Nutritional properties and plausible benefits of Pearl millet (Pennisetum glaucum) on bone metabolism and osteoimmunology : a mini-review Article Swipe
Abdelhafid Nani
,
Meriem Belarbi
,
Naim Akhtar Khan
,
Aziz Hichami
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.51745/najfnr.4.8.336-342
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.51745/najfnr.4.8.336-342
Bone is a hard connective tissue that undergoes a systematic renewal. This highly dynamic organ is made up of four different types of cells, however, bone formation is commonly attributed to osteoblasts and bone resorption to osteoclasts. Bone tissue formation occurs during embryonic development and in certain post-birth pathological conditions. The immune system could influence the functions of bone cells, and the crosstalk between hematopoietic, immune, and bone cells is known as osteoimmunology. Indeed, cytokines produced by immune cells, including TNF-α and IL-6, are critically implicated in bone pathogenesis. It is well established that diet plays an important role in bone health and function. Indeed, antioxidant nutraceuticals-rich diet, of which pearl millet is one, can be effective in treating osteoporosis. Pearl millet (PM) is an African native cereal that constitutes the staple food for African Sahel region inhabitants as well as for many peoples in rural regions in India. Pearl millet grains content in amino acids, minerals, and phytochemicals may contribute to promoting bone health and metabolism. Accordingly, in the current review, we discuss the putative effects of PM nutrients, with a focus on polyphenols, on bone metabolism and osteoimmunology. In the light of our previous studies and others from literature, we speculate that PM whole grains may be effective in the prevention and management of bone pathogenesis. Keywords: PM whole grains, polyphenols, osteoblasts, osteoclasts, osteoimmunology, TNF-α.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.51745/najfnr.4.8.336-342
- OA Status
- diamond
- Cited By
- 1
- References
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W3143357656Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.51745/najfnr.4.8.336-342Digital Object Identifier
- Title
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Nutritional properties and plausible benefits of Pearl millet (Pennisetum glaucum) on bone metabolism and osteoimmunology : a mini-reviewWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-12-27Full publication date if available
- Authors
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Abdelhafid Nani, Meriem Belarbi, Naim Akhtar Khan, Aziz HichamiList of authors in order
- Landing page
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https://doi.org/10.51745/najfnr.4.8.336-342Publisher landing page
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.51745/najfnr.4.8.336-342Direct OA link when available
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Osteoimmunology, Bone remodeling, Immune system, Osteoporosis, Bone cell, Bone resorption, Immunology, Medicine, Biology, Cell biology, Internal medicine, RANKL, Receptor, Activator (genetics)Top concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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70Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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