Papel de la inmunidad humoral y celular en el condicionamiento evolutivo de la hepatitis B Article Swipe

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YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.15581/021.23.5371

Se efectúa un análisis inmunocelular e inmunohumoral un total de 75 individuos antígeno Australia positivos, con diversas formas evolutivas (hepatitis agudas, hepatitis crónicas agresivas, hepatitis crónicas persistentes y portadores asintomáticos), comparando los resultados entre los distintos grupos y los obtenidos en 20 personas sanas utilizadas como control. En primer lugar, se estudia la respuesta inmunitaria humoral mediante la determinación de las tres inmunoglobulinas principales en cada grupo. Ulteriormente, se analiza la respuesta inmunocelular cuantitativa, mediante el recuento porcentual de rosetas E espontáneas con eritrocitos de carnero. Previa concentración y purificación del antígeno Australia, y mediante el test del factor de inhibición de la migración de leucocitos humanos periféricos (MIF) se determina la respuesta inmunitaria celular cualitativa y especifica frente al propio antígeno Australia. Finalmente se interrelacionan estadísticamente los resultados de ambas vertientes inmunitarias en cada grupo, así como otros factores no inmunológicos, tratando de dilucidar los mecanismos patogenéticos responsables de las distintas formas evolutivas de hepatitis B.

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Molecular biology Hepatitis B Biology Medicine Virology

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Type: article
Language: es
Landing Page: https://doi.org/10.15581/021.23.5371
PDF: https://revistas.unav.edu/index.php/revista-de-medicina/article/download/5371/4612
OA Status: hybrid
Cited By: 1
References: 15
Related Works: 10
OpenAlex ID: https://openalex.org/W4312545043

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OpenAlex ID: https://openalex.org/W4312545043

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DOI: https://doi.org/10.15581/021.23.5371

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Title: Papel de la inmunidad humoral y celular en el condicionamiento evolutivo de la hepatitis B

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Type: article

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Language: es

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Publication year: 2016

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Publication date: 2016-05-18

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Authors: A. Cabarcos Cazón, Merce Miranda

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Landing page: https://doi.org/10.15581/021.23.5371

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PDF URL: https://revistas.unav.edu/index.php/revista-de-medicina/article/download/5371/4612

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OA status: hybrid

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OA URL: https://revistas.unav.edu/index.php/revista-de-medicina/article/download/5371/4612

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Concepts: Molecular biology, Hepatitis B, Biology, Medicine, Virology

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Cited by: 1

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Citations by year (recent): 2016: 1

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References (count): 15

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