Particle interactions and their effect on magnetic particle imaging and spectroscopy Article Swipe
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1101/2021.10.29.466424
Tracer and thus signal stability is crucial for an accurate diagnosis via magnetic particle imaging (MPI). However, MPI-tracer nanoparticles frequently agglomerate during their in vivo applications leading to particle interactions. Here, we investigate the influence of such magnetic coupling phenomena on the MPI signal. We prepared and characterized Zn 0.4 Fe 2.6 O 4 nanoparticles and controlled their interparticle distance by variying SiO 2 coating thickness. The silica shell affected the magnetic properties indicating stronger particle interactions for a smaller interparticle distance. The SiO 2 -coated Zn 0.4 Fe 2.6 O 4 outperformed the bare sample in magnetic particle spectroscopy (MPS) in terms of signal/noise, however, the shell thickness itself only weakly influenced the MPS signal. To investigate the importance of magnetic coupling effects in more detail, we benchmarked the MPS signal of the bare and SiO 2 -coated Zn-ferrites against commercially available PVP-coated Fe 3 O 4 nanoparticles in water and PBS. PBS is known to destabilize nanoparticles mimicking an agglomeration in vivo. The bare and coated Zn-ferrites showed excellent signal stability, despite their agglomeration in PBS. We attribute this to their aggregated morphology formed during their flame-synthesis. On the other hand, the MPS signal of commercial PVP-coated Fe 3 O 4 strongly decreased in PBS compared to water, indicating strongly changed particle interactions. The relevance of this effect was further investigated in a mammalian cell model. For PVP-coated Fe 3 O 4 , we could detect a strong discrepancy between the particle concentration obtained from the MPS signal and the actual concentration determined via ICP-MS. The same trend was observed during their MPI analysis; while SiO 2 -coated Zn-ferrites could be precisely located in water and PBS, PVP-coated Fe 3 O 4 could not be detected in PBS at all. This drastically limits the sensitivity and also general applicability of MPI using such standard commercial tracers and highlights the advantages of our flame-made Zn-ferrites concerning signal stability and ultimately diagnostic accuracy.
Related Topics
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2021.10.29.466424
- https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdf
- OA Status
- green
- References
- 32
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4234900825
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4234900825Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1101/2021.10.29.466424Digital Object Identifier
- Title
-
Particle interactions and their effect on magnetic particle imaging and spectroscopyWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-11-01Full publication date if available
- Authors
-
Lorena Moor, Subas Scheibler, Lukas R. H. Gerken, Konrad Scheffler, Florian Thieben, Tobias Knopp, Inge K. Herrmann, Fabian H. L. StarsichList of authors in order
- Landing page
-
https://doi.org/10.1101/2021.10.29.466424Publisher landing page
- PDF URL
-
https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdfDirect OA link when available
- Concepts
-
Magnetic particle imaging, Particle (ecology), Nanoparticle, Agglomerate, Materials science, Economies of agglomeration, SIGNAL (programming language), Particle size, Magnetic nanoparticles, Spectroscopy, Coating, Chemical engineering, Nanotechnology, Analytical Chemistry (journal), Chemical physics, Chemistry, Composite material, Chromatography, Geology, Engineering, Programming language, Oceanography, Computer science, Quantum mechanics, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
32Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4234900825 |
|---|---|
| doi | https://doi.org/10.1101/2021.10.29.466424 |
| ids.doi | https://doi.org/10.1101/2021.10.29.466424 |
| ids.openalex | https://openalex.org/W4234900825 |
| fwci | 0.0 |
| type | preprint |
| title | Particle interactions and their effect on magnetic particle imaging and spectroscopy |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T12405 |
| topics[0].field.id | https://openalex.org/fields/22 |
| topics[0].field.display_name | Engineering |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2204 |
| topics[0].subfield.display_name | Biomedical Engineering |
| topics[0].display_name | Characterization and Applications of Magnetic Nanoparticles |
| topics[1].id | https://openalex.org/T11786 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9937999844551086 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Geomagnetism and Paleomagnetism Studies |
| topics[2].id | https://openalex.org/T11401 |
| topics[2].field.id | https://openalex.org/fields/23 |
| topics[2].field.display_name | Environmental Science |
| topics[2].score | 0.9927999973297119 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2312 |
| topics[2].subfield.display_name | Water Science and Technology |
| topics[2].display_name | Minerals Flotation and Separation Techniques |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C140722275 |
| concepts[0].level | 4 |
| concepts[0].score | 0.7740572690963745 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1884331 |
| concepts[0].display_name | Magnetic particle imaging |
| concepts[1].id | https://openalex.org/C2778517922 |
| concepts[1].level | 2 |
| concepts[1].score | 0.692579448223114 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q7140482 |
| concepts[1].display_name | Particle (ecology) |
| concepts[2].id | https://openalex.org/C155672457 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6828354597091675 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q61231 |
| concepts[2].display_name | Nanoparticle |
| concepts[3].id | https://openalex.org/C129955480 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6642279028892517 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q1257738 |
| concepts[3].display_name | Agglomerate |
| concepts[4].id | https://openalex.org/C192562407 |
| concepts[4].level | 0 |
| concepts[4].score | 0.6052694320678711 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q228736 |
| concepts[4].display_name | Materials science |
| concepts[5].id | https://openalex.org/C131850264 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5445123910903931 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q383056 |
| concepts[5].display_name | Economies of agglomeration |
| concepts[6].id | https://openalex.org/C2779843651 |
| concepts[6].level | 2 |
| concepts[6].score | 0.49407294392585754 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q7390335 |
| concepts[6].display_name | SIGNAL (programming language) |
| concepts[7].id | https://openalex.org/C187530423 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4867079555988312 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7140503 |
| concepts[7].display_name | Particle size |
| concepts[8].id | https://openalex.org/C87023908 |
| concepts[8].level | 3 |
| concepts[8].score | 0.4814112186431885 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q3870166 |
| concepts[8].display_name | Magnetic nanoparticles |
| concepts[9].id | https://openalex.org/C32891209 |
| concepts[9].level | 2 |
| concepts[9].score | 0.4781675934791565 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q483666 |
| concepts[9].display_name | Spectroscopy |
| concepts[10].id | https://openalex.org/C2781448156 |
| concepts[10].level | 2 |
| concepts[10].score | 0.42415016889572144 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q1570182 |
| concepts[10].display_name | Coating |
| concepts[11].id | https://openalex.org/C42360764 |
| concepts[11].level | 1 |
| concepts[11].score | 0.3865189850330353 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q83588 |
| concepts[11].display_name | Chemical engineering |
| concepts[12].id | https://openalex.org/C171250308 |
| concepts[12].level | 1 |
| concepts[12].score | 0.38631004095077515 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q11468 |
| concepts[12].display_name | Nanotechnology |
| concepts[13].id | https://openalex.org/C113196181 |
| concepts[13].level | 2 |
| concepts[13].score | 0.3747815489768982 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q485223 |
| concepts[13].display_name | Analytical Chemistry (journal) |
| concepts[14].id | https://openalex.org/C159467904 |
| concepts[14].level | 1 |
| concepts[14].score | 0.36518269777297974 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q2001702 |
| concepts[14].display_name | Chemical physics |
| concepts[15].id | https://openalex.org/C185592680 |
| concepts[15].level | 0 |
| concepts[15].score | 0.25331443548202515 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[15].display_name | Chemistry |
| concepts[16].id | https://openalex.org/C159985019 |
| concepts[16].level | 1 |
| concepts[16].score | 0.12544390559196472 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q181790 |
| concepts[16].display_name | Composite material |
| concepts[17].id | https://openalex.org/C43617362 |
| concepts[17].level | 1 |
| concepts[17].score | 0.0714150071144104 |
| concepts[17].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[17].display_name | Chromatography |
| concepts[18].id | https://openalex.org/C127313418 |
| concepts[18].level | 0 |
| concepts[18].score | 0.0 |
| concepts[18].wikidata | https://www.wikidata.org/wiki/Q1069 |
| concepts[18].display_name | Geology |
| concepts[19].id | https://openalex.org/C127413603 |
| concepts[19].level | 0 |
| concepts[19].score | 0.0 |
| concepts[19].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[19].display_name | Engineering |
| concepts[20].id | https://openalex.org/C199360897 |
| concepts[20].level | 1 |
| concepts[20].score | 0.0 |
| concepts[20].wikidata | https://www.wikidata.org/wiki/Q9143 |
| concepts[20].display_name | Programming language |
| concepts[21].id | https://openalex.org/C111368507 |
| concepts[21].level | 1 |
| concepts[21].score | 0.0 |
| concepts[21].wikidata | https://www.wikidata.org/wiki/Q43518 |
| concepts[21].display_name | Oceanography |
| concepts[22].id | https://openalex.org/C41008148 |
| concepts[22].level | 0 |
| concepts[22].score | 0.0 |
| concepts[22].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[22].display_name | Computer science |
| concepts[23].id | https://openalex.org/C62520636 |
| concepts[23].level | 1 |
| concepts[23].score | 0.0 |
| concepts[23].wikidata | https://www.wikidata.org/wiki/Q944 |
| concepts[23].display_name | Quantum mechanics |
| concepts[24].id | https://openalex.org/C121332964 |
| concepts[24].level | 0 |
| concepts[24].score | 0.0 |
| concepts[24].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[24].display_name | Physics |
| keywords[0].id | https://openalex.org/keywords/magnetic-particle-imaging |
| keywords[0].score | 0.7740572690963745 |
| keywords[0].display_name | Magnetic particle imaging |
| keywords[1].id | https://openalex.org/keywords/particle |
| keywords[1].score | 0.692579448223114 |
| keywords[1].display_name | Particle (ecology) |
| keywords[2].id | https://openalex.org/keywords/nanoparticle |
| keywords[2].score | 0.6828354597091675 |
| keywords[2].display_name | Nanoparticle |
| keywords[3].id | https://openalex.org/keywords/agglomerate |
| keywords[3].score | 0.6642279028892517 |
| keywords[3].display_name | Agglomerate |
| keywords[4].id | https://openalex.org/keywords/materials-science |
| keywords[4].score | 0.6052694320678711 |
| keywords[4].display_name | Materials science |
| keywords[5].id | https://openalex.org/keywords/economies-of-agglomeration |
| keywords[5].score | 0.5445123910903931 |
| keywords[5].display_name | Economies of agglomeration |
| keywords[6].id | https://openalex.org/keywords/signal |
| keywords[6].score | 0.49407294392585754 |
| keywords[6].display_name | SIGNAL (programming language) |
| keywords[7].id | https://openalex.org/keywords/particle-size |
| keywords[7].score | 0.4867079555988312 |
| keywords[7].display_name | Particle size |
| keywords[8].id | https://openalex.org/keywords/magnetic-nanoparticles |
| keywords[8].score | 0.4814112186431885 |
| keywords[8].display_name | Magnetic nanoparticles |
| keywords[9].id | https://openalex.org/keywords/spectroscopy |
| keywords[9].score | 0.4781675934791565 |
| keywords[9].display_name | Spectroscopy |
| keywords[10].id | https://openalex.org/keywords/coating |
| keywords[10].score | 0.42415016889572144 |
| keywords[10].display_name | Coating |
| keywords[11].id | https://openalex.org/keywords/chemical-engineering |
| keywords[11].score | 0.3865189850330353 |
| keywords[11].display_name | Chemical engineering |
| keywords[12].id | https://openalex.org/keywords/nanotechnology |
| keywords[12].score | 0.38631004095077515 |
| keywords[12].display_name | Nanotechnology |
| keywords[13].id | https://openalex.org/keywords/analytical-chemistry |
| keywords[13].score | 0.3747815489768982 |
| keywords[13].display_name | Analytical Chemistry (journal) |
| keywords[14].id | https://openalex.org/keywords/chemical-physics |
| keywords[14].score | 0.36518269777297974 |
| keywords[14].display_name | Chemical physics |
| keywords[15].id | https://openalex.org/keywords/chemistry |
| keywords[15].score | 0.25331443548202515 |
| keywords[15].display_name | Chemistry |
| keywords[16].id | https://openalex.org/keywords/composite-material |
| keywords[16].score | 0.12544390559196472 |
| keywords[16].display_name | Composite material |
| keywords[17].id | https://openalex.org/keywords/chromatography |
| keywords[17].score | 0.0714150071144104 |
| keywords[17].display_name | Chromatography |
| language | en |
| locations[0].id | doi:10.1101/2021.10.29.466424 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4306402567 |
| locations[0].source.issn | |
| locations[0].source.type | repository |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | bioRxiv (Cold Spring Harbor Laboratory) |
| locations[0].source.host_organization | https://openalex.org/I2750212522 |
| locations[0].source.host_organization_name | Cold Spring Harbor Laboratory |
| locations[0].source.host_organization_lineage | https://openalex.org/I2750212522 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdf |
| locations[0].version | acceptedVersion |
| locations[0].raw_type | posted-content |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | False |
| locations[0].raw_source_name | |
| locations[0].landing_page_url | https://doi.org/10.1101/2021.10.29.466424 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5048318467 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-9102-3480 |
| authorships[0].author.display_name | Lorena Moor |
| authorships[0].countries | CH |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I71824836 |
| authorships[0].affiliations[0].raw_affiliation_string | Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I35440088 |
| authorships[0].affiliations[1].raw_affiliation_string | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland |
| authorships[0].institutions[0].id | https://openalex.org/I35440088 |
| authorships[0].institutions[0].ror | https://ror.org/05a28rw58 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I35440088 |
| authorships[0].institutions[0].country_code | CH |
| authorships[0].institutions[0].display_name | ETH Zurich |
| authorships[0].institutions[1].id | https://openalex.org/I71824836 |
| authorships[0].institutions[1].ror | https://ror.org/02x681a42 |
| authorships[0].institutions[1].type | facility |
| authorships[0].institutions[1].lineage | https://openalex.org/I2799323385, https://openalex.org/I71824836 |
| authorships[0].institutions[1].country_code | CH |
| authorships[0].institutions[1].display_name | Swiss Federal Laboratories for Materials Science and Technology |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Lorena Moor |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland, Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[1].author.id | https://openalex.org/A5016491169 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-0425-0026 |
| authorships[1].author.display_name | Subas Scheibler |
| authorships[1].countries | CH |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I35440088 |
| authorships[1].affiliations[0].raw_affiliation_string | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I71824836 |
| authorships[1].affiliations[1].raw_affiliation_string | Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[1].institutions[0].id | https://openalex.org/I35440088 |
| authorships[1].institutions[0].ror | https://ror.org/05a28rw58 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I35440088 |
| authorships[1].institutions[0].country_code | CH |
| authorships[1].institutions[0].display_name | ETH Zurich |
| authorships[1].institutions[1].id | https://openalex.org/I71824836 |
| authorships[1].institutions[1].ror | https://ror.org/02x681a42 |
| authorships[1].institutions[1].type | facility |
| authorships[1].institutions[1].lineage | https://openalex.org/I2799323385, https://openalex.org/I71824836 |
| authorships[1].institutions[1].country_code | CH |
| authorships[1].institutions[1].display_name | Swiss Federal Laboratories for Materials Science and Technology |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Subas Scheibler |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland, Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[2].author.id | https://openalex.org/A5090791177 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-8568-2674 |
| authorships[2].author.display_name | Lukas R. H. Gerken |
| authorships[2].countries | CH |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I35440088 |
| authorships[2].affiliations[0].raw_affiliation_string | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I71824836 |
| authorships[2].affiliations[1].raw_affiliation_string | Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[2].institutions[0].id | https://openalex.org/I35440088 |
| authorships[2].institutions[0].ror | https://ror.org/05a28rw58 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I35440088 |
| authorships[2].institutions[0].country_code | CH |
| authorships[2].institutions[0].display_name | ETH Zurich |
| authorships[2].institutions[1].id | https://openalex.org/I71824836 |
| authorships[2].institutions[1].ror | https://ror.org/02x681a42 |
| authorships[2].institutions[1].type | facility |
| authorships[2].institutions[1].lineage | https://openalex.org/I2799323385, https://openalex.org/I71824836 |
| authorships[2].institutions[1].country_code | CH |
| authorships[2].institutions[1].display_name | Swiss Federal Laboratories for Materials Science and Technology |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Lukas Gerken |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland, Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[3].author.id | https://openalex.org/A5046810825 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-6842-9204 |
| authorships[3].author.display_name | Konrad Scheffler |
| authorships[3].countries | DE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I884043246 |
| authorships[3].affiliations[0].raw_affiliation_string | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[3].institutions[0].id | https://openalex.org/I884043246 |
| authorships[3].institutions[0].ror | https://ror.org/04bs1pb34 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I884043246 |
| authorships[3].institutions[0].country_code | DE |
| authorships[3].institutions[0].display_name | Hamburg University of Technology |
| authorships[3].institutions[1].id | https://openalex.org/I159176309 |
| authorships[3].institutions[1].ror | https://ror.org/00g30e956 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I159176309 |
| authorships[3].institutions[1].country_code | DE |
| authorships[3].institutions[1].display_name | Universität Hamburg |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Konrad Scheffler |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[4].author.id | https://openalex.org/A5038625029 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-2890-5288 |
| authorships[4].author.display_name | Florian Thieben |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I884043246 |
| authorships[4].affiliations[0].raw_affiliation_string | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[4].institutions[0].id | https://openalex.org/I884043246 |
| authorships[4].institutions[0].ror | https://ror.org/04bs1pb34 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I884043246 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Hamburg University of Technology |
| authorships[4].institutions[1].id | https://openalex.org/I159176309 |
| authorships[4].institutions[1].ror | https://ror.org/00g30e956 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I159176309 |
| authorships[4].institutions[1].country_code | DE |
| authorships[4].institutions[1].display_name | Universität Hamburg |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Florian Thieben |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[5].author.id | https://openalex.org/A5050329207 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-1589-8517 |
| authorships[5].author.display_name | Tobias Knopp |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I884043246 |
| authorships[5].affiliations[0].raw_affiliation_string | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[5].institutions[0].id | https://openalex.org/I884043246 |
| authorships[5].institutions[0].ror | https://ror.org/04bs1pb34 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I884043246 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | Hamburg University of Technology |
| authorships[5].institutions[1].id | https://openalex.org/I159176309 |
| authorships[5].institutions[1].ror | https://ror.org/00g30e956 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I159176309 |
| authorships[5].institutions[1].country_code | DE |
| authorships[5].institutions[1].display_name | Universität Hamburg |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Tobias Knopp |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Institute for Biomedical Imaging, Hamburg University of Technology, Am Schwarzenberg-Campus 3, 21073 Hamburg, Germany |
| authorships[6].author.id | https://openalex.org/A5018301737 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-3018-6796 |
| authorships[6].author.display_name | Inge K. Herrmann |
| authorships[6].countries | CH |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I71824836 |
| authorships[6].affiliations[0].raw_affiliation_string | Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[6].affiliations[1].institution_ids | https://openalex.org/I35440088 |
| authorships[6].affiliations[1].raw_affiliation_string | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland |
| authorships[6].institutions[0].id | https://openalex.org/I35440088 |
| authorships[6].institutions[0].ror | https://ror.org/05a28rw58 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I35440088 |
| authorships[6].institutions[0].country_code | CH |
| authorships[6].institutions[0].display_name | ETH Zurich |
| authorships[6].institutions[1].id | https://openalex.org/I71824836 |
| authorships[6].institutions[1].ror | https://ror.org/02x681a42 |
| authorships[6].institutions[1].type | facility |
| authorships[6].institutions[1].lineage | https://openalex.org/I2799323385, https://openalex.org/I71824836 |
| authorships[6].institutions[1].country_code | CH |
| authorships[6].institutions[1].display_name | Swiss Federal Laboratories for Materials Science and Technology |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Inge K. Herrmann |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland, Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[7].author.id | https://openalex.org/A5091895949 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-0724-764X |
| authorships[7].author.display_name | Fabian H. L. Starsich |
| authorships[7].countries | CH |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I71824836 |
| authorships[7].affiliations[0].raw_affiliation_string | Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I35440088 |
| authorships[7].affiliations[1].raw_affiliation_string | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland |
| authorships[7].institutions[0].id | https://openalex.org/I35440088 |
| authorships[7].institutions[0].ror | https://ror.org/05a28rw58 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I2799323385, https://openalex.org/I35440088 |
| authorships[7].institutions[0].country_code | CH |
| authorships[7].institutions[0].display_name | ETH Zurich |
| authorships[7].institutions[1].id | https://openalex.org/I71824836 |
| authorships[7].institutions[1].ror | https://ror.org/02x681a42 |
| authorships[7].institutions[1].type | facility |
| authorships[7].institutions[1].lineage | https://openalex.org/I2799323385, https://openalex.org/I71824836 |
| authorships[7].institutions[1].country_code | CH |
| authorships[7].institutions[1].display_name | Swiss Federal Laboratories for Materials Science and Technology |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Fabian H. L. Starsich |
| authorships[7].is_corresponding | True |
| authorships[7].raw_affiliation_strings | Nanoparticle Systems Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland, Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdf |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Particle interactions and their effect on magnetic particle imaging and spectroscopy |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T12405 |
| primary_topic.field.id | https://openalex.org/fields/22 |
| primary_topic.field.display_name | Engineering |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2204 |
| primary_topic.subfield.display_name | Biomedical Engineering |
| primary_topic.display_name | Characterization and Applications of Magnetic Nanoparticles |
| related_works | https://openalex.org/W2768378390, https://openalex.org/W1887685947, https://openalex.org/W2987438838, https://openalex.org/W2144781777, https://openalex.org/W1908117345, https://openalex.org/W1977424460, https://openalex.org/W2737178809, https://openalex.org/W2325743067, https://openalex.org/W2352557471, https://openalex.org/W4387376749 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.1101/2021.10.29.466424 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4306402567 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | bioRxiv (Cold Spring Harbor Laboratory) |
| best_oa_location.source.host_organization | https://openalex.org/I2750212522 |
| best_oa_location.source.host_organization_name | Cold Spring Harbor Laboratory |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I2750212522 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdf |
| best_oa_location.version | acceptedVersion |
| best_oa_location.raw_type | posted-content |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | |
| best_oa_location.landing_page_url | https://doi.org/10.1101/2021.10.29.466424 |
| primary_location.id | doi:10.1101/2021.10.29.466424 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4306402567 |
| primary_location.source.issn | |
| primary_location.source.type | repository |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | bioRxiv (Cold Spring Harbor Laboratory) |
| primary_location.source.host_organization | https://openalex.org/I2750212522 |
| primary_location.source.host_organization_name | Cold Spring Harbor Laboratory |
| primary_location.source.host_organization_lineage | https://openalex.org/I2750212522 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | https://www.biorxiv.org/content/biorxiv/early/2021/11/01/2021.10.29.466424.full.pdf |
| primary_location.version | acceptedVersion |
| primary_location.raw_type | posted-content |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | False |
| primary_location.raw_source_name | |
| primary_location.landing_page_url | https://doi.org/10.1101/2021.10.29.466424 |
| publication_date | 2021-11-01 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W1983277479, https://openalex.org/W4230184048, https://openalex.org/W2151752675, https://openalex.org/W2406079808, https://openalex.org/W2015976998, https://openalex.org/W2948935182, https://openalex.org/W2587992676, https://openalex.org/W2786412796, https://openalex.org/W1949636578, https://openalex.org/W2171777801, https://openalex.org/W4250991820, https://openalex.org/W2093718909, https://openalex.org/W3150863119, https://openalex.org/W2550260129, https://openalex.org/W2887669853, https://openalex.org/W2107474730, https://openalex.org/W2883817561, https://openalex.org/W3012646782, https://openalex.org/W1984621896, https://openalex.org/W2079079334, https://openalex.org/W2885113706, https://openalex.org/W2507322519, https://openalex.org/W2072146675, https://openalex.org/W2962156918, https://openalex.org/W2066426749, https://openalex.org/W2062270676, https://openalex.org/W2101293228, https://openalex.org/W2187216610, https://openalex.org/W2158325727, https://openalex.org/W2901415931, https://openalex.org/W4235625120, https://openalex.org/W2170584001 |
| referenced_works_count | 32 |
| abstract_inverted_index., | 235 |
| abstract_inverted_index.2 | 64, 85, 138, 269 |
| abstract_inverted_index.3 | 146, 201, 232, 282 |
| abstract_inverted_index.4 | 54, 92, 148, 203, 234, 284 |
| abstract_inverted_index.O | 53, 91, 147, 202, 233, 283 |
| abstract_inverted_index.a | 79, 225, 239 |
| abstract_inverted_index.Fe | 51, 89, 145, 200, 231, 281 |
| abstract_inverted_index.On | 190 |
| abstract_inverted_index.To | 117 |
| abstract_inverted_index.We | 45, 179 |
| abstract_inverted_index.Zn | 49, 87 |
| abstract_inverted_index.an | 9, 161 |
| abstract_inverted_index.at | 291 |
| abstract_inverted_index.be | 273, 287 |
| abstract_inverted_index.by | 61 |
| abstract_inverted_index.in | 24, 97, 102, 125, 150, 163, 177, 206, 224, 276, 289 |
| abstract_inverted_index.is | 6, 155 |
| abstract_inverted_index.of | 36, 104, 121, 133, 197, 218, 302, 313 |
| abstract_inverted_index.on | 41 |
| abstract_inverted_index.to | 28, 157, 182, 209 |
| abstract_inverted_index.we | 32, 128, 236 |
| abstract_inverted_index.0.4 | 50, 88 |
| abstract_inverted_index.2.6 | 52, 90 |
| abstract_inverted_index.For | 229 |
| abstract_inverted_index.MPI | 43, 265, 303 |
| abstract_inverted_index.MPS | 115, 131, 195, 249 |
| abstract_inverted_index.PBS | 154, 207, 290 |
| abstract_inverted_index.SiO | 63, 84, 137, 268 |
| abstract_inverted_index.The | 67, 83, 165, 216, 258 |
| abstract_inverted_index.and | 2, 47, 56, 136, 152, 167, 251, 278, 298, 309, 320 |
| abstract_inverted_index.for | 8, 78 |
| abstract_inverted_index.not | 286 |
| abstract_inverted_index.our | 314 |
| abstract_inverted_index.the | 34, 42, 71, 94, 107, 114, 119, 130, 134, 191, 194, 243, 248, 252, 296, 311 |
| abstract_inverted_index.via | 12, 256 |
| abstract_inverted_index.was | 221, 261 |
| abstract_inverted_index.PBS, | 279 |
| abstract_inverted_index.PBS. | 153, 178 |
| abstract_inverted_index.This | 293 |
| abstract_inverted_index.all. | 292 |
| abstract_inverted_index.also | 299 |
| abstract_inverted_index.bare | 95, 135, 166 |
| abstract_inverted_index.cell | 227 |
| abstract_inverted_index.from | 247 |
| abstract_inverted_index.more | 126 |
| abstract_inverted_index.only | 111 |
| abstract_inverted_index.same | 259 |
| abstract_inverted_index.such | 37, 305 |
| abstract_inverted_index.this | 181, 219 |
| abstract_inverted_index.thus | 3 |
| abstract_inverted_index.vivo | 25 |
| abstract_inverted_index.(MPS) | 101 |
| abstract_inverted_index.Here, | 31 |
| abstract_inverted_index.could | 237, 272, 285 |
| abstract_inverted_index.hand, | 193 |
| abstract_inverted_index.known | 156 |
| abstract_inverted_index.other | 192 |
| abstract_inverted_index.shell | 69, 108 |
| abstract_inverted_index.terms | 103 |
| abstract_inverted_index.their | 23, 58, 175, 183, 188, 264 |
| abstract_inverted_index.trend | 260 |
| abstract_inverted_index.using | 304 |
| abstract_inverted_index.vivo. | 164 |
| abstract_inverted_index.water | 151, 277 |
| abstract_inverted_index.while | 267 |
| abstract_inverted_index.(MPI). | 16 |
| abstract_inverted_index.Tracer | 1 |
| abstract_inverted_index.actual | 253 |
| abstract_inverted_index.coated | 168 |
| abstract_inverted_index.detect | 238 |
| abstract_inverted_index.during | 22, 187, 263 |
| abstract_inverted_index.effect | 220 |
| abstract_inverted_index.formed | 186 |
| abstract_inverted_index.itself | 110 |
| abstract_inverted_index.limits | 295 |
| abstract_inverted_index.model. | 228 |
| abstract_inverted_index.sample | 96 |
| abstract_inverted_index.showed | 170 |
| abstract_inverted_index.signal | 4, 132, 172, 196, 250, 318 |
| abstract_inverted_index.silica | 68 |
| abstract_inverted_index.strong | 240 |
| abstract_inverted_index.water, | 210 |
| abstract_inverted_index.weakly | 112 |
| abstract_inverted_index.-coated | 86, 139, 270 |
| abstract_inverted_index.ICP-MS. | 257 |
| abstract_inverted_index.against | 141 |
| abstract_inverted_index.between | 242 |
| abstract_inverted_index.changed | 213 |
| abstract_inverted_index.coating | 65 |
| abstract_inverted_index.crucial | 7 |
| abstract_inverted_index.despite | 174 |
| abstract_inverted_index.detail, | 127 |
| abstract_inverted_index.effects | 124 |
| abstract_inverted_index.further | 222 |
| abstract_inverted_index.general | 300 |
| abstract_inverted_index.imaging | 15 |
| abstract_inverted_index.leading | 27 |
| abstract_inverted_index.located | 275 |
| abstract_inverted_index.signal. | 44, 116 |
| abstract_inverted_index.smaller | 80 |
| abstract_inverted_index.tracers | 308 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.However, | 17 |
| abstract_inverted_index.accurate | 10 |
| abstract_inverted_index.affected | 70 |
| abstract_inverted_index.compared | 208 |
| abstract_inverted_index.coupling | 39, 123 |
| abstract_inverted_index.detected | 288 |
| abstract_inverted_index.distance | 60 |
| abstract_inverted_index.however, | 106 |
| abstract_inverted_index.magnetic | 13, 38, 72, 98, 122 |
| abstract_inverted_index.observed | 262 |
| abstract_inverted_index.obtained | 246 |
| abstract_inverted_index.particle | 14, 29, 76, 99, 214, 244 |
| abstract_inverted_index.prepared | 46 |
| abstract_inverted_index.standard | 306 |
| abstract_inverted_index.stronger | 75 |
| abstract_inverted_index.strongly | 204, 212 |
| abstract_inverted_index.variying | 62 |
| abstract_inverted_index.accuracy. | 323 |
| abstract_inverted_index.analysis; | 266 |
| abstract_inverted_index.attribute | 180 |
| abstract_inverted_index.available | 143 |
| abstract_inverted_index.decreased | 205 |
| abstract_inverted_index.diagnosis | 11 |
| abstract_inverted_index.distance. | 82 |
| abstract_inverted_index.excellent | 171 |
| abstract_inverted_index.influence | 35 |
| abstract_inverted_index.mammalian | 226 |
| abstract_inverted_index.mimicking | 160 |
| abstract_inverted_index.phenomena | 40 |
| abstract_inverted_index.precisely | 274 |
| abstract_inverted_index.relevance | 217 |
| abstract_inverted_index.stability | 5, 319 |
| abstract_inverted_index.thickness | 109 |
| abstract_inverted_index.MPI-tracer | 18 |
| abstract_inverted_index.PVP-coated | 144, 199, 230, 280 |
| abstract_inverted_index.advantages | 312 |
| abstract_inverted_index.aggregated | 184 |
| abstract_inverted_index.commercial | 198, 307 |
| abstract_inverted_index.concerning | 317 |
| abstract_inverted_index.controlled | 57 |
| abstract_inverted_index.determined | 255 |
| abstract_inverted_index.diagnostic | 322 |
| abstract_inverted_index.flame-made | 315 |
| abstract_inverted_index.frequently | 20 |
| abstract_inverted_index.highlights | 310 |
| abstract_inverted_index.importance | 120 |
| abstract_inverted_index.indicating | 74, 211 |
| abstract_inverted_index.influenced | 113 |
| abstract_inverted_index.morphology | 185 |
| abstract_inverted_index.properties | 73 |
| abstract_inverted_index.stability, | 173 |
| abstract_inverted_index.thickness. | 66 |
| abstract_inverted_index.ultimately | 321 |
| abstract_inverted_index.Zn-ferrites | 140, 169, 271, 316 |
| abstract_inverted_index.agglomerate | 21 |
| abstract_inverted_index.benchmarked | 129 |
| abstract_inverted_index.destabilize | 158 |
| abstract_inverted_index.discrepancy | 241 |
| abstract_inverted_index.drastically | 294 |
| abstract_inverted_index.investigate | 33, 118 |
| abstract_inverted_index.sensitivity | 297 |
| abstract_inverted_index.applications | 26 |
| abstract_inverted_index.commercially | 142 |
| abstract_inverted_index.interactions | 77 |
| abstract_inverted_index.investigated | 223 |
| abstract_inverted_index.outperformed | 93 |
| abstract_inverted_index.spectroscopy | 100 |
| abstract_inverted_index.agglomeration | 162, 176 |
| abstract_inverted_index.applicability | 301 |
| abstract_inverted_index.characterized | 48 |
| abstract_inverted_index.concentration | 245, 254 |
| abstract_inverted_index.interactions. | 30, 215 |
| abstract_inverted_index.interparticle | 59, 81 |
| abstract_inverted_index.nanoparticles | 19, 55, 149, 159 |
| abstract_inverted_index.signal/noise, | 105 |
| abstract_inverted_index.flame-synthesis. | 189 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5091895949 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 8 |
| corresponding_institution_ids | https://openalex.org/I35440088, https://openalex.org/I71824836 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/6 |
| sustainable_development_goals[0].score | 0.699999988079071 |
| sustainable_development_goals[0].display_name | Clean water and sanitation |
| citation_normalized_percentile.value | 0.19113567 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |