related genes involved in autoimmune diseases, and further overviewed how to treat autoimmune diseases through targeting autophagy. Finally, we outlooked the prospect of relieving and curing autoimmune diseases by targeting autophagy pathway.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1080/08916934.2024.2351872
- https://www.tandfonline.com/doi/pdf/10.1080/08916934.2024.2351872?needAccess=true
- OA Status
- diamond
- Cited By
- 5
- References
- 201
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4396852845Canonical identifier for this work in OpenAlex
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https://doi.org/10.1080/08916934.2024.2351872Digital Object Identifier
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New insight in treating autoimmune diseases by targeting autophagyWork title
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reviewOpenAlex work type
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enPrimary language
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2024Year of publication
- Publication date
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2024-05-13Full publication date if available
- Authors
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Jiao Lyu, Hongqian Zhang, Chaoyang Wang, Mingyu PanList of authors in order
- Landing page
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https://doi.org/10.1080/08916934.2024.2351872Publisher landing page
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https://www.tandfonline.com/doi/pdf/10.1080/08916934.2024.2351872?needAccess=trueDirect link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://www.tandfonline.com/doi/pdf/10.1080/08916934.2024.2351872?needAccess=trueDirect OA link when available
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Autophagy, Autoimmune disease, Autoimmunity, Medicine, Immunology, Biology, Immune system, Antibody, Genetics, ApoptosisTop concepts (fields/topics) attached by OpenAlex
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5Total citation count in OpenAlex
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2025: 3, 2024: 2Per-year citation counts (last 5 years)
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201Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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