Nonbifurcating Phylogenetic Tree Inference via the Adaptive LASSO Article Swipe
YOU?
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· 2020
· Open Access
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· DOI: https://doi.org/10.1080/01621459.2020.1778481
Phylogenetic tree inference using deep DNA sequencing is reshaping our understanding of rapidly evolving systems, such as the within-host battle between viruses and the immune system. Densely sampled phylogenetic trees can contain special features, including sampled ancestors in which we sequence a genotype along with its direct descendants, and polytomies in which multiple descendants arise simultaneously. These features are apparent after identifying zero-length branches in the tree. However, current maximum-likelihood based approaches are not capable of revealing such zero-length branches. In this paper, we find these zero-length branches by introducing adaptive-LASSO-type regularization estimators for the branch lengths of phylogenetic trees, deriving their properties, and showing regularization to be a practically useful approach for phylogenetics.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1080/01621459.2020.1778481
- OA Status
- green
- Cited By
- 3
- References
- 81
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3035455049
Raw OpenAlex JSON
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https://openalex.org/W3035455049Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/01621459.2020.1778481Digital Object Identifier
- Title
-
Nonbifurcating Phylogenetic Tree Inference via the Adaptive LASSOWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-06-09Full publication date if available
- Authors
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Cheng Zhang, Vu Dinh, F. A. MatsenList of authors in order
- Landing page
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https://doi.org/10.1080/01621459.2020.1778481Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://www.ncbi.nlm.nih.gov/pmc/articles/8300927Direct OA link when available
- Concepts
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Phylogenetic tree, Computational phylogenetics, Lasso (programming language), Phylogenetic network, Inference, Tree (set theory), Phylogenetics, Biology, Evolutionary biology, Tree rearrangement, Regularization (linguistics), Mathematics, Artificial intelligence, Computer science, Genetics, Combinatorics, Gene, World Wide WebTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2022: 1, 2020: 1Per-year citation counts (last 5 years)
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81Number of works referenced by this work
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-
10Other works algorithmically related by OpenAlex
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