Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United States Article Swipe
Camilo Obando
,
Zhijie Ding
,
Erik Muser
,
Neel Vaidya
,
Wenqin Qiang
,
Xiaoxi Sun
,
Huiqi Wang
,
Rajesh Mallampati
,
Lin Xie
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1007/s12325-020-01276-3
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1007/s12325-020-01276-3
The majority of CD patients prescribed UST were biologic experienced, and persistence was high over the 1-year follow-up. UST treatment initiation was associated with reductions in ER visits, inpatient stays, and steroid and other medication use.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1007/s12325-020-01276-3
- https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdf
- OA Status
- hybrid
- Cited By
- 25
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3011039864
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3011039864Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1007/s12325-020-01276-3Digital Object Identifier
- Title
-
Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United StatesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-03-19Full publication date if available
- Authors
-
Camilo Obando, Zhijie Ding, Erik Muser, Neel Vaidya, Wenqin Qiang, Xiaoxi Sun, Huiqi Wang, Rajesh Mallampati, Lin XieList of authors in order
- Landing page
-
https://doi.org/10.1007/s12325-020-01276-3Publisher landing page
- PDF URL
-
https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdfDirect OA link when available
- Concepts
-
Medicine, Ustekinumab, Pharmacy, Crohn's disease, Internal medicine, Mallinckrodt, Disease, Pediatrics, Infliximab, Family medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
25Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 6, 2023: 6, 2022: 4, 2021: 7Per-year citation counts (last 5 years)
- References (count)
-
36Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3011039864 |
|---|---|
| doi | https://doi.org/10.1007/s12325-020-01276-3 |
| ids.doi | https://doi.org/10.1007/s12325-020-01276-3 |
| ids.mag | 3011039864 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/32193810 |
| ids.openalex | https://openalex.org/W3011039864 |
| fwci | 3.30824174 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000293 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Adolescent |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D000328 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Adult |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D000368 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Aged |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D000369 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Aged, 80 and over |
| mesh[4].qualifier_ui | Q000188 |
| mesh[4].descriptor_ui | D003424 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | drug therapy |
| mesh[4].descriptor_name | Crohn Disease |
| mesh[5].qualifier_ui | Q000191 |
| mesh[5].descriptor_ui | D003424 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | economics |
| mesh[5].descriptor_name | Crohn Disease |
| mesh[6].qualifier_ui | Q000453 |
| mesh[6].descriptor_ui | D003424 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | epidemiology |
| mesh[6].descriptor_name | Crohn Disease |
| mesh[7].qualifier_ui | Q000191 |
| mesh[7].descriptor_ui | D003695 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | economics |
| mesh[7].descriptor_name | Delivery of Health Care |
| mesh[8].qualifier_ui | Q000706 |
| mesh[8].descriptor_ui | D003695 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | statistics & numerical data |
| mesh[8].descriptor_name | Delivery of Health Care |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D005260 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Female |
| mesh[10].qualifier_ui | Q000706 |
| mesh[10].descriptor_ui | D017048 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | statistics & numerical data |
| mesh[10].descriptor_name | Health Care Costs |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D006801 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Humans |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D008297 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Male |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D008875 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Middle Aged |
| mesh[14].qualifier_ui | Q000706 |
| mesh[14].descriptor_ui | D010342 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | statistics & numerical data |
| mesh[14].descriptor_name | Patient Acceptance of Health Care |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D012189 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Retrospective Studies |
| mesh[16].qualifier_ui | Q000453 |
| mesh[16].descriptor_ui | D014481 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | epidemiology |
| mesh[16].descriptor_name | United States |
| mesh[17].qualifier_ui | Q000191 |
| mesh[17].descriptor_ui | D000069549 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | economics |
| mesh[17].descriptor_name | Ustekinumab |
| mesh[18].qualifier_ui | Q000627 |
| mesh[18].descriptor_ui | D000069549 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | therapeutic use |
| mesh[18].descriptor_name | Ustekinumab |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D055815 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Young Adult |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D000293 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Adolescent |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D000328 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Adult |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D000368 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Aged |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D000369 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Aged, 80 and over |
| mesh[24].qualifier_ui | Q000188 |
| mesh[24].descriptor_ui | D003424 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | drug therapy |
| mesh[24].descriptor_name | Crohn Disease |
| mesh[25].qualifier_ui | Q000191 |
| mesh[25].descriptor_ui | D003424 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | economics |
| mesh[25].descriptor_name | Crohn Disease |
| mesh[26].qualifier_ui | Q000453 |
| mesh[26].descriptor_ui | D003424 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | epidemiology |
| mesh[26].descriptor_name | Crohn Disease |
| mesh[27].qualifier_ui | Q000191 |
| mesh[27].descriptor_ui | D003695 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | economics |
| mesh[27].descriptor_name | Delivery of Health Care |
| mesh[28].qualifier_ui | Q000706 |
| mesh[28].descriptor_ui | D003695 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | statistics & numerical data |
| mesh[28].descriptor_name | Delivery of Health Care |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D005260 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Female |
| mesh[30].qualifier_ui | Q000706 |
| mesh[30].descriptor_ui | D017048 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | statistics & numerical data |
| mesh[30].descriptor_name | Health Care Costs |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D006801 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Humans |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D008297 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Male |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D008875 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Middle Aged |
| mesh[34].qualifier_ui | Q000706 |
| mesh[34].descriptor_ui | D010342 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | statistics & numerical data |
| mesh[34].descriptor_name | Patient Acceptance of Health Care |
| mesh[35].qualifier_ui | |
| mesh[35].descriptor_ui | D012189 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | |
| mesh[35].descriptor_name | Retrospective Studies |
| mesh[36].qualifier_ui | Q000453 |
| mesh[36].descriptor_ui | D014481 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | epidemiology |
| mesh[36].descriptor_name | United States |
| mesh[37].qualifier_ui | Q000191 |
| mesh[37].descriptor_ui | D000069549 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | economics |
| mesh[37].descriptor_name | Ustekinumab |
| mesh[38].qualifier_ui | Q000627 |
| mesh[38].descriptor_ui | D000069549 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | therapeutic use |
| mesh[38].descriptor_name | Ustekinumab |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D055815 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Young Adult |
| type | article |
| title | Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United States |
| biblio.issue | 5 |
| biblio.volume | 37 |
| biblio.last_page | 2143 |
| biblio.first_page | 2127 |
| grants[0].funder | https://openalex.org/F4320317188 |
| grants[0].award_id | |
| grants[0].funder_display_name | Janssen Scientific Affairs |
| topics[0].id | https://openalex.org/T10134 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | Inflammatory Bowel Disease |
| topics[1].id | https://openalex.org/T13569 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9962000250816345 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Microscopic Colitis |
| topics[2].id | https://openalex.org/T12538 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9962000250816345 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2746 |
| topics[2].subfield.display_name | Surgery |
| topics[2].display_name | Eosinophilic Esophagitis |
| funders[0].id | https://openalex.org/F4320317188 |
| funders[0].ror | |
| funders[0].display_name | Janssen Scientific Affairs |
| is_xpac | False |
| apc_list.value | 3390 |
| apc_list.currency | EUR |
| apc_list.value_usd | 4390 |
| apc_paid.value | 3390 |
| apc_paid.currency | EUR |
| apc_paid.value_usd | 4390 |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9548508524894714 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2778975655 |
| concepts[1].level | 4 |
| concepts[1].score | 0.740317165851593 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q420305 |
| concepts[1].display_name | Ustekinumab |
| concepts[2].id | https://openalex.org/C104863432 |
| concepts[2].level | 2 |
| concepts[2].score | 0.64378821849823 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q614304 |
| concepts[2].display_name | Pharmacy |
| concepts[3].id | https://openalex.org/C2779280984 |
| concepts[3].level | 3 |
| concepts[3].score | 0.5957794189453125 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q1472 |
| concepts[3].display_name | Crohn's disease |
| concepts[4].id | https://openalex.org/C126322002 |
| concepts[4].level | 1 |
| concepts[4].score | 0.5429099202156067 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[4].display_name | Internal medicine |
| concepts[5].id | https://openalex.org/C2910384678 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5400522351264954 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q6744211 |
| concepts[5].display_name | Mallinckrodt |
| concepts[6].id | https://openalex.org/C2779134260 |
| concepts[6].level | 2 |
| concepts[6].score | 0.39831775426864624 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q12136 |
| concepts[6].display_name | Disease |
| concepts[7].id | https://openalex.org/C187212893 |
| concepts[7].level | 1 |
| concepts[7].score | 0.3242034316062927 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q123028 |
| concepts[7].display_name | Pediatrics |
| concepts[8].id | https://openalex.org/C2777138892 |
| concepts[8].level | 3 |
| concepts[8].score | 0.10624617338180542 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q415264 |
| concepts[8].display_name | Infliximab |
| concepts[9].id | https://openalex.org/C512399662 |
| concepts[9].level | 1 |
| concepts[9].score | 0.09495505690574646 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q3505712 |
| concepts[9].display_name | Family medicine |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9548508524894714 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/ustekinumab |
| keywords[1].score | 0.740317165851593 |
| keywords[1].display_name | Ustekinumab |
| keywords[2].id | https://openalex.org/keywords/pharmacy |
| keywords[2].score | 0.64378821849823 |
| keywords[2].display_name | Pharmacy |
| keywords[3].id | https://openalex.org/keywords/crohns-disease |
| keywords[3].score | 0.5957794189453125 |
| keywords[3].display_name | Crohn's disease |
| keywords[4].id | https://openalex.org/keywords/internal-medicine |
| keywords[4].score | 0.5429099202156067 |
| keywords[4].display_name | Internal medicine |
| keywords[5].id | https://openalex.org/keywords/mallinckrodt |
| keywords[5].score | 0.5400522351264954 |
| keywords[5].display_name | Mallinckrodt |
| keywords[6].id | https://openalex.org/keywords/disease |
| keywords[6].score | 0.39831775426864624 |
| keywords[6].display_name | Disease |
| keywords[7].id | https://openalex.org/keywords/pediatrics |
| keywords[7].score | 0.3242034316062927 |
| keywords[7].display_name | Pediatrics |
| keywords[8].id | https://openalex.org/keywords/infliximab |
| keywords[8].score | 0.10624617338180542 |
| keywords[8].display_name | Infliximab |
| keywords[9].id | https://openalex.org/keywords/family-medicine |
| keywords[9].score | 0.09495505690574646 |
| keywords[9].display_name | Family medicine |
| language | en |
| locations[0].id | doi:10.1007/s12325-020-01276-3 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S27230875 |
| locations[0].source.issn | 0741-238X, 1865-8652 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0741-238X |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Advances in Therapy |
| locations[0].source.host_organization | https://openalex.org/P4310320330 |
| locations[0].source.host_organization_name | Adis, Springer Healthcare |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320330 |
| locations[0].license | cc-by-nc |
| locations[0].pdf_url | https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Advances in Therapy |
| locations[0].landing_page_url | https://doi.org/10.1007/s12325-020-01276-3 |
| locations[1].id | pmid:32193810 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Advances in therapy |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/32193810 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:7467496 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Adv Ther |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7467496 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5070143099 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Camilo Obando |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210151386, https://openalex.org/I4391767992 |
| authorships[0].affiliations[0].raw_affiliation_string | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[0].institutions[0].id | https://openalex.org/I4391767992 |
| authorships[0].institutions[0].ror | https://ror.org/04w4xsz15 |
| authorships[0].institutions[0].type | company |
| authorships[0].institutions[0].lineage | https://openalex.org/I1330063522, https://openalex.org/I4391767992 |
| authorships[0].institutions[0].country_code | |
| authorships[0].institutions[0].display_name | Janssen Scientific Affairs (United States) |
| authorships[0].institutions[1].id | https://openalex.org/I4210151386 |
| authorships[0].institutions[1].ror | https://ror.org/05af73403 |
| authorships[0].institutions[1].type | company |
| authorships[0].institutions[1].lineage | https://openalex.org/I1330063522, https://openalex.org/I4210151386 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | Janssen (United States) |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Camilo Obando |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[1].author.id | https://openalex.org/A5061242940 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-4290-4513 |
| authorships[1].author.display_name | Zhijie Ding |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210151386, https://openalex.org/I4391767992 |
| authorships[1].affiliations[0].raw_affiliation_string | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[1].institutions[0].id | https://openalex.org/I4391767992 |
| authorships[1].institutions[0].ror | https://ror.org/04w4xsz15 |
| authorships[1].institutions[0].type | company |
| authorships[1].institutions[0].lineage | https://openalex.org/I1330063522, https://openalex.org/I4391767992 |
| authorships[1].institutions[0].country_code | |
| authorships[1].institutions[0].display_name | Janssen Scientific Affairs (United States) |
| authorships[1].institutions[1].id | https://openalex.org/I4210151386 |
| authorships[1].institutions[1].ror | https://ror.org/05af73403 |
| authorships[1].institutions[1].type | company |
| authorships[1].institutions[1].lineage | https://openalex.org/I1330063522, https://openalex.org/I4210151386 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | Janssen (United States) |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Zhijie Ding |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[2].author.id | https://openalex.org/A5084091780 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Erik Muser |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210151386, https://openalex.org/I4391767992 |
| authorships[2].affiliations[0].raw_affiliation_string | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[2].institutions[0].id | https://openalex.org/I4391767992 |
| authorships[2].institutions[0].ror | https://ror.org/04w4xsz15 |
| authorships[2].institutions[0].type | company |
| authorships[2].institutions[0].lineage | https://openalex.org/I1330063522, https://openalex.org/I4391767992 |
| authorships[2].institutions[0].country_code | |
| authorships[2].institutions[0].display_name | Janssen Scientific Affairs (United States) |
| authorships[2].institutions[1].id | https://openalex.org/I4210151386 |
| authorships[2].institutions[1].ror | https://ror.org/05af73403 |
| authorships[2].institutions[1].type | company |
| authorships[2].institutions[1].lineage | https://openalex.org/I1330063522, https://openalex.org/I4210151386 |
| authorships[2].institutions[1].country_code | US |
| authorships[2].institutions[1].display_name | Janssen (United States) |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Erik Muser |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Real World Value & Evidence, Janssen Scientific Affairs LLC, Horsham, PA, USA |
| authorships[3].author.id | https://openalex.org/A5041258466 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-5697-5881 |
| authorships[3].author.display_name | Neel Vaidya |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[3].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[3].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[3].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[3].institutions[0].type | company |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | STATinMED (United States) |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Neel Vaidya |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[4].author.id | https://openalex.org/A5033867276 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Wenqin Qiang |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[4].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[4].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[4].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[4].institutions[0].type | company |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | STATinMED (United States) |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Wenqin Qiang |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[5].author.id | https://openalex.org/A5051161553 |
| authorships[5].author.orcid | https://orcid.org/0009-0002-2478-9889 |
| authorships[5].author.display_name | Xiaoxi Sun |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[5].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[5].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[5].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[5].institutions[0].type | company |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | STATinMED (United States) |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Xiaoxi Sun |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[6].author.id | https://openalex.org/A5009112260 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-7599-7349 |
| authorships[6].author.display_name | Huiqi Wang |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[6].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[6].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[6].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[6].institutions[0].type | company |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | STATinMED (United States) |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Huiqi Wang |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[7].author.id | https://openalex.org/A5084441134 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | Rajesh Mallampati |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[7].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[7].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[7].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[7].institutions[0].type | company |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | STATinMED (United States) |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Rajesh Mallampati |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[8].author.id | https://openalex.org/A5101475262 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-4689-8501 |
| authorships[8].author.display_name | Lin Xie |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210134263 |
| authorships[8].affiliations[0].raw_affiliation_string | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| authorships[8].institutions[0].id | https://openalex.org/I4210134263 |
| authorships[8].institutions[0].ror | https://ror.org/03r8cvf94 |
| authorships[8].institutions[0].type | company |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210134263 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | STATinMED (United States) |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | Lin Xie |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Health Economics and Outcomes Research, STATinMED Research, Ann Arbor, MI, USA |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdf |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Persistence, Dose Titration, and Health Care Resource Utilization Among Crohn’s Disease Patients Treated With Ustekinumab: A Real-World Analysis in the United States |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10134 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | Inflammatory Bowel Disease |
| related_works | https://openalex.org/W4396642851, https://openalex.org/W4376102407, https://openalex.org/W4282983262, https://openalex.org/W2463180023, https://openalex.org/W4383422124, https://openalex.org/W2993430338, https://openalex.org/W2791445493, https://openalex.org/W4281781548, https://openalex.org/W4283008514, https://openalex.org/W3206762024 |
| cited_by_count | 25 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 6 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 6 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 4 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 7 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1007/s12325-020-01276-3 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S27230875 |
| best_oa_location.source.issn | 0741-238X, 1865-8652 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0741-238X |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Advances in Therapy |
| best_oa_location.source.host_organization | https://openalex.org/P4310320330 |
| best_oa_location.source.host_organization_name | Adis, Springer Healthcare |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320330 |
| best_oa_location.license | cc-by-nc |
| best_oa_location.pdf_url | https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Advances in Therapy |
| best_oa_location.landing_page_url | https://doi.org/10.1007/s12325-020-01276-3 |
| primary_location.id | doi:10.1007/s12325-020-01276-3 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S27230875 |
| primary_location.source.issn | 0741-238X, 1865-8652 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0741-238X |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Advances in Therapy |
| primary_location.source.host_organization | https://openalex.org/P4310320330 |
| primary_location.source.host_organization_name | Adis, Springer Healthcare |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320330 |
| primary_location.license | cc-by-nc |
| primary_location.pdf_url | https://link.springer.com/content/pdf/10.1007/s12325-020-01276-3.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Advances in Therapy |
| primary_location.landing_page_url | https://doi.org/10.1007/s12325-020-01276-3 |
| publication_date | 2020-03-19 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W2794595980, https://openalex.org/W1996139830, https://openalex.org/W2624076097, https://openalex.org/W2105796913, https://openalex.org/W2084125637, https://openalex.org/W2045532520, https://openalex.org/W2045276152, https://openalex.org/W4242784814, https://openalex.org/W2312447916, https://openalex.org/W2017295150, https://openalex.org/W2887901349, https://openalex.org/W2528669148, https://openalex.org/W2143747121, https://openalex.org/W2902480298, https://openalex.org/W1997999969, https://openalex.org/W2131950421, https://openalex.org/W2034772721, https://openalex.org/W2024269361, https://openalex.org/W2153438195, https://openalex.org/W2324298557, https://openalex.org/W2554769268, https://openalex.org/W2801530489, https://openalex.org/W2132566002, https://openalex.org/W2080314829, https://openalex.org/W2041446227, https://openalex.org/W2027220172, https://openalex.org/W2039600415, https://openalex.org/W2605949011, https://openalex.org/W2026679422, https://openalex.org/W1544040470, https://openalex.org/W2921749306, https://openalex.org/W2619007242, https://openalex.org/W2921721497, https://openalex.org/W2799646319, https://openalex.org/W3151562918, https://openalex.org/W2111570058 |
| referenced_works_count | 36 |
| abstract_inverted_index.CD | 3 |
| abstract_inverted_index.ER | 26 |
| abstract_inverted_index.in | 25 |
| abstract_inverted_index.of | 2 |
| abstract_inverted_index.The | 0 |
| abstract_inverted_index.UST | 6, 18 |
| abstract_inverted_index.and | 10, 30, 32 |
| abstract_inverted_index.the | 15 |
| abstract_inverted_index.was | 12, 21 |
| abstract_inverted_index.high | 13 |
| abstract_inverted_index.over | 14 |
| abstract_inverted_index.use. | 35 |
| abstract_inverted_index.were | 7 |
| abstract_inverted_index.with | 23 |
| abstract_inverted_index.other | 33 |
| abstract_inverted_index.1-year | 16 |
| abstract_inverted_index.stays, | 29 |
| abstract_inverted_index.steroid | 31 |
| abstract_inverted_index.visits, | 27 |
| abstract_inverted_index.biologic | 8 |
| abstract_inverted_index.majority | 1 |
| abstract_inverted_index.patients | 4 |
| abstract_inverted_index.inpatient | 28 |
| abstract_inverted_index.treatment | 19 |
| abstract_inverted_index.associated | 22 |
| abstract_inverted_index.follow-up. | 17 |
| abstract_inverted_index.initiation | 20 |
| abstract_inverted_index.medication | 34 |
| abstract_inverted_index.prescribed | 5 |
| abstract_inverted_index.reductions | 24 |
| abstract_inverted_index.persistence | 11 |
| abstract_inverted_index.experienced, | 9 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 9 |
| citation_normalized_percentile.value | 0.91799436 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |