Phospholipids: Identification and Implication in Muscle Pathophysiology Article Swipe
Rezlène Bargui
,
Audrey Solgadi
,
Bastien Prost
,
Mélanie Chester
,
Ana Ferreiro
,
Jérôme Piquereau
,
Maryline Moulin
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/ijms22158176
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/ijms22158176
Phospholipids (PLs) are amphiphilic molecules that were essential for life to become cellular. PLs have not only a key role in compartmentation as they are the main components of membrane, but they are also involved in cell signaling, cell metabolism, and even cell pathophysiology. Considered for a long time to simply be structural elements of membranes, phospholipids are increasingly being viewed as sensors of their environment and regulators of many metabolic processes. After presenting their main characteristics, we expose the increasing methods of PL detection and identification that help to understand their key role in life processes. Interest and importance of PL homeostasis is growing as pathogenic variants in genes involved in PL biosynthesis and/or remodeling are linked to human diseases. We here review diseases that involve deregulation of PL homeostasis and present a predominantly muscular phenotype.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3390/ijms22158176
- https://www.mdpi.com/1422-0067/22/15/8176/pdf?version=1627624183
- OA Status
- gold
- Cited By
- 26
- References
- 146
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3185671208
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W3185671208Canonical identifier for this work in OpenAlex
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https://doi.org/10.3390/ijms22158176Digital Object Identifier
- Title
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Phospholipids: Identification and Implication in Muscle PathophysiologyWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-07-30Full publication date if available
- Authors
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Rezlène Bargui, Audrey Solgadi, Bastien Prost, Mélanie Chester, Ana Ferreiro, Jérôme Piquereau, Maryline MoulinList of authors in order
- Landing page
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https://doi.org/10.3390/ijms22158176Publisher landing page
- PDF URL
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https://www.mdpi.com/1422-0067/22/15/8176/pdf?version=1627624183Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://www.mdpi.com/1422-0067/22/15/8176/pdf?version=1627624183Direct OA link when available
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Homeostasis, Biology, Cell, Cell biology, Cell metabolism, Metabolic pathway, Phenotype, Identification (biology), Signal transduction, Cell signaling, Metabolism, Computational biology, Biochemistry, Gene, BotanyTop concepts (fields/topics) attached by OpenAlex
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26Total citation count in OpenAlex
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2025: 8, 2024: 4, 2023: 10, 2022: 4Per-year citation counts (last 5 years)
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146Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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