Optimization of ultrasonic-assisted extraction of bioactive compounds from Bupleuri Radix by response surface methodology and HPLC analysis Article Swipe
Jiachen Sun
,
Xuejiao Li
,
Zhuo Qu
,
Shengjie Dong
,
Huijun Zhao
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31665/jfb.2022.18321
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31665/jfb.2022.18321
A simple and efficient ultrasonic-assisted extraction of bioactive compounds from raw Bupleuri Radix and vinegar-baked Bupleuri Radix was developed and optimized by using quantitative analysis of multi-components by a single-marker combined with response surface methodology approaches. The quantitative analysis of multi-components by a single-marker analytical method based on high-performance liquid chromatography coupled with a photodiode array detector was established and applied to determine the contents of six bioactive compounds in raw Bupleuri Radix and vinegar-baked Bupleuri Radix. In order to maximize extraction of six bioactive compounds in raw Bupleuri Radix and vinegar-baked Bupleuri Radix, the ultrasonic-assisted extraction conditions were obtained by the response surface methodology coupled with Box–Behnken design. The conditions of ultrasonic-assisted extraction were found to be effective for the extraction of bioactive compounds from raw Bupleuri Radix and vinegar-baked Bupleuri Radix. The test results showed that the difference in saikosaponins contents in these samples was obvious; a quantitative analysis of saikosaponins will contribute significantly to improving the quality control of raw Bupleuri Radix and vinegar-baked Bupleuri Radix. In conclusion, the designed protocol is suitable for the quality control of raw Bupleuri Radix and vinegar-baked Bupleuri Radix.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.31665/jfb.2022.18321
- http://www.isnff-jfb.com/index.php/JFB/article/download/298/477
- OA Status
- diamond
- References
- 20
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4297988449
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4297988449Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.31665/jfb.2022.18321Digital Object Identifier
- Title
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Optimization of ultrasonic-assisted extraction of bioactive compounds from Bupleuri Radix by response surface methodology and HPLC analysisWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-09-30Full publication date if available
- Authors
-
Jiachen Sun, Xuejiao Li, Zhuo Qu, Shengjie Dong, Huijun ZhaoList of authors in order
- Landing page
-
https://doi.org/10.31665/jfb.2022.18321Publisher landing page
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https://www.isnff-jfb.com/index.php/JFB/article/download/298/477Direct link to full text PDF
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YesWhether a free full text is available
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-
diamondOpen access status per OpenAlex
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https://www.isnff-jfb.com/index.php/JFB/article/download/298/477Direct OA link when available
- Concepts
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Radix (gastropod), Chromatography, Extraction (chemistry), Raw material, High-performance liquid chromatography, Chemistry, Botany, Biology, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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20Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.contents | 64, 142 |
| abstract_inverted_index.designed | 172 |
| abstract_inverted_index.detector | 56 |
| abstract_inverted_index.maximize | 80 |
| abstract_inverted_index.obtained | 99 |
| abstract_inverted_index.obvious; | 147 |
| abstract_inverted_index.protocol | 173 |
| abstract_inverted_index.response | 32, 102 |
| abstract_inverted_index.suitable | 175 |
| abstract_inverted_index.bioactive | 7, 67, 84, 123 |
| abstract_inverted_index.compounds | 8, 68, 85, 124 |
| abstract_inverted_index.determine | 62 |
| abstract_inverted_index.developed | 18 |
| abstract_inverted_index.effective | 118 |
| abstract_inverted_index.efficient | 3 |
| abstract_inverted_index.improving | 157 |
| abstract_inverted_index.optimized | 20 |
| abstract_inverted_index.analytical | 44 |
| abstract_inverted_index.conditions | 97, 110 |
| abstract_inverted_index.contribute | 154 |
| abstract_inverted_index.difference | 139 |
| abstract_inverted_index.extraction | 5, 81, 96, 113, 121 |
| abstract_inverted_index.photodiode | 54 |
| abstract_inverted_index.approaches. | 35 |
| abstract_inverted_index.conclusion, | 170 |
| abstract_inverted_index.established | 58 |
| abstract_inverted_index.methodology | 34, 104 |
| abstract_inverted_index.quantitative | 23, 37, 149 |
| abstract_inverted_index.Box–Behnken | 107 |
| abstract_inverted_index.saikosaponins | 141, 152 |
| abstract_inverted_index.significantly | 155 |
| abstract_inverted_index.single-marker | 29, 43 |
| abstract_inverted_index.vinegar-baked | 14, 74, 91, 130, 166, 185 |
| abstract_inverted_index.chromatography | 50 |
| abstract_inverted_index.high-performance | 48 |
| abstract_inverted_index.multi-components | 26, 40 |
| abstract_inverted_index.ultrasonic-assisted | 4, 95, 112 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| citation_normalized_percentile.value | 0.11789072 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |