P1173 Results of salvage ileal-pouch-anal anastomosis surgery in Ulcerative Colitis patients with restorative proctocolectomy Article Swipe
C. Altieri
,
E P Emma
,
Cristina Luceri
,
Lorenzo Vacca
,
Marta Cricchio
,
Federico Perna
,
Ferdinando Ficari
,
Stefano Scaringi
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1093/ecco-jcc/jjae190.1347
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1093/ecco-jcc/jjae190.1347
Background Restorative proctocolectomy (PCT) with ileal-pouch-anal anastomosis (IPAA) is the surgical treatment in medically refractory ulcerative colitis (UC). Short and long-term complications are septic (abscess/fistula), inflammatory (pouchitis/cuffitis) or functional (stenosis/incontinence). Salvage surgery can be performed in order to avoid permanent end ileostomy, but literature is scarce. The aim of study is to evaluate the outcomes of IPAA salvage surgery.The primary endpoint was to analyze the percentage of patients who underwent an end ileostomy.The secondary one was to analyze risk factors for complications that lead to an end ileostomy. Methods Patients consecutively operated for PCT and IPAA between 1992 and 2020 were retrospectively collected, including demographics, first diagnosis, technical details of the primary IPAA, type of reconstructions and post-operative outcomes. The group that developed complications was analyzed, describing the outcome of different surgical managements regarding each subgroup of complication. Statistical analysis was performed with a dedicated software. Results A total of 225 patients were reported in the observational period:169 were free from complications and 69 (30.6%) underwent pouch salvage surgery; 17 (10.9%) of them had a permanent end ileostomy, while on 52 patients pouch salvage was performed with a good rate of success (89.1%).Among 52.9% of the patients undergoing permanent end ileostomy, an inflammatory complication occurred. Fistulas (40.5%) were the most frequent and had the best outcome. Pouchitis was present in 9 patients, but 5 of them had a permanent end ileostomy performed.The risk of end ileostomy was higher in male and in patients undergoing numerous surgeries, whilst it is lower in young patients. Conclusion IPAA salvage surgery is safe and provides good results with a high rate of success when performed in a referral center. It has good outcomes concerning septic complications, while it is less effective in treating inflammatory complications.
Related Topics
Concepts
Medicine
Proctocolectomy
Ulcerative colitis
Anastomosis
Pouch
Surgery
General surgery
Internal medicine
Disease
Metadata
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- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/ecco-jcc/jjae190.1347
- OA Status
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4406699253Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/ecco-jcc/jjae190.1347Digital Object Identifier
- Title
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P1173 Results of salvage ileal-pouch-anal anastomosis surgery in Ulcerative Colitis patients with restorative proctocolectomyWork title
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articleOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-01-01Full publication date if available
- Authors
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C. Altieri, E P Emma, Cristina Luceri, Lorenzo Vacca, Marta Cricchio, Federico Perna, Ferdinando Ficari, Stefano ScaringiList of authors in order
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https://doi.org/10.1093/ecco-jcc/jjae190.1347Publisher landing page
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://hdl.handle.net/2158/1423274Direct OA link when available
- Concepts
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Medicine, Proctocolectomy, Ulcerative colitis, Anastomosis, Pouch, Surgery, General surgery, Internal medicine, DiseaseTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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