Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer Article Swipe
Zhangxuan Shou
,
Xue Jin
,
Xujun He
,
Zhong‐Sheng Zhao
,
Yuan Chen
,
Meihua Ye
,
Jiong Yao
·
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.3892/ol.2017.5879
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.3892/ol.2017.5879
Musashi-1, an evolutionally conserved RNA-binding protein, has been implicated in the promotion of pathological stem cell proliferation, including tumorigenesis. The objective of the present study was to evaluate the expression of Musashi-1 protein and its implications in the progression and prognosis of gastric cancer. The expression level of Musashi-1 protein in gastric cancer was determined by western blotting and immunohistochemistry, and compared with the clinicopathological parameters. The present study revealed that the expression level of Musashi-1 protein in gastric cancer was significantly upregulated and correlated with the tumor size, tumor-node-metastasis (TNM) stage, Lauren classification, depth of invasion, vessel invasion, lymph node metastasis and distant metastasis. The mean survival time for patients with low expression levels of Musashi-1 was significantly longer compared with patients with high expression levels of Musashi-1. For each TNM stage, the mean survival time for patients with a low Musashi-1 expression levels was also significantly longer compared with patients with a high Musashi-1 expression level. Notably, TNM stage II patients with a low Musashi-1 expression level demonstrated a longer mean survival time compared with TNM stage I patients with high Musashi-1 expression level (56.8 vs. 42.3 months; P=0.001), and TNM stage III patients with low Musashi-1 expression level exhibited a longer mean survival time compared with TNM stage II patients with a high Musashi-1 expression level (44.0 vs. 33.8 months; P=0.034). Multivariate Cox's regression test demonstrated that Musashi-1 protein expression level was an independent prognostic indicator for the survival rate of the patients with gastric cancer. The results of the present study highlighted an important role for Musashi-1 protein in the progression of gastric cancer. The detection of the Musashi-1 protein expression level alone or in combination with TNM staging may aid the prediction of the prognosis of patients with gastric cancer.
Related Topics
Concepts
Oncogene
Cancer
Molecular medicine
Cell cycle
Cancer research
Medicine
Oncology
Internal medicine
Biology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3892/ol.2017.5879
- http://www.spandidos-publications.com/ol/13/5/3556/download
- OA Status
- diamond
- Cited By
- 15
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2599306999
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2599306999Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3892/ol.2017.5879Digital Object Identifier
- Title
-
Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancerWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2017Year of publication
- Publication date
-
2017-03-21Full publication date if available
- Authors
-
Zhangxuan Shou, Xue Jin, Xujun He, Zhong‐Sheng Zhao, Yuan Chen, Meihua Ye, Jiong YaoList of authors in order
- Landing page
-
https://doi.org/10.3892/ol.2017.5879Publisher landing page
- PDF URL
-
https://www.spandidos-publications.com/ol/13/5/3556/downloadDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://www.spandidos-publications.com/ol/13/5/3556/downloadDirect OA link when available
- Concepts
-
Oncogene, Cancer, Molecular medicine, Cell cycle, Cancer research, Medicine, Oncology, Internal medicine, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
15Total citation count in OpenAlex
- Citations by year (recent)
-
2023: 2, 2022: 3, 2021: 1, 2020: 2, 2019: 3Per-year citation counts (last 5 years)
- References (count)
-
55Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2599306999 |
|---|---|
| doi | https://doi.org/10.3892/ol.2017.5879 |
| ids.doi | https://doi.org/10.3892/ol.2017.5879 |
| ids.mag | 2599306999 |
| ids.openalex | https://openalex.org/W2599306999 |
| fwci | 1.91107115 |
| type | article |
| title | Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer |
| biblio.issue | 5 |
| biblio.volume | 13 |
| biblio.last_page | 3566 |
| biblio.first_page | 3556 |
| topics[0].id | https://openalex.org/T13199 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.977400004863739 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | Digestive system and related health |
| topics[1].id | https://openalex.org/T13437 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.975600004196167 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Mechanisms of cancer metastasis |
| topics[2].id | https://openalex.org/T12991 |
| topics[2].field.id | https://openalex.org/fields/11 |
| topics[2].field.display_name | Agricultural and Biological Sciences |
| topics[2].score | 0.9581999778747559 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1110 |
| topics[2].subfield.display_name | Plant Science |
| topics[2].display_name | Phytase and its Applications |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2781018059 |
| concepts[0].level | 4 |
| concepts[0].score | 0.8400434255599976 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q207609 |
| concepts[0].display_name | Oncogene |
| concepts[1].id | https://openalex.org/C121608353 |
| concepts[1].level | 2 |
| concepts[1].score | 0.8237929344177246 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q12078 |
| concepts[1].display_name | Cancer |
| concepts[2].id | https://openalex.org/C67082663 |
| concepts[2].level | 4 |
| concepts[2].score | 0.8069543838500977 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q3523816 |
| concepts[2].display_name | Molecular medicine |
| concepts[3].id | https://openalex.org/C29537977 |
| concepts[3].level | 3 |
| concepts[3].score | 0.6282951235771179 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q188941 |
| concepts[3].display_name | Cell cycle |
| concepts[4].id | https://openalex.org/C502942594 |
| concepts[4].level | 1 |
| concepts[4].score | 0.5391064286231995 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q3421914 |
| concepts[4].display_name | Cancer research |
| concepts[5].id | https://openalex.org/C71924100 |
| concepts[5].level | 0 |
| concepts[5].score | 0.48327189683914185 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[5].display_name | Medicine |
| concepts[6].id | https://openalex.org/C143998085 |
| concepts[6].level | 1 |
| concepts[6].score | 0.3859630525112152 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q162555 |
| concepts[6].display_name | Oncology |
| concepts[7].id | https://openalex.org/C126322002 |
| concepts[7].level | 1 |
| concepts[7].score | 0.3486200273036957 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[7].display_name | Internal medicine |
| concepts[8].id | https://openalex.org/C86803240 |
| concepts[8].level | 0 |
| concepts[8].score | 0.3333872854709625 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[8].display_name | Biology |
| keywords[0].id | https://openalex.org/keywords/oncogene |
| keywords[0].score | 0.8400434255599976 |
| keywords[0].display_name | Oncogene |
| keywords[1].id | https://openalex.org/keywords/cancer |
| keywords[1].score | 0.8237929344177246 |
| keywords[1].display_name | Cancer |
| keywords[2].id | https://openalex.org/keywords/molecular-medicine |
| keywords[2].score | 0.8069543838500977 |
| keywords[2].display_name | Molecular medicine |
| keywords[3].id | https://openalex.org/keywords/cell-cycle |
| keywords[3].score | 0.6282951235771179 |
| keywords[3].display_name | Cell cycle |
| keywords[4].id | https://openalex.org/keywords/cancer-research |
| keywords[4].score | 0.5391064286231995 |
| keywords[4].display_name | Cancer research |
| keywords[5].id | https://openalex.org/keywords/medicine |
| keywords[5].score | 0.48327189683914185 |
| keywords[5].display_name | Medicine |
| keywords[6].id | https://openalex.org/keywords/oncology |
| keywords[6].score | 0.3859630525112152 |
| keywords[6].display_name | Oncology |
| keywords[7].id | https://openalex.org/keywords/internal-medicine |
| keywords[7].score | 0.3486200273036957 |
| keywords[7].display_name | Internal medicine |
| keywords[8].id | https://openalex.org/keywords/biology |
| keywords[8].score | 0.3333872854709625 |
| keywords[8].display_name | Biology |
| language | en |
| locations[0].id | doi:10.3892/ol.2017.5879 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S58832373 |
| locations[0].source.issn | 1792-1074, 1792-1082 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1792-1074 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Oncology Letters |
| locations[0].source.host_organization | https://openalex.org/P4310320412 |
| locations[0].source.host_organization_name | Spandidos Publishing |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320412 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | http://www.spandidos-publications.com/ol/13/5/3556/download |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Oncology Letters |
| locations[0].landing_page_url | https://doi.org/10.3892/ol.2017.5879 |
| locations[1].id | pmh:oai:europepmc.org:4284027 |
| locations[1].is_oa | True |
| locations[1].source.id | https://openalex.org/S4306400806 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | Europe PMC (PubMed Central) |
| locations[1].source.host_organization | https://openalex.org/I1303153112 |
| locations[1].source.host_organization_name | European Bioinformatics Institute |
| locations[1].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[1].license | other-oa |
| locations[1].pdf_url | |
| locations[1].version | submittedVersion |
| locations[1].raw_type | Text |
| locations[1].license_id | https://openalex.org/licenses/other-oa |
| locations[1].is_accepted | False |
| locations[1].is_published | False |
| locations[1].raw_source_name | |
| locations[1].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/5431268 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:5431268 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | http://doi.org/10.3892/ol.2017.5879 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5033722307 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-6019-9320 |
| authorships[0].author.display_name | Zhangxuan Shou |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Pharmaceutical Sciences, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[0].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[0].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Hangzhou Medical College |
| authorships[0].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[0].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[0].institutions[1].type | healthcare |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[0].institutions[1].country_code | CN |
| authorships[0].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Zhangxuan Shou |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Pharmaceutical Sciences, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[1].author.id | https://openalex.org/A5100694785 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-9388-0558 |
| authorships[1].author.display_name | Xue Jin |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Pharmaceutical Sciences, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[1].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[1].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Hangzhou Medical College |
| authorships[1].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[1].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[1].institutions[1].type | healthcare |
| authorships[1].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[1].institutions[1].country_code | CN |
| authorships[1].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Xue Jin |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Pharmaceutical Sciences, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[2].author.id | https://openalex.org/A5100715896 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-6979-2072 |
| authorships[2].author.display_name | Xujun He |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[2].affiliations[0].raw_affiliation_string | Key Laboratory of Gastroenterology of Zhejiang, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[2].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[2].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Hangzhou Medical College |
| authorships[2].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[2].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[2].institutions[1].type | healthcare |
| authorships[2].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[2].institutions[1].country_code | CN |
| authorships[2].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Xujun He |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Key Laboratory of Gastroenterology of Zhejiang, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[3].author.id | https://openalex.org/A5100962744 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Zhong‐Sheng Zhao |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[3].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[3].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Hangzhou Medical College |
| authorships[3].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[3].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[3].institutions[1].type | healthcare |
| authorships[3].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[3].institutions[1].country_code | CN |
| authorships[3].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Zhongsheng Zhao |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[4].author.id | https://openalex.org/A5100400907 |
| authorships[4].author.orcid | https://orcid.org/0009-0008-7270-7669 |
| authorships[4].author.display_name | Yuan Chen |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[4].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[4].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Hangzhou Medical College |
| authorships[4].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[4].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[4].institutions[1].type | healthcare |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[4].institutions[1].country_code | CN |
| authorships[4].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Yuan Chen |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[5].author.id | https://openalex.org/A5089961977 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Meihua Ye |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[5].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[5].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Hangzhou Medical College |
| authorships[5].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[5].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[5].institutions[1].type | healthcare |
| authorships[5].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[5].institutions[1].country_code | CN |
| authorships[5].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Meihua Ye |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[6].author.id | https://openalex.org/A5065211659 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Jiong Yao |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210131061, https://openalex.org/I4210165441 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Medical Records and Statistics, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| authorships[6].institutions[0].id | https://openalex.org/I4210165441 |
| authorships[6].institutions[0].ror | https://ror.org/05gpas306 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210165441 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | Hangzhou Medical College |
| authorships[6].institutions[1].id | https://openalex.org/I4210131061 |
| authorships[6].institutions[1].ror | https://ror.org/03k14e164 |
| authorships[6].institutions[1].type | healthcare |
| authorships[6].institutions[1].lineage | https://openalex.org/I4210131061 |
| authorships[6].institutions[1].country_code | CN |
| authorships[6].institutions[1].display_name | Zhejiang Provincial People's Hospital |
| authorships[6].author_position | last |
| authorships[6].raw_author_name | Jiong Yao |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Medical Records and Statistics, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | http://www.spandidos-publications.com/ol/13/5/3556/download |
| open_access.oa_status | diamond |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T13199 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.977400004863739 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | Digestive system and related health |
| related_works | https://openalex.org/W2396096014, https://openalex.org/W1990949341, https://openalex.org/W2953866084, https://openalex.org/W2165801694, https://openalex.org/W2905335103, https://openalex.org/W2011967628, https://openalex.org/W2790934887, https://openalex.org/W2020643427, https://openalex.org/W2967566052, https://openalex.org/W3161809393 |
| cited_by_count | 15 |
| counts_by_year[0].year | 2023 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2022 |
| counts_by_year[1].cited_by_count | 3 |
| counts_by_year[2].year | 2021 |
| counts_by_year[2].cited_by_count | 1 |
| counts_by_year[3].year | 2020 |
| counts_by_year[3].cited_by_count | 2 |
| counts_by_year[4].year | 2019 |
| counts_by_year[4].cited_by_count | 3 |
| counts_by_year[5].year | 2018 |
| counts_by_year[5].cited_by_count | 4 |
| locations_count | 3 |
| best_oa_location.id | doi:10.3892/ol.2017.5879 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S58832373 |
| best_oa_location.source.issn | 1792-1074, 1792-1082 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1792-1074 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Oncology Letters |
| best_oa_location.source.host_organization | https://openalex.org/P4310320412 |
| best_oa_location.source.host_organization_name | Spandidos Publishing |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320412 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | http://www.spandidos-publications.com/ol/13/5/3556/download |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Oncology Letters |
| best_oa_location.landing_page_url | https://doi.org/10.3892/ol.2017.5879 |
| primary_location.id | doi:10.3892/ol.2017.5879 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S58832373 |
| primary_location.source.issn | 1792-1074, 1792-1082 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1792-1074 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Oncology Letters |
| primary_location.source.host_organization | https://openalex.org/P4310320412 |
| primary_location.source.host_organization_name | Spandidos Publishing |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320412 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | http://www.spandidos-publications.com/ol/13/5/3556/download |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Oncology Letters |
| primary_location.landing_page_url | https://doi.org/10.3892/ol.2017.5879 |
| publication_date | 2017-03-21 |
| publication_year | 2017 |
| referenced_works | https://openalex.org/W2917837889, https://openalex.org/W2078531409, https://openalex.org/W6817627161, https://openalex.org/W2016681720, https://openalex.org/W55148864, https://openalex.org/W2094647555, https://openalex.org/W1534578968, https://openalex.org/W2116504531, https://openalex.org/W2056936400, https://openalex.org/W2055624537, https://openalex.org/W2069584695, https://openalex.org/W1981339505, https://openalex.org/W1525061042, https://openalex.org/W1998760200, https://openalex.org/W2088116141, https://openalex.org/W1495997023, https://openalex.org/W2002715625, https://openalex.org/W2056890533, https://openalex.org/W2098016561, https://openalex.org/W326726202, https://openalex.org/W2007740937, https://openalex.org/W2102270036, https://openalex.org/W2074319412, https://openalex.org/W1990877484, https://openalex.org/W2086181345, https://openalex.org/W2338576041, https://openalex.org/W2043473139, https://openalex.org/W2062059217, https://openalex.org/W2007822205, https://openalex.org/W2102624283, https://openalex.org/W2084316080, https://openalex.org/W1826852120, https://openalex.org/W2109102096, https://openalex.org/W2148721757, https://openalex.org/W1601336165, https://openalex.org/W2053924952, https://openalex.org/W918724226, https://openalex.org/W1779083940, https://openalex.org/W1985120655, https://openalex.org/W2009606787, https://openalex.org/W2077927052, https://openalex.org/W2008390728, https://openalex.org/W2164236082, https://openalex.org/W1842717721, https://openalex.org/W2124255030, https://openalex.org/W2152569910, https://openalex.org/W2112535346, https://openalex.org/W1978124642, https://openalex.org/W1973397682, https://openalex.org/W1578083272, https://openalex.org/W4236250701, https://openalex.org/W2032326904, https://openalex.org/W4238820556, https://openalex.org/W4212866204, https://openalex.org/W4239689108 |
| referenced_works_count | 55 |
| abstract_inverted_index.I | 179 |
| abstract_inverted_index.a | 140, 153, 164, 170, 202, 214 |
| abstract_inverted_index.II | 161, 211 |
| abstract_inverted_index.an | 1, 235, 256 |
| abstract_inverted_index.by | 55 |
| abstract_inverted_index.in | 9, 36, 50, 77, 262, 278 |
| abstract_inverted_index.of | 12, 21, 30, 41, 47, 74, 95, 115, 127, 243, 251, 265, 270, 287, 290 |
| abstract_inverted_index.or | 277 |
| abstract_inverted_index.to | 26 |
| abstract_inverted_index.For | 129 |
| abstract_inverted_index.III | 194 |
| abstract_inverted_index.TNM | 131, 159, 177, 192, 209, 281 |
| abstract_inverted_index.The | 19, 44, 66, 105, 249, 268 |
| abstract_inverted_index.aid | 284 |
| abstract_inverted_index.and | 33, 39, 58, 60, 83, 102, 191 |
| abstract_inverted_index.for | 109, 137, 239, 259 |
| abstract_inverted_index.has | 6 |
| abstract_inverted_index.its | 34 |
| abstract_inverted_index.low | 112, 141, 165, 197 |
| abstract_inverted_index.may | 283 |
| abstract_inverted_index.the | 10, 22, 28, 37, 63, 71, 86, 133, 240, 244, 252, 263, 271, 285, 288 |
| abstract_inverted_index.vs. | 187, 220 |
| abstract_inverted_index.was | 25, 53, 80, 117, 145, 234 |
| abstract_inverted_index.33.8 | 221 |
| abstract_inverted_index.42.3 | 188 |
| abstract_inverted_index.also | 146 |
| abstract_inverted_index.been | 7 |
| abstract_inverted_index.cell | 15 |
| abstract_inverted_index.each | 130 |
| abstract_inverted_index.high | 124, 154, 182, 215 |
| abstract_inverted_index.mean | 106, 134, 172, 204 |
| abstract_inverted_index.node | 100 |
| abstract_inverted_index.rate | 242 |
| abstract_inverted_index.role | 258 |
| abstract_inverted_index.stem | 14 |
| abstract_inverted_index.test | 227 |
| abstract_inverted_index.that | 70, 229 |
| abstract_inverted_index.time | 108, 136, 174, 206 |
| abstract_inverted_index.with | 62, 85, 111, 121, 123, 139, 150, 152, 163, 176, 181, 196, 208, 213, 246, 280, 292 |
| abstract_inverted_index.(44.0 | 219 |
| abstract_inverted_index.(56.8 | 186 |
| abstract_inverted_index.(TNM) | 90 |
| abstract_inverted_index.Cox's | 225 |
| abstract_inverted_index.alone | 276 |
| abstract_inverted_index.depth | 94 |
| abstract_inverted_index.level | 46, 73, 168, 185, 200, 218, 233, 275 |
| abstract_inverted_index.lymph | 99 |
| abstract_inverted_index.size, | 88 |
| abstract_inverted_index.stage | 160, 178, 193, 210 |
| abstract_inverted_index.study | 24, 68, 254 |
| abstract_inverted_index.tumor | 87 |
| abstract_inverted_index.Lauren | 92 |
| abstract_inverted_index.cancer | 52, 79 |
| abstract_inverted_index.level. | 157 |
| abstract_inverted_index.levels | 114, 126, 144 |
| abstract_inverted_index.longer | 119, 148, 171, 203 |
| abstract_inverted_index.stage, | 91, 132 |
| abstract_inverted_index.vessel | 97 |
| abstract_inverted_index.cancer. | 43, 248, 267, 294 |
| abstract_inverted_index.distant | 103 |
| abstract_inverted_index.gastric | 42, 51, 78, 247, 266, 293 |
| abstract_inverted_index.months; | 189, 222 |
| abstract_inverted_index.present | 23, 67, 253 |
| abstract_inverted_index.protein | 32, 49, 76, 231, 261, 273 |
| abstract_inverted_index.results | 250 |
| abstract_inverted_index.staging | 282 |
| abstract_inverted_index.western | 56 |
| abstract_inverted_index.Notably, | 158 |
| abstract_inverted_index.blotting | 57 |
| abstract_inverted_index.compared | 61, 120, 149, 175, 207 |
| abstract_inverted_index.evaluate | 27 |
| abstract_inverted_index.patients | 110, 122, 138, 151, 162, 180, 195, 212, 245, 291 |
| abstract_inverted_index.protein, | 5 |
| abstract_inverted_index.revealed | 69 |
| abstract_inverted_index.survival | 107, 135, 173, 205, 241 |
| abstract_inverted_index.Musashi-1 | 31, 48, 75, 116, 142, 155, 166, 183, 198, 216, 230, 260, 272 |
| abstract_inverted_index.P=0.001), | 190 |
| abstract_inverted_index.P=0.034). | 223 |
| abstract_inverted_index.conserved | 3 |
| abstract_inverted_index.detection | 269 |
| abstract_inverted_index.exhibited | 201 |
| abstract_inverted_index.important | 257 |
| abstract_inverted_index.including | 17 |
| abstract_inverted_index.indicator | 238 |
| abstract_inverted_index.invasion, | 96, 98 |
| abstract_inverted_index.objective | 20 |
| abstract_inverted_index.prognosis | 40, 289 |
| abstract_inverted_index.promotion | 11 |
| abstract_inverted_index.Musashi-1, | 0 |
| abstract_inverted_index.Musashi-1. | 128 |
| abstract_inverted_index.correlated | 84 |
| abstract_inverted_index.determined | 54 |
| abstract_inverted_index.expression | 29, 45, 72, 113, 125, 143, 156, 167, 184, 199, 217, 232, 274 |
| abstract_inverted_index.implicated | 8 |
| abstract_inverted_index.metastasis | 101 |
| abstract_inverted_index.prediction | 286 |
| abstract_inverted_index.prognostic | 237 |
| abstract_inverted_index.regression | 226 |
| abstract_inverted_index.RNA-binding | 4 |
| abstract_inverted_index.combination | 279 |
| abstract_inverted_index.highlighted | 255 |
| abstract_inverted_index.independent | 236 |
| abstract_inverted_index.metastasis. | 104 |
| abstract_inverted_index.parameters. | 65 |
| abstract_inverted_index.progression | 38, 264 |
| abstract_inverted_index.upregulated | 82 |
| abstract_inverted_index.Multivariate | 224 |
| abstract_inverted_index.demonstrated | 169, 228 |
| abstract_inverted_index.implications | 35 |
| abstract_inverted_index.pathological | 13 |
| abstract_inverted_index.evolutionally | 2 |
| abstract_inverted_index.significantly | 81, 118, 147 |
| abstract_inverted_index.proliferation, | 16 |
| abstract_inverted_index.tumorigenesis. | 18 |
| abstract_inverted_index.classification, | 93 |
| abstract_inverted_index.clinicopathological | 64 |
| abstract_inverted_index.immunohistochemistry, | 59 |
| abstract_inverted_index.tumor-node-metastasis | 89 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 7 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/1 |
| sustainable_development_goals[0].score | 0.5099999904632568 |
| sustainable_development_goals[0].display_name | No poverty |
| citation_normalized_percentile.value | 0.86079565 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |