NGAP Data Analysis Protocol v1 Article Swipe

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Gordon Qian , Ryan Davis , Jennifer Johnston ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.17504/protocols.io.14egn614pl5d/v1

Protocol for processing and analysis of data in the Neuronal Genome Atlas for Parkinsons (NGAP) on Illumina Connected Analytics (ICA). The protocol details the processing of data through the germline and somatic variant call pipelines on ICA and custom analysis of cell line metrics (Parkinsons Polygenic Risk Score, Tumour Normal comparison of parent and daughter lines for somatic variation, Mitochondrial local constraint, Mitochondrial DNA copy number and ploidy of autosomes) for comparison between cell lines.

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Protocol (science) Computer science Medicine Pathology Alternative medicine

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Type: preprint
Language: en
Landing Page: https://doi.org/10.17504/protocols.io.14egn614pl5d/v1
PDF: https://www.protocols.io/view/ngap-data-analysis-protocol-dkip4udn.pdf
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DOI: https://doi.org/10.17504/protocols.io.14egn614pl5d/v1

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Title: NGAP Data Analysis Protocol v1

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Type: preprint

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Language: en

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Publication year: 2024

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Publication date: 2024-09-01

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Authors: Gordon Qian, Ryan Davis, Jennifer Johnston

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Landing page: https://doi.org/10.17504/protocols.io.14egn614pl5d/v1

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PDF URL: https://www.protocols.io/view/ngap-data-analysis-protocol-dkip4udn.pdf

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