Optimal Cutoff Values of Site-Specific Phase Angle for Predicting Independence in Activities of Daily Living in Post-stroke Patients Article Swipe
Yoshihiro Yoshimura
,
Hidetaka Wakabayashi
,
Fumihiko Nagano
,
Ayaka Matsumoto
,
Sayuri Shimazu
,
Ai Shiraishi
,
Yoshifumi Kido
,
Takahiro Bise
,
Takenori Hamada
,
Kouki Yoneda
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4235/agmr.25.0028
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4235/agmr.25.0028
Background: Phase angle (PhA) is a potential indicator of nutritional status and functional outcomes. However, optimal regional PhA cutoff values for predicting activities of daily living (ADL) post-stroke are unclear. We aimed to determine these cutoffs and assess whether PhA adds prognostic value to established clinical models.Methods: In this retrospective cohort study, stroke patients undergoing inpatient rehabilitation had body composition and PhA measured via multi-frequency bioelectrical impedance analysis. The primary outcome was ADL independence at discharge (motor Functional Independence Measure >78). Receiver operating characteristic (ROC) curves identified optimal PhA cutoffs; logistic regression assessed their predictive value, adjusting for confounders. Incremental discriminative ability was evaluated using area under the ROC curve (AUC) comparisons with DeLong’s test.Results: Among 1,080 patients (median age, 75.6 years; 54.1% men), optimal PhA cutoffs were: whole-body (women 3.90°, men 4.60°), non-paretic upper limb (4.45°, 4.90°), and non-paretic lower limb (4.00°, 4.80°). Higher PhA values above these cutoffs were independently associated with ADL independence (all p<0.05). Adding whole-body PhA to the baseline model improved AUC from 0.937 to 0.970 (ΔAUC=0.033; p=0.011); significant gains were observed for limb PhA.Conclusions: Optimal site-specific PhA cutoffs predict ADL independence at discharge in post-stroke patients. PhA provides significant incremental prognostic value beyond established clinical models, supporting its use in tailoring rehabilitation strategies.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4235/agmr.25.0028
- https://www.e-agmr.org/upload/pdf/agmr-25-0028.pdf
- OA Status
- diamond
- References
- 50
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413741144
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4413741144Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.4235/agmr.25.0028Digital Object Identifier
- Title
-
Optimal Cutoff Values of Site-Specific Phase Angle for Predicting Independence in Activities of Daily Living in Post-stroke PatientsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-08-27Full publication date if available
- Authors
-
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki YonedaList of authors in order
- Landing page
-
https://doi.org/10.4235/agmr.25.0028Publisher landing page
- PDF URL
-
https://www.e-agmr.org/upload/pdf/agmr-25-0028.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://www.e-agmr.org/upload/pdf/agmr-25-0028.pdfDirect OA link when available
- Concepts
-
Phase angle (astronomy), Cutoff, Independence (probability theory), Activities of daily living, Stroke (engine), Phase (matter), Physical medicine and rehabilitation, Medicine, Internal medicine, Statistics, Mathematics, Physical therapy, Physics, Optics, Thermodynamics, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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50Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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