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Optimization of ultrasound-assisted extraction of (poly)phenolic compounds from blueberry (Vaccinium Myrtillus) leaves
July 2024 • Nebojša Vasilјević, Vlаdаn Мićić, Mitar Perušić, Marija Mitrović, Duško Kostić
The present paper aims to discover the optimal conditions for ultrasound-assisted extraction (UAE) of (poly)phenolic chemicals from blueberry (Vaccinium myrtillus) leaves. UAE was performed under the following process conditions: temperature: 25?65?C, ethanol concentration in the extraction solvent: 30?90 vol.%, and solid-to-solvent ratio: 1:15?1:45 w/v. Statistical analysis was performed using Design-Expert software, using the Box-Behnken design. The study''s responses were the content of total (poly)phenols, fla…
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