Patient Safety during Propofol Sedation before and after Implementation of Capnography Monitoring Article Swipe
Volkan Baytaş
,
Çağıl Vural
,
Menekşe Özçelik
,
Rafael Torrejón Torres
,
Rhodri Saunders
,
Neslihan Alkış
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/jcm12185959
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/jcm12185959
Endoscopic procedures are routinely applied to cancer screening programs and surveillance. The preferred technique is usually deep sedation with propofol being a convenient agent allowing for a quicker patient recovery while maintaining a similar safety profile compared to traditional agents. However, adverse events, including respiratory depression and consequent undesirable cardiovascular side effects, may occur. The goal of this work is to evaluate the patient safety impact of adding capnography during endoscopic procedures under deep propofol sedation. Data were retrospectively collected from patients undergoing deep, procedural sedation for gastrointestinal (GI) endoscopy in October 2019 to January 2021 in a single Turkish university hospital. Included in the analysis were all adult patients classified by the American Society of Anesthesiologists (ASA) as I–IV, who were scheduled for GI endoscopy utilizing propofol alone or in combination. Data on 1840 patients were collected, of whom 1610 (730 pre- and 880 post-capnography implemention) met inclusion criteria. The primary outcome was a change in the composite incidence of mild oxygen desaturation (SpO2 75–90% for 60 s), bradycardia (25% from baseline). Without capnography, on average, 7.5 events of the primary endpoint were observed per 100 procedures and 2.9 with additional capnography monitoring (p < 0.001). A significant reduction was observed for mild oxygen desaturation, with a resulting odds ratio of 0.25 (95% CI 0.14 to 0.46). ASA I patients had the highest difference in combined incidence of any oxygen desaturation of 5.85% in the pre-capnography group and 0.64% in the post-capnography group. Although procedural sedation using propofol is not associated with severe adverse events, the incidence of composite adverse events could be reduced with the addition of capnography monitoring.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/jcm12185959
- https://www.mdpi.com/2077-0383/12/18/5959/pdf?version=1694661988
- OA Status
- gold
- Cited By
- 6
- References
- 24
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4386743819
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4386743819Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/jcm12185959Digital Object Identifier
- Title
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Patient Safety during Propofol Sedation before and after Implementation of Capnography MonitoringWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-09-14Full publication date if available
- Authors
-
Volkan Baytaş, Çağıl Vural, Menekşe Özçelik, Rafael Torrejón Torres, Rhodri Saunders, Neslihan AlkışList of authors in order
- Landing page
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https://doi.org/10.3390/jcm12185959Publisher landing page
- PDF URL
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https://www.mdpi.com/2077-0383/12/18/5959/pdf?version=1694661988Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/2077-0383/12/18/5959/pdf?version=1694661988Direct OA link when available
- Concepts
-
Medicine, Propofol, Capnography, Sedation, Anesthesia, Patient safety, Intensive care medicine, Health care, Economics, Economic growthTop concepts (fields/topics) attached by OpenAlex
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6Total citation count in OpenAlex
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2025: 2, 2024: 4Per-year citation counts (last 5 years)
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24Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| primary_location.raw_source_name | Journal of Clinical Medicine |
| primary_location.landing_page_url | https://doi.org/10.3390/jcm12185959 |
| publication_date | 2023-09-14 |
| publication_year | 2023 |
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