Pericarditis recurrence is associated with milder electrocardiographic, echocardiographic, and laboratory findings Article Swipe
T Weiss
,
Edward Itelman
,
Dor Lotan
,
Amitai Segev
,
Dov Freimark
,
Michael Arad
,
Yishay Wasserstrum
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1007/s11739-024-03579-7
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1007/s11739-024-03579-7
Recurrent pericarditis (RP) complicates approximately 30% of acute pericarditis (AP) cases. We sought to compare the prevalence and severity of objective findings seen in patients with RP. A retrospective single-center study during 2010–2019, including 765 patients diagnosed with AP. Clinical, electrocardiographic, echocardiographic, and laboratory findings were extracted from the local electronic health records. Recurrence during follow-up was documented in 134 patients (17.5%), with a median time to recurrence of 101 (± 59–251) days. The median age was 60 years (IQR 45–72), 68% were male. Most patients were defined as having idiopathic\viral pericarditis (64%). The clinical manifestation during the recurrent event of pericarditis was less prominent or attenuated when compared to the initial event—ECG signs (ST elevation 12% vs. 26%; p = 0.006, Knuckle sign 13% vs. 33%; p < 0.001, ST larger in lead L2 than L3 4% vs. 19%; p < 0.001), pericardial effusion moderate and above (11% vs. 30%; p = 0.02), and inflammatory markers (mean peak CRP levels 66 mg/l vs. 97 mg/l; p < 0.001). Similar results were seen in the subgroup of patients defined as having idiopathic\viral pericarditis. Up to 20% of patients who did not have ECG signs or a significant pericardial effusion in their 1st event demonstrated these findings during the recurrence, though still to a lesser extent compared with those who had these signs in their 1st event. The objective findings of AP are less pronounced during recurrent events. Future studies should focus on the role of advanced biomarkers and imaging in defining true RP events.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1007/s11739-024-03579-7
- https://link.springer.com/content/pdf/10.1007/s11739-024-03579-7.pdf
- OA Status
- hybrid
- Cited By
- 2
- References
- 20
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4393310863
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4393310863Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1007/s11739-024-03579-7Digital Object Identifier
- Title
-
Pericarditis recurrence is associated with milder electrocardiographic, echocardiographic, and laboratory findingsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-03-29Full publication date if available
- Authors
-
T Weiss, Edward Itelman, Dor Lotan, Amitai Segev, Dov Freimark, Michael Arad, Yishay WasserstrumList of authors in order
- Landing page
-
https://doi.org/10.1007/s11739-024-03579-7Publisher landing page
- PDF URL
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https://link.springer.com/content/pdf/10.1007/s11739-024-03579-7.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://link.springer.com/content/pdf/10.1007/s11739-024-03579-7.pdfDirect OA link when available
- Concepts
-
Medicine, Pericarditis, Pericardial effusion, Internal medicine, Retrospective cohort study, Cardiology, Acute pericarditis, Effusion, Electrocardiography, Cardiovascular event, Surgery, Myocardial infarctionTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2024: 1Per-year citation counts (last 5 years)
- References (count)
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20Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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