P.035 Using deferred consent in emergency research: an evaluation of two prospective CT-perfusion studies Article Swipe

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Susan Alcock , Bronagh Blackwood , Marco Ayroso , Jai Shankar ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1017/cjn.2025.10216

Background: Informed consent is not always possible in emergency research particularly during life threatening situations. Deferral of consent is an acceptable method in consenting patients; however, it is underutilized. We aim to share our experience with deferred consent. Methods: Participants in two prospective studies underwent a CT-Perfusion scan (intervention) at the time of first hospital imaging, in order not to impact clinical treatment. Deferred consent was then obtained. The primary outcome was the rate of deferred consent. The number of days to obtain consent, refusal rate, and waiver of consent rate was also reported. Results: A total of 291 patients (200 severe traumatic brain injury [TBI] and 91 out-of-hospital cardiac arrest) were enrolled between the two emergency CT-perfusion studies. Some (34/291[11.9%]) could not be reached; waiver of consent was granted by our ethics board. Deferred consent was obtained in 252/291(86.6%). The majority were consented by the partner/spouse (25.2%) and most consents took place within 7-days (76.0%) of enrollment. Five (1.7%) refused consent. Deferred consent rates were higher in the cardiac arrest population (97.8%) compared to the severe TBI population (83.7%). Conclusions: Deferred consent is an acceptable method of obtaining consent in emergency research when the intervention risk is low.

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Perfusion Medicine Informed consent Emergency medicine Medical physics Nuclear medicine Medical emergency Radiology Pathology Alternative medicine

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Type: article
Language: en
Landing Page: https://doi.org/10.1017/cjn.2025.10216
PDF: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/BF32EA3744C704B2ED06949250012715/S0317167125102163a.pdf/div-class-title-p-035-using-deferred-consent-in-emergency-research-an-evaluation-of-two-prospective-ct-perfusion-studies-div.pdf
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Related Works: 10
OpenAlex ID: https://openalex.org/W4412166620

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DOI: https://doi.org/10.1017/cjn.2025.10216

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Title: P.035 Using deferred consent in emergency research: an evaluation of two prospective CT-perfusion studies

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Language: en

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Publication year: 2025

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Publication date: 2025-06-01

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Authors: Susan Alcock, Bronagh Blackwood, Marco Ayroso, Jai Shankar

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Landing page: https://doi.org/10.1017/cjn.2025.10216

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PDF URL: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/BF32EA3744C704B2ED06949250012715/S0317167125102163a.pdf/div-class-title-p-035-using-deferred-consent-in-emergency-research-an-evaluation-of-two-prospective-ct-perfusion-studies-div.pdf

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Concepts: Perfusion, Medicine, Informed consent, Emergency medicine, Medical physics, Nuclear medicine, Medical emergency, Radiology, Pathology, Alternative medicine

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