P-90 Prognostic impact of depth of response (DpR) and early tumour shrinkage (ETS) in patients (pts) with BRAFV600E mutated (mut) metastatic colorectal cancer (mCRC) receiving targeted therapy (TT) as second-line treatment Article Swipe

PDF

Guglielmo Vetere , Marco Maria Germani , Maria Bensi , Carlotta Antoniotti , Sara Lonardi , Alessandro Passardi , Filippo Ghelardi , Maria Alessandra Calegari , Beatrice Borelli , S. Santucci , Rossana Intini , Eleonora Cristarella , Mara Persano , Alberto Puccini , Daniele Lavacchi , Leonardo Noto , Clizia Zichi , Riccardo Giampieri , Massimiliano Salati , Chiara Cremolini ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1016/j.annonc.2023.04.146

Related Topics

Concepts

Medicine Stain Colorectal cancer Immunohistochemistry Internal medicine Pathology Staining Cancer Oncology

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.annonc.2023.04.146
PDF: http://www.annalsofoncology.org/article/S0923753423002880/pdf
OA Status: bronze
Cited By: 3
References: 1
Related Works: 10
OpenAlex ID: https://openalex.org/W4382799245

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W4382799245

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.annonc.2023.04.146

Digital Object Identifier
Title: P-90 Prognostic impact of depth of response (DpR) and early tumour shrinkage (ETS) in patients (pts) with BRAFV600E mutated (mut) metastatic colorectal cancer (mCRC) receiving targeted therapy (TT) as second-line treatment

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2023

Year of publication
Publication date: 2023-06-01

Full publication date if available
Authors: Guglielmo Vetere, Marco Maria Germani, Maria Bensi, Carlotta Antoniotti, Sara Lonardi, Alessandro Passardi, Filippo Ghelardi, Maria Alessandra Calegari, Beatrice Borelli, S. Santucci, Rossana Intini, Eleonora Cristarella, Mara Persano, Alberto Puccini, Daniele Lavacchi, Leonardo Noto, Clizia Zichi, Riccardo Giampieri, Massimiliano Salati, Chiara Cremolini

List of authors in order
Landing page: https://doi.org/10.1016/j.annonc.2023.04.146

Publisher landing page
PDF URL: https://www.annalsofoncology.org/article/S0923753423002880/pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: bronze

Open access status per OpenAlex
OA URL: https://www.annalsofoncology.org/article/S0923753423002880/pdf

Direct OA link when available
Concepts: Medicine, Stain, Colorectal cancer, Immunohistochemistry, Internal medicine, Pathology, Staining, Cancer, Oncology

Top concepts (fields/topics) attached by OpenAlex
Cited by: 3

Total citation count in OpenAlex
Citations by year (recent): 2023: 3

Per-year citation counts (last 5 years)
References (count): 1

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W4382799245
doi	https://doi.org/10.1016/j.annonc.2023.04.146
ids.doi	https://doi.org/10.1016/j.annonc.2023.04.146
ids.openalex	https://openalex.org/W4382799245
fwci	0.71279108
type	article
title	P-90 Prognostic impact of depth of response (DpR) and early tumour shrinkage (ETS) in patients (pts) with BRAFV600E mutated (mut) metastatic colorectal cancer (mCRC) receiving targeted therapy (TT) as second-line treatment
biblio.issue
biblio.volume	34
biblio.last_page	S45
biblio.first_page	S45
topics[0].id	https://openalex.org/T11067
topics[0].field.id	https://openalex.org/fields/27
topics[0].field.display_name	Medicine
topics[0].score	0.9959999918937683
topics[0].domain.id	https://openalex.org/domains/4
topics[0].domain.display_name	Health Sciences
topics[0].subfield.id	https://openalex.org/subfields/2730
topics[0].subfield.display_name	Oncology
topics[0].display_name	Colorectal Cancer Treatments and Studies
topics[1].id	https://openalex.org/T11287
topics[1].field.id	https://openalex.org/fields/13
topics[1].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[1].score	0.9948999881744385
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/1306
topics[1].subfield.display_name	Cancer Research
topics[1].display_name	Cancer Genomics and Diagnostics
topics[2].id	https://openalex.org/T10158
topics[2].field.id	https://openalex.org/fields/27
topics[2].field.display_name	Medicine
topics[2].score	0.9861000180244446
topics[2].domain.id	https://openalex.org/domains/4
topics[2].domain.display_name	Health Sciences
topics[2].subfield.id	https://openalex.org/subfields/2730
topics[2].subfield.display_name	Oncology
topics[2].display_name	Cancer Immunotherapy and Biomarkers
is_xpac	False
apc_list.value	4060
apc_list.currency	USD
apc_list.value_usd	4060
apc_paid
concepts[0].id	https://openalex.org/C71924100
concepts[0].level	0
concepts[0].score	0.8941231966018677
concepts[0].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[0].display_name	Medicine
concepts[1].id	https://openalex.org/C2781294515
concepts[1].level	3
concepts[1].score	0.54904705286026
concepts[1].wikidata	https://www.wikidata.org/wiki/Q2733470
concepts[1].display_name	Stain
concepts[2].id	https://openalex.org/C526805850
concepts[2].level	3
concepts[2].score	0.522427499294281
concepts[2].wikidata	https://www.wikidata.org/wiki/Q188874
concepts[2].display_name	Colorectal cancer
concepts[3].id	https://openalex.org/C204232928
concepts[3].level	2
concepts[3].score	0.5022215843200684
concepts[3].wikidata	https://www.wikidata.org/wiki/Q899285
concepts[3].display_name	Immunohistochemistry
concepts[4].id	https://openalex.org/C126322002
concepts[4].level	1
concepts[4].score	0.42824649810791016
concepts[4].wikidata	https://www.wikidata.org/wiki/Q11180
concepts[4].display_name	Internal medicine
concepts[5].id	https://openalex.org/C142724271
concepts[5].level	1
concepts[5].score	0.4270324409008026
concepts[5].wikidata	https://www.wikidata.org/wiki/Q7208
concepts[5].display_name	Pathology
concepts[6].id	https://openalex.org/C74864618
concepts[6].level	2
concepts[6].score	0.41546523571014404
concepts[6].wikidata	https://www.wikidata.org/wiki/Q2332446
concepts[6].display_name	Staining
concepts[7].id	https://openalex.org/C121608353
concepts[7].level	2
concepts[7].score	0.3928799033164978
concepts[7].wikidata	https://www.wikidata.org/wiki/Q12078
concepts[7].display_name	Cancer
concepts[8].id	https://openalex.org/C143998085
concepts[8].level	1
concepts[8].score	0.32748281955718994
concepts[8].wikidata	https://www.wikidata.org/wiki/Q162555
concepts[8].display_name	Oncology
keywords[0].id	https://openalex.org/keywords/medicine
keywords[0].score	0.8941231966018677
keywords[0].display_name	Medicine
keywords[1].id	https://openalex.org/keywords/stain
keywords[1].score	0.54904705286026
keywords[1].display_name	Stain
keywords[2].id	https://openalex.org/keywords/colorectal-cancer
keywords[2].score	0.522427499294281
keywords[2].display_name	Colorectal cancer
keywords[3].id	https://openalex.org/keywords/immunohistochemistry
keywords[3].score	0.5022215843200684
keywords[3].display_name	Immunohistochemistry
keywords[4].id	https://openalex.org/keywords/internal-medicine
keywords[4].score	0.42824649810791016
keywords[4].display_name	Internal medicine
keywords[5].id	https://openalex.org/keywords/pathology
keywords[5].score	0.4270324409008026
keywords[5].display_name	Pathology
keywords[6].id	https://openalex.org/keywords/staining
keywords[6].score	0.41546523571014404
keywords[6].display_name	Staining
keywords[7].id	https://openalex.org/keywords/cancer
keywords[7].score	0.3928799033164978
keywords[7].display_name	Cancer
keywords[8].id	https://openalex.org/keywords/oncology
keywords[8].score	0.32748281955718994
keywords[8].display_name	Oncology
language	en
locations[0].id	doi:10.1016/j.annonc.2023.04.146
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S41454044
locations[0].source.issn	0923-7534, 1569-8041
locations[0].source.type	journal
locations[0].source.is_oa	False
locations[0].source.issn_l	0923-7534
locations[0].source.is_core	True
locations[0].source.is_in_doaj	False
locations[0].source.display_name	Annals of Oncology
locations[0].source.host_organization	https://openalex.org/P4310320990
locations[0].source.host_organization_name	Elsevier BV
locations[0].source.host_organization_lineage	https://openalex.org/P4310320990
locations[0].license	publisher-specific-oa
locations[0].pdf_url	http://www.annalsofoncology.org/article/S0923753423002880/pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id	https://openalex.org/licenses/publisher-specific-oa
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Annals of Oncology
locations[0].landing_page_url	https://doi.org/10.1016/j.annonc.2023.04.146
indexed_in	crossref
authorships[0].author.id	https://openalex.org/A5031596792
authorships[0].author.orcid	https://orcid.org/0000-0001-6943-2897
authorships[0].author.display_name	Guglielmo Vetere
authorships[0].countries	IT
authorships[0].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[0].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[0].institutions[0].id	https://openalex.org/I4210165410
authorships[0].institutions[0].ror	https://ror.org/05xrcj819
authorships[0].institutions[0].type	healthcare
authorships[0].institutions[0].lineage	https://openalex.org/I4210165410
authorships[0].institutions[0].country_code	IT
authorships[0].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[0].institutions[1].id	https://openalex.org/I108290504
authorships[0].institutions[1].ror	https://ror.org/03ad39j10
authorships[0].institutions[1].type	education
authorships[0].institutions[1].lineage	https://openalex.org/I108290504
authorships[0].institutions[1].country_code	IT
authorships[0].institutions[1].display_name	University of Pisa
authorships[0].author_position	first
authorships[0].raw_author_name	G. Vetere
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[1].author.id	https://openalex.org/A5005516545
authorships[1].author.orcid	https://orcid.org/0000-0002-1036-5869
authorships[1].author.display_name	Marco Maria Germani
authorships[1].countries	IT
authorships[1].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[1].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[1].institutions[0].id	https://openalex.org/I4210165410
authorships[1].institutions[0].ror	https://ror.org/05xrcj819
authorships[1].institutions[0].type	healthcare
authorships[1].institutions[0].lineage	https://openalex.org/I4210165410
authorships[1].institutions[0].country_code	IT
authorships[1].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[1].institutions[1].id	https://openalex.org/I108290504
authorships[1].institutions[1].ror	https://ror.org/03ad39j10
authorships[1].institutions[1].type	education
authorships[1].institutions[1].lineage	https://openalex.org/I108290504
authorships[1].institutions[1].country_code	IT
authorships[1].institutions[1].display_name	University of Pisa
authorships[1].author_position	middle
authorships[1].raw_author_name	M. Germani
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[2].author.id	https://openalex.org/A5074681974
authorships[2].author.orcid	https://orcid.org/0000-0002-5647-0525
authorships[2].author.display_name	Maria Bensi
authorships[2].countries	IT
authorships[2].affiliations[0].institution_ids	https://openalex.org/I103320735, https://openalex.org/I2802557943
authorships[2].affiliations[0].raw_affiliation_string	Comprehensive Cancer Center, Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
authorships[2].institutions[0].id	https://openalex.org/I2802557943
authorships[2].institutions[0].ror	https://ror.org/00rg70c39
authorships[2].institutions[0].type	healthcare
authorships[2].institutions[0].lineage	https://openalex.org/I2802557943
authorships[2].institutions[0].country_code	IT
authorships[2].institutions[0].display_name	Agostino Gemelli University Polyclinic
authorships[2].institutions[1].id	https://openalex.org/I103320735
authorships[2].institutions[1].ror	https://ror.org/03h7r5v07
authorships[2].institutions[1].type	education
authorships[2].institutions[1].lineage	https://openalex.org/I103320735
authorships[2].institutions[1].country_code	IT
authorships[2].institutions[1].display_name	Università Cattolica del Sacro Cuore
authorships[2].author_position	middle
authorships[2].raw_author_name	M. Bensi
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Comprehensive Cancer Center, Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
authorships[3].author.id	https://openalex.org/A5080776095
authorships[3].author.orcid	https://orcid.org/0000-0001-6881-3188
authorships[3].author.display_name	Carlotta Antoniotti
authorships[3].countries	IT
authorships[3].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[3].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[3].institutions[0].id	https://openalex.org/I4210165410
authorships[3].institutions[0].ror	https://ror.org/05xrcj819
authorships[3].institutions[0].type	healthcare
authorships[3].institutions[0].lineage	https://openalex.org/I4210165410
authorships[3].institutions[0].country_code	IT
authorships[3].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[3].institutions[1].id	https://openalex.org/I108290504
authorships[3].institutions[1].ror	https://ror.org/03ad39j10
authorships[3].institutions[1].type	education
authorships[3].institutions[1].lineage	https://openalex.org/I108290504
authorships[3].institutions[1].country_code	IT
authorships[3].institutions[1].display_name	University of Pisa
authorships[3].author_position	middle
authorships[3].raw_author_name	C. Antoniotti
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[4].author.id	https://openalex.org/A5051613962
authorships[4].author.orcid	https://orcid.org/0000-0002-7593-8138
authorships[4].author.display_name	Sara Lonardi
authorships[4].countries	IT
authorships[4].affiliations[0].institution_ids	https://openalex.org/I4210109345, https://openalex.org/I4210153126
authorships[4].affiliations[0].raw_affiliation_string	Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy
authorships[4].institutions[0].id	https://openalex.org/I4210153126
authorships[4].institutions[0].ror	https://ror.org/04tfzc498
authorships[4].institutions[0].type	healthcare
authorships[4].institutions[0].lineage	https://openalex.org/I4210153126
authorships[4].institutions[0].country_code	IT
authorships[4].institutions[0].display_name	Istituti di Ricovero e Cura a Carattere Scientifico
authorships[4].institutions[1].id	https://openalex.org/I4210109345
authorships[4].institutions[1].ror	https://ror.org/01xcjmy57
authorships[4].institutions[1].type	healthcare
authorships[4].institutions[1].lineage	https://openalex.org/I4210109345, https://openalex.org/I4210153126
authorships[4].institutions[1].country_code	IT
authorships[4].institutions[1].display_name	Istituto Oncologico Veneto
authorships[4].author_position	middle
authorships[4].raw_author_name	S. Lonardi
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy
authorships[5].author.id	https://openalex.org/A5087670194
authorships[5].author.orcid	https://orcid.org/0000-0002-7099-240X
authorships[5].author.display_name	Alessandro Passardi
authorships[5].countries	IT
authorships[5].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[5].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[5].institutions[0].id	https://openalex.org/I4210165410
authorships[5].institutions[0].ror	https://ror.org/05xrcj819
authorships[5].institutions[0].type	healthcare
authorships[5].institutions[0].lineage	https://openalex.org/I4210165410
authorships[5].institutions[0].country_code	IT
authorships[5].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[5].institutions[1].id	https://openalex.org/I108290504
authorships[5].institutions[1].ror	https://ror.org/03ad39j10
authorships[5].institutions[1].type	education
authorships[5].institutions[1].lineage	https://openalex.org/I108290504
authorships[5].institutions[1].country_code	IT
authorships[5].institutions[1].display_name	University of Pisa
authorships[5].author_position	middle
authorships[5].raw_author_name	A. Passardi
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[6].author.id	https://openalex.org/A5020873515
authorships[6].author.orcid	https://orcid.org/0009-0001-1820-4402
authorships[6].author.display_name	Filippo Ghelardi
authorships[6].countries	IT
authorships[6].affiliations[0].institution_ids	https://openalex.org/I4210156707
authorships[6].affiliations[0].raw_affiliation_string	Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
authorships[6].institutions[0].id	https://openalex.org/I4210156707
authorships[6].institutions[0].ror	https://ror.org/05dwj7825
authorships[6].institutions[0].type	healthcare
authorships[6].institutions[0].lineage	https://openalex.org/I4210153126, https://openalex.org/I4210156707
authorships[6].institutions[0].country_code	IT
authorships[6].institutions[0].display_name	Fondazione IRCCS Istituto Nazionale dei Tumori
authorships[6].author_position	middle
authorships[6].raw_author_name	F. Ghelardi
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
authorships[7].author.id	https://openalex.org/A5016773277
authorships[7].author.orcid	https://orcid.org/0000-0001-6856-2593
authorships[7].author.display_name	Maria Alessandra Calegari
authorships[7].countries	IT
authorships[7].affiliations[0].institution_ids	https://openalex.org/I103320735, https://openalex.org/I2802557943
authorships[7].affiliations[0].raw_affiliation_string	Comprehensive Cancer Center, Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
authorships[7].institutions[0].id	https://openalex.org/I2802557943
authorships[7].institutions[0].ror	https://ror.org/00rg70c39
authorships[7].institutions[0].type	healthcare
authorships[7].institutions[0].lineage	https://openalex.org/I2802557943
authorships[7].institutions[0].country_code	IT
authorships[7].institutions[0].display_name	Agostino Gemelli University Polyclinic
authorships[7].institutions[1].id	https://openalex.org/I103320735
authorships[7].institutions[1].ror	https://ror.org/03h7r5v07
authorships[7].institutions[1].type	education
authorships[7].institutions[1].lineage	https://openalex.org/I103320735
authorships[7].institutions[1].country_code	IT
authorships[7].institutions[1].display_name	Università Cattolica del Sacro Cuore
authorships[7].author_position	middle
authorships[7].raw_author_name	M. Calegari
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Comprehensive Cancer Center, Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
authorships[8].author.id	https://openalex.org/A5066696741
authorships[8].author.orcid	https://orcid.org/0000-0002-9739-408X
authorships[8].author.display_name	Beatrice Borelli
authorships[8].countries	IT
authorships[8].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[8].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[8].institutions[0].id	https://openalex.org/I4210165410
authorships[8].institutions[0].ror	https://ror.org/05xrcj819
authorships[8].institutions[0].type	healthcare
authorships[8].institutions[0].lineage	https://openalex.org/I4210165410
authorships[8].institutions[0].country_code	IT
authorships[8].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[8].institutions[1].id	https://openalex.org/I108290504
authorships[8].institutions[1].ror	https://ror.org/03ad39j10
authorships[8].institutions[1].type	education
authorships[8].institutions[1].lineage	https://openalex.org/I108290504
authorships[8].institutions[1].country_code	IT
authorships[8].institutions[1].display_name	University of Pisa
authorships[8].author_position	middle
authorships[8].raw_author_name	B. Borelli
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[9].author.id	https://openalex.org/A5113239315
authorships[9].author.orcid
authorships[9].author.display_name	S. Santucci
authorships[9].countries	IT
authorships[9].affiliations[0].institution_ids	https://openalex.org/I4210092828
authorships[9].affiliations[0].raw_affiliation_string	Oncology Unit, Santa Maria delle Croci Hospital, Ravenna, Italy
authorships[9].institutions[0].id	https://openalex.org/I4210092828
authorships[9].institutions[0].ror	https://ror.org/00g6kte47
authorships[9].institutions[0].type	healthcare
authorships[9].institutions[0].lineage	https://openalex.org/I4210092828, https://openalex.org/I4210107542
authorships[9].institutions[0].country_code	IT
authorships[9].institutions[0].display_name	Ospedale "Santa Maria delle Croci" di Ravenna
authorships[9].author_position	middle
authorships[9].raw_author_name	S. Santucci
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	Oncology Unit, Santa Maria delle Croci Hospital, Ravenna, Italy
authorships[10].author.id	https://openalex.org/A5013247333
authorships[10].author.orcid	https://orcid.org/0000-0001-8428-0721
authorships[10].author.display_name	Rossana Intini
authorships[10].countries	IT
authorships[10].affiliations[0].institution_ids	https://openalex.org/I4210109345
authorships[10].affiliations[0].raw_affiliation_string	Medical Oncology 1, Department of Oncology, Veneto Institute of Oncology IOV– IRCCS, Padua, Italy
authorships[10].institutions[0].id	https://openalex.org/I4210109345
authorships[10].institutions[0].ror	https://ror.org/01xcjmy57
authorships[10].institutions[0].type	healthcare
authorships[10].institutions[0].lineage	https://openalex.org/I4210109345, https://openalex.org/I4210153126
authorships[10].institutions[0].country_code	IT
authorships[10].institutions[0].display_name	Istituto Oncologico Veneto
authorships[10].author_position	middle
authorships[10].raw_author_name	R. Intini
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	Medical Oncology 1, Department of Oncology, Veneto Institute of Oncology IOV– IRCCS, Padua, Italy
authorships[11].author.id	https://openalex.org/A5083510937
authorships[11].author.orcid	https://orcid.org/0009-0005-0210-6241
authorships[11].author.display_name	Eleonora Cristarella
authorships[11].countries	IT
authorships[11].affiliations[0].institution_ids	https://openalex.org/I4210156707
authorships[11].affiliations[0].raw_affiliation_string	Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
authorships[11].institutions[0].id	https://openalex.org/I4210156707
authorships[11].institutions[0].ror	https://ror.org/05dwj7825
authorships[11].institutions[0].type	healthcare
authorships[11].institutions[0].lineage	https://openalex.org/I4210153126, https://openalex.org/I4210156707
authorships[11].institutions[0].country_code	IT
authorships[11].institutions[0].display_name	Fondazione IRCCS Istituto Nazionale dei Tumori
authorships[11].author_position	middle
authorships[11].raw_author_name	E. Cristarella
authorships[11].is_corresponding	False
authorships[11].raw_affiliation_strings	Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
authorships[12].author.id	https://openalex.org/A5033536074
authorships[12].author.orcid	https://orcid.org/0000-0003-3600-0232
authorships[12].author.display_name	Mara Persano
authorships[12].countries	IT
authorships[12].affiliations[0].institution_ids	https://openalex.org/I172446870
authorships[12].affiliations[0].raw_affiliation_string	Medical Oncology Department, University Hospital, University of Cagliari Cittadella Universitaria di Monserrato, Cagliari, Italy
authorships[12].institutions[0].id	https://openalex.org/I172446870
authorships[12].institutions[0].ror	https://ror.org/003109y17
authorships[12].institutions[0].type	education
authorships[12].institutions[0].lineage	https://openalex.org/I172446870
authorships[12].institutions[0].country_code	IT
authorships[12].institutions[0].display_name	University of Cagliari
authorships[12].author_position	middle
authorships[12].raw_author_name	M. Persano
authorships[12].is_corresponding	False
authorships[12].raw_affiliation_strings	Medical Oncology Department, University Hospital, University of Cagliari Cittadella Universitaria di Monserrato, Cagliari, Italy
authorships[13].author.id	https://openalex.org/A5033552387
authorships[13].author.orcid	https://orcid.org/0000-0002-2492-4043
authorships[13].author.display_name	Alberto Puccini
authorships[13].countries	IT
authorships[13].affiliations[0].institution_ids	https://openalex.org/I4210146472
authorships[13].affiliations[0].raw_affiliation_string	Medical Oncology Unit 1, IRCCS Ospedale San Martino, Genoa, Italy
authorships[13].institutions[0].id	https://openalex.org/I4210146472
authorships[13].institutions[0].ror	https://ror.org/04d7es448
authorships[13].institutions[0].type	healthcare
authorships[13].institutions[0].lineage	https://openalex.org/I4210146472, https://openalex.org/I4210153126
authorships[13].institutions[0].country_code	IT
authorships[13].institutions[0].display_name	Ospedale Policlinico San Martino
authorships[13].author_position	middle
authorships[13].raw_author_name	A. Puccini
authorships[13].is_corresponding	False
authorships[13].raw_affiliation_strings	Medical Oncology Unit 1, IRCCS Ospedale San Martino, Genoa, Italy
authorships[14].author.id	https://openalex.org/A5069705709
authorships[14].author.orcid
authorships[14].author.display_name	Daniele Lavacchi
authorships[14].countries	IT
authorships[14].affiliations[0].institution_ids	https://openalex.org/I1339471597
authorships[14].affiliations[0].raw_affiliation_string	Department of Biomedical Sciences, Humanitas University, Milan, Italy
authorships[14].affiliations[1].institution_ids	https://openalex.org/I4210163047
authorships[14].affiliations[1].raw_affiliation_string	Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Humanitas Cancer Center, Milan, Italy
authorships[14].institutions[0].id	https://openalex.org/I1339471597
authorships[14].institutions[0].ror	https://ror.org/020dggs04
authorships[14].institutions[0].type	education
authorships[14].institutions[0].lineage	https://openalex.org/I1339471597
authorships[14].institutions[0].country_code	IT
authorships[14].institutions[0].display_name	Humanitas University
authorships[14].institutions[1].id	https://openalex.org/I4210163047
authorships[14].institutions[1].ror	https://ror.org/05d538656
authorships[14].institutions[1].type	healthcare
authorships[14].institutions[1].lineage	https://openalex.org/I4210153126, https://openalex.org/I4210163047
authorships[14].institutions[1].country_code	IT
authorships[14].institutions[1].display_name	IRCCS Humanitas Research Hospital
authorships[14].author_position	middle
authorships[14].raw_author_name	D. Lavacchi
authorships[14].is_corresponding	False
authorships[14].raw_affiliation_strings	Department of Biomedical Sciences, Humanitas University, Milan, Italy, Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Humanitas Cancer Center, Milan, Italy
authorships[15].author.id	https://openalex.org/A5007481827
authorships[15].author.orcid	https://orcid.org/0000-0002-3280-2898
authorships[15].author.display_name	Leonardo Noto
authorships[15].affiliations[0].raw_affiliation_string	Medical Oncology, University Hospital Policlinico G. Rodolico-S. Marco, Catania, Italy
authorships[15].author_position	middle
authorships[15].raw_author_name	L. Noto
authorships[15].is_corresponding	False
authorships[15].raw_affiliation_strings	Medical Oncology, University Hospital Policlinico G. Rodolico-S. Marco, Catania, Italy
authorships[16].author.id	https://openalex.org/A5017771299
authorships[16].author.orcid	https://orcid.org/0000-0001-8981-4155
authorships[16].author.display_name	Clizia Zichi
authorships[16].countries	IT
authorships[16].affiliations[0].institution_ids	https://openalex.org/I4210129188
authorships[16].affiliations[0].raw_affiliation_string	Division of Medical Oncology, Ordine Mauriziano Hospital, Turin, Italy
authorships[16].institutions[0].id	https://openalex.org/I4210129188
authorships[16].institutions[0].ror	https://ror.org/03efxpx82
authorships[16].institutions[0].type	healthcare
authorships[16].institutions[0].lineage	https://openalex.org/I4210129188
authorships[16].institutions[0].country_code	IT
authorships[16].institutions[0].display_name	A. O. Ordine Mauriziano di Torino
authorships[16].author_position	middle
authorships[16].raw_author_name	C. Zichi
authorships[16].is_corresponding	False
authorships[16].raw_affiliation_strings	Division of Medical Oncology, Ordine Mauriziano Hospital, Turin, Italy
authorships[17].author.id	https://openalex.org/A5015406288
authorships[17].author.orcid	https://orcid.org/0000-0001-7344-0590
authorships[17].author.display_name	Riccardo Giampieri
authorships[17].countries	IT
authorships[17].affiliations[0].institution_ids	https://openalex.org/I122534668
authorships[17].affiliations[0].raw_affiliation_string	Clinica Oncologica - Dipartimento Scienze Cliniche e Molecolari - Università Politecnica delle Marche & Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
authorships[17].institutions[0].id	https://openalex.org/I122534668
authorships[17].institutions[0].ror	https://ror.org/00x69rs40
authorships[17].institutions[0].type	education
authorships[17].institutions[0].lineage	https://openalex.org/I122534668
authorships[17].institutions[0].country_code	IT
authorships[17].institutions[0].display_name	Marche Polytechnic University
authorships[17].author_position	middle
authorships[17].raw_author_name	R. Giampieri
authorships[17].is_corresponding	False
authorships[17].raw_affiliation_strings	Clinica Oncologica - Dipartimento Scienze Cliniche e Molecolari - Università Politecnica delle Marche & Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
authorships[18].author.id	https://openalex.org/A5000225240
authorships[18].author.orcid	https://orcid.org/0000-0002-5579-7454
authorships[18].author.display_name	Massimiliano Salati
authorships[18].countries	US
authorships[18].affiliations[0].institution_ids	https://openalex.org/I166722992
authorships[18].affiliations[0].raw_affiliation_string	University of Massachusetts Medical School, Worcester, United States
authorships[18].institutions[0].id	https://openalex.org/I166722992
authorships[18].institutions[0].ror	https://ror.org/0464eyp60
authorships[18].institutions[0].type	education
authorships[18].institutions[0].lineage	https://openalex.org/I166722992
authorships[18].institutions[0].country_code	US
authorships[18].institutions[0].display_name	University of Massachusetts Chan Medical School
authorships[18].author_position	middle
authorships[18].raw_author_name	M. Salati
authorships[18].is_corresponding	False
authorships[18].raw_affiliation_strings	University of Massachusetts Medical School, Worcester, United States
authorships[19].author.id	https://openalex.org/A5081985776
authorships[19].author.orcid	https://orcid.org/0000-0002-0520-4841
authorships[19].author.display_name	Chiara Cremolini
authorships[19].countries	IT
authorships[19].affiliations[0].institution_ids	https://openalex.org/I108290504, https://openalex.org/I4210165410
authorships[19].affiliations[0].raw_affiliation_string	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
authorships[19].institutions[0].id	https://openalex.org/I4210165410
authorships[19].institutions[0].ror	https://ror.org/05xrcj819
authorships[19].institutions[0].type	healthcare
authorships[19].institutions[0].lineage	https://openalex.org/I4210165410
authorships[19].institutions[0].country_code	IT
authorships[19].institutions[0].display_name	Azienda Ospedaliera Universitaria Pisana
authorships[19].institutions[1].id	https://openalex.org/I108290504
authorships[19].institutions[1].ror	https://ror.org/03ad39j10
authorships[19].institutions[1].type	education
authorships[19].institutions[1].lineage	https://openalex.org/I108290504
authorships[19].institutions[1].country_code	IT
authorships[19].institutions[1].display_name	University of Pisa
authorships[19].author_position	last
authorships[19].raw_author_name	C. Cremolini
authorships[19].is_corresponding	False
authorships[19].raw_affiliation_strings	Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa and Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
has_content.pdf	True
has_content.grobid_xml	True
is_paratext	False
open_access.is_oa	True
open_access.oa_url	http://www.annalsofoncology.org/article/S0923753423002880/pdf
open_access.oa_status	bronze
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	P-90 Prognostic impact of depth of response (DpR) and early tumour shrinkage (ETS) in patients (pts) with BRAFV600E mutated (mut) metastatic colorectal cancer (mCRC) receiving targeted therapy (TT) as second-line treatment
has_fulltext	True
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T11067
primary_topic.field.id	https://openalex.org/fields/27
primary_topic.field.display_name	Medicine
primary_topic.score	0.9959999918937683
primary_topic.domain.id	https://openalex.org/domains/4
primary_topic.domain.display_name	Health Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2730
primary_topic.subfield.display_name	Oncology
primary_topic.display_name	Colorectal Cancer Treatments and Studies
related_works	https://openalex.org/W1705932695, https://openalex.org/W90289501, https://openalex.org/W2040366372, https://openalex.org/W2043390473, https://openalex.org/W2336199709, https://openalex.org/W2362126043, https://openalex.org/W2352791572, https://openalex.org/W2097952607, https://openalex.org/W3037752552, https://openalex.org/W2597414803
cited_by_count	3
counts_by_year[0].year	2023
counts_by_year[0].cited_by_count	3
locations_count	1
best_oa_location.id	doi:10.1016/j.annonc.2023.04.146
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S41454044
best_oa_location.source.issn	0923-7534, 1569-8041
best_oa_location.source.type	journal
best_oa_location.source.is_oa	False
best_oa_location.source.issn_l	0923-7534
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	False
best_oa_location.source.display_name	Annals of Oncology
best_oa_location.source.host_organization	https://openalex.org/P4310320990
best_oa_location.source.host_organization_name	Elsevier BV
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310320990
best_oa_location.license	publisher-specific-oa
best_oa_location.pdf_url	http://www.annalsofoncology.org/article/S0923753423002880/pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id	https://openalex.org/licenses/publisher-specific-oa
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Annals of Oncology
best_oa_location.landing_page_url	https://doi.org/10.1016/j.annonc.2023.04.146
primary_location.id	doi:10.1016/j.annonc.2023.04.146
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S41454044
primary_location.source.issn	0923-7534, 1569-8041
primary_location.source.type	journal
primary_location.source.is_oa	False
primary_location.source.issn_l	0923-7534
primary_location.source.is_core	True
primary_location.source.is_in_doaj	False
primary_location.source.display_name	Annals of Oncology
primary_location.source.host_organization	https://openalex.org/P4310320990
primary_location.source.host_organization_name	Elsevier BV
primary_location.source.host_organization_lineage	https://openalex.org/P4310320990
primary_location.license	publisher-specific-oa
primary_location.pdf_url	http://www.annalsofoncology.org/article/S0923753423002880/pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id	https://openalex.org/licenses/publisher-specific-oa
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Annals of Oncology
primary_location.landing_page_url	https://doi.org/10.1016/j.annonc.2023.04.146
publication_date	2023-06-01
publication_year	2023
referenced_works	https://openalex.org/W4382799245
referenced_works_count	1
abstract_inverted_index
cited_by_percentile_year.max	97
cited_by_percentile_year.min	96
countries_distinct_count	2
institutions_distinct_count	20
sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.800000011920929
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.78600185
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False