Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study Article Swipe
David C. Lauzier
,
Brandon Root
,
Yasha Kayan
,
Josser E Delgado Almandoz
,
Joshua W. Osbun
,
Arindam Chatterjee
,
Kayla L Whaley
,
Megan E. Tipps
,
Christopher J. Moran
,
Akash P. Kansagra
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1177/15910199211015578
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1177/15910199211015578
Background and purpose Flow diversion of aneurysms located in the M1 segment and middle cerebral artery bifurcation with Pipeline embolization device is sometimes performed, but further study is needed to support its regular use in aneurysm treatment. Here, we report measures of safety and efficacy for Pipeline embolization in the proximal middle cerebral artery in a multi-center cohort. Materials and methods Clinical and angiographic data of eligible patients were retrospectively obtained from participating centers and assessed for key clinical and angiographic outcomes. Additional details were extracted for patients with complications. Results In our multi-center cohort, complete aneurysm occlusion was achieved in 71% (17/24) of treated aneurysms. There were no deaths or disabling strokes, but non-disabling ischemic strokes occurred in 8% (2/24) of patients. For aneurysms in the M1 segment, complete aneurysm occlusion was observed in 75% (12/16) of aneurysms, aneurysm volume reduction was observed in 100% (16/16) of aneurysms, and non-disabling ischemic strokes occurred in 13% (2/16) of patients. For aneurysms at the middle cerebral artery bifurcation, complete aneurysm occlusion was observed in 63% (5/8) of aneurysms, aneurysm volume reduction occurred in 88% (7/8) of aneurysms, and ischemic or hemorrhagic complications occurred in 0% (0/8) of patients. Conclusion Pipeline embolization of cerebral aneurysms in the M1 segment and middle cerebral artery bifurcation demonstrated a 71% rate of complete aneurysm occlusion. There were no deaths or disabling strokes, but there was an 8% rate of non-disabling ischemic strokes.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/15910199211015578
- https://journals.sagepub.com/doi/pdf/10.1177/15910199211015578
- OA Status
- bronze
- Cited By
- 12
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3158866004
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Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3158866004Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1177/15910199211015578Digital Object Identifier
- Title
-
Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-05-05Full publication date if available
- Authors
-
David C. Lauzier, Brandon Root, Yasha Kayan, Josser E Delgado Almandoz, Joshua W. Osbun, Arindam Chatterjee, Kayla L Whaley, Megan E. Tipps, Christopher J. Moran, Akash P. KansagraList of authors in order
- Landing page
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https://doi.org/10.1177/15910199211015578Publisher landing page
- PDF URL
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https://journals.sagepub.com/doi/pdf/10.1177/15910199211015578Direct link to full text PDF
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YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
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https://journals.sagepub.com/doi/pdf/10.1177/15910199211015578Direct OA link when available
- Concepts
-
Medicine, Aneurysm, Embolization, Middle cerebral artery, Occlusion, Radiology, Cohort, Surgery, Cardiology, Internal medicine, IschemiaTop concepts (fields/topics) attached by OpenAlex
- Cited by
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12Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2, 2024: 2, 2023: 6, 2022: 1, 2021: 1Per-year citation counts (last 5 years)
- References (count)
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46Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.bifurcation, | 166 |
| abstract_inverted_index.demonstrated | 212 |
| abstract_inverted_index.embolization | 19, 47, 199 |
| abstract_inverted_index.multi-center | 56, 93 |
| abstract_inverted_index.complications | 190 |
| abstract_inverted_index.non-disabling | 114, 150, 234 |
| abstract_inverted_index.participating | 72 |
| abstract_inverted_index.complications. | 89 |
| abstract_inverted_index.retrospectively | 69 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5085188789 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 10 |
| corresponding_institution_ids | https://openalex.org/I204465549, https://openalex.org/I4210102181, https://openalex.org/I4210157890 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7900000214576721 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.79931669 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |