Novel and Alternative Surgical Techniques for Cartilage Disorders of the Knee. Article Swipe
Articular cartilage lesions of the knee, ranging from focal defects to tricompartmental osteoarthritis, present significant clinical challenges because of cartilage's limited regenerative capacity. It is important to highlight modern surgical advancements in the treatment of chondral pathology beyond injection therapy, traditional osteotomies, and arthroplasty options. Surface- and cell-based repair techniques, including matrix-induced autologous chondrocyte implantation, offer improved long-term outcomes, with emerging fourth-generation variants facilitating single-stage arthroscopic implantation. Off-the-shelf cartilage repair strategies, such as particulated juvenile cartilage, micronized allografts, and viable cartilage allografts, represent promising alternatives that bypass the need for two-stage procedures. For osteochondral defects, osteochondral autograft transfer and fresh allograft transplantation remain the gold standard, although decellularized and cryopreserved viable allografts are under investigation. Recently approved artificial osteochondral scaffolds, such as Agili-C, offer an FDA-cleared, acellular biphasic implant with promising midterm results. For patients with malalignment-associated osteoarthritis, patient-specific instrumentation in high tibial and distal femoral osteotomies enhances accuracy, particularly in biplanar corrections, and reduces intraoperative variability. Novel load-sharing implants, such as fiber-reinforced rafting nails and the MISHA knee system, provide less invasive alternatives to osteotomy, showing early success in reducing medial compartment load and improving functional outcomes. There is an expanding arsenal of biologically and biomechanically innovative treatments for articular cartilage restoration and osteoarthritis management.
Related Topics
Concepts
Medicine
Cartilage
Surgery
Osteoarthritis
Articular cartilage
Decellularization
Transplantation
Articular cartilage damage
Osteochondritis dissecans
Autologous chondrocyte implantation
Chondrocyte
Articular cartilage repair
Arthroplasty
Implant
Chondropathy
Cartilage damage
Vascularity
Arthroscopy
Tissue engineering
Reduction (mathematics)
Bone marrow aspirate
Orthopedic surgery
Regenerative medicine
Articular surface
Minimally invasive procedures
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://pubmed.ncbi.nlm.nih.gov/41289447
- OA Status
- closed
- OpenAlex ID
- https://openalex.org/W7106782075
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W7106782075Canonical identifier for this work in OpenAlex
- Title
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Novel and Alternative Surgical Techniques for Cartilage Disorders of the Knee.Work title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2026Year of publication
- Publication date
-
2026-01-01Full publication date if available
- Authors
-
Andrew S Bi, Larry Chen, James Lee Pace, Alexander Golant, Laith M. JazrawiList of authors in order
- Landing page
-
https://pubmed.ncbi.nlm.nih.gov/41289447Publisher landing page
- Open access
-
NoWhether a free full text is available
- OA status
-
closedOpen access status per OpenAlex
- Concepts
-
Medicine, Cartilage, Surgery, Osteoarthritis, Articular cartilage, Decellularization, Transplantation, Articular cartilage damage, Osteochondritis dissecans, Autologous chondrocyte implantation, Chondrocyte, Articular cartilage repair, Arthroplasty, Implant, Chondropathy, Cartilage damage, Vascularity, Arthroscopy, Tissue engineering, Reduction (mathematics), Bone marrow aspirate, Orthopedic surgery, Regenerative medicine, Articular surface, Minimally invasive proceduresTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
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| abstract_inverted_index.osteotomies | 146 |
| abstract_inverted_index.procedures. | 91 |
| abstract_inverted_index.restoration | 202 |
| abstract_inverted_index.significant | 14 |
| abstract_inverted_index.strategies, | 70 |
| abstract_inverted_index.techniques, | 49 |
| abstract_inverted_index.traditional | 40 |
| abstract_inverted_index.FDA-cleared, | 125 |
| abstract_inverted_index.advancements | 30 |
| abstract_inverted_index.alternatives | 84, 173 |
| abstract_inverted_index.arthroplasty | 43 |
| abstract_inverted_index.arthroscopic | 65 |
| abstract_inverted_index.biologically | 194 |
| abstract_inverted_index.corrections, | 152 |
| abstract_inverted_index.facilitating | 63 |
| abstract_inverted_index.load-sharing | 158 |
| abstract_inverted_index.osteotomies, | 41 |
| abstract_inverted_index.particularly | 149 |
| abstract_inverted_index.particulated | 73 |
| abstract_inverted_index.regenerative | 21 |
| abstract_inverted_index.single-stage | 64 |
| abstract_inverted_index.variability. | 156 |
| abstract_inverted_index.Off-the-shelf | 67 |
| abstract_inverted_index.cryopreserved | 109 |
| abstract_inverted_index.implantation, | 54 |
| abstract_inverted_index.implantation. | 66 |
| abstract_inverted_index.osteochondral | 93, 95, 118 |
| abstract_inverted_index.decellularized | 107 |
| abstract_inverted_index.intraoperative | 155 |
| abstract_inverted_index.investigation. | 114 |
| abstract_inverted_index.matrix-induced | 51 |
| abstract_inverted_index.osteoarthritis | 204 |
| abstract_inverted_index.biomechanically | 196 |
| abstract_inverted_index.instrumentation | 139 |
| abstract_inverted_index.osteoarthritis, | 12, 137 |
| abstract_inverted_index.transplantation | 101 |
| abstract_inverted_index.fiber-reinforced | 162 |
| abstract_inverted_index.patient-specific | 138 |
| abstract_inverted_index.tricompartmental | 11 |
| abstract_inverted_index.fourth-generation | 61 |
| abstract_inverted_index.malalignment-associated | 136 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 5 |
| citation_normalized_percentile |