Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats Article Swipe
Pengyan Wang
,
Can Yue
,
Kefang Liu
,
Dan Lü
,
Sai Liu
,
Sijia Yao
,
Xin Li
,
Xiaoling Su
,
Keyi Ren
,
Yan Chai
,
Jianxun Qi
,
Yingze Zhao
,
Yongliang Lou
,
Zeyu Sun
,
George F. Gao
,
William J. Liu
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.4049/jimmunol.2100350
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.4049/jimmunol.2100350
Marsupials are one of three major mammalian lineages that include the placental eutherians and the egg-laying monotremes. The marsupial brushtail possum is an important protected species in the Australian forest ecosystem. Molecules encoded by the MHC genes are essential mediators of adaptive immune responses in virus–host interactions. Yet, nothing is known about the peptide presentation features of any marsupial MHC class I (MHC I). This study identified a series of possum MHC I Trvu-UB*01:01 binding peptides derived from wobbly possum disease virus (WPDV), a lethal virus of both captive and feral possum populations, and unveiled the structure of marsupial peptide/MHC I complex. Notably, we found the two brushtail possum–specific insertions, the 3-aa Ile52Glu53Arg54 and 1-aa Arg154 insertions are located in the Trvu-UB*01:01 peptide binding groove (PBG). The 3-aa insertion plays a pivotal role in maintaining the stability of the N terminus of Trvu-UB*01:01 PBG. This aspect of marsupial PBG is unexpectedly similar to the bat MHC I Ptal-N*01:01 and is shared with lower vertebrates from elasmobranch to monotreme, indicating an evolution hotspot that may have emerged from the pathogen–host interactions. Residue Arg154 insertion, located in the α2 helix, is available for TCR recognition, and it has a particular influence on promoting the anchoring of peptide WPDV-12. These findings add significantly to our understanding of adaptive immunity in marsupials and its evolution in vertebrates. Our findings have the potential to impact the conservation of the protected species brushtail possum and other marsupial species.
Related Topics
Concepts
Marsupial
Immune system
Major histocompatibility complex
Biology
MHC class I
MHC class II
Immunology
Evolutionary biology
Zoology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4049/jimmunol.2100350
- https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdf
- OA Status
- bronze
- Cited By
- 6
- References
- 68
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3199482961
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3199482961Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.4049/jimmunol.2100350Digital Object Identifier
- Title
-
Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with BatsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-09-17Full publication date if available
- Authors
-
Pengyan Wang, Can Yue, Kefang Liu, Dan Lü, Sai Liu, Sijia Yao, Xin Li, Xiaoling Su, Keyi Ren, Yan Chai, Jianxun Qi, Yingze Zhao, Yongliang Lou, Zeyu Sun, George F. Gao, William J. LiuList of authors in order
- Landing page
-
https://doi.org/10.4049/jimmunol.2100350Publisher landing page
- PDF URL
-
https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdfDirect OA link when available
- Concepts
-
Marsupial, Immune system, Major histocompatibility complex, Biology, MHC class I, MHC class II, Immunology, Evolutionary biology, ZoologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 2, 2023: 1, 2022: 2Per-year citation counts (last 5 years)
- References (count)
-
68Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3199482961 |
|---|---|
| doi | https://doi.org/10.4049/jimmunol.2100350 |
| ids.doi | https://doi.org/10.4049/jimmunol.2100350 |
| ids.mag | 3199482961 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/34535575 |
| ids.openalex | https://openalex.org/W3199482961 |
| fwci | 0.93611784 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000818 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Animals |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D017951 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Antigen Presentation |
| mesh[2].qualifier_ui | Q000276 |
| mesh[2].descriptor_ui | D000956 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | immunology |
| mesh[2].descriptor_name | Antigens, Viral |
| mesh[3].qualifier_ui | Q000378 |
| mesh[3].descriptor_ui | D000956 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | metabolism |
| mesh[3].descriptor_name | Antigens, Viral |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D001315 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Australia |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D005075 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Biological Evolution |
| mesh[6].qualifier_ui | Q000276 |
| mesh[6].descriptor_ui | D002685 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | immunology |
| mesh[6].descriptor_name | Chiroptera |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D003001 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Cloning, Molecular |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D003247 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Conservation of Natural Resources |
| mesh[9].qualifier_ui | Q000235 |
| mesh[9].descriptor_ui | D015395 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | genetics |
| mesh[9].descriptor_name | Histocompatibility Antigens Class I |
| mesh[10].qualifier_ui | Q000378 |
| mesh[10].descriptor_ui | D015395 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | metabolism |
| mesh[10].descriptor_name | Histocompatibility Antigens Class I |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D054884 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Host-Pathogen Interactions |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D008322 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Mammals |
| mesh[13].qualifier_ui | Q000502 |
| mesh[13].descriptor_ui | D028381 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | physiology |
| mesh[13].descriptor_name | Nidovirales |
| mesh[14].qualifier_ui | Q000276 |
| mesh[14].descriptor_ui | D030341 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | immunology |
| mesh[14].descriptor_name | Nidovirales Infections |
| mesh[15].qualifier_ui | Q000378 |
| mesh[15].descriptor_ui | D010455 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | metabolism |
| mesh[15].descriptor_name | Peptides |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D011485 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Protein Binding |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D011487 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Protein Conformation |
| mesh[18].qualifier_ui | Q000276 |
| mesh[18].descriptor_ui | D048330 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | immunology |
| mesh[18].descriptor_name | Trichosurus |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D000818 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Animals |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D017951 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Antigen Presentation |
| mesh[21].qualifier_ui | Q000276 |
| mesh[21].descriptor_ui | D000956 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | immunology |
| mesh[21].descriptor_name | Antigens, Viral |
| mesh[22].qualifier_ui | Q000378 |
| mesh[22].descriptor_ui | D000956 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | metabolism |
| mesh[22].descriptor_name | Antigens, Viral |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D001315 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Australia |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D005075 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Biological Evolution |
| mesh[25].qualifier_ui | Q000276 |
| mesh[25].descriptor_ui | D002685 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | immunology |
| mesh[25].descriptor_name | Chiroptera |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D003001 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Cloning, Molecular |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D003247 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Conservation of Natural Resources |
| mesh[28].qualifier_ui | Q000235 |
| mesh[28].descriptor_ui | D015395 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | genetics |
| mesh[28].descriptor_name | Histocompatibility Antigens Class I |
| mesh[29].qualifier_ui | Q000378 |
| mesh[29].descriptor_ui | D015395 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | metabolism |
| mesh[29].descriptor_name | Histocompatibility Antigens Class I |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D054884 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Host-Pathogen Interactions |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D008322 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Mammals |
| mesh[32].qualifier_ui | Q000502 |
| mesh[32].descriptor_ui | D028381 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | physiology |
| mesh[32].descriptor_name | Nidovirales |
| mesh[33].qualifier_ui | Q000276 |
| mesh[33].descriptor_ui | D030341 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | immunology |
| mesh[33].descriptor_name | Nidovirales Infections |
| mesh[34].qualifier_ui | Q000378 |
| mesh[34].descriptor_ui | D010455 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | metabolism |
| mesh[34].descriptor_name | Peptides |
| mesh[35].qualifier_ui | |
| mesh[35].descriptor_ui | D011485 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | |
| mesh[35].descriptor_name | Protein Binding |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D011487 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Protein Conformation |
| mesh[37].qualifier_ui | Q000276 |
| mesh[37].descriptor_ui | D048330 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | immunology |
| mesh[37].descriptor_name | Trichosurus |
| type | article |
| title | Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats |
| awards[0].id | https://openalex.org/G3920732832 |
| awards[0].funder_id | https://openalex.org/F4320321001 |
| awards[0].display_name | |
| awards[0].funder_award_id | 81971501 |
| awards[0].funder_display_name | National Natural Science Foundation of China |
| biblio.issue | 8 |
| biblio.volume | 207 |
| biblio.last_page | 2178 |
| biblio.first_page | 2167 |
| topics[0].id | https://openalex.org/T11171 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9987999796867371 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | Diabetes and associated disorders |
| topics[1].id | https://openalex.org/T11495 |
| topics[1].field.id | https://openalex.org/fields/11 |
| topics[1].field.display_name | Agricultural and Biological Sciences |
| topics[1].score | 0.9958000183105469 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1103 |
| topics[1].subfield.display_name | Animal Science and Zoology |
| topics[1].display_name | Animal Virus Infections Studies |
| topics[2].id | https://openalex.org/T10031 |
| topics[2].field.id | https://openalex.org/fields/24 |
| topics[2].field.display_name | Immunology and Microbiology |
| topics[2].score | 0.995199978351593 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2403 |
| topics[2].subfield.display_name | Immunology |
| topics[2].display_name | T-cell and B-cell Immunology |
| funders[0].id | https://openalex.org/F4320321001 |
| funders[0].ror | https://ror.org/01h0zpd94 |
| funders[0].display_name | National Natural Science Foundation of China |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2777042810 |
| concepts[0].level | 2 |
| concepts[0].score | 0.7234758138656616 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q25336 |
| concepts[0].display_name | Marsupial |
| concepts[1].id | https://openalex.org/C8891405 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6881844401359558 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1059 |
| concepts[1].display_name | Immune system |
| concepts[2].id | https://openalex.org/C207936829 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6267408132553101 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q423163 |
| concepts[2].display_name | Major histocompatibility complex |
| concepts[3].id | https://openalex.org/C86803240 |
| concepts[3].level | 0 |
| concepts[3].score | 0.5930977463722229 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[3].display_name | Biology |
| concepts[4].id | https://openalex.org/C170627219 |
| concepts[4].level | 4 |
| concepts[4].score | 0.5112950801849365 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q13218497 |
| concepts[4].display_name | MHC class I |
| concepts[5].id | https://openalex.org/C2778814158 |
| concepts[5].level | 4 |
| concepts[5].score | 0.4713665246963501 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q959350 |
| concepts[5].display_name | MHC class II |
| concepts[6].id | https://openalex.org/C203014093 |
| concepts[6].level | 1 |
| concepts[6].score | 0.41926687955856323 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[6].display_name | Immunology |
| concepts[7].id | https://openalex.org/C78458016 |
| concepts[7].level | 1 |
| concepts[7].score | 0.37647897005081177 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q840400 |
| concepts[7].display_name | Evolutionary biology |
| concepts[8].id | https://openalex.org/C90856448 |
| concepts[8].level | 1 |
| concepts[8].score | 0.3729982078075409 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q431 |
| concepts[8].display_name | Zoology |
| keywords[0].id | https://openalex.org/keywords/marsupial |
| keywords[0].score | 0.7234758138656616 |
| keywords[0].display_name | Marsupial |
| keywords[1].id | https://openalex.org/keywords/immune-system |
| keywords[1].score | 0.6881844401359558 |
| keywords[1].display_name | Immune system |
| keywords[2].id | https://openalex.org/keywords/major-histocompatibility-complex |
| keywords[2].score | 0.6267408132553101 |
| keywords[2].display_name | Major histocompatibility complex |
| keywords[3].id | https://openalex.org/keywords/biology |
| keywords[3].score | 0.5930977463722229 |
| keywords[3].display_name | Biology |
| keywords[4].id | https://openalex.org/keywords/mhc-class-i |
| keywords[4].score | 0.5112950801849365 |
| keywords[4].display_name | MHC class I |
| keywords[5].id | https://openalex.org/keywords/mhc-class-ii |
| keywords[5].score | 0.4713665246963501 |
| keywords[5].display_name | MHC class II |
| keywords[6].id | https://openalex.org/keywords/immunology |
| keywords[6].score | 0.41926687955856323 |
| keywords[6].display_name | Immunology |
| keywords[7].id | https://openalex.org/keywords/evolutionary-biology |
| keywords[7].score | 0.37647897005081177 |
| keywords[7].display_name | Evolutionary biology |
| keywords[8].id | https://openalex.org/keywords/zoology |
| keywords[8].score | 0.3729982078075409 |
| keywords[8].display_name | Zoology |
| language | en |
| locations[0].id | doi:10.4049/jimmunol.2100350 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S38008053 |
| locations[0].source.issn | 0022-1767, 1550-6606 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0022-1767 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | The Journal of Immunology |
| locations[0].source.host_organization | https://openalex.org/P4320800377 |
| locations[0].source.host_organization_name | American Association of Immunologists |
| locations[0].source.host_organization_lineage | https://openalex.org/P4320800377 |
| locations[0].source.host_organization_lineage_names | American Association of Immunologists |
| locations[0].license | |
| locations[0].pdf_url | https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | The Journal of Immunology |
| locations[0].landing_page_url | https://doi.org/10.4049/jimmunol.2100350 |
| locations[1].id | pmid:34535575 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of immunology (Baltimore, Md. : 1950) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/34535575 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5103115705 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-8967-986X |
| authorships[0].author.display_name | Pengyan Wang |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I27781120 |
| authorships[0].affiliations[0].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I4210140986 |
| authorships[0].affiliations[1].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[0].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[0].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[0].institutions[0].type | government |
| authorships[0].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[0].institutions[1].id | https://openalex.org/I27781120 |
| authorships[0].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[0].institutions[1].country_code | CN |
| authorships[0].institutions[1].display_name | Wenzhou Medical University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Pengyan Wang |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[1].author.id | https://openalex.org/A5109436194 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Can Yue |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].raw_affiliation_string | Savaid Medical School, University of Chinese Academy of Science, Beijing, China |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I4210140986 |
| authorships[1].affiliations[1].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[1].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[1].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[1].institutions[0].type | government |
| authorships[1].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Can Yue |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, Savaid Medical School, University of Chinese Academy of Science, Beijing, China |
| authorships[2].author.id | https://openalex.org/A5078521125 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-9076-2647 |
| authorships[2].author.display_name | Kefang Liu |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[2].affiliations[0].raw_affiliation_string | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[2].institutions[0].id | https://openalex.org/I19820366 |
| authorships[2].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[2].institutions[0].type | government |
| authorships[2].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[2].institutions[1].id | https://openalex.org/I4210134982 |
| authorships[2].institutions[1].ror | https://ror.org/047yhep71 |
| authorships[2].institutions[1].type | facility |
| authorships[2].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[2].institutions[1].country_code | CN |
| authorships[2].institutions[1].display_name | Institute of Microbiology |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Kefang Liu |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[3].author.id | https://openalex.org/A5011946503 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-4531-3599 |
| authorships[3].author.display_name | Dan Lü |
| authorships[3].affiliations[0].raw_affiliation_string | Savaid Medical School, University of Chinese Academy of Science, Beijing, China |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Dan Lu |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Savaid Medical School, University of Chinese Academy of Science, Beijing, China |
| authorships[4].author.id | https://openalex.org/A5100611656 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-1611-2643 |
| authorships[4].author.display_name | Sai Liu |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210140986 |
| authorships[4].affiliations[0].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[4].affiliations[1].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[4].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[4].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[4].institutions[0].type | government |
| authorships[4].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[4].institutions[1].id | https://openalex.org/I27781120 |
| authorships[4].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[4].institutions[1].country_code | CN |
| authorships[4].institutions[1].display_name | Wenzhou Medical University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Sai Liu |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[5].author.id | https://openalex.org/A5069864544 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-4919-2483 |
| authorships[5].author.display_name | Sijia Yao |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210140986 |
| authorships[5].affiliations[0].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[5].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[5].affiliations[1].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[5].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[5].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[5].institutions[0].type | government |
| authorships[5].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[5].institutions[1].id | https://openalex.org/I27781120 |
| authorships[5].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[5].institutions[1].country_code | CN |
| authorships[5].institutions[1].display_name | Wenzhou Medical University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Sijia Yao |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[6].author.id | https://openalex.org/A5100354099 |
| authorships[6].author.orcid | https://orcid.org/0009-0007-7464-7578 |
| authorships[6].author.display_name | Xin Li |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210140986 |
| authorships[6].affiliations[0].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[6].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[6].affiliations[1].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[6].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[6].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[6].institutions[0].type | government |
| authorships[6].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[6].institutions[1].id | https://openalex.org/I27781120 |
| authorships[6].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[6].institutions[1].country_code | CN |
| authorships[6].institutions[1].display_name | Wenzhou Medical University |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Xin Li |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[7].author.id | https://openalex.org/A5077616953 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-5541-8338 |
| authorships[7].author.display_name | Xiaoling Su |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I76130692 |
| authorships[7].affiliations[0].raw_affiliation_string | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[7].institutions[0].id | https://openalex.org/I76130692 |
| authorships[7].institutions[0].ror | https://ror.org/00a2xv884 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I76130692 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Zhejiang University |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Xiaoling Su |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[8].author.id | https://openalex.org/A5063726474 |
| authorships[8].author.orcid | |
| authorships[8].author.display_name | Keyi Ren |
| authorships[8].countries | CN |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I76130692 |
| authorships[8].affiliations[0].raw_affiliation_string | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[8].institutions[0].id | https://openalex.org/I76130692 |
| authorships[8].institutions[0].ror | https://ror.org/00a2xv884 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I76130692 |
| authorships[8].institutions[0].country_code | CN |
| authorships[8].institutions[0].display_name | Zhejiang University |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Keyi Ren |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[9].author.id | https://openalex.org/A5022797656 |
| authorships[9].author.orcid | https://orcid.org/0000-0002-1912-3620 |
| authorships[9].author.display_name | Yan Chai |
| authorships[9].countries | CN |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[9].affiliations[0].raw_affiliation_string | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[9].institutions[0].id | https://openalex.org/I19820366 |
| authorships[9].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[9].institutions[0].type | government |
| authorships[9].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[9].institutions[0].country_code | CN |
| authorships[9].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[9].institutions[1].id | https://openalex.org/I4210134982 |
| authorships[9].institutions[1].ror | https://ror.org/047yhep71 |
| authorships[9].institutions[1].type | facility |
| authorships[9].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[9].institutions[1].country_code | CN |
| authorships[9].institutions[1].display_name | Institute of Microbiology |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Yan Chai |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[10].author.id | https://openalex.org/A5087385265 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-9358-4732 |
| authorships[10].author.display_name | Jianxun Qi |
| authorships[10].countries | CN |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[10].affiliations[0].raw_affiliation_string | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[10].institutions[0].id | https://openalex.org/I19820366 |
| authorships[10].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[10].institutions[0].type | government |
| authorships[10].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[10].institutions[0].country_code | CN |
| authorships[10].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[10].institutions[1].id | https://openalex.org/I4210134982 |
| authorships[10].institutions[1].ror | https://ror.org/047yhep71 |
| authorships[10].institutions[1].type | facility |
| authorships[10].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[10].institutions[1].country_code | CN |
| authorships[10].institutions[1].display_name | Institute of Microbiology |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Jianxun Qi |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[11].author.id | https://openalex.org/A5101961660 |
| authorships[11].author.orcid | https://orcid.org/0000-0003-2406-1855 |
| authorships[11].author.display_name | Yingze Zhao |
| authorships[11].countries | CN |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I4210140986 |
| authorships[11].affiliations[0].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[11].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[11].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[11].institutions[0].type | government |
| authorships[11].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[11].institutions[0].country_code | CN |
| authorships[11].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Yingze Zhao |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[12].author.id | https://openalex.org/A5083078214 |
| authorships[12].author.orcid | https://orcid.org/0000-0003-4198-0001 |
| authorships[12].author.display_name | Yongliang Lou |
| authorships[12].countries | CN |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I27781120 |
| authorships[12].affiliations[0].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[12].institutions[0].id | https://openalex.org/I27781120 |
| authorships[12].institutions[0].ror | https://ror.org/00rd5t069 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I27781120 |
| authorships[12].institutions[0].country_code | CN |
| authorships[12].institutions[0].display_name | Wenzhou Medical University |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Yongliang Lou |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[13].author.id | https://openalex.org/A5085426091 |
| authorships[13].author.orcid | https://orcid.org/0000-0003-0218-2277 |
| authorships[13].author.display_name | Zeyu Sun |
| authorships[13].countries | CN |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I76130692 |
| authorships[13].affiliations[0].raw_affiliation_string | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[13].institutions[0].id | https://openalex.org/I76130692 |
| authorships[13].institutions[0].ror | https://ror.org/00a2xv884 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I76130692 |
| authorships[13].institutions[0].country_code | CN |
| authorships[13].institutions[0].display_name | Zhejiang University |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Zeyu Sun |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China |
| authorships[14].author.id | https://openalex.org/A5015873777 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-3869-615X |
| authorships[14].author.display_name | George F. Gao |
| authorships[14].countries | CN |
| authorships[14].affiliations[0].raw_affiliation_string | Savaid Medical School, University of Chinese Academy of Science, Beijing, China |
| authorships[14].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[14].affiliations[1].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[14].affiliations[2].institution_ids | https://openalex.org/I4210140986 |
| authorships[14].affiliations[2].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[14].affiliations[3].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[14].affiliations[3].raw_affiliation_string | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China |
| authorships[14].institutions[0].id | https://openalex.org/I19820366 |
| authorships[14].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[14].institutions[0].type | government |
| authorships[14].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[14].institutions[0].country_code | CN |
| authorships[14].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[14].institutions[1].id | https://openalex.org/I4210134982 |
| authorships[14].institutions[1].ror | https://ror.org/047yhep71 |
| authorships[14].institutions[1].type | facility |
| authorships[14].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210134982 |
| authorships[14].institutions[1].country_code | CN |
| authorships[14].institutions[1].display_name | Institute of Microbiology |
| authorships[14].institutions[2].id | https://openalex.org/I4210140986 |
| authorships[14].institutions[2].ror | https://ror.org/04b1sh213 |
| authorships[14].institutions[2].type | government |
| authorships[14].institutions[2].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[14].institutions[2].country_code | CN |
| authorships[14].institutions[2].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[14].institutions[3].id | https://openalex.org/I27781120 |
| authorships[14].institutions[3].ror | https://ror.org/00rd5t069 |
| authorships[14].institutions[3].type | education |
| authorships[14].institutions[3].lineage | https://openalex.org/I27781120 |
| authorships[14].institutions[3].country_code | CN |
| authorships[14].institutions[3].display_name | Wenzhou Medical University |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | George F Gao |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, Savaid Medical School, University of Chinese Academy of Science, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[15].author.id | https://openalex.org/A5113795755 |
| authorships[15].author.orcid | |
| authorships[15].author.display_name | William J. Liu |
| authorships[15].countries | CN |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I4210140986 |
| authorships[15].affiliations[0].raw_affiliation_string | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China |
| authorships[15].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[15].affiliations[1].raw_affiliation_string | School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[15].institutions[0].id | https://openalex.org/I4210140986 |
| authorships[15].institutions[0].ror | https://ror.org/04b1sh213 |
| authorships[15].institutions[0].type | government |
| authorships[15].institutions[0].lineage | https://openalex.org/I184490438, https://openalex.org/I4210127390, https://openalex.org/I4210140986, https://openalex.org/I4210151987 |
| authorships[15].institutions[0].country_code | CN |
| authorships[15].institutions[0].display_name | National Institute for Viral Disease Control and Prevention |
| authorships[15].institutions[1].id | https://openalex.org/I27781120 |
| authorships[15].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[15].institutions[1].type | education |
| authorships[15].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[15].institutions[1].country_code | CN |
| authorships[15].institutions[1].display_name | Wenzhou Medical University |
| authorships[15].author_position | last |
| authorships[15].raw_author_name | William J Liu |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdf |
| open_access.oa_status | bronze |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11171 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9987999796867371 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | Diabetes and associated disorders |
| related_works | https://openalex.org/W37295251, https://openalex.org/W1840653008, https://openalex.org/W2977793531, https://openalex.org/W2023967363, https://openalex.org/W1939527068, https://openalex.org/W2154173448, https://openalex.org/W2126139339, https://openalex.org/W2168688111, https://openalex.org/W2070684866, https://openalex.org/W4281625971 |
| cited_by_count | 6 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 1 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 2 |
| locations_count | 2 |
| best_oa_location.id | doi:10.4049/jimmunol.2100350 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S38008053 |
| best_oa_location.source.issn | 0022-1767, 1550-6606 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0022-1767 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | The Journal of Immunology |
| best_oa_location.source.host_organization | https://openalex.org/P4320800377 |
| best_oa_location.source.host_organization_name | American Association of Immunologists |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4320800377 |
| best_oa_location.source.host_organization_lineage_names | American Association of Immunologists |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | The Journal of Immunology |
| best_oa_location.landing_page_url | https://doi.org/10.4049/jimmunol.2100350 |
| primary_location.id | doi:10.4049/jimmunol.2100350 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S38008053 |
| primary_location.source.issn | 0022-1767, 1550-6606 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0022-1767 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | The Journal of Immunology |
| primary_location.source.host_organization | https://openalex.org/P4320800377 |
| primary_location.source.host_organization_name | American Association of Immunologists |
| primary_location.source.host_organization_lineage | https://openalex.org/P4320800377 |
| primary_location.source.host_organization_lineage_names | American Association of Immunologists |
| primary_location.license | |
| primary_location.pdf_url | https://www.jimmunol.org/content/jimmunol/207/8/2167.full.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | The Journal of Immunology |
| primary_location.landing_page_url | https://doi.org/10.4049/jimmunol.2100350 |
| publication_date | 2021-09-17 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2070740026, https://openalex.org/W2128419388, https://openalex.org/W2030645532, https://openalex.org/W2775572674, https://openalex.org/W2915235806, https://openalex.org/W2738232572, https://openalex.org/W2039737557, https://openalex.org/W2810416640, https://openalex.org/W2048252485, https://openalex.org/W2172321719, https://openalex.org/W1970788482, https://openalex.org/W1499414309, https://openalex.org/W2049567307, https://openalex.org/W2043611945, https://openalex.org/W2264265766, https://openalex.org/W1966838457, https://openalex.org/W2174353003, https://openalex.org/W2045732993, https://openalex.org/W2801840763, https://openalex.org/W2038132052, https://openalex.org/W1975768674, https://openalex.org/W2558466790, https://openalex.org/W2972771701, https://openalex.org/W4230969272, https://openalex.org/W2048912867, https://openalex.org/W2985387940, https://openalex.org/W1966554885, https://openalex.org/W2025575688, https://openalex.org/W2131893627, https://openalex.org/W2168688111, https://openalex.org/W2896324646, https://openalex.org/W3033977655, https://openalex.org/W2841483200, https://openalex.org/W1539796472, https://openalex.org/W2790955116, https://openalex.org/W2144081223, https://openalex.org/W2180229411, https://openalex.org/W2139397135, https://openalex.org/W1996450030, https://openalex.org/W2509965517, https://openalex.org/W1574660386, https://openalex.org/W2158266834, https://openalex.org/W2961879920, https://openalex.org/W2042349371, https://openalex.org/W2115090019, https://openalex.org/W2006552475, https://openalex.org/W2055097234, https://openalex.org/W2027778171, https://openalex.org/W2149771342, https://openalex.org/W2058411257, https://openalex.org/W2140267818, https://openalex.org/W3110165475, https://openalex.org/W1964488044, https://openalex.org/W2155593333, https://openalex.org/W2057857896, https://openalex.org/W1997359957, https://openalex.org/W2883821166, https://openalex.org/W2111537088, https://openalex.org/W2981732342, https://openalex.org/W3131090694, https://openalex.org/W2139445045, https://openalex.org/W1980048816, https://openalex.org/W2998293965, https://openalex.org/W3046379362, https://openalex.org/W1823109592, https://openalex.org/W2075915863, https://openalex.org/W1968383985, https://openalex.org/W2102040350 |
| referenced_works_count | 68 |
| abstract_inverted_index.I | 62, 73, 101, 157 |
| abstract_inverted_index.N | 140 |
| abstract_inverted_index.a | 68, 84, 131, 197 |
| abstract_inverted_index.an | 23, 170 |
| abstract_inverted_index.by | 34 |
| abstract_inverted_index.in | 27, 45, 120, 134, 185, 217, 222 |
| abstract_inverted_index.is | 22, 50, 150, 160, 189 |
| abstract_inverted_index.it | 195 |
| abstract_inverted_index.of | 4, 41, 57, 70, 87, 98, 138, 142, 147, 204, 214, 233 |
| abstract_inverted_index.on | 200 |
| abstract_inverted_index.to | 153, 167, 211, 229 |
| abstract_inverted_index.we | 104 |
| abstract_inverted_index.I). | 64 |
| abstract_inverted_index.MHC | 36, 60, 72, 156 |
| abstract_inverted_index.Our | 224 |
| abstract_inverted_index.PBG | 149 |
| abstract_inverted_index.TCR | 192 |
| abstract_inverted_index.The | 18, 127 |
| abstract_inverted_index.add | 209 |
| abstract_inverted_index.and | 14, 90, 94, 114, 159, 194, 219, 239 |
| abstract_inverted_index.any | 58 |
| abstract_inverted_index.are | 2, 38, 118 |
| abstract_inverted_index.bat | 155 |
| abstract_inverted_index.for | 191 |
| abstract_inverted_index.has | 196 |
| abstract_inverted_index.its | 220 |
| abstract_inverted_index.may | 174 |
| abstract_inverted_index.one | 3 |
| abstract_inverted_index.our | 212 |
| abstract_inverted_index.the | 11, 15, 28, 35, 53, 96, 106, 111, 121, 136, 139, 154, 178, 186, 202, 227, 231, 234 |
| abstract_inverted_index.two | 107 |
| abstract_inverted_index.α2 | 187 |
| abstract_inverted_index.(MHC | 63 |
| abstract_inverted_index.1-aa | 115 |
| abstract_inverted_index.3-aa | 112, 128 |
| abstract_inverted_index.PBG. | 144 |
| abstract_inverted_index.This | 65, 145 |
| abstract_inverted_index.Yet, | 48 |
| abstract_inverted_index.both | 88 |
| abstract_inverted_index.from | 78, 165, 177 |
| abstract_inverted_index.have | 175, 226 |
| abstract_inverted_index.role | 133 |
| abstract_inverted_index.that | 9, 173 |
| abstract_inverted_index.with | 162 |
| abstract_inverted_index.These | 207 |
| abstract_inverted_index.about | 52 |
| abstract_inverted_index.class | 61 |
| abstract_inverted_index.feral | 91 |
| abstract_inverted_index.found | 105 |
| abstract_inverted_index.genes | 37 |
| abstract_inverted_index.known | 51 |
| abstract_inverted_index.lower | 163 |
| abstract_inverted_index.major | 6 |
| abstract_inverted_index.other | 240 |
| abstract_inverted_index.plays | 130 |
| abstract_inverted_index.study | 66 |
| abstract_inverted_index.three | 5 |
| abstract_inverted_index.virus | 82, 86 |
| abstract_inverted_index.(PBG). | 126 |
| abstract_inverted_index.Arg154 | 116, 182 |
| abstract_inverted_index.aspect | 146 |
| abstract_inverted_index.forest | 30 |
| abstract_inverted_index.groove | 125 |
| abstract_inverted_index.helix, | 188 |
| abstract_inverted_index.immune | 43 |
| abstract_inverted_index.impact | 230 |
| abstract_inverted_index.lethal | 85 |
| abstract_inverted_index.possum | 21, 71, 80, 92, 238 |
| abstract_inverted_index.series | 69 |
| abstract_inverted_index.shared | 161 |
| abstract_inverted_index.wobbly | 79 |
| abstract_inverted_index.(WPDV), | 83 |
| abstract_inverted_index.Residue | 181 |
| abstract_inverted_index.binding | 75, 124 |
| abstract_inverted_index.captive | 89 |
| abstract_inverted_index.derived | 77 |
| abstract_inverted_index.disease | 81 |
| abstract_inverted_index.emerged | 176 |
| abstract_inverted_index.encoded | 33 |
| abstract_inverted_index.hotspot | 172 |
| abstract_inverted_index.include | 10 |
| abstract_inverted_index.located | 119, 184 |
| abstract_inverted_index.nothing | 49 |
| abstract_inverted_index.peptide | 54, 123, 205 |
| abstract_inverted_index.pivotal | 132 |
| abstract_inverted_index.similar | 152 |
| abstract_inverted_index.species | 26, 236 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Notably, | 103 |
| abstract_inverted_index.WPDV-12. | 206 |
| abstract_inverted_index.adaptive | 42, 215 |
| abstract_inverted_index.complex. | 102 |
| abstract_inverted_index.features | 56 |
| abstract_inverted_index.findings | 208, 225 |
| abstract_inverted_index.immunity | 216 |
| abstract_inverted_index.lineages | 8 |
| abstract_inverted_index.peptides | 76 |
| abstract_inverted_index.species. | 242 |
| abstract_inverted_index.terminus | 141 |
| abstract_inverted_index.unveiled | 95 |
| abstract_inverted_index.Molecules | 32 |
| abstract_inverted_index.anchoring | 203 |
| abstract_inverted_index.available | 190 |
| abstract_inverted_index.brushtail | 20, 108, 237 |
| abstract_inverted_index.essential | 39 |
| abstract_inverted_index.evolution | 171, 221 |
| abstract_inverted_index.important | 24 |
| abstract_inverted_index.influence | 199 |
| abstract_inverted_index.insertion | 129 |
| abstract_inverted_index.mammalian | 7 |
| abstract_inverted_index.marsupial | 19, 59, 99, 148, 241 |
| abstract_inverted_index.mediators | 40 |
| abstract_inverted_index.placental | 12 |
| abstract_inverted_index.potential | 228 |
| abstract_inverted_index.promoting | 201 |
| abstract_inverted_index.protected | 25, 235 |
| abstract_inverted_index.responses | 44 |
| abstract_inverted_index.stability | 137 |
| abstract_inverted_index.structure | 97 |
| abstract_inverted_index.Australian | 29 |
| abstract_inverted_index.Marsupials | 1 |
| abstract_inverted_index.ecosystem. | 31 |
| abstract_inverted_index.egg-laying | 16 |
| abstract_inverted_index.eutherians | 13 |
| abstract_inverted_index.identified | 67 |
| abstract_inverted_index.indicating | 169 |
| abstract_inverted_index.insertion, | 183 |
| abstract_inverted_index.insertions | 117 |
| abstract_inverted_index.marsupials | 218 |
| abstract_inverted_index.monotreme, | 168 |
| abstract_inverted_index.particular | 198 |
| abstract_inverted_index.insertions, | 110 |
| abstract_inverted_index.maintaining | 135 |
| abstract_inverted_index.monotremes. | 17 |
| abstract_inverted_index.peptide/MHC | 100 |
| abstract_inverted_index.vertebrates | 164 |
| abstract_inverted_index.Ptal-N*01:01 | 158 |
| abstract_inverted_index.conservation | 232 |
| abstract_inverted_index.elasmobranch | 166 |
| abstract_inverted_index.populations, | 93 |
| abstract_inverted_index.presentation | 55 |
| abstract_inverted_index.recognition, | 193 |
| abstract_inverted_index.unexpectedly | 151 |
| abstract_inverted_index.vertebrates. | 223 |
| abstract_inverted_index.virus–host | 46 |
| abstract_inverted_index.Trvu-UB*01:01 | 74, 122, 143 |
| abstract_inverted_index.interactions. | 47, 180 |
| abstract_inverted_index.significantly | 210 |
| abstract_inverted_index.understanding | 213 |
| abstract_inverted_index.Ile52Glu53Arg54 | 113 |
| abstract_inverted_index.pathogen–host | 179 |
| abstract_inverted_index.possum–specific | 109 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 16 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/15 |
| sustainable_development_goals[0].score | 0.7400000095367432 |
| sustainable_development_goals[0].display_name | Life in Land |
| citation_normalized_percentile.value | 0.77303689 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |