Opportunities and challenges of upright patient positioning in radiotherapy Article Swipe
Lennart Volz
,
James Korte
,
Maria Chiara Martire
,
Ye Zhang
,
Nicholas Hardcastle
,
Marco Durante
,
Tomas Kron
,
Christian Graeff
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1088/1361-6560/ad70ee
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1088/1361-6560/ad70ee
Objective. Upright positioning has seen a surge in interest as a means to reduce radiotherapy (RT) cost, improve patient comfort, and, in selected cases, benefit treatment quality. In particle therapy (PT) in particular, eliminating the need for a gantry can present massive cost and facility footprint reduction. This review discusses the opportunities of upright RT in perspective of the open challenges. Approach. The clinical, technical, and workflow challenges that come with the upright posture have been extracted from an extensive literature review, and the current state of the art was collected in a synergistic perspective from photon and particle therapy. Considerations on future developments and opportunities are provided. Main results. Modern image guidance is paramount to upright RT, but it is not clear which modalities are essential to acquire in upright posture. Using upright MRI or upright CT, anatomical differences between upright/recumbent postures have been observed for nearly all body sites. Patient alignment similar to recumbent positioning was achieved in small patient/volunteer cohorts with prototype upright positioning systems. Possible clinical advantages, such as reduced breathing motion in upright position, have been reported, but limited cohort sizes prevent resilient conclusions on the treatment impact. Redesign of RT equipment for upright positioning, such as immobilization accessories for various body regions, is necessary, where several innovations were recently presented. Few clinical studies in upright PT have already reported promising outcomes for head&neck patients. Significance. With more evidence for benefits of upright RT emerging, several centers worldwide, particularly in PT, are installing upright positioning devices or have commenced upright treatment. Still, many challenges and open questions remain to be addressed to embed upright positioning firmly in the modern RT landscape. Guidelines, professionals trained in upright patient positioning, and large-scale clinical studies are required to bring upright RT to fruition.
Related Topics
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1088/1361-6560/ad70ee
- https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdf
- OA Status
- hybrid
- Cited By
- 11
- References
- 143
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4401689263
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4401689263Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1088/1361-6560/ad70eeDigital Object Identifier
- Title
-
Opportunities and challenges of upright patient positioning in radiotherapyWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-08-19Full publication date if available
- Authors
-
Lennart Volz, James Korte, Maria Chiara Martire, Ye Zhang, Nicholas Hardcastle, Marco Durante, Tomas Kron, Christian GraeffList of authors in order
- Landing page
-
https://doi.org/10.1088/1361-6560/ad70eePublisher landing page
- PDF URL
-
https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdfDirect OA link when available
- Concepts
-
Medical physics, Radiation therapy, Computer science, Medicine, RadiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
11Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 10, 2024: 1Per-year citation counts (last 5 years)
- References (count)
-
143Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4401689263 |
|---|---|
| doi | https://doi.org/10.1088/1361-6560/ad70ee |
| ids.doi | https://doi.org/10.1088/1361-6560/ad70ee |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/39159668 |
| ids.openalex | https://openalex.org/W4401689263 |
| fwci | 11.79325881 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D056888 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Patient Positioning |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D006801 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Humans |
| mesh[2].qualifier_ui | Q000379 |
| mesh[2].descriptor_ui | D011878 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | methods |
| mesh[2].descriptor_name | Radiotherapy |
| mesh[3].qualifier_ui | Q000295 |
| mesh[3].descriptor_ui | D011878 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | instrumentation |
| mesh[3].descriptor_name | Radiotherapy |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D056888 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Patient Positioning |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D006801 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Humans |
| mesh[6].qualifier_ui | Q000379 |
| mesh[6].descriptor_ui | D011878 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | methods |
| mesh[6].descriptor_name | Radiotherapy |
| mesh[7].qualifier_ui | Q000295 |
| mesh[7].descriptor_ui | D011878 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | instrumentation |
| mesh[7].descriptor_name | Radiotherapy |
| type | review |
| title | Opportunities and challenges of upright patient positioning in radiotherapy |
| biblio.issue | 18 |
| biblio.volume | 69 |
| biblio.last_page | 18TR02 |
| biblio.first_page | 18TR02 |
| grants[0].funder | https://openalex.org/F4320321114 |
| grants[0].award_id | 02NUK076 |
| grants[0].funder_display_name | Bundesministerium für Bildung und Forschung |
| grants[1].funder | https://openalex.org/F4320338338 |
| grants[1].award_id | 101008548 |
| grants[1].funder_display_name | H2020 Research Infrastructures |
| topics[0].id | https://openalex.org/T10358 |
| topics[0].field.id | https://openalex.org/fields/31 |
| topics[0].field.display_name | Physics and Astronomy |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/3108 |
| topics[0].subfield.display_name | Radiation |
| topics[0].display_name | Advanced Radiotherapy Techniques |
| topics[1].id | https://openalex.org/T11176 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9980999827384949 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2740 |
| topics[1].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[1].display_name | Radiation Therapy and Dosimetry |
| topics[2].id | https://openalex.org/T13123 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9710999727249146 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2741 |
| topics[2].subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| topics[2].display_name | Advances in Oncology and Radiotherapy |
| funders[0].id | https://openalex.org/F4320321114 |
| funders[0].ror | https://ror.org/04pz7b180 |
| funders[0].display_name | Bundesministerium für Bildung und Forschung |
| funders[1].id | https://openalex.org/F4320338338 |
| funders[1].ror | |
| funders[1].display_name | H2020 Research Infrastructures |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C19527891 |
| concepts[0].level | 1 |
| concepts[0].score | 0.5712625980377197 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1120908 |
| concepts[0].display_name | Medical physics |
| concepts[1].id | https://openalex.org/C509974204 |
| concepts[1].level | 2 |
| concepts[1].score | 0.5673807263374329 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q180507 |
| concepts[1].display_name | Radiation therapy |
| concepts[2].id | https://openalex.org/C41008148 |
| concepts[2].level | 0 |
| concepts[2].score | 0.39212337136268616 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[2].display_name | Computer science |
| concepts[3].id | https://openalex.org/C71924100 |
| concepts[3].level | 0 |
| concepts[3].score | 0.37315502762794495 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[3].display_name | Medicine |
| concepts[4].id | https://openalex.org/C126838900 |
| concepts[4].level | 1 |
| concepts[4].score | 0.3105056881904602 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q77604 |
| concepts[4].display_name | Radiology |
| keywords[0].id | https://openalex.org/keywords/medical-physics |
| keywords[0].score | 0.5712625980377197 |
| keywords[0].display_name | Medical physics |
| keywords[1].id | https://openalex.org/keywords/radiation-therapy |
| keywords[1].score | 0.5673807263374329 |
| keywords[1].display_name | Radiation therapy |
| keywords[2].id | https://openalex.org/keywords/computer-science |
| keywords[2].score | 0.39212337136268616 |
| keywords[2].display_name | Computer science |
| keywords[3].id | https://openalex.org/keywords/medicine |
| keywords[3].score | 0.37315502762794495 |
| keywords[3].display_name | Medicine |
| keywords[4].id | https://openalex.org/keywords/radiology |
| keywords[4].score | 0.3105056881904602 |
| keywords[4].display_name | Radiology |
| language | en |
| locations[0].id | doi:10.1088/1361-6560/ad70ee |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S20241394 |
| locations[0].source.issn | 0031-9155, 1361-6560 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0031-9155 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Physics in Medicine and Biology |
| locations[0].source.host_organization | https://openalex.org/P4310320083 |
| locations[0].source.host_organization_name | IOP Publishing |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320083 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Physics in Medicine & Biology |
| locations[0].landing_page_url | https://doi.org/10.1088/1361-6560/ad70ee |
| locations[1].id | pmid:39159668 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Physics in medicine and biology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/39159668 |
| locations[2].id | pmh:oai:dora:psi_66237 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306400127 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DORA Eawag (Swiss Federal Institute of Aquatic Science and Technology (Eawag)) |
| locations[2].source.host_organization | https://openalex.org/I63664421 |
| locations[2].source.host_organization_name | Swiss Federal Institute of Aquatic Science and Technology |
| locations[2].source.host_organization_lineage | https://openalex.org/I63664421 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | https://www.dora.lib4ri.ch/psi/islandora/object/psi%3A66237 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5004346141 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-0441-4350 |
| authorships[0].author.display_name | Lennart Volz |
| authorships[0].countries | DE |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I169556180 |
| authorships[0].affiliations[0].raw_affiliation_string | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| authorships[0].institutions[0].id | https://openalex.org/I169556180 |
| authorships[0].institutions[0].ror | https://ror.org/02k8cbn47 |
| authorships[0].institutions[0].type | facility |
| authorships[0].institutions[0].lineage | https://openalex.org/I1305996414, https://openalex.org/I169556180 |
| authorships[0].institutions[0].country_code | DE |
| authorships[0].institutions[0].display_name | GSI Helmholtz Centre for Heavy Ion Research |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Lennart Volz |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| authorships[1].author.id | https://openalex.org/A5056333681 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-9152-1319 |
| authorships[1].author.display_name | James Korte |
| authorships[1].countries | AU |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I2800555584 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Physical Science, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, Melbourne, Victoria, 3000, AUSTRALIA |
| authorships[1].institutions[0].id | https://openalex.org/I2800555584 |
| authorships[1].institutions[0].ror | https://ror.org/02a8bt934 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I2800555584 |
| authorships[1].institutions[0].country_code | AU |
| authorships[1].institutions[0].display_name | Peter MacCallum Cancer Centre |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | James Korte |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Physical Science, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, Melbourne, Victoria, 3000, AUSTRALIA |
| authorships[2].author.id | https://openalex.org/A5099082850 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Maria Chiara Martire |
| authorships[2].countries | DE |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I169556180 |
| authorships[2].affiliations[0].raw_affiliation_string | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| authorships[2].institutions[0].id | https://openalex.org/I169556180 |
| authorships[2].institutions[0].ror | https://ror.org/02k8cbn47 |
| authorships[2].institutions[0].type | facility |
| authorships[2].institutions[0].lineage | https://openalex.org/I1305996414, https://openalex.org/I169556180 |
| authorships[2].institutions[0].country_code | DE |
| authorships[2].institutions[0].display_name | GSI Helmholtz Centre for Heavy Ion Research |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Maria Chiara Martire |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| authorships[3].author.id | https://openalex.org/A5088018749 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-1608-4467 |
| authorships[3].author.display_name | Ye Zhang |
| authorships[3].countries | CH, MY |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I1341031431, https://openalex.org/I2802229908 |
| authorships[3].affiliations[0].raw_affiliation_string | Center for Proton Therapy, Paul Scherrer Institut, WMSA/C27.2, Villigen-PSI, 5232, SWITZERLAND |
| authorships[3].institutions[0].id | https://openalex.org/I2802229908 |
| authorships[3].institutions[0].ror | https://ror.org/03eh3y714 |
| authorships[3].institutions[0].type | facility |
| authorships[3].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I2802229908 |
| authorships[3].institutions[0].country_code | CH |
| authorships[3].institutions[0].display_name | Paul Scherrer Institute |
| authorships[3].institutions[1].id | https://openalex.org/I1341031431 |
| authorships[3].institutions[1].ror | https://ror.org/0053bzc32 |
| authorships[3].institutions[1].type | company |
| authorships[3].institutions[1].lineage | https://openalex.org/I1341031431 |
| authorships[3].institutions[1].country_code | MY |
| authorships[3].institutions[1].display_name | Proton (Malaysia) |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Ye Zhang |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Center for Proton Therapy, Paul Scherrer Institut, WMSA/C27.2, Villigen-PSI, 5232, SWITZERLAND |
| authorships[4].author.id | https://openalex.org/A5026836599 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-7796-8472 |
| authorships[4].author.display_name | Nicholas Hardcastle |
| authorships[4].countries | AU |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I2800555584 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Physical Science, Peter MacCallum Cancer Institute, 305 Grattan Street, Melbourne, Victoria, 3000, AUSTRALIA |
| authorships[4].institutions[0].id | https://openalex.org/I2800555584 |
| authorships[4].institutions[0].ror | https://ror.org/02a8bt934 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I2800555584 |
| authorships[4].institutions[0].country_code | AU |
| authorships[4].institutions[0].display_name | Peter MacCallum Cancer Centre |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Nicholas Hardcastle |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Physical Science, Peter MacCallum Cancer Institute, 305 Grattan Street, Melbourne, Victoria, 3000, AUSTRALIA |
| authorships[5].author.id | https://openalex.org/A5055277438 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-4615-553X |
| authorships[5].author.display_name | Marco Durante |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I169556180 |
| authorships[5].affiliations[0].raw_affiliation_string | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, 64291, GERMANY |
| authorships[5].institutions[0].id | https://openalex.org/I169556180 |
| authorships[5].institutions[0].ror | https://ror.org/02k8cbn47 |
| authorships[5].institutions[0].type | facility |
| authorships[5].institutions[0].lineage | https://openalex.org/I1305996414, https://openalex.org/I169556180 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | GSI Helmholtz Centre for Heavy Ion Research |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Marco Durante |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, 64291, GERMANY |
| authorships[6].author.id | https://openalex.org/A5038831861 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-5189-4046 |
| authorships[6].author.display_name | Tomas Kron |
| authorships[6].countries | AU |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I2800555584 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Physical Sciences , Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria 3000, Melbourne, Victoria, 3002, AUSTRALIA |
| authorships[6].institutions[0].id | https://openalex.org/I2800555584 |
| authorships[6].institutions[0].ror | https://ror.org/02a8bt934 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I2800555584 |
| authorships[6].institutions[0].country_code | AU |
| authorships[6].institutions[0].display_name | Peter MacCallum Cancer Centre |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Tomas Kron |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Physical Sciences , Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria 3000, Melbourne, Victoria, 3002, AUSTRALIA |
| authorships[7].author.id | https://openalex.org/A5014043673 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-5296-7649 |
| authorships[7].author.display_name | Christian Graeff |
| authorships[7].countries | DE |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I169556180 |
| authorships[7].affiliations[0].raw_affiliation_string | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| authorships[7].institutions[0].id | https://openalex.org/I169556180 |
| authorships[7].institutions[0].ror | https://ror.org/02k8cbn47 |
| authorships[7].institutions[0].type | facility |
| authorships[7].institutions[0].lineage | https://openalex.org/I1305996414, https://openalex.org/I169556180 |
| authorships[7].institutions[0].country_code | DE |
| authorships[7].institutions[0].display_name | GSI Helmholtz Centre for Heavy Ion Research |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Christian Graeff |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Biophysics, GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstr. 1, Darmstadt, Hessen, 64291, GERMANY |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdf |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Opportunities and challenges of upright patient positioning in radiotherapy |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10358 |
| primary_topic.field.id | https://openalex.org/fields/31 |
| primary_topic.field.display_name | Physics and Astronomy |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/3108 |
| primary_topic.subfield.display_name | Radiation |
| primary_topic.display_name | Advanced Radiotherapy Techniques |
| related_works | https://openalex.org/W4391375266, https://openalex.org/W2748952813, https://openalex.org/W3031052312, https://openalex.org/W4389568370, https://openalex.org/W3032375762, https://openalex.org/W1995515455, https://openalex.org/W2080531066, https://openalex.org/W3108674512, https://openalex.org/W1506200166, https://openalex.org/W1489783725 |
| cited_by_count | 11 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 10 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1088/1361-6560/ad70ee |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S20241394 |
| best_oa_location.source.issn | 0031-9155, 1361-6560 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0031-9155 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Physics in Medicine and Biology |
| best_oa_location.source.host_organization | https://openalex.org/P4310320083 |
| best_oa_location.source.host_organization_name | IOP Publishing |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320083 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Physics in Medicine & Biology |
| best_oa_location.landing_page_url | https://doi.org/10.1088/1361-6560/ad70ee |
| primary_location.id | doi:10.1088/1361-6560/ad70ee |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S20241394 |
| primary_location.source.issn | 0031-9155, 1361-6560 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0031-9155 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Physics in Medicine and Biology |
| primary_location.source.host_organization | https://openalex.org/P4310320083 |
| primary_location.source.host_organization_name | IOP Publishing |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320083 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://iopscience.iop.org/article/10.1088/1361-6560/ad70ee/pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Physics in Medicine & Biology |
| primary_location.landing_page_url | https://doi.org/10.1088/1361-6560/ad70ee |
| publication_date | 2024-08-19 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W2015593424, https://openalex.org/W6716181472, https://openalex.org/W2095918783, https://openalex.org/W6858044199, https://openalex.org/W2946043171, https://openalex.org/W2922205028, https://openalex.org/W3011101889, https://openalex.org/W2802141832, https://openalex.org/W2622576216, https://openalex.org/W2143101233, https://openalex.org/W3180846119, https://openalex.org/W2001834048, https://openalex.org/W4310261190, https://openalex.org/W4386957833, https://openalex.org/W3042398764, https://openalex.org/W3010754262, https://openalex.org/W2014911369, https://openalex.org/W2021347862, https://openalex.org/W2151792543, https://openalex.org/W4380987467, https://openalex.org/W2516454733, https://openalex.org/W4382631017, https://openalex.org/W4214894283, https://openalex.org/W2051222166, https://openalex.org/W1976750052, https://openalex.org/W3113217641, https://openalex.org/W1832300178, https://openalex.org/W3094399418, https://openalex.org/W4200052595, https://openalex.org/W4391359140, https://openalex.org/W3156494876, https://openalex.org/W4362721530, https://openalex.org/W4235748518, https://openalex.org/W3034637095, https://openalex.org/W3196663049, https://openalex.org/W2897613413, https://openalex.org/W2157004421, https://openalex.org/W2050955516, https://openalex.org/W4214918185, https://openalex.org/W3032404152, https://openalex.org/W1979871115, https://openalex.org/W2431505808, https://openalex.org/W3081423662, https://openalex.org/W2096210342, https://openalex.org/W2018819159, https://openalex.org/W2751276286, https://openalex.org/W1985065571, https://openalex.org/W2025507268, https://openalex.org/W4289080002, https://openalex.org/W2003320146, https://openalex.org/W2606112099, https://openalex.org/W2105874637, https://openalex.org/W1984282804, https://openalex.org/W4213073547, https://openalex.org/W3110168496, https://openalex.org/W4290879689, https://openalex.org/W4401534637, https://openalex.org/W3178514503, https://openalex.org/W2987665910, https://openalex.org/W2086479790, https://openalex.org/W2073859121, https://openalex.org/W3208496656, https://openalex.org/W3103424129, https://openalex.org/W3134098778, https://openalex.org/W4386198484, https://openalex.org/W2071775058, https://openalex.org/W3122546033, https://openalex.org/W2608768786, https://openalex.org/W2907953456, https://openalex.org/W3119346025, https://openalex.org/W4400624498, https://openalex.org/W3128093324, https://openalex.org/W4225303476, https://openalex.org/W2791042095, https://openalex.org/W2072547557, https://openalex.org/W1916536243, https://openalex.org/W3200666722, https://openalex.org/W2091021295, https://openalex.org/W2128284441, https://openalex.org/W2094010060, https://openalex.org/W1984184022, https://openalex.org/W3214968856, https://openalex.org/W2090095394, https://openalex.org/W4281639894, https://openalex.org/W2084851290, https://openalex.org/W4220942196, https://openalex.org/W2901762611, https://openalex.org/W4360603534, https://openalex.org/W4281478114, https://openalex.org/W2768776063, https://openalex.org/W3092193237, https://openalex.org/W3008534111, https://openalex.org/W2121136932, https://openalex.org/W4391513159, https://openalex.org/W2017529805, https://openalex.org/W4308652237, https://openalex.org/W7034195254, https://openalex.org/W4385230561, https://openalex.org/W4381598040, https://openalex.org/W4211256341, https://openalex.org/W1968212561, https://openalex.org/W2166018620, https://openalex.org/W1983281817, https://openalex.org/W1970033866, https://openalex.org/W3001888908, https://openalex.org/W2012825335, https://openalex.org/W2619544250, https://openalex.org/W3128633191, https://openalex.org/W1034765164, https://openalex.org/W6797475458, https://openalex.org/W1983586636, https://openalex.org/W4367309756, https://openalex.org/W2094826639, https://openalex.org/W2802172296, https://openalex.org/W2126680055, https://openalex.org/W2114521603, https://openalex.org/W4379421999, https://openalex.org/W4296635562, https://openalex.org/W4397043898, https://openalex.org/W4307773742, https://openalex.org/W2122062060, https://openalex.org/W2127729137, https://openalex.org/W3185044860, https://openalex.org/W4210690878, https://openalex.org/W6779053174, https://openalex.org/W2768280861, https://openalex.org/W6632513405, https://openalex.org/W2092760723, https://openalex.org/W6791609994, https://openalex.org/W3038166622, https://openalex.org/W3091002510, https://openalex.org/W4200424862, https://openalex.org/W2177891002, https://openalex.org/W4378800425, https://openalex.org/W2008373427, https://openalex.org/W3118397001, https://openalex.org/W3009865967, https://openalex.org/W4254965803, https://openalex.org/W3030682839, https://openalex.org/W3106189767, https://openalex.org/W1543414755, https://openalex.org/W3139091067, https://openalex.org/W2415841155 |
| referenced_works_count | 143 |
| abstract_inverted_index.a | 6, 11, 38, 93 |
| abstract_inverted_index.In | 28 |
| abstract_inverted_index.PT | 222 |
| abstract_inverted_index.RT | 55, 196, 239, 275, 293 |
| abstract_inverted_index.an | 79 |
| abstract_inverted_index.as | 10, 173, 202 |
| abstract_inverted_index.be | 265 |
| abstract_inverted_index.in | 8, 22, 32, 56, 92, 130, 160, 177, 220, 245, 272, 280 |
| abstract_inverted_index.is | 114, 121, 209 |
| abstract_inverted_index.it | 120 |
| abstract_inverted_index.of | 53, 58, 87, 195, 237 |
| abstract_inverted_index.on | 102, 190 |
| abstract_inverted_index.or | 136, 252 |
| abstract_inverted_index.to | 13, 116, 128, 155, 264, 267, 290, 294 |
| abstract_inverted_index.CT, | 138 |
| abstract_inverted_index.Few | 217 |
| abstract_inverted_index.MRI | 135 |
| abstract_inverted_index.PT, | 246 |
| abstract_inverted_index.RT, | 118 |
| abstract_inverted_index.The | 63 |
| abstract_inverted_index.all | 149 |
| abstract_inverted_index.and | 44, 66, 83, 98, 105, 260, 284 |
| abstract_inverted_index.are | 107, 126, 247, 288 |
| abstract_inverted_index.art | 89 |
| abstract_inverted_index.but | 119, 183 |
| abstract_inverted_index.can | 40 |
| abstract_inverted_index.for | 37, 147, 198, 205, 228, 235 |
| abstract_inverted_index.has | 4 |
| abstract_inverted_index.not | 122 |
| abstract_inverted_index.the | 35, 51, 59, 72, 84, 88, 191, 273 |
| abstract_inverted_index.was | 90, 158 |
| abstract_inverted_index.(PT) | 31 |
| abstract_inverted_index.(RT) | 16 |
| abstract_inverted_index.Main | 109 |
| abstract_inverted_index.This | 48 |
| abstract_inverted_index.With | 232 |
| abstract_inverted_index.and, | 21 |
| abstract_inverted_index.been | 76, 145, 181 |
| abstract_inverted_index.body | 150, 207 |
| abstract_inverted_index.come | 70 |
| abstract_inverted_index.cost | 43 |
| abstract_inverted_index.from | 78, 96 |
| abstract_inverted_index.have | 75, 144, 180, 223, 253 |
| abstract_inverted_index.many | 258 |
| abstract_inverted_index.more | 233 |
| abstract_inverted_index.need | 36 |
| abstract_inverted_index.open | 60, 261 |
| abstract_inverted_index.seen | 5 |
| abstract_inverted_index.such | 172, 201 |
| abstract_inverted_index.that | 69 |
| abstract_inverted_index.were | 214 |
| abstract_inverted_index.with | 71, 164 |
| abstract_inverted_index.Using | 133 |
| abstract_inverted_index.bring | 291 |
| abstract_inverted_index.clear | 123 |
| abstract_inverted_index.cost, | 17 |
| abstract_inverted_index.embed | 268 |
| abstract_inverted_index.image | 112 |
| abstract_inverted_index.means | 12 |
| abstract_inverted_index.sizes | 186 |
| abstract_inverted_index.small | 161 |
| abstract_inverted_index.state | 86 |
| abstract_inverted_index.surge | 7 |
| abstract_inverted_index.where | 211 |
| abstract_inverted_index.which | 124 |
| abstract_inverted_index.Modern | 111 |
| abstract_inverted_index.Still, | 257 |
| abstract_inverted_index.cases, | 24 |
| abstract_inverted_index.cohort | 185 |
| abstract_inverted_index.firmly | 271 |
| abstract_inverted_index.future | 103 |
| abstract_inverted_index.gantry | 39 |
| abstract_inverted_index.modern | 274 |
| abstract_inverted_index.motion | 176 |
| abstract_inverted_index.nearly | 148 |
| abstract_inverted_index.photon | 97 |
| abstract_inverted_index.reduce | 14 |
| abstract_inverted_index.remain | 263 |
| abstract_inverted_index.review | 49 |
| abstract_inverted_index.sites. | 151 |
| abstract_inverted_index.Patient | 152 |
| abstract_inverted_index.Upright | 2 |
| abstract_inverted_index.acquire | 129 |
| abstract_inverted_index.already | 224 |
| abstract_inverted_index.benefit | 25 |
| abstract_inverted_index.between | 141 |
| abstract_inverted_index.centers | 242 |
| abstract_inverted_index.cohorts | 163 |
| abstract_inverted_index.current | 85 |
| abstract_inverted_index.devices | 251 |
| abstract_inverted_index.impact. | 193 |
| abstract_inverted_index.improve | 18 |
| abstract_inverted_index.limited | 184 |
| abstract_inverted_index.massive | 42 |
| abstract_inverted_index.patient | 19, 282 |
| abstract_inverted_index.posture | 74 |
| abstract_inverted_index.present | 41 |
| abstract_inverted_index.prevent | 187 |
| abstract_inverted_index.reduced | 174 |
| abstract_inverted_index.review, | 82 |
| abstract_inverted_index.several | 212, 241 |
| abstract_inverted_index.similar | 154 |
| abstract_inverted_index.studies | 219, 287 |
| abstract_inverted_index.therapy | 30 |
| abstract_inverted_index.trained | 279 |
| abstract_inverted_index.upright | 54, 73, 117, 131, 134, 137, 166, 178, 199, 221, 238, 249, 255, 269, 281, 292 |
| abstract_inverted_index.various | 206 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Possible | 169 |
| abstract_inverted_index.Redesign | 194 |
| abstract_inverted_index.achieved | 159 |
| abstract_inverted_index.benefits | 236 |
| abstract_inverted_index.clinical | 170, 218, 286 |
| abstract_inverted_index.comfort, | 20 |
| abstract_inverted_index.evidence | 234 |
| abstract_inverted_index.facility | 45 |
| abstract_inverted_index.guidance | 113 |
| abstract_inverted_index.interest | 9 |
| abstract_inverted_index.observed | 146 |
| abstract_inverted_index.outcomes | 227 |
| abstract_inverted_index.particle | 29, 99 |
| abstract_inverted_index.posture. | 132 |
| abstract_inverted_index.postures | 143 |
| abstract_inverted_index.quality. | 27 |
| abstract_inverted_index.recently | 215 |
| abstract_inverted_index.regions, | 208 |
| abstract_inverted_index.reported | 225 |
| abstract_inverted_index.required | 289 |
| abstract_inverted_index.results. | 110 |
| abstract_inverted_index.selected | 23 |
| abstract_inverted_index.systems. | 168 |
| abstract_inverted_index.therapy. | 100 |
| abstract_inverted_index.workflow | 67 |
| abstract_inverted_index.Approach. | 62 |
| abstract_inverted_index.addressed | 266 |
| abstract_inverted_index.alignment | 153 |
| abstract_inverted_index.breathing | 175 |
| abstract_inverted_index.clinical, | 64 |
| abstract_inverted_index.collected | 91 |
| abstract_inverted_index.commenced | 254 |
| abstract_inverted_index.discusses | 50 |
| abstract_inverted_index.emerging, | 240 |
| abstract_inverted_index.equipment | 197 |
| abstract_inverted_index.essential | 127 |
| abstract_inverted_index.extensive | 80 |
| abstract_inverted_index.extracted | 77 |
| abstract_inverted_index.footprint | 46 |
| abstract_inverted_index.fruition. | 295 |
| abstract_inverted_index.paramount | 115 |
| abstract_inverted_index.patients. | 230 |
| abstract_inverted_index.position, | 179 |
| abstract_inverted_index.promising | 226 |
| abstract_inverted_index.prototype | 165 |
| abstract_inverted_index.provided. | 108 |
| abstract_inverted_index.questions | 262 |
| abstract_inverted_index.recumbent | 156 |
| abstract_inverted_index.reported, | 182 |
| abstract_inverted_index.resilient | 188 |
| abstract_inverted_index.treatment | 26, 192 |
| abstract_inverted_index.Objective. | 1 |
| abstract_inverted_index.anatomical | 139 |
| abstract_inverted_index.challenges | 68, 259 |
| abstract_inverted_index.installing | 248 |
| abstract_inverted_index.landscape. | 276 |
| abstract_inverted_index.literature | 81 |
| abstract_inverted_index.modalities | 125 |
| abstract_inverted_index.necessary, | 210 |
| abstract_inverted_index.presented. | 216 |
| abstract_inverted_index.reduction. | 47 |
| abstract_inverted_index.technical, | 65 |
| abstract_inverted_index.treatment. | 256 |
| abstract_inverted_index.worldwide, | 243 |
| abstract_inverted_index.Guidelines, | 277 |
| abstract_inverted_index.accessories | 204 |
| abstract_inverted_index.advantages, | 171 |
| abstract_inverted_index.challenges. | 61 |
| abstract_inverted_index.conclusions | 189 |
| abstract_inverted_index.differences | 140 |
| abstract_inverted_index.eliminating | 34 |
| abstract_inverted_index.innovations | 213 |
| abstract_inverted_index.large-scale | 285 |
| abstract_inverted_index.particular, | 33 |
| abstract_inverted_index.perspective | 57, 95 |
| abstract_inverted_index.positioning | 3, 157, 167, 250, 270 |
| abstract_inverted_index.synergistic | 94 |
| abstract_inverted_index.developments | 104 |
| abstract_inverted_index.particularly | 244 |
| abstract_inverted_index.positioning, | 200, 283 |
| abstract_inverted_index.radiotherapy | 15 |
| abstract_inverted_index.Significance. | 231 |
| abstract_inverted_index.head&neck | 229 |
| abstract_inverted_index.opportunities | 52, 106 |
| abstract_inverted_index.professionals | 278 |
| abstract_inverted_index.Considerations | 101 |
| abstract_inverted_index.immobilization | 203 |
| abstract_inverted_index.patient/volunteer | 162 |
| abstract_inverted_index.upright/recumbent | 142 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5004346141 |
| countries_distinct_count | 4 |
| institutions_distinct_count | 8 |
| corresponding_institution_ids | https://openalex.org/I169556180 |
| citation_normalized_percentile.value | 0.98717845 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |