PathIN: an integrated tool for the visualization of pathway interaction networks Article Swipe
George Minadakis
,
Kyproula Christodoulou
,
George Tsouloupas
,
George M. Spyrou
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.csbj.2022.12.028
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.csbj.2022.12.028
PathIN is a web-service that provides an easy and flexible way for rapidly creating pathway-based networks at several functional biological levels: genes, compounds and reactions. The tool is supported by a database repository of reference pathway networks across a large set of species, developed through the freely available information included in the KEGG, Reactome and Wiki Pathways database repositories. PathIN provides networks by means of five diverse methodologies: (a) direct connections between pathways of interest, (b) direct connections as well as the first neighbours of the given pathways, (c) direct connections, the first neighbours and the connections in between them, and (d) two additional methodologies for creating complementary pathway-to-pathway networks that involve additional (missing) pathways that interfere in-between pathways of interest. PathIN is expected to be used as a simple yet informative reference tool for understanding networks of molecular mechanisms related to specific diseases.
Related Topics
Concepts
KEGG
Computer science
Visualization
Set (abstract data type)
Biological pathway
Computational biology
Database
World Wide Web
Data science
Data mining
Biology
Gene
Gene ontology
Biochemistry
Programming language
Gene expression
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.csbj.2022.12.028
- OA Status
- gold
- Cited By
- 9
- References
- 46
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4313377234Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.csbj.2022.12.028Digital Object Identifier
- Title
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PathIN: an integrated tool for the visualization of pathway interaction networksWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-12-18Full publication date if available
- Authors
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George Minadakis, Kyproula Christodoulou, George Tsouloupas, George M. SpyrouList of authors in order
- Landing page
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https://doi.org/10.1016/j.csbj.2022.12.028Publisher landing page
- Open access
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1016/j.csbj.2022.12.028Direct OA link when available
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KEGG, Computer science, Visualization, Set (abstract data type), Biological pathway, Computational biology, Database, World Wide Web, Data science, Data mining, Biology, Gene, Gene ontology, Biochemistry, Programming language, Gene expressionTop concepts (fields/topics) attached by OpenAlex
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9Total citation count in OpenAlex
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2025: 4, 2024: 3, 2023: 2Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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