NORMAL VALUES OF ESOPHAGEAL HIGH-RESOLUTION MANOMETRY: A BRAZILIAN MULTICENTER STUDY Article Swipe
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· 2020
· Open Access
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· DOI: https://doi.org/10.1590/s0004-2803.202000000-40
BACKGROUND: The high-resolution manometry has been a significant advance in esophageal diagnostics. There are different types of catheter and systems devices to capture esophageal pressures that generate variable data related to Chicago Classification (CC) and consequently influence normal values results. There are not normative data for the 24-channel water-perfused high-resolution manometry system most used in Brazil with healthy volunteers in supine posture. OBJECTIVE: To determine manometric esophageal normative values for a 24-channel water-perfused high-resolution manometry catheter in supine posture using healthy volunteers according to CC 3.0 parameters. METHODS: A total of 92 volunteers with no gastrointestinal symptoms or medications affecting GI motility underwent esophageal high-resolution manometry by standard protocol. Age, gender and manometry parameters analyzed using Alacer software were collected. The median, range, and 5th and 95th percentiles (where applicable) were obtained for all high-resolution manometry metrics. Normal value percentiles were defined as 95th integrated relaxation pressure, 5th-100th distal contractile integral, and 5th distal latency. RESULTS: The mean age was 40.5±13.2 years. Our normative metrics were integrated relaxation pressure 4 cm). For EGJ-CI the range 5th-95th was 21.7-86.9 mmHg.cm.s. CONCLUSION: This is the first report of normative data for the 24-channel water-perfused system in supine posture. It revealed higher integrated relaxation pressure and distal latency duration which suggest the need to change CC 3.0 cutoffs for this system. It is observed that there is a tendency that DCI >7000 mmHg.cm.s may represent the lower limit of hypercontractility, and when <700 mmHg.cm.s (<5% percentile) interpreted as ineffective esophageal motility or failcontraction. Also compared to Chicago 3.0, higher integrated relaxation pressure and duration of distal latency were found. We emphasize that these data must be confirmed by future studies.
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- article
- Language
- en
- Landing Page
- https://doi.org/10.1590/s0004-2803.202000000-40
- http://www.scielo.br/j/ag/a/cQLzsw6tJFxWrbFftWt5VWS/?format=pdf&lang=en
- OA Status
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- Cited By
- 6
- References
- 24
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- OpenAlex ID
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- OpenAlex ID
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https://openalex.org/W3025001953Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1590/s0004-2803.202000000-40Digital Object Identifier
- Title
-
NORMAL VALUES OF ESOPHAGEAL HIGH-RESOLUTION MANOMETRY: A BRAZILIAN MULTICENTER STUDYWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-05-11Full publication date if available
- Authors
-
Gerson Domingues, Nelson Henrique Michelsohn, Ricardo Guilherme Viebig, Décio Chinzon, Ary Nasi, Carla Thamires Laranjeira Granja, Eponina Lemme, Luiz Abrahão, Mauricio Gustavo Bravim, Miguel Angelo N. Souza, Nayara Salgado Carvalho, Paulo J.P.C. Carvalho, Tomás Navarro-Rodríguez, Joaquim P. Moraes-FilhoList of authors in order
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https://doi.org/10.1590/s0004-2803.202000000-40Publisher landing page
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https://www.scielo.br/j/ag/a/cQLzsw6tJFxWrbFftWt5VWS/?format=pdf&lang=enDirect link to full text PDF
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YesWhether a free full text is available
- OA status
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diamondOpen access status per OpenAlex
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https://www.scielo.br/j/ag/a/cQLzsw6tJFxWrbFftWt5VWS/?format=pdf&lang=enDirect OA link when available
- Concepts
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Medicine, Supine position, High resolution manometry, Percentile, Peristalsis, Nuclear medicine, Esophageal motility disorder, Internal medicine, Cardiology, Radiology, Esophagus, Achalasia, Mathematics, StatisticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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6Total citation count in OpenAlex
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2024: 3, 2022: 1, 2021: 1, 2020: 1Per-year citation counts (last 5 years)
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24Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.systems | 20 |
| abstract_inverted_index.>7000 | 246 |
| abstract_inverted_index.5th-95th | 193 |
| abstract_inverted_index.ABSTRACT | 0 |
| abstract_inverted_index.METHODS: | 88 |
| abstract_inverted_index.RESULTS: | 156 |
| abstract_inverted_index.analyzed | 115 |
| abstract_inverted_index.catheter | 18, 76 |
| abstract_inverted_index.compared | 269 |
| abstract_inverted_index.duration | 223, 278 |
| abstract_inverted_index.generate | 27 |
| abstract_inverted_index.integral | 175 |
| abstract_inverted_index.latency. | 155 |
| abstract_inverted_index.metrics. | 137 |
| abstract_inverted_index.motility | 102, 265 |
| abstract_inverted_index.observed | 238 |
| abstract_inverted_index.obtained | 132 |
| abstract_inverted_index.posture. | 62, 213 |
| abstract_inverted_index.pressure | 169, 219, 276 |
| abstract_inverted_index.results. | 40 |
| abstract_inverted_index.revealed | 215 |
| abstract_inverted_index.software | 118 |
| abstract_inverted_index.standard | 108 |
| abstract_inverted_index.studies. | 294 |
| abstract_inverted_index.symptoms | 97 |
| abstract_inverted_index.tendency | 243 |
| abstract_inverted_index.variable | 28 |
| abstract_inverted_index.(708-4111 | 176 |
| abstract_inverted_index.21.7-86.9 | 195 |
| abstract_inverted_index.5th-100th | 148 |
| abstract_inverted_index.according | 83 |
| abstract_inverted_index.affecting | 100 |
| abstract_inverted_index.confirmed | 291 |
| abstract_inverted_index.determine | 65 |
| abstract_inverted_index.different | 15 |
| abstract_inverted_index.emphasize | 285 |
| abstract_inverted_index.influence | 37 |
| abstract_inverted_index.integral, | 151 |
| abstract_inverted_index.manometry | 4, 51, 75, 106, 113, 136 |
| abstract_inverted_index.mmHg.cm.s | 247, 258 |
| abstract_inverted_index.normative | 44, 68, 164, 204 |
| abstract_inverted_index.pressure, | 147 |
| abstract_inverted_index.pressures | 25 |
| abstract_inverted_index.protocol. | 109 |
| abstract_inverted_index.represent | 249 |
| abstract_inverted_index.underwent | 103 |
| abstract_inverted_index.24-channel | 48, 72, 208 |
| abstract_inverted_index.40.5±13.2 | 161 |
| abstract_inverted_index.OBJECTIVE: | 63 |
| abstract_inverted_index.collected. | 120 |
| abstract_inverted_index.esophageal | 11, 24, 67, 104, 264 |
| abstract_inverted_index.integrated | 145, 167, 217, 274 |
| abstract_inverted_index.manometric | 66 |
| abstract_inverted_index.mmHg.cm.s) | 177 |
| abstract_inverted_index.mmHg.cm.s. | 196 |
| abstract_inverted_index.parameters | 114 |
| abstract_inverted_index.relaxation | 146, 168, 218, 275 |
| abstract_inverted_index.volunteers | 59, 82, 93 |
| abstract_inverted_index.BACKGROUND: | 1 |
| abstract_inverted_index.CONCLUSION: | 197 |
| abstract_inverted_index.applicable) | 130 |
| abstract_inverted_index.contractile | 150, 174 |
| abstract_inverted_index.ineffective | 263 |
| abstract_inverted_index.interpreted | 261 |
| abstract_inverted_index.medications | 99 |
| abstract_inverted_index.parameters. | 87 |
| abstract_inverted_index.percentile) | 260 |
| abstract_inverted_index.percentiles | 128, 140 |
| abstract_inverted_index.peristaltic | 184 |
| abstract_inverted_index.significant | 8 |
| abstract_inverted_index.consequently | 36 |
| abstract_inverted_index.diagnostics. | 12 |
| abstract_inverted_index.Classification | 33 |
| abstract_inverted_index.water-perfused | 49, 73, 209 |
| abstract_inverted_index.high-resolution | 3, 50, 74, 105, 135 |
| abstract_inverted_index.failcontraction. | 267 |
| abstract_inverted_index.gastrointestinal | 96 |
| abstract_inverted_index.hypercontractility, | 254 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 14 |
| citation_normalized_percentile.value | 0.63770266 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |