Oral hygiene care for critically ill children to prevent ventilator-associated pneumonia: a systematic review and meta-analysis Article Swipe
Hiroyuki Oikawa
,
Shotaro Nozaki
,
Munehiro Furuichi
,
Kentaro Tomita
,
Masayoshi Shinjoh
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.jhin.2025.05.007
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.jhin.2025.05.007
There is limited evidence on the effectiveness of oral hygiene care as part of the care bundle for preventing ventilator-associated pneumonia (VAP), particularly in children. The aim of this study was to assess whether the use of anti-infective agents in oral care can reduce the incidence of VAP in critically ill children. The systematic review and meta-analysis were conducted following PRISMA guidelines and registered with PROSPERO (CRD 42024508886). A systematic search of PubMed, CENTRAL, and Igaku Chuo Zasshi was performed in May 2024. Randomized controlled trials that evaluated oral hygiene interventions in critically ill children (≤18 years old) on mechanical ventilation for at least 48 h were included. Data were extracted independently by two reviewers, and the risk of bias was assessed. Meta-analysis was performed using a random-effects model. Five studies were included in the meta-analysis. The incidence of VAP, mortality, intensive care unit (ICU) stay duration, and mechanical ventilation duration were assessed. Oral hygiene procedures using antiseptics showed no significant difference in preventing VAP in critically ill children (risk ratio (RR) 0.95, 95% confidence interval (CI) 0.72-1.25). Similarly, there were no significant differences in mortality, ICU stay duration, or mechanical ventilation duration (RR 0.94, 95% CI 0.67-1.33; RR 2.02, 95% CI -0.87 to 4.91; and mean difference -1.01, 95% CI -2.35 to 0.33, respectively). This study found no evidence supporting the prevention of VAP through oral care in critically ill paediatric patients, although the evidence quality was low.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.jhin.2025.05.007
- https://www.journalofhospitalinfection.com/action/showPdf?pii=S0195670125001549
- OA Status
- hybrid
- References
- 38
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4410762919
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4410762919Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.jhin.2025.05.007Digital Object Identifier
- Title
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Oral hygiene care for critically ill children to prevent ventilator-associated pneumonia: a systematic review and meta-analysisWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-05-27Full publication date if available
- Authors
-
Hiroyuki Oikawa, Shotaro Nozaki, Munehiro Furuichi, Kentaro Tomita, Masayoshi ShinjohList of authors in order
- Landing page
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https://doi.org/10.1016/j.jhin.2025.05.007Publisher landing page
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https://www.journalofhospitalinfection.com/action/showPdf?pii=S0195670125001549Direct link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://www.journalofhospitalinfection.com/action/showPdf?pii=S0195670125001549Direct OA link when available
- Concepts
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Medicine, Ventilator-associated pneumonia, Intensive care medicine, Pneumonia, Critically ill, Meta-analysis, Hygiene, MEDLINE, Intensive care unit, Internal medicine, Political science, Law, PathologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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38Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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