Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia Article Swipe
Related Concepts
Deep brain stimulation
Dystonia
Cervical dystonia
Neuroscience
Subthalamic nucleus
Stimulation
Movement disorders
Basal ganglia
Connectome
Medicine
Psychology
Central nervous system
Parkinson's disease
Pathology
Functional connectivity
Disease
Andreas Horn
,
Martin M. Reich
,
Siobhán Ewert
,
Ningfei Li
,
Bassam Al‐Fatly
,
Florian Lange
,
Jonas Roothans
,
Simón Oxenford
,
Isabel Horn
,
Steffen Paschen
,
Joachim Runge
,
Fritz Wodarg
,
Karsten Witt
,
Robert Nickl
,
Matthias Wittstock
,
Gerd‐Helge Schneider
,
Philipp Mahlknecht
,
Werner Poewe
,
Wilhelm Eisner
,
Ann‐Kristin Helmers
,
Cordula Matthies
,
Joachim K. Krauss
,
Günther Deuschl
,
Jens Volkmann
,
Andrea A. Kühn
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1073/pnas.2114985119
· OA: W4220989613
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1073/pnas.2114985119
· OA: W4220989613
Significance We studied deep brain stimulation effects in two types of dystonia and conclude that different specific connections between the pallidum and thalamus are responsible for optimal treatment effects. Since alternative treatment options for dystonia beyond deep brain stimulation are scarce, our results will be crucial to maximize treatment outcome in this population of patients.
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