Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging Article Swipe
Ken‐ichiro Matsumoto
,
Ikuo Nakanishi
,
Zhivko Zhelev
,
Rumiana Bakalova
,
Ichio Aoki
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1089/ars.2021.0110
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1089/ars.2021.0110
Significance: In vivo assessment of paramagnetic and diamagnetic conversions of nitroxyl radicals based on cyclic redox mechanism can be an index of tissue redox status. The redox mechanism of nitroxyl radicals, which enables their use as a normal tissue-selective radioprotector, is seen as being attractive on planning radiation therapy. Recent Advances: In vivo redox imaging using nitroxyl radicals as redox-sensitive contrast agents has been developed to assess tissue redox status. Chemical and biological behaviors depending on chemical structures of nitroxyl radical compounds have been understood in detail. Polymer types of nitroxyl radical contrast agents and/or nitroxyl radical-labeled drugs were designed for approaching theranostics. Critical Issues: Nitroxyl radicals as magnetic resonance imaging (MRI) contrast agents have several advantages compared with those used in electron paramagnetic resonance (EPR) imaging, while support by EPR spectroscopy is important to understand information from MRI. Redox-sensitive paramagnetic contrast agents having a medicinal benefit, that is, nitroxyl-labeled drug, have been developed and proposed. Future Directions: A development of suitable nitroxyl contrast agent for translational theranostic applications with high reaction specificity and low normal tissue toxicity is under progress. Nitroxyl radicals as redox-sensitive magnetic resonance contrast agents can be a useful tool to detect an abnormal tissue redox status such as disordered oxidative stress. Antioxid. Redox Signal. 36, 95–121.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1089/ars.2021.0110
- OA Status
- hybrid
- Cited By
- 28
- References
- 203
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3173969959
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3173969959Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1089/ars.2021.0110Digital Object Identifier
- Title
-
Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox ImagingWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-06-19Full publication date if available
- Authors
-
Ken‐ichiro Matsumoto, Ikuo Nakanishi, Zhivko Zhelev, Rumiana Bakalova, Ichio AokiList of authors in order
- Landing page
-
https://doi.org/10.1089/ars.2021.0110Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1089/ars.2021.0110Direct OA link when available
- Concepts
-
Nitroxyl, Redox, Chemistry, Electron paramagnetic resonance, Radical, MRI contrast agent, Photochemistry, Nuclear magnetic resonance, Gadolinium, Organic chemistry, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
28Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 14, 2023: 7, 2022: 2, 2021: 1Per-year citation counts (last 5 years)
- References (count)
-
203Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3173969959 |
|---|---|
| doi | https://doi.org/10.1089/ars.2021.0110 |
| ids.doi | https://doi.org/10.1089/ars.2021.0110 |
| ids.mag | 3173969959 |
| ids.openalex | https://openalex.org/W3173969959 |
| fwci | 3.49493285 |
| type | article |
| title | Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging |
| biblio.issue | 1-3 |
| biblio.volume | 36 |
| biblio.last_page | 121 |
| biblio.first_page | 95 |
| topics[0].id | https://openalex.org/T12381 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1304 |
| topics[0].subfield.display_name | Biophysics |
| topics[0].display_name | Electron Spin Resonance Studies |
| topics[1].id | https://openalex.org/T11279 |
| topics[1].field.id | https://openalex.org/fields/25 |
| topics[1].field.display_name | Materials Science |
| topics[1].score | 0.9998000264167786 |
| topics[1].domain.id | https://openalex.org/domains/3 |
| topics[1].domain.display_name | Physical Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2505 |
| topics[1].subfield.display_name | Materials Chemistry |
| topics[1].display_name | Lanthanide and Transition Metal Complexes |
| topics[2].id | https://openalex.org/T10612 |
| topics[2].field.id | https://openalex.org/fields/25 |
| topics[2].field.display_name | Materials Science |
| topics[2].score | 0.9979000091552734 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2504 |
| topics[2].subfield.display_name | Electronic, Optical and Magnetic Materials |
| topics[2].display_name | Magnetism in coordination complexes |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2776142628 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8844101428985596 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q2919470 |
| concepts[0].display_name | Nitroxyl |
| concepts[1].id | https://openalex.org/C55904794 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7606981992721558 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q82682 |
| concepts[1].display_name | Redox |
| concepts[2].id | https://openalex.org/C185592680 |
| concepts[2].level | 0 |
| concepts[2].score | 0.6745520830154419 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[2].display_name | Chemistry |
| concepts[3].id | https://openalex.org/C187961010 |
| concepts[3].level | 2 |
| concepts[3].score | 0.5961877107620239 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q260463 |
| concepts[3].display_name | Electron paramagnetic resonance |
| concepts[4].id | https://openalex.org/C139066938 |
| concepts[4].level | 2 |
| concepts[4].score | 0.4795953333377838 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q185056 |
| concepts[4].display_name | Radical |
| concepts[5].id | https://openalex.org/C2778978742 |
| concepts[5].level | 3 |
| concepts[5].score | 0.4621255099773407 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q6717498 |
| concepts[5].display_name | MRI contrast agent |
| concepts[6].id | https://openalex.org/C75473681 |
| concepts[6].level | 1 |
| concepts[6].score | 0.31976181268692017 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q188651 |
| concepts[6].display_name | Photochemistry |
| concepts[7].id | https://openalex.org/C46141821 |
| concepts[7].level | 1 |
| concepts[7].score | 0.30828359723091125 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q209402 |
| concepts[7].display_name | Nuclear magnetic resonance |
| concepts[8].id | https://openalex.org/C557651011 |
| concepts[8].level | 2 |
| concepts[8].score | 0.13957124948501587 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q1832 |
| concepts[8].display_name | Gadolinium |
| concepts[9].id | https://openalex.org/C178790620 |
| concepts[9].level | 1 |
| concepts[9].score | 0.1207427978515625 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q11351 |
| concepts[9].display_name | Organic chemistry |
| concepts[10].id | https://openalex.org/C121332964 |
| concepts[10].level | 0 |
| concepts[10].score | 0.0 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[10].display_name | Physics |
| keywords[0].id | https://openalex.org/keywords/nitroxyl |
| keywords[0].score | 0.8844101428985596 |
| keywords[0].display_name | Nitroxyl |
| keywords[1].id | https://openalex.org/keywords/redox |
| keywords[1].score | 0.7606981992721558 |
| keywords[1].display_name | Redox |
| keywords[2].id | https://openalex.org/keywords/chemistry |
| keywords[2].score | 0.6745520830154419 |
| keywords[2].display_name | Chemistry |
| keywords[3].id | https://openalex.org/keywords/electron-paramagnetic-resonance |
| keywords[3].score | 0.5961877107620239 |
| keywords[3].display_name | Electron paramagnetic resonance |
| keywords[4].id | https://openalex.org/keywords/radical |
| keywords[4].score | 0.4795953333377838 |
| keywords[4].display_name | Radical |
| keywords[5].id | https://openalex.org/keywords/mri-contrast-agent |
| keywords[5].score | 0.4621255099773407 |
| keywords[5].display_name | MRI contrast agent |
| keywords[6].id | https://openalex.org/keywords/photochemistry |
| keywords[6].score | 0.31976181268692017 |
| keywords[6].display_name | Photochemistry |
| keywords[7].id | https://openalex.org/keywords/nuclear-magnetic-resonance |
| keywords[7].score | 0.30828359723091125 |
| keywords[7].display_name | Nuclear magnetic resonance |
| keywords[8].id | https://openalex.org/keywords/gadolinium |
| keywords[8].score | 0.13957124948501587 |
| keywords[8].display_name | Gadolinium |
| keywords[9].id | https://openalex.org/keywords/organic-chemistry |
| keywords[9].score | 0.1207427978515625 |
| keywords[9].display_name | Organic chemistry |
| language | en |
| locations[0].id | doi:10.1089/ars.2021.0110 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S88052261 |
| locations[0].source.issn | 1523-0864, 1557-7716 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 1523-0864 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Antioxidants and Redox Signaling |
| locations[0].source.host_organization | https://openalex.org/P4310320443 |
| locations[0].source.host_organization_name | Mary Ann Liebert, Inc. |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320443 |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Antioxidants & Redox Signaling |
| locations[0].landing_page_url | https://doi.org/10.1089/ars.2021.0110 |
| locations[1].id | pmh:oai:pubmedcentral.nih.gov:8792502 |
| locations[1].is_oa | True |
| locations[1].source.id | https://openalex.org/S2764455111 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed Central |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | other-oa |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | Text |
| locations[1].license_id | https://openalex.org/licenses/other-oa |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Antioxid Redox Signal |
| locations[1].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/8792502 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5061175261 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-8151-4067 |
| authorships[0].author.display_name | Ken‐ichiro Matsumoto |
| authorships[0].countries | JP |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210114217 |
| authorships[0].affiliations[0].raw_affiliation_string | Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[0].institutions[0].id | https://openalex.org/I4210114217 |
| authorships[0].institutions[0].ror | https://ror.org/020rbyg91 |
| authorships[0].institutions[0].type | facility |
| authorships[0].institutions[0].lineage | https://openalex.org/I4210114217 |
| authorships[0].institutions[0].country_code | JP |
| authorships[0].institutions[0].display_name | National Institutes for Quantum Science and Technology |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Ken-Ichiro Matsumoto |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[1].author.id | https://openalex.org/A5035689640 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-9204-0664 |
| authorships[1].author.display_name | Ikuo Nakanishi |
| authorships[1].countries | JP |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210114217 |
| authorships[1].affiliations[0].raw_affiliation_string | Quantum RedOx Chemistry Group, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[1].institutions[0].id | https://openalex.org/I4210114217 |
| authorships[1].institutions[0].ror | https://ror.org/020rbyg91 |
| authorships[1].institutions[0].type | facility |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210114217 |
| authorships[1].institutions[0].country_code | JP |
| authorships[1].institutions[0].display_name | National Institutes for Quantum Science and Technology |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Ikuo Nakanishi |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Quantum RedOx Chemistry Group, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[2].author.id | https://openalex.org/A5078458496 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-0106-2401 |
| authorships[2].author.display_name | Zhivko Zhelev |
| authorships[2].countries | BG |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I24768866, https://openalex.org/I4210103918 |
| authorships[2].affiliations[0].raw_affiliation_string | Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria. |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I173112312 |
| authorships[2].affiliations[1].raw_affiliation_string | Medical Faculty, Trakia University, Stara Zagora, Bulgaria. |
| authorships[2].institutions[0].id | https://openalex.org/I24768866 |
| authorships[2].institutions[0].ror | https://ror.org/01x8hew03 |
| authorships[2].institutions[0].type | government |
| authorships[2].institutions[0].lineage | https://openalex.org/I24768866 |
| authorships[2].institutions[0].country_code | BG |
| authorships[2].institutions[0].display_name | Bulgarian Academy of Sciences |
| authorships[2].institutions[1].id | https://openalex.org/I4210103918 |
| authorships[2].institutions[1].ror | https://ror.org/01dxqkr82 |
| authorships[2].institutions[1].type | facility |
| authorships[2].institutions[1].lineage | https://openalex.org/I24768866, https://openalex.org/I4210103918 |
| authorships[2].institutions[1].country_code | BG |
| authorships[2].institutions[1].display_name | Institute of Biophysics and Biomedical Engineering |
| authorships[2].institutions[2].id | https://openalex.org/I173112312 |
| authorships[2].institutions[2].ror | https://ror.org/04p2cym91 |
| authorships[2].institutions[2].type | education |
| authorships[2].institutions[2].lineage | https://openalex.org/I173112312 |
| authorships[2].institutions[2].country_code | BG |
| authorships[2].institutions[2].display_name | Trakia University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Zhivko Zhelev |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria., Medical Faculty, Trakia University, Stara Zagora, Bulgaria. |
| authorships[3].author.id | https://openalex.org/A5073720264 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-5309-3250 |
| authorships[3].author.display_name | Rumiana Bakalova |
| authorships[3].countries | JP |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210114217 |
| authorships[3].affiliations[0].raw_affiliation_string | Functional and Molecular Imaging Goup, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[3].institutions[0].id | https://openalex.org/I4210114217 |
| authorships[3].institutions[0].ror | https://ror.org/020rbyg91 |
| authorships[3].institutions[0].type | facility |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210114217 |
| authorships[3].institutions[0].country_code | JP |
| authorships[3].institutions[0].display_name | National Institutes for Quantum Science and Technology |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Rumiana Bakalova |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Functional and Molecular Imaging Goup, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[4].author.id | https://openalex.org/A5026082206 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-4429-5053 |
| authorships[4].author.display_name | Ichio Aoki |
| authorships[4].countries | JP |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210114217 |
| authorships[4].affiliations[0].raw_affiliation_string | Functional and Molecular Imaging Goup, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| authorships[4].institutions[0].id | https://openalex.org/I4210114217 |
| authorships[4].institutions[0].ror | https://ror.org/020rbyg91 |
| authorships[4].institutions[0].type | facility |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210114217 |
| authorships[4].institutions[0].country_code | JP |
| authorships[4].institutions[0].display_name | National Institutes for Quantum Science and Technology |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Ichio Aoki |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Functional and Molecular Imaging Goup, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Japan. |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1089/ars.2021.0110 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T12381 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1304 |
| primary_topic.subfield.display_name | Biophysics |
| primary_topic.display_name | Electron Spin Resonance Studies |
| related_works | https://openalex.org/W2257039573, https://openalex.org/W1981011544, https://openalex.org/W2082337540, https://openalex.org/W2084916282, https://openalex.org/W1512411596, https://openalex.org/W1994875143, https://openalex.org/W2031718554, https://openalex.org/W1974704866, https://openalex.org/W4283394167, https://openalex.org/W1969917769 |
| cited_by_count | 28 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 4 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 14 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 7 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 2 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 1 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1089/ars.2021.0110 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S88052261 |
| best_oa_location.source.issn | 1523-0864, 1557-7716 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 1523-0864 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Antioxidants and Redox Signaling |
| best_oa_location.source.host_organization | https://openalex.org/P4310320443 |
| best_oa_location.source.host_organization_name | Mary Ann Liebert, Inc. |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320443 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Antioxidants & Redox Signaling |
| best_oa_location.landing_page_url | https://doi.org/10.1089/ars.2021.0110 |
| primary_location.id | doi:10.1089/ars.2021.0110 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S88052261 |
| primary_location.source.issn | 1523-0864, 1557-7716 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 1523-0864 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Antioxidants and Redox Signaling |
| primary_location.source.host_organization | https://openalex.org/P4310320443 |
| primary_location.source.host_organization_name | Mary Ann Liebert, Inc. |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320443 |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Antioxidants & Redox Signaling |
| primary_location.landing_page_url | https://doi.org/10.1089/ars.2021.0110 |
| publication_date | 2021-06-19 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2041599257, https://openalex.org/W2036642902, https://openalex.org/W2079629366, https://openalex.org/W2175724880, https://openalex.org/W2164947780, https://openalex.org/W2734471890, https://openalex.org/W2315152480, https://openalex.org/W2118489870, https://openalex.org/W2276951999, https://openalex.org/W1987925604, https://openalex.org/W2039504221, https://openalex.org/W2120687053, https://openalex.org/W2089918257, https://openalex.org/W2025621591, https://openalex.org/W2091588673, https://openalex.org/W1974808250, https://openalex.org/W2013735638, https://openalex.org/W2580568552, https://openalex.org/W2143865882, https://openalex.org/W2007652379, https://openalex.org/W2012538401, https://openalex.org/W2091695541, https://openalex.org/W2048445679, https://openalex.org/W2159620550, https://openalex.org/W2047320077, https://openalex.org/W2003615705, https://openalex.org/W2168961368, https://openalex.org/W2009941651, https://openalex.org/W1983361372, https://openalex.org/W2010154445, https://openalex.org/W2170048907, https://openalex.org/W2129139391, https://openalex.org/W2162583612, https://openalex.org/W2063968962, https://openalex.org/W2254833392, https://openalex.org/W1936016984, https://openalex.org/W2888809401, https://openalex.org/W2297999778, https://openalex.org/W2564764757, https://openalex.org/W2138343392, https://openalex.org/W1995391156, https://openalex.org/W1982981389, https://openalex.org/W2002696858, https://openalex.org/W2030822242, https://openalex.org/W1987711183, https://openalex.org/W2103253419, https://openalex.org/W1997188535, https://openalex.org/W2574729245, https://openalex.org/W2768587619, https://openalex.org/W1969884510, https://openalex.org/W2009715921, https://openalex.org/W2056423472, https://openalex.org/W2073844815, https://openalex.org/W2033629783, https://openalex.org/W2955986175, https://openalex.org/W2088670270, https://openalex.org/W2002267791, https://openalex.org/W2786099644, https://openalex.org/W2587833196, https://openalex.org/W2046331938, https://openalex.org/W1979065260, https://openalex.org/W2089050953, https://openalex.org/W2067125077, https://openalex.org/W2022307275, https://openalex.org/W2061716265, https://openalex.org/W1990956904, https://openalex.org/W2027707520, https://openalex.org/W2049556823, https://openalex.org/W2091164879, https://openalex.org/W2016638950, https://openalex.org/W2087815322, https://openalex.org/W2007637907, https://openalex.org/W1975052150, https://openalex.org/W2004702412, https://openalex.org/W2160810259, https://openalex.org/W1969939392, https://openalex.org/W2001982092, https://openalex.org/W2124067042, https://openalex.org/W2116808031, https://openalex.org/W2078950699, https://openalex.org/W2153499363, https://openalex.org/W3012686691, https://openalex.org/W2134723636, https://openalex.org/W2085166331, https://openalex.org/W2011082615, https://openalex.org/W2127067439, https://openalex.org/W1984044427, https://openalex.org/W4238786546, https://openalex.org/W4241880657, https://openalex.org/W2071552103, https://openalex.org/W2036215130, https://openalex.org/W2076267530, https://openalex.org/W2061487178, https://openalex.org/W2011482669, https://openalex.org/W2557097191, https://openalex.org/W3024091934, https://openalex.org/W4231676299, https://openalex.org/W2997821977, https://openalex.org/W4229886959, https://openalex.org/W2322116467, https://openalex.org/W3023402336, https://openalex.org/W2050550723, https://openalex.org/W1965422288, https://openalex.org/W2018301088, https://openalex.org/W2524916887, https://openalex.org/W1993910598, https://openalex.org/W2013152174, https://openalex.org/W2168262437, https://openalex.org/W2041596729, https://openalex.org/W2416033676, https://openalex.org/W2153912174, https://openalex.org/W2060006939, https://openalex.org/W2045109820, https://openalex.org/W2932666635, https://openalex.org/W1989690974, https://openalex.org/W2160700625, https://openalex.org/W2121243426, https://openalex.org/W2098056848, https://openalex.org/W2115711333, https://openalex.org/W2056009036, https://openalex.org/W2110302810, https://openalex.org/W2084141237, https://openalex.org/W2070489370, https://openalex.org/W1850607917, https://openalex.org/W2040446206, https://openalex.org/W2011615798, https://openalex.org/W2969635730, https://openalex.org/W2046320591, https://openalex.org/W3081445517, https://openalex.org/W2898877847, https://openalex.org/W2077072716, https://openalex.org/W1990804638, https://openalex.org/W2802091420, https://openalex.org/W2170853848, https://openalex.org/W2081168544, https://openalex.org/W1574903426, https://openalex.org/W1982668495, https://openalex.org/W1916294284, https://openalex.org/W2566333039, https://openalex.org/W2561689434, https://openalex.org/W2027900991, https://openalex.org/W2232874151, https://openalex.org/W1967249348, https://openalex.org/W2091907357, https://openalex.org/W1963782014, https://openalex.org/W2029517070, https://openalex.org/W2066656717, https://openalex.org/W2113472065, https://openalex.org/W2053146261, https://openalex.org/W2090848337, https://openalex.org/W2055876681, https://openalex.org/W2034914370, https://openalex.org/W2046396329, https://openalex.org/W2081655836, https://openalex.org/W2625947545, https://openalex.org/W2028111455, https://openalex.org/W2052794865, https://openalex.org/W2154272635, https://openalex.org/W2162214261, https://openalex.org/W2047913421, https://openalex.org/W2002919624, https://openalex.org/W2160527898, https://openalex.org/W2325034715, https://openalex.org/W2062845561, https://openalex.org/W2052830369, https://openalex.org/W2076236935, https://openalex.org/W2073170100, https://openalex.org/W2078904364, https://openalex.org/W1558170796, https://openalex.org/W2081176061, https://openalex.org/W2142355345, https://openalex.org/W2792448780, https://openalex.org/W2112741711, https://openalex.org/W1968258862, https://openalex.org/W2330388042, https://openalex.org/W2796612969, https://openalex.org/W2032314354, https://openalex.org/W2089603494, https://openalex.org/W17359041, https://openalex.org/W1994526772, https://openalex.org/W1999640696, https://openalex.org/W2182589748, https://openalex.org/W2781581839, https://openalex.org/W2059550566, https://openalex.org/W2018035269, https://openalex.org/W1978488634, https://openalex.org/W2057541479, https://openalex.org/W2162285123, https://openalex.org/W2940195999, https://openalex.org/W2111993560, https://openalex.org/W1739148075, https://openalex.org/W1670931368, https://openalex.org/W1913419146, https://openalex.org/W2784921274, https://openalex.org/W2051002194, https://openalex.org/W2020901172, https://openalex.org/W130674812, https://openalex.org/W1762358069, https://openalex.org/W608968912, https://openalex.org/W1569934359, https://openalex.org/W2148967348, https://openalex.org/W1515850699, https://openalex.org/W1576963653 |
| referenced_works_count | 203 |
| abstract_inverted_index.A | 158 |
| abstract_inverted_index.a | 36, 144, 191 |
| abstract_inverted_index.In | 1, 51 |
| abstract_inverted_index.an | 19, 196 |
| abstract_inverted_index.as | 35, 42, 58, 107, 183, 202 |
| abstract_inverted_index.be | 18, 190 |
| abstract_inverted_index.by | 129 |
| abstract_inverted_index.in | 85, 121 |
| abstract_inverted_index.is | 40, 132, 178 |
| abstract_inverted_index.of | 4, 9, 21, 28, 78, 89, 160 |
| abstract_inverted_index.on | 13, 45, 75 |
| abstract_inverted_index.to | 65, 134, 194 |
| abstract_inverted_index.36, | 209 |
| abstract_inverted_index.EPR | 130 |
| abstract_inverted_index.The | 25 |
| abstract_inverted_index.and | 6, 71, 154, 173 |
| abstract_inverted_index.can | 17, 189 |
| abstract_inverted_index.for | 100, 165 |
| abstract_inverted_index.has | 62 |
| abstract_inverted_index.is, | 148 |
| abstract_inverted_index.low | 174 |
| abstract_inverted_index.use | 34 |
| abstract_inverted_index.MRI. | 138 |
| abstract_inverted_index.been | 63, 83, 152 |
| abstract_inverted_index.from | 137 |
| abstract_inverted_index.have | 82, 114, 151 |
| abstract_inverted_index.high | 170 |
| abstract_inverted_index.seen | 41 |
| abstract_inverted_index.such | 201 |
| abstract_inverted_index.that | 147 |
| abstract_inverted_index.tool | 193 |
| abstract_inverted_index.used | 120 |
| abstract_inverted_index.vivo | 2, 52 |
| abstract_inverted_index.were | 98 |
| abstract_inverted_index.with | 118, 169 |
| abstract_inverted_index.(EPR) | 125 |
| abstract_inverted_index.(MRI) | 111 |
| abstract_inverted_index.Redox | 207 |
| abstract_inverted_index.agent | 164 |
| abstract_inverted_index.based | 12 |
| abstract_inverted_index.being | 43 |
| abstract_inverted_index.drug, | 150 |
| abstract_inverted_index.drugs | 97 |
| abstract_inverted_index.index | 20 |
| abstract_inverted_index.redox | 15, 23, 26, 53, 68, 199 |
| abstract_inverted_index.their | 33 |
| abstract_inverted_index.those | 119 |
| abstract_inverted_index.types | 88 |
| abstract_inverted_index.under | 179 |
| abstract_inverted_index.using | 55 |
| abstract_inverted_index.which | 31 |
| abstract_inverted_index.while | 127 |
| abstract_inverted_index.Future | 156 |
| abstract_inverted_index.Recent | 49 |
| abstract_inverted_index.agents | 61, 93, 113, 142, 188 |
| abstract_inverted_index.and/or | 94 |
| abstract_inverted_index.assess | 66 |
| abstract_inverted_index.cyclic | 14 |
| abstract_inverted_index.detect | 195 |
| abstract_inverted_index.having | 143 |
| abstract_inverted_index.normal | 37, 175 |
| abstract_inverted_index.status | 200 |
| abstract_inverted_index.tissue | 22, 67, 176, 198 |
| abstract_inverted_index.useful | 192 |
| abstract_inverted_index.Issues: | 104 |
| abstract_inverted_index.Polymer | 87 |
| abstract_inverted_index.Signal. | 208 |
| abstract_inverted_index.detail. | 86 |
| abstract_inverted_index.enables | 32 |
| abstract_inverted_index.imaging | 54, 110 |
| abstract_inverted_index.radical | 80, 91 |
| abstract_inverted_index.several | 115 |
| abstract_inverted_index.status. | 24, 69 |
| abstract_inverted_index.stress. | 205 |
| abstract_inverted_index.support | 128 |
| abstract_inverted_index.Chemical | 70 |
| abstract_inverted_index.Critical | 103 |
| abstract_inverted_index.Nitroxyl | 105, 181 |
| abstract_inverted_index.abnormal | 197 |
| abstract_inverted_index.benefit, | 146 |
| abstract_inverted_index.chemical | 76 |
| abstract_inverted_index.compared | 117 |
| abstract_inverted_index.contrast | 60, 92, 112, 141, 163, 187 |
| abstract_inverted_index.designed | 99 |
| abstract_inverted_index.electron | 122 |
| abstract_inverted_index.imaging, | 126 |
| abstract_inverted_index.magnetic | 108, 185 |
| abstract_inverted_index.nitroxyl | 10, 29, 56, 79, 90, 95, 162 |
| abstract_inverted_index.planning | 46 |
| abstract_inverted_index.radicals | 11, 57, 106, 182 |
| abstract_inverted_index.reaction | 171 |
| abstract_inverted_index.suitable | 161 |
| abstract_inverted_index.therapy. | 48 |
| abstract_inverted_index.toxicity | 177 |
| abstract_inverted_index.95–121. | 210 |
| abstract_inverted_index.Advances: | 50 |
| abstract_inverted_index.Antioxid. | 206 |
| abstract_inverted_index.behaviors | 73 |
| abstract_inverted_index.compounds | 81 |
| abstract_inverted_index.depending | 74 |
| abstract_inverted_index.developed | 64, 153 |
| abstract_inverted_index.important | 133 |
| abstract_inverted_index.mechanism | 16, 27 |
| abstract_inverted_index.medicinal | 145 |
| abstract_inverted_index.oxidative | 204 |
| abstract_inverted_index.progress. | 180 |
| abstract_inverted_index.proposed. | 155 |
| abstract_inverted_index.radiation | 47 |
| abstract_inverted_index.radicals, | 30 |
| abstract_inverted_index.resonance | 109, 124, 186 |
| abstract_inverted_index.advantages | 116 |
| abstract_inverted_index.assessment | 3 |
| abstract_inverted_index.attractive | 44 |
| abstract_inverted_index.biological | 72 |
| abstract_inverted_index.disordered | 203 |
| abstract_inverted_index.structures | 77 |
| abstract_inverted_index.understand | 135 |
| abstract_inverted_index.understood | 84 |
| abstract_inverted_index.Directions: | 157 |
| abstract_inverted_index.approaching | 101 |
| abstract_inverted_index.conversions | 8 |
| abstract_inverted_index.development | 159 |
| abstract_inverted_index.diamagnetic | 7 |
| abstract_inverted_index.information | 136 |
| abstract_inverted_index.specificity | 172 |
| abstract_inverted_index.theranostic | 167 |
| abstract_inverted_index.applications | 168 |
| abstract_inverted_index.paramagnetic | 5, 123, 140 |
| abstract_inverted_index.spectroscopy | 131 |
| abstract_inverted_index.Significance: | 0 |
| abstract_inverted_index.theranostics. | 102 |
| abstract_inverted_index.translational | 166 |
| abstract_inverted_index.Redox-sensitive | 139 |
| abstract_inverted_index.radical-labeled | 96 |
| abstract_inverted_index.radioprotector, | 39 |
| abstract_inverted_index.redox-sensitive | 59, 184 |
| abstract_inverted_index.nitroxyl-labeled | 149 |
| abstract_inverted_index.tissue-selective | 38 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5061175261 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 5 |
| corresponding_institution_ids | https://openalex.org/I4210114217 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.46000000834465027 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.96093096 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |