Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome Article Swipe
Alexandra von Münchow
,
Sarah Torp Yttergren
,
Rasmus Riemer Jakobsen
,
Nanna Lúthersson
,
Axel Kornerup Hansen
,
Frederikke Lindenberg
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3389/frmbi.2023.1194705
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3389/frmbi.2023.1194705
Background The prevalence of Equine Metabolic Syndrome and insulin dysregulation is increasing in the horse population. Insulin dysregulation is a risk factor for laminitis, which has significant welfare consequences for the horse. Current treatment strategies for Equine Metabolic Syndrome have variable effects on insulin sensitivity. Findings suggest that gut microbiota plays an important role in gastrointestinal barrier protection and metabolic diseases. Dietary supplementation with oligosaccharides has been shown to increase the production of short-chain fatty acids and induce changes in the gut microbiota, with an increase in insulin sensitivity. Objectives We hypothesized that dietary oligosaccharide supplementation would ameliorate insulin dysregulation in horses with Equine Metabolic Syndrome. Study design Fifteen horses were included in a cross-over study including two feed supplementations periods with oligosaccharide supplementation or calcium carbonate. Before and after each period plasma insulin, endotoxin, serum amyloid A, and blood glucose concentrations were measured during an oral sugar test and fecal samples were collected. Results Oligosaccharide supplementation significantly reduced insulin in geldings ( p = 0.02). Overall, none of the dominating bacterias changed significantly in relative Δ-abundance. In the gut microbiota of mares, the Akkermansia genus and Clostridiaceae family were significantly more abundant. Within-sample bacterial diversity of horses with insulin concentrations > 60 mIU/L was significantly greater when compared to horses < 60 mIU/L. Horses with insulin concentrations > 60 mIU/L and horses with previous laminitis had a significantly greater beta diversity. Main limitations Cut-off values for oligosaccharide feed supplementation/placebo dosing instead of dosing by g/kg body weight; owner compliance; single blood sample in oral sugar test; inter-horse variation Conclusions This study demonstrated that oligosaccharide supplementation could improve insulin dysregulation in geldings with Equine Metabolic Syndrome suggesting that sex susceptibility might be a factor to consider. Additionally, a tendency of reduction of obesity-associated bacteria was observed. Furthermore, the diversity of the gut microbiota was significantly dependent on laminitis status and insulin concentrations. However, more studies on the effects of oligosaccharide supplementation on insulin dysregulation are needed to improve the dietary management of horses with Equine Metabolic Syndrome.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/frmbi.2023.1194705
- https://www.frontiersin.org/articles/10.3389/frmbi.2023.1194705/pdf
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- OpenAlex ID
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Raw OpenAlex JSON
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- DOI
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https://doi.org/10.3389/frmbi.2023.1194705Digital Object Identifier
- Title
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Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic SyndromeWork title
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-08-02Full publication date if available
- Authors
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Alexandra von Münchow, Sarah Torp Yttergren, Rasmus Riemer Jakobsen, Nanna Lúthersson, Axel Kornerup Hansen, Frederikke LindenbergList of authors in order
- Landing page
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https://doi.org/10.3389/frmbi.2023.1194705Publisher landing page
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https://www.frontiersin.org/articles/10.3389/frmbi.2023.1194705/pdfDirect link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://www.frontiersin.org/articles/10.3389/frmbi.2023.1194705/pdfDirect OA link when available
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Oligosaccharide, Plasma glucose, Insulin, Internal medicine, Endocrinology, Metabolic syndrome, Chemistry, Medicine, Biochemistry, Diabetes mellitusTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| referenced_works | https://openalex.org/W2797966972, https://openalex.org/W2099456560, https://openalex.org/W965274465, https://openalex.org/W4360895040, https://openalex.org/W2263473433, https://openalex.org/W1562241250, https://openalex.org/W2889821831, https://openalex.org/W4290861385, https://openalex.org/W2729203579, https://openalex.org/W2280501212, https://openalex.org/W2233257601, https://openalex.org/W2150679087, https://openalex.org/W1591547519, https://openalex.org/W2131536322, https://openalex.org/W2758183934, https://openalex.org/W2133010654, https://openalex.org/W2020291070, https://openalex.org/W2059951157, https://openalex.org/W2201313988, https://openalex.org/W2021251015, https://openalex.org/W1984020582, https://openalex.org/W2136417551, https://openalex.org/W2188994168, https://openalex.org/W3084798687, https://openalex.org/W2163250554, https://openalex.org/W2914703817, https://openalex.org/W2105102980, https://openalex.org/W2144590482, https://openalex.org/W2147790901, https://openalex.org/W3198223019, https://openalex.org/W1976256751, https://openalex.org/W1550074454, https://openalex.org/W2619690725, https://openalex.org/W2012037560, https://openalex.org/W2131336057, https://openalex.org/W2404939443, https://openalex.org/W1937295898, https://openalex.org/W2324229028, https://openalex.org/W1970283537, https://openalex.org/W3112193393, https://openalex.org/W2162366469, https://openalex.org/W2964169059, https://openalex.org/W3108242426, https://openalex.org/W2139474062, https://openalex.org/W2146117860, https://openalex.org/W2910043955, https://openalex.org/W2971527784, https://openalex.org/W3162190739, https://openalex.org/W2179438025, https://openalex.org/W2116224125, https://openalex.org/W2129690444, https://openalex.org/W2074440162, https://openalex.org/W2037388574, https://openalex.org/W2130807841, https://openalex.org/W2056279562, https://openalex.org/W4362522746, https://openalex.org/W2042017325, https://openalex.org/W2902434840, https://openalex.org/W2122868610, https://openalex.org/W6742022051, https://openalex.org/W2026006003, https://openalex.org/W2024655511, https://openalex.org/W1992113107, https://openalex.org/W2252358737, https://openalex.org/W2139838690, https://openalex.org/W1493169197, https://openalex.org/W1977431007, https://openalex.org/W155214824, https://openalex.org/W2066248085, https://openalex.org/W2139334262, https://openalex.org/W2139170292, https://openalex.org/W2057402599, https://openalex.org/W2119165463, https://openalex.org/W1995725210, https://openalex.org/W2095328153, https://openalex.org/W2065440772, https://openalex.org/W2039882053, https://openalex.org/W1996129886, https://openalex.org/W2565240503, https://openalex.org/W1976098918, https://openalex.org/W2285065014, https://openalex.org/W2592244930, https://openalex.org/W1487018400, https://openalex.org/W4249468678, https://openalex.org/W6605706638, https://openalex.org/W2102706345, https://openalex.org/W2024107363, https://openalex.org/W2081827377, https://openalex.org/W2741473715, https://openalex.org/W1993456360 |
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