Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice Article Swipe

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Yuxing Xia , Stefan Prokop , Brach M. Bell , Kimberly-Marie M. Gorion , Cara L. Croft , Lith Nasif , Guilian Xu , Cara J. Riffe , Alyssa N. Manaois , Kevin H. Strang , Stephan Quintin , Giavanna Paterno , Malú G. Tansey , David Borchelt , Todd E. Golde , Benoit I. Giasson ·

YOU? · · 2022 · Open Access · · DOI: https://doi.org/10.1038/s42003-022-03373-1

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Genetically modified mouse Transgene Phenotype Endogeny Tau pathology Biology Tau protein Neurodegeneration Neurotoxicity Pathology Neuroscience Cell biology Medicine Disease Alzheimer's disease Genetics Gene Toxicity Internal medicine Biochemistry

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Type: article
Language: en
Landing Page: https://doi.org/10.1038/s42003-022-03373-1
PDF: https://www.nature.com/articles/s42003-022-03373-1.pdf
OA Status: gold
Cited By: 16
References: 103
Related Works: 10
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DOI: https://doi.org/10.1038/s42003-022-03373-1

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Title: Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice

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Type: article

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Language: en

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Publication year: 2022

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Publication date: 2022-05-12

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Authors: Yuxing Xia, Stefan Prokop, Brach M. Bell, Kimberly-Marie M. Gorion, Cara L. Croft, Lith Nasif, Guilian Xu, Cara J. Riffe, Alyssa N. Manaois, Kevin H. Strang, Stephan Quintin, Giavanna Paterno, Malú G. Tansey, David Borchelt, Todd E. Golde, Benoit I. Giasson

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Landing page: https://doi.org/10.1038/s42003-022-03373-1

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PDF URL: https://www.nature.com/articles/s42003-022-03373-1.pdf

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Concepts: Genetically modified mouse, Transgene, Phenotype, Endogeny, Tau pathology, Biology, Tau protein, Neurodegeneration, Neurotoxicity, Pathology, Neuroscience, Cell biology, Medicine, Disease, Alzheimer's disease, Genetics, Gene, Toxicity, Internal medicine, Biochemistry

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Cited by: 16

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Citations by year (recent): 2025: 7, 2024: 4, 2023: 5

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